3BO5A

Crystal structure of methyltransferase domain of human histone-lysine n-methyltransferase setmar
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
279
structure length
269
Chain Sequence
TEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSASKERLDHGKLRKPCYCGAKSCTAFLPFDSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Methyltransferase Domain of Human Histone-lysine N-methyltransferase SETMAR in Complex With AdoHcy.
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Histone-lysine N-methyltransferase SETMAR
total genus 71
structure length 269
sequence length 279
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2007-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 3bo5A00
1MT6A 3CBPA 3OXFA 5T5GA 3N71A 5KJMA 5F59A 4QEOA 5LSXA 5CCLA 5F6LA 5F6KC 3QWWA 4J8OA 3MO0A 3RAYA 4FMUA 3M54A 4AU7A 3CBMA 2G46A 2IGQA 1MVXA 4IJDA 4J7IA 5CPRB 3VV0A 3F9WA 5T0MA 3M59A 3OXLA 3M56A 5CCMA 3M53A 4O6FA 3FPDA 4J83A 5KJKA 3QWPA 3PDNA 1MVHA 4C1QA 3S7DA 4JLGA 5KJLA 5F5EA 3OXGA 2W5YA 5LSZA 1N3JA 5HI7A 4NVQA 3BO5A 3K5KA 3QWVA 3MEKA 3S8PA 1XQHA 3M58A 3KMJA 4RZ0A 3M55A 4NJ5A 1O9SA 1ML9A 4H12A 4YPEA 5AYFA 5TH7A 4BUPA 1N6AA 5T0KA 3DALA 1MUFA 2W5ZA 4J7FA 3DB5A 4JDSA 4QEPA 3M5AA 5EX0A 2JV0A 4IJ8A 3RU0A 3KMTA 1PEGA 2O8JA 5ARFA 5JINA 5TTFA 3VUZA 3S7FA 3RJWA 3OS5A 3MO5A 3KMAA 4WUYA 3MO2A 4I51A 3F9ZA 5KJNA 3SWCA 5JHNA 3S7JA 2BQZA 3TG4A 4Z4PA 5EG2A 5HQ8A 3S7BA 4O30A 1H3IA 2F69A 3CBOA 3RQ4A 3HNAA 3RIBA 4E47A 3OOIA 5EX3A 4QENA 3IHXA 4MI0A 5JJ0A 3OPEA 1N6CA 2QPWA 4YNDA 4YNMA 5TEGA 3SW9A 3EP0A 3M57A 4YPAA 4YPUA 3F9YA 4LDGA 4YNPA 5ARGA 2R3AA 3F9XA 1ZKKA 4MI5A 3TG5A 5JIYA 2RFIA
chains in the Genus database with same CATH superfamily
1MT6A 3CBPA 3OXFA 5T5GA 3N71A 5KJMA 5F59A 4QEOA 5LSXA 5CCLA 5F6LA 5F6KC 3QWWA 4J8OA 3MO0A 3RAYA 4FMUA 3M54A 4AU7A 3CBMA 2G46A 2IGQA 1MVXA 4IJDA 4J7IA 5CPRB 3VV0A 3F9WA 5T0MA 3M59A 3OXLA 3M56A 5CCMA 3M53A 4O6FA 3FPDA 4J83A 5KJKA 3QWPA 3PDNA 1MVHA 4C1QA 3S7DA 4JLGA 5KJLA 5F5EA 3OXGA 2W5YA 5LSZA 1N3JA 5HI7A 4NVQA 3BO5A 3K5KA 3QWVA 3MEKA 3S8PA 1XQHA 3M58A 3KMJA 4RZ0A 3M55A 4NJ5A 1O9SA 1ML9A 4H12A 4YPEA 5AYFA 5TH7A 4BUPA 1N6AA 5T0KA 3DALA 1MUFA 2W5ZA 4J7FA 3DB5A 4JDSA 4QEPA 3M5AA 5EX0A 2JV0A 4IJ8A 3RU0A 3KMTA 1PEGA 2O8JA 5ARFA 5JINA 5TTFA 3VUZA 3S7FA 3RJWA 3OS5A 3MO5A 3KMAA 4WUYA 3MO2A 4I51A 3F9ZA 5KJNA 3SWCA 5JHNA 3S7JA 2BQZA 3TG4A 4Z4PA 5EG2A 5HQ8A 3S7BA 4O30A 1H3IA 2F69A 3CBOA 3RQ4A 3HNAA 3RIBA 4E47A 3OOIA 5EX3A 4QENA 3IHXA 4MI0A 5JJ0A 3OPEA 1N6CA 2QPWA 4YNDA 4YNMA 5TEGA 3SW9A 3EP0A 3M57A 4YPAA 4YPUA 3F9YA 4LDGA 4YNPA 5ARGA 2R3AA 3F9XA 1ZKKA 4MI5A 3TG5A 5JIYA 2RFIA
chains in the Genus database with same CATH topology
1MT6A 3CBPA 3OXFA 5T5GA 3N71A 5KJMA 5F59A 4QEOA 5LSXA 5CCLA 5F6LA 5F6KC 3QWWA 4J8OA 3MO0A 3RAYA 4FMUA 3M54A 4AU7A 3CBMA 2G46A 2IGQA 1MVXA 4IJDA 4J7IA 5CPRB 3VV0A 3F9WA 5T0MA 3M59A 3OXLA 3M56A 5CCMA 3M53A 4O6FA 3FPDA 4J83A 5KJKA 3QWPA 3PDNA 1MVHA 4C1QA 3S7DA 4JLGA 5KJLA 5F5EA 3OXGA 2W5YA 5LSZA 1N3JA 5HI7A 4NVQA 3BO5A 3K5KA 3QWVA 3MEKA 3S8PA 1XQHA 3M58A 3KMJA 4RZ0A 3M55A 4NJ5A 1O9SA 1ML9A 4H12A 4YPEA 5AYFA 5TH7A 4BUPA 1N6AA 5T0KA 3DALA 1MUFA 2W5ZA 4J7FA 3DB5A 4JDSA 4QEPA 3M5AA 5EX0A 2JV0A 4IJ8A 3RU0A 3KMTA 1PEGA 2O8JA 5ARFA 5JINA 5TTFA 3VUZA 3S7FA 3RJWA 3OS5A 3MO5A 3KMAA 4WUYA 3MO2A 4I51A 3F9ZA 5KJNA 3SWCA 5JHNA 3S7JA 2BQZA 3TG4A 4Z4PA 5EG2A 5HQ8A 3S7BA 4O30A 1H3IA 2F69A 3CBOA 3RQ4A 3HNAA 3RIBA 4E47A 3OOIA 5EX3A 4QENA 3IHXA 4MI0A 5JJ0A 3OPEA 1N6CA 2QPWA 4YNDA 4YNMA 5TEGA 3SW9A 3EP0A 3M57A 4YPAA 4YPUA 3F9YA 4LDGA 4YNPA 5ARGA 2R3AA 3F9XA 1ZKKA 4MI5A 3TG5A 5JIYA 2RFIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MT6 A;  3CBP A;  3OXF A;  5T5G A;  3N71 A;  5KJM A;  5F59 A;  4QEO A;  5LSX A;  5CCL A;  5F6L A;  5F6K C;  3QWW A;  4J8O A;  3MO0 A;  3RAY A;  4FMU A;  3M54 A;  4AU7 A;  3CBM A;  2G46 A;  2IGQ A;  1MVX A;  4IJD A;  4J7I A;  5CPR B;  3VV0 A;  3F9W A;  5T0M A;  3M59 A;  3OXL A;  3M56 A;  5CCM A;  3M53 A;  4O6F A;  3FPD A;  4J83 A;  5KJK A;  3QWP A;  3PDN A;  1MVH A;  4C1Q A;  3S7D A;  4JLG A;  5KJL A;  5F5E A;  3OXG A;  2W5Y A;  5LSZ A;  1N3J A;  5HI7 A;  4NVQ A;  3BO5 A;  3K5K A;  3QWV A;  3MEK A;  3S8P A;  1XQH A;  3M58 A;  3KMJ A;  4RZ0 A;  3M55 A;  4NJ5 A;  1O9S A;  1ML9 A;  4H12 A;  4YPE A;  5AYF A;  5TH7 A;  4BUP A;  1N6A A;  5T0K A;  3DAL A;  1MUF A;  2W5Z A;  4J7F A;  3DB5 A;  4JDS A;  4QEP A;  3M5A A;  5EX0 A;  2JV0 A;  4IJ8 A;  3RU0 A;  3KMT A;  1PEG A;  2O8J A;  5ARF A;  5JIN A;  5TTF A;  3VUZ A;  3S7F A;  3RJW A;  3OS5 A;  3MO5 A;  3KMA A;  4WUY A;  3MO2 A;  4I51 A;  3F9Z A;  5KJN A;  3SWC A;  5JHN A;  3S7J A;  2BQZ A;  3TG4 A;  4Z4P A;  5EG2 A;  5HQ8 A;  3S7B A;  4O30 A;  1H3I A;  2F69 A;  3CBO A;  3RQ4 A;  3HNA A;  3RIB A;  4E47 A;  3OOI A;  5EX3 A;  4QEN A;  3IHX A;  4MI0 A;  5JJ0 A;  3OPE A;  1N6C A;  2QPW A;  4YND A;  4YNM A;  5TEG A;  3SW9 A;  3EP0 A;  3M57 A;  4YPA A;  4YPU A;  3F9Y A;  4LDG A;  4YNP A;  5ARG A;  2R3A A;  3F9X A;  1ZKK A;  4MI5 A;  3TG5 A;  5JIY A;  2RFI A; 
#chains in the Genus database with same CATH topology
 1MT6 A;  3CBP A;  3OXF A;  5T5G A;  3N71 A;  5KJM A;  5F59 A;  4QEO A;  5LSX A;  5CCL A;  5F6L A;  5F6K C;  3QWW A;  4J8O A;  3MO0 A;  3RAY A;  4FMU A;  3M54 A;  4AU7 A;  3CBM A;  2G46 A;  2IGQ A;  1MVX A;  4IJD A;  4J7I A;  5CPR B;  3VV0 A;  3F9W A;  5T0M A;  3M59 A;  3OXL A;  3M56 A;  5CCM A;  3M53 A;  4O6F A;  3FPD A;  4J83 A;  5KJK A;  3QWP A;  3PDN A;  1MVH A;  4C1Q A;  3S7D A;  4JLG A;  5KJL A;  5F5E A;  3OXG A;  2W5Y A;  5LSZ A;  1N3J A;  5HI7 A;  4NVQ A;  3BO5 A;  3K5K A;  3QWV A;  3MEK A;  3S8P A;  1XQH A;  3M58 A;  3KMJ A;  4RZ0 A;  3M55 A;  4NJ5 A;  1O9S A;  1ML9 A;  4H12 A;  4YPE A;  5AYF A;  5TH7 A;  4BUP A;  1N6A A;  5T0K A;  3DAL A;  1MUF A;  2W5Z A;  4J7F A;  3DB5 A;  4JDS A;  4QEP A;  3M5A A;  5EX0 A;  2JV0 A;  4IJ8 A;  3RU0 A;  3KMT A;  1PEG A;  2O8J A;  5ARF A;  5JIN A;  5TTF A;  3VUZ A;  3S7F A;  3RJW A;  3OS5 A;  3MO5 A;  3KMA A;  4WUY A;  3MO2 A;  4I51 A;  3F9Z A;  5KJN A;  3SWC A;  5JHN A;  3S7J A;  2BQZ A;  3TG4 A;  4Z4P A;  5EG2 A;  5HQ8 A;  3S7B A;  4O30 A;  1H3I A;  2F69 A;  3CBO A;  3RQ4 A;  3HNA A;  3RIB A;  4E47 A;  3OOI A;  5EX3 A;  4QEN A;  3IHX A;  4MI0 A;  5JJ0 A;  3OPE A;  1N6C A;  2QPW A;  4YND A;  4YNM A;  5TEG A;  3SW9 A;  3EP0 A;  3M57 A;  4YPA A;  4YPU A;  3F9Y A;  4LDG A;  4YNP A;  5ARG A;  2R3A A;  3F9X A;  1ZKK A;  4MI5 A;  3TG5 A;  5JIY A;  2RFI A; 
#chains in the Genus database with same CATH homology
 1MT6 A;  3CBP A;  3OXF A;  5T5G A;  3N71 A;  5KJM A;  5F59 A;  4QEO A;  5LSX A;  5CCL A;  5F6L A;  5F6K C;  3QWW A;  4J8O A;  3MO0 A;  3RAY A;  4FMU A;  3M54 A;  4AU7 A;  3CBM A;  2G46 A;  2IGQ A;  1MVX A;  4IJD A;  4J7I A;  5CPR B;  3VV0 A;  3F9W A;  5T0M A;  3M59 A;  3OXL A;  3M56 A;  5CCM A;  3M53 A;  4O6F A;  3FPD A;  4J83 A;  5KJK A;  3QWP A;  3PDN A;  1MVH A;  4C1Q A;  3S7D A;  4JLG A;  5KJL A;  5F5E A;  3OXG A;  2W5Y A;  5LSZ A;  1N3J A;  5HI7 A;  4NVQ A;  3BO5 A;  3K5K A;  3QWV A;  3MEK A;  3S8P A;  1XQH A;  3M58 A;  3KMJ A;  4RZ0 A;  3M55 A;  4NJ5 A;  1O9S A;  1ML9 A;  4H12 A;  4YPE A;  5AYF A;  5TH7 A;  4BUP A;  1N6A A;  5T0K A;  3DAL A;  1MUF A;  2W5Z A;  4J7F A;  3DB5 A;  4JDS A;  4QEP A;  3M5A A;  5EX0 A;  2JV0 A;  4IJ8 A;  3RU0 A;  3KMT A;  1PEG A;  2O8J A;  5ARF A;  5JIN A;  5TTF A;  3VUZ A;  3S7F A;  3RJW A;  3OS5 A;  3MO5 A;  3KMA A;  4WUY A;  3MO2 A;  4I51 A;  3F9Z A;  5KJN A;  3SWC A;  5JHN A;  3S7J A;  2BQZ A;  3TG4 A;  4Z4P A;  5EG2 A;  5HQ8 A;  3S7B A;  4O30 A;  1H3I A;  2F69 A;  3CBO A;  3RQ4 A;  3HNA A;  3RIB A;  4E47 A;  3OOI A;  5EX3 A;  4QEN A;  3IHX A;  4MI0 A;  5JJ0 A;  3OPE A;  1N6C A;  2QPW A;  4YND A;  4YNM A;  5TEG A;  3SW9 A;  3EP0 A;  3M57 A;  4YPA A;  4YPU A;  3F9Y A;  4LDG A;  4YNP A;  5ARG A;  2R3A A;  3F9X A;  1ZKK A;  4MI5 A;  3TG5 A;  5JIY A;  2RFI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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