3BO5A

Crystal structure of methyltransferase domain of human histone-lysine n-methyltransferase setmar
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
279
structure length
269
Chain Sequence
TEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSASKERLDHGKLRKPCYCGAKSCTAFLPFDSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Methyltransferase Domain of Human Histone-lysine N-methyltransferase SETMAR in Complex With AdoHcy.
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Histone-lysine N-methyltransferase SETMAR
total genus 71
structure length 269
sequence length 279
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2007-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 3bo5A00
4YPUA 3MEKA 4H12A 5HQ8A 4QEOA 5F5EA 5CPRB 1H3IA 4J83A 3RAYA 1PEGA 3KMTA 5T0KA 5TTFA 3CBMA 3RIBA 2O8JA 5CCMA 5F6LA 3M53A 3QWPA 4YNMA 5T0MA 3OS5A 4J8OA 4NVQA 4YPEA 3MO5A 2G46A 5JINA 3M57A 5LSXA 3F9WA 3F9ZA 4LDGA 4QEPA 1MT6A 5JIYA 5F6KC 4WUYA 3M5AA 4JLGA 3M59A 5CCLA 5ARGA 4NJ5A 3VUZA 5KJKA 3OXLA 3N71A 5ARFA 4IJ8A 4YNDA 1MVXA 2BQZA 5KJLA 3S7DA 3KMJA 4IJDA 3OXFA 3RU0A 3M58A 2JV0A 4MI5A 1MVHA 3DB5A 3M54A 2R3AA 2F69A 3M55A 3VV0A 4J7IA 3F9YA 3CBOA 3QWVA 5JHNA 4RZ0A 5HI7A 2W5YA 3EP0A 5TEGA 4YPAA 3MO2A 3S7BA 3F9XA 3FPDA 3HNAA 1ZKKA 3DALA 3S7JA 1XQHA 5KJMA 4O6FA 4Z4PA 4C1QA 1MUFA 3M56A 1O9SA 3RQ4A 3OPEA 3PDNA 4AU7A 3SW9A 2QPWA 4J7FA 4BUPA 4JDSA 1N3JA 5KJNA 3QWWA 3S8PA 3K5KA 3S7FA 1ML9A 5AYFA 3OOIA 5LSZA 4MI0A 3MO0A 5T5GA 5EX3A 5EG2A 3OXGA 3SWCA 2RFIA 4I51A 5F59A 4O30A 2IGQA 5JJ0A 1N6CA 4E47A 2W5ZA 3BO5A 3TG5A 5EX0A 1N6AA 5TH7A 3TG4A 3KMAA 3IHXA 4FMUA 4QENA 3CBPA 4YNPA 3RJWA
chains in the Genus database with same CATH superfamily
4YPUA 3MEKA 4H12A 5HQ8A 4QEOA 5F5EA 5CPRB 1H3IA 4J83A 3RAYA 1PEGA 3KMTA 5T0KA 5TTFA 3CBMA 3RIBA 2O8JA 5CCMA 5F6LA 3M53A 3QWPA 4YNMA 5T0MA 3OS5A 4J8OA 4NVQA 4YPEA 3MO5A 2G46A 5JINA 3M57A 5LSXA 3F9WA 3F9ZA 4LDGA 4QEPA 1MT6A 5JIYA 5F6KC 4WUYA 3M5AA 4JLGA 3M59A 5CCLA 5ARGA 4NJ5A 3VUZA 5KJKA 3OXLA 3N71A 5ARFA 4IJ8A 4YNDA 1MVXA 2BQZA 5KJLA 3S7DA 3KMJA 4IJDA 3OXFA 3RU0A 3M58A 2JV0A 4MI5A 1MVHA 3DB5A 3M54A 2R3AA 2F69A 3M55A 3VV0A 4J7IA 3F9YA 3CBOA 3QWVA 5JHNA 4RZ0A 5HI7A 2W5YA 3EP0A 5TEGA 4YPAA 3MO2A 3S7BA 3F9XA 3FPDA 3HNAA 1ZKKA 3DALA 3S7JA 1XQHA 5KJMA 4O6FA 4Z4PA 4C1QA 1MUFA 3M56A 1O9SA 3RQ4A 3OPEA 3PDNA 4AU7A 3SW9A 2QPWA 4J7FA 4BUPA 4JDSA 1N3JA 5KJNA 3QWWA 3S8PA 3K5KA 3S7FA 1ML9A 5AYFA 3OOIA 5LSZA 4MI0A 3MO0A 5T5GA 5EX3A 5EG2A 3OXGA 3SWCA 2RFIA 4I51A 5F59A 4O30A 2IGQA 5JJ0A 1N6CA 4E47A 2W5ZA 3BO5A 3TG5A 5EX0A 1N6AA 5TH7A 3TG4A 3KMAA 3IHXA 4FMUA 4QENA 3CBPA 4YNPA 3RJWA
chains in the Genus database with same CATH topology
4YPUA 3MEKA 4H12A 5HQ8A 4QEOA 5F5EA 5CPRB 1H3IA 4J83A 3RAYA 1PEGA 3KMTA 5T0KA 5TTFA 3CBMA 3RIBA 2O8JA 5CCMA 5F6LA 3M53A 3QWPA 4YNMA 5T0MA 3OS5A 4J8OA 4NVQA 4YPEA 3MO5A 2G46A 5JINA 3M57A 5LSXA 3F9WA 3F9ZA 4LDGA 4QEPA 1MT6A 5JIYA 5F6KC 4WUYA 3M5AA 4JLGA 3M59A 5CCLA 5ARGA 4NJ5A 3VUZA 5KJKA 3OXLA 3N71A 5ARFA 4IJ8A 4YNDA 1MVXA 2BQZA 5KJLA 3S7DA 3KMJA 4IJDA 3OXFA 3RU0A 3M58A 2JV0A 4MI5A 1MVHA 3DB5A 3M54A 2R3AA 2F69A 3M55A 3VV0A 4J7IA 3F9YA 3CBOA 3QWVA 5JHNA 4RZ0A 5HI7A 2W5YA 3EP0A 5TEGA 4YPAA 3MO2A 3S7BA 3F9XA 3FPDA 3HNAA 1ZKKA 3DALA 3S7JA 1XQHA 5KJMA 4O6FA 4Z4PA 4C1QA 1MUFA 3M56A 1O9SA 3RQ4A 3OPEA 3PDNA 4AU7A 3SW9A 2QPWA 4J7FA 4BUPA 4JDSA 1N3JA 5KJNA 3QWWA 3S8PA 3K5KA 3S7FA 1ML9A 5AYFA 3OOIA 5LSZA 4MI0A 3MO0A 5T5GA 5EX3A 5EG2A 3OXGA 3SWCA 2RFIA 4I51A 5F59A 4O30A 2IGQA 5JJ0A 1N6CA 4E47A 2W5ZA 3BO5A 3TG5A 5EX0A 1N6AA 5TH7A 3TG4A 3KMAA 3IHXA 4FMUA 4QENA 3CBPA 4YNPA 3RJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPU A;  3MEK A;  4H12 A;  5HQ8 A;  4QEO A;  5F5E A;  5CPR B;  1H3I A;  4J83 A;  3RAY A;  1PEG A;  3KMT A;  5T0K A;  5TTF A;  3CBM A;  3RIB A;  2O8J A;  5CCM A;  5F6L A;  3M53 A;  3QWP A;  4YNM A;  5T0M A;  3OS5 A;  4J8O A;  4NVQ A;  4YPE A;  3MO5 A;  2G46 A;  5JIN A;  3M57 A;  5LSX A;  3F9W A;  3F9Z A;  4LDG A;  4QEP A;  1MT6 A;  5JIY A;  5F6K C;  4WUY A;  3M5A A;  4JLG A;  3M59 A;  5CCL A;  5ARG A;  4NJ5 A;  3VUZ A;  5KJK A;  3OXL A;  3N71 A;  5ARF A;  4IJ8 A;  4YND A;  1MVX A;  2BQZ A;  5KJL A;  3S7D A;  3KMJ A;  4IJD A;  3OXF A;  3RU0 A;  3M58 A;  2JV0 A;  4MI5 A;  1MVH A;  3DB5 A;  3M54 A;  2R3A A;  2F69 A;  3M55 A;  3VV0 A;  4J7I A;  3F9Y A;  3CBO A;  3QWV A;  5JHN A;  4RZ0 A;  5HI7 A;  2W5Y A;  3EP0 A;  5TEG A;  4YPA A;  3MO2 A;  3S7B A;  3F9X A;  3FPD A;  3HNA A;  1ZKK A;  3DAL A;  3S7J A;  1XQH A;  5KJM A;  4O6F A;  4Z4P A;  4C1Q A;  1MUF A;  3M56 A;  1O9S A;  3RQ4 A;  3OPE A;  3PDN A;  4AU7 A;  3SW9 A;  2QPW A;  4J7F A;  4BUP A;  4JDS A;  1N3J A;  5KJN A;  3QWW A;  3S8P A;  3K5K A;  3S7F A;  1ML9 A;  5AYF A;  3OOI A;  5LSZ A;  4MI0 A;  3MO0 A;  5T5G A;  5EX3 A;  5EG2 A;  3OXG A;  3SWC A;  2RFI A;  4I51 A;  5F59 A;  4O30 A;  2IGQ A;  5JJ0 A;  1N6C A;  4E47 A;  2W5Z A;  3BO5 A;  3TG5 A;  5EX0 A;  1N6A A;  5TH7 A;  3TG4 A;  3KMA A;  3IHX A;  4FMU A;  4QEN A;  3CBP A;  4YNP A;  3RJW A; 
#chains in the Genus database with same CATH topology
 4YPU A;  3MEK A;  4H12 A;  5HQ8 A;  4QEO A;  5F5E A;  5CPR B;  1H3I A;  4J83 A;  3RAY A;  1PEG A;  3KMT A;  5T0K A;  5TTF A;  3CBM A;  3RIB A;  2O8J A;  5CCM A;  5F6L A;  3M53 A;  3QWP A;  4YNM A;  5T0M A;  3OS5 A;  4J8O A;  4NVQ A;  4YPE A;  3MO5 A;  2G46 A;  5JIN A;  3M57 A;  5LSX A;  3F9W A;  3F9Z A;  4LDG A;  4QEP A;  1MT6 A;  5JIY A;  5F6K C;  4WUY A;  3M5A A;  4JLG A;  3M59 A;  5CCL A;  5ARG A;  4NJ5 A;  3VUZ A;  5KJK A;  3OXL A;  3N71 A;  5ARF A;  4IJ8 A;  4YND A;  1MVX A;  2BQZ A;  5KJL A;  3S7D A;  3KMJ A;  4IJD A;  3OXF A;  3RU0 A;  3M58 A;  2JV0 A;  4MI5 A;  1MVH A;  3DB5 A;  3M54 A;  2R3A A;  2F69 A;  3M55 A;  3VV0 A;  4J7I A;  3F9Y A;  3CBO A;  3QWV A;  5JHN A;  4RZ0 A;  5HI7 A;  2W5Y A;  3EP0 A;  5TEG A;  4YPA A;  3MO2 A;  3S7B A;  3F9X A;  3FPD A;  3HNA A;  1ZKK A;  3DAL A;  3S7J A;  1XQH A;  5KJM A;  4O6F A;  4Z4P A;  4C1Q A;  1MUF A;  3M56 A;  1O9S A;  3RQ4 A;  3OPE A;  3PDN A;  4AU7 A;  3SW9 A;  2QPW A;  4J7F A;  4BUP A;  4JDS A;  1N3J A;  5KJN A;  3QWW A;  3S8P A;  3K5K A;  3S7F A;  1ML9 A;  5AYF A;  3OOI A;  5LSZ A;  4MI0 A;  3MO0 A;  5T5G A;  5EX3 A;  5EG2 A;  3OXG A;  3SWC A;  2RFI A;  4I51 A;  5F59 A;  4O30 A;  2IGQ A;  5JJ0 A;  1N6C A;  4E47 A;  2W5Z A;  3BO5 A;  3TG5 A;  5EX0 A;  1N6A A;  5TH7 A;  3TG4 A;  3KMA A;  3IHX A;  4FMU A;  4QEN A;  3CBP A;  4YNP A;  3RJW A; 
#chains in the Genus database with same CATH homology
 4YPU A;  3MEK A;  4H12 A;  5HQ8 A;  4QEO A;  5F5E A;  5CPR B;  1H3I A;  4J83 A;  3RAY A;  1PEG A;  3KMT A;  5T0K A;  5TTF A;  3CBM A;  3RIB A;  2O8J A;  5CCM A;  5F6L A;  3M53 A;  3QWP A;  4YNM A;  5T0M A;  3OS5 A;  4J8O A;  4NVQ A;  4YPE A;  3MO5 A;  2G46 A;  5JIN A;  3M57 A;  5LSX A;  3F9W A;  3F9Z A;  4LDG A;  4QEP A;  1MT6 A;  5JIY A;  5F6K C;  4WUY A;  3M5A A;  4JLG A;  3M59 A;  5CCL A;  5ARG A;  4NJ5 A;  3VUZ A;  5KJK A;  3OXL A;  3N71 A;  5ARF A;  4IJ8 A;  4YND A;  1MVX A;  2BQZ A;  5KJL A;  3S7D A;  3KMJ A;  4IJD A;  3OXF A;  3RU0 A;  3M58 A;  2JV0 A;  4MI5 A;  1MVH A;  3DB5 A;  3M54 A;  2R3A A;  2F69 A;  3M55 A;  3VV0 A;  4J7I A;  3F9Y A;  3CBO A;  3QWV A;  5JHN A;  4RZ0 A;  5HI7 A;  2W5Y A;  3EP0 A;  5TEG A;  4YPA A;  3MO2 A;  3S7B A;  3F9X A;  3FPD A;  3HNA A;  1ZKK A;  3DAL A;  3S7J A;  1XQH A;  5KJM A;  4O6F A;  4Z4P A;  4C1Q A;  1MUF A;  3M56 A;  1O9S A;  3RQ4 A;  3OPE A;  3PDN A;  4AU7 A;  3SW9 A;  2QPW A;  4J7F A;  4BUP A;  4JDS A;  1N3J A;  5KJN A;  3QWW A;  3S8P A;  3K5K A;  3S7F A;  1ML9 A;  5AYF A;  3OOI A;  5LSZ A;  4MI0 A;  3MO0 A;  5T5G A;  5EX3 A;  5EG2 A;  3OXG A;  3SWC A;  2RFI A;  4I51 A;  5F59 A;  4O30 A;  2IGQ A;  5JJ0 A;  1N6C A;  4E47 A;  2W5Z A;  3BO5 A;  3TG5 A;  5EX0 A;  1N6A A;  5TH7 A;  3TG4 A;  3KMA A;  3IHX A;  4FMU A;  4QEN A;  3CBP A;  4YNP A;  3RJW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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