3SWCA

Glp (g9a-like protein) set domain in complex with dnmt3ak44me2 peptide
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
261
structure length
261
Chain Sequence
VERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Histone-lysine N-methyltransferase EHMT1
total genus 69
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 3swcA00
5T0KA 5HI7A 4JDSA 2F69A 3OXFA 4J83A 3DALA 3F9WA 4Z4PA 3RU0A 3M54A 3KMTA 5F6KC 5TEGA 5TH7A 5JINA 5KJNA 3RQ4A 3OS5A 1N6CA 3SW9A 3M5AA 4MI5A 5CCLA 3M57A 3BO5A 1MVXA 1N6AA 3OXGA 3HNAA 4IJ8A 3MO0A 3S7DA 3M58A 4FMUA 3S7BA 3CBOA 4YNDA 3TG5A 3MEKA 3S7JA 3PDNA 4YPEA 5HQ8A 5ARGA 2O8JA 4I51A 4IJDA 3RJWA 3SWCA 3K5KA 5EX3A 1MUFA 2W5ZA 3CBPA 3OPEA 5F59A 5T0MA 3IHXA 4C1QA 3FPDA 4YPUA 3KMJA 4YNPA 4J8OA 1ZKKA 4JLGA 3MO5A 3QWVA 5JJ0A 3M56A 1N3JA 1O9SA 1MT6A 4J7FA 5T5GA 3QWWA 4AU7A 4NVQA 3F9ZA 4O6FA 3VUZA 5KJMA 5AYFA 4WUYA 4YPAA 3MO2A 3QWPA 2BQZA 5ARFA 3CBMA 5F5EA 3F9XA 4QENA 5CCMA 2JV0A 3RIBA 2RFIA 3OOIA 3TG4A 2IGQA 5F6LA 4E47A 1MVHA 1H3IA 4MI0A 2QPWA 3M55A 2W5YA 5LSZA 4QEPA 1XQHA 5EG2A 1PEGA 3F9YA 5TTFA 3DB5A 3RAYA 3S7FA 5KJKA 5LSXA 3S8PA 3N71A 5CPRB 3OXLA 4YNMA 3M59A 4O30A 3EP0A 5EX0A 3M53A 4H12A 1ML9A 4J7IA 2R3AA 3KMAA 5KJLA 4BUPA 5JHNA 4RZ0A 5JIYA 2G46A 4LDGA 3VV0A 4QEOA 4NJ5A
chains in the Genus database with same CATH superfamily
5T0KA 5HI7A 4JDSA 2F69A 3OXFA 4J83A 3DALA 3F9WA 4Z4PA 3RU0A 3M54A 3KMTA 5F6KC 5TEGA 5TH7A 5JINA 5KJNA 3RQ4A 3OS5A 1N6CA 3SW9A 3M5AA 4MI5A 5CCLA 3M57A 3BO5A 1MVXA 1N6AA 3OXGA 3HNAA 4IJ8A 3MO0A 3S7DA 3M58A 4FMUA 3S7BA 3CBOA 4YNDA 3TG5A 3MEKA 3S7JA 3PDNA 4YPEA 5HQ8A 5ARGA 2O8JA 4I51A 4IJDA 3RJWA 3SWCA 3K5KA 5EX3A 1MUFA 2W5ZA 3CBPA 3OPEA 5F59A 5T0MA 3IHXA 4C1QA 3FPDA 4YPUA 3KMJA 4YNPA 4J8OA 1ZKKA 4JLGA 3MO5A 3QWVA 5JJ0A 3M56A 1N3JA 1O9SA 1MT6A 4J7FA 5T5GA 3QWWA 4AU7A 4NVQA 3F9ZA 4O6FA 3VUZA 5KJMA 5AYFA 4WUYA 4YPAA 3MO2A 3QWPA 2BQZA 5ARFA 3CBMA 5F5EA 3F9XA 4QENA 5CCMA 2JV0A 3RIBA 2RFIA 3OOIA 3TG4A 2IGQA 5F6LA 4E47A 1MVHA 1H3IA 4MI0A 2QPWA 3M55A 2W5YA 5LSZA 4QEPA 1XQHA 5EG2A 1PEGA 3F9YA 5TTFA 3DB5A 3RAYA 3S7FA 5KJKA 5LSXA 3S8PA 3N71A 5CPRB 3OXLA 4YNMA 3M59A 4O30A 3EP0A 5EX0A 3M53A 4H12A 1ML9A 4J7IA 2R3AA 3KMAA 5KJLA 4BUPA 5JHNA 4RZ0A 5JIYA 2G46A 4LDGA 3VV0A 4QEOA 4NJ5A
chains in the Genus database with same CATH topology
5T0KA 5HI7A 4JDSA 2F69A 3OXFA 4J83A 3DALA 3F9WA 4Z4PA 3RU0A 3M54A 3KMTA 5F6KC 5TEGA 5TH7A 5JINA 5KJNA 3RQ4A 3OS5A 1N6CA 3SW9A 3M5AA 4MI5A 5CCLA 3M57A 3BO5A 1MVXA 1N6AA 3OXGA 3HNAA 4IJ8A 3MO0A 3S7DA 3M58A 4FMUA 3S7BA 3CBOA 4YNDA 3TG5A 3MEKA 3S7JA 3PDNA 4YPEA 5HQ8A 5ARGA 2O8JA 4I51A 4IJDA 3RJWA 3SWCA 3K5KA 5EX3A 1MUFA 2W5ZA 3CBPA 3OPEA 5F59A 5T0MA 3IHXA 4C1QA 3FPDA 4YPUA 3KMJA 4YNPA 4J8OA 1ZKKA 4JLGA 3MO5A 3QWVA 5JJ0A 3M56A 1N3JA 1O9SA 1MT6A 4J7FA 5T5GA 3QWWA 4AU7A 4NVQA 3F9ZA 4O6FA 3VUZA 5KJMA 5AYFA 4WUYA 4YPAA 3MO2A 3QWPA 2BQZA 5ARFA 3CBMA 5F5EA 3F9XA 4QENA 5CCMA 2JV0A 3RIBA 2RFIA 3OOIA 3TG4A 2IGQA 5F6LA 4E47A 1MVHA 1H3IA 4MI0A 2QPWA 3M55A 2W5YA 5LSZA 4QEPA 1XQHA 5EG2A 1PEGA 3F9YA 5TTFA 3DB5A 3RAYA 3S7FA 5KJKA 5LSXA 3S8PA 3N71A 5CPRB 3OXLA 4YNMA 3M59A 4O30A 3EP0A 5EX0A 3M53A 4H12A 1ML9A 4J7IA 2R3AA 3KMAA 5KJLA 4BUPA 5JHNA 4RZ0A 5JIYA 2G46A 4LDGA 3VV0A 4QEOA 4NJ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5T0K A;  5HI7 A;  4JDS A;  2F69 A;  3OXF A;  4J83 A;  3DAL A;  3F9W A;  4Z4P A;  3RU0 A;  3M54 A;  3KMT A;  5F6K C;  5TEG A;  5TH7 A;  5JIN A;  5KJN A;  3RQ4 A;  3OS5 A;  1N6C A;  3SW9 A;  3M5A A;  4MI5 A;  5CCL A;  3M57 A;  3BO5 A;  1MVX A;  1N6A A;  3OXG A;  3HNA A;  4IJ8 A;  3MO0 A;  3S7D A;  3M58 A;  4FMU A;  3S7B A;  3CBO A;  4YND A;  3TG5 A;  3MEK A;  3S7J A;  3PDN A;  4YPE A;  5HQ8 A;  5ARG A;  2O8J A;  4I51 A;  4IJD A;  3RJW A;  3SWC A;  3K5K A;  5EX3 A;  1MUF A;  2W5Z A;  3CBP A;  3OPE A;  5F59 A;  5T0M A;  3IHX A;  4C1Q A;  3FPD A;  4YPU A;  3KMJ A;  4YNP A;  4J8O A;  1ZKK A;  4JLG A;  3MO5 A;  3QWV A;  5JJ0 A;  3M56 A;  1N3J A;  1O9S A;  1MT6 A;  4J7F A;  5T5G A;  3QWW A;  4AU7 A;  4NVQ A;  3F9Z A;  4O6F A;  3VUZ A;  5KJM A;  5AYF A;  4WUY A;  4YPA A;  3MO2 A;  3QWP A;  2BQZ A;  5ARF A;  3CBM A;  5F5E A;  3F9X A;  4QEN A;  5CCM A;  2JV0 A;  3RIB A;  2RFI A;  3OOI A;  3TG4 A;  2IGQ A;  5F6L A;  4E47 A;  1MVH A;  1H3I A;  4MI0 A;  2QPW A;  3M55 A;  2W5Y A;  5LSZ A;  4QEP A;  1XQH A;  5EG2 A;  1PEG A;  3F9Y A;  5TTF A;  3DB5 A;  3RAY A;  3S7F A;  5KJK A;  5LSX A;  3S8P A;  3N71 A;  5CPR B;  3OXL A;  4YNM A;  3M59 A;  4O30 A;  3EP0 A;  5EX0 A;  3M53 A;  4H12 A;  1ML9 A;  4J7I A;  2R3A A;  3KMA A;  5KJL A;  4BUP A;  5JHN A;  4RZ0 A;  5JIY A;  2G46 A;  4LDG A;  3VV0 A;  4QEO A;  4NJ5 A; 
#chains in the Genus database with same CATH topology
 5T0K A;  5HI7 A;  4JDS A;  2F69 A;  3OXF A;  4J83 A;  3DAL A;  3F9W A;  4Z4P A;  3RU0 A;  3M54 A;  3KMT A;  5F6K C;  5TEG A;  5TH7 A;  5JIN A;  5KJN A;  3RQ4 A;  3OS5 A;  1N6C A;  3SW9 A;  3M5A A;  4MI5 A;  5CCL A;  3M57 A;  3BO5 A;  1MVX A;  1N6A A;  3OXG A;  3HNA A;  4IJ8 A;  3MO0 A;  3S7D A;  3M58 A;  4FMU A;  3S7B A;  3CBO A;  4YND A;  3TG5 A;  3MEK A;  3S7J A;  3PDN A;  4YPE A;  5HQ8 A;  5ARG A;  2O8J A;  4I51 A;  4IJD A;  3RJW A;  3SWC A;  3K5K A;  5EX3 A;  1MUF A;  2W5Z A;  3CBP A;  3OPE A;  5F59 A;  5T0M A;  3IHX A;  4C1Q A;  3FPD A;  4YPU A;  3KMJ A;  4YNP A;  4J8O A;  1ZKK A;  4JLG A;  3MO5 A;  3QWV A;  5JJ0 A;  3M56 A;  1N3J A;  1O9S A;  1MT6 A;  4J7F A;  5T5G A;  3QWW A;  4AU7 A;  4NVQ A;  3F9Z A;  4O6F A;  3VUZ A;  5KJM A;  5AYF A;  4WUY A;  4YPA A;  3MO2 A;  3QWP A;  2BQZ A;  5ARF A;  3CBM A;  5F5E A;  3F9X A;  4QEN A;  5CCM A;  2JV0 A;  3RIB A;  2RFI A;  3OOI A;  3TG4 A;  2IGQ A;  5F6L A;  4E47 A;  1MVH A;  1H3I A;  4MI0 A;  2QPW A;  3M55 A;  2W5Y A;  5LSZ A;  4QEP A;  1XQH A;  5EG2 A;  1PEG A;  3F9Y A;  5TTF A;  3DB5 A;  3RAY A;  3S7F A;  5KJK A;  5LSX A;  3S8P A;  3N71 A;  5CPR B;  3OXL A;  4YNM A;  3M59 A;  4O30 A;  3EP0 A;  5EX0 A;  3M53 A;  4H12 A;  1ML9 A;  4J7I A;  2R3A A;  3KMA A;  5KJL A;  4BUP A;  5JHN A;  4RZ0 A;  5JIY A;  2G46 A;  4LDG A;  3VV0 A;  4QEO A;  4NJ5 A; 
#chains in the Genus database with same CATH homology
 5T0K A;  5HI7 A;  4JDS A;  2F69 A;  3OXF A;  4J83 A;  3DAL A;  3F9W A;  4Z4P A;  3RU0 A;  3M54 A;  3KMT A;  5F6K C;  5TEG A;  5TH7 A;  5JIN A;  5KJN A;  3RQ4 A;  3OS5 A;  1N6C A;  3SW9 A;  3M5A A;  4MI5 A;  5CCL A;  3M57 A;  3BO5 A;  1MVX A;  1N6A A;  3OXG A;  3HNA A;  4IJ8 A;  3MO0 A;  3S7D A;  3M58 A;  4FMU A;  3S7B A;  3CBO A;  4YND A;  3TG5 A;  3MEK A;  3S7J A;  3PDN A;  4YPE A;  5HQ8 A;  5ARG A;  2O8J A;  4I51 A;  4IJD A;  3RJW A;  3SWC A;  3K5K A;  5EX3 A;  1MUF A;  2W5Z A;  3CBP A;  3OPE A;  5F59 A;  5T0M A;  3IHX A;  4C1Q A;  3FPD A;  4YPU A;  3KMJ A;  4YNP A;  4J8O A;  1ZKK A;  4JLG A;  3MO5 A;  3QWV A;  5JJ0 A;  3M56 A;  1N3J A;  1O9S A;  1MT6 A;  4J7F A;  5T5G A;  3QWW A;  4AU7 A;  4NVQ A;  3F9Z A;  4O6F A;  3VUZ A;  5KJM A;  5AYF A;  4WUY A;  4YPA A;  3MO2 A;  3QWP A;  2BQZ A;  5ARF A;  3CBM A;  5F5E A;  3F9X A;  4QEN A;  5CCM A;  2JV0 A;  3RIB A;  2RFI A;  3OOI A;  3TG4 A;  2IGQ A;  5F6L A;  4E47 A;  1MVH A;  1H3I A;  4MI0 A;  2QPW A;  3M55 A;  2W5Y A;  5LSZ A;  4QEP A;  1XQH A;  5EG2 A;  1PEG A;  3F9Y A;  5TTF A;  3DB5 A;  3RAY A;  3S7F A;  5KJK A;  5LSX A;  3S8P A;  3N71 A;  5CPR B;  3OXL A;  4YNM A;  3M59 A;  4O30 A;  3EP0 A;  5EX0 A;  3M53 A;  4H12 A;  1ML9 A;  4J7I A;  2R3A A;  3KMA A;  5KJL A;  4BUP A;  5JHN A;  4RZ0 A;  5JIY A;  2G46 A;  4LDG A;  3VV0 A;  4QEO A;  4NJ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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