4IJ8A

Crystal structure of the complex of setd8 with sam
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
161
structure length
161
Chain Sequence
RKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKSGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the complex of SETD8 with SAM
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords N-lysine methyltransferase SETD8
total genus 44
structure length 161
sequence length 161
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2012-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 4ij8A00
4YNMA 1ML9A 1MUFA 3OS5A 5EG2A 3M58A 2W5ZA 3OXFA 5KJKA 5T0MA 1H3IA 1PEGA 3VV0A 3DALA 2BQZA 3S7FA 2IGQA 5F6LA 5KJMA 4NJ5A 5AYFA 5ARFA 2JV0A 4O30A 3QWWA 3OPEA 4JDSA 4C1QA 1XQHA 2W5YA 5KJLA 2G46A 1N6CA 5TTFA 3TG4A 4YNDA 1ZKKA 5EX3A 4IJDA 3CBMA 4RZ0A 4YPEA 3HNAA 3S8PA 4MI0A 3TG5A 5LSZA 5HI7A 5JJ0A 3KMJA 3S7DA 3OXLA 3OXGA 4O6FA 3VUZA 4QEOA 3RU0A 3CBPA 4J83A 1N3JA 4J7IA 5F5EA 4MI5A 3QWVA 4YPUA 5CCMA 5JINA 4WUYA 3OOIA 1N6AA 3EP0A 5LSXA 5T5GA 2QPWA 5JIYA 1MVXA 3SWCA 1MT6A 3QWPA 2F69A 5F6KC 4J7FA 3M53A 4I51A 3FPDA 2R3AA 4H12A 4Z4PA 3N71A 3RJWA 3MEKA 3F9ZA 3M5AA 2RFIA 3M55A 3MO2A 3M59A 4YPAA 5TEGA 3M54A 5F59A 1MVHA 4IJ8A 5T0KA 3IHXA 3F9YA 5CPRB 4QEPA 4J8OA 4NVQA 5EX0A 3M57A 3M56A 3KMTA 3PDNA 3S7BA 3K5KA 4JLGA 3RAYA 3F9WA 4E47A 5KJNA 4BUPA 3RQ4A 3BO5A 3RIBA 4QENA 5HQ8A 3CBOA 4FMUA 3MO0A 4AU7A 3F9XA 3SW9A 3DB5A 3S7JA 3KMAA 5CCLA 5JHNA 2O8JA 1O9SA 3MO5A 5ARGA 4YNPA 4LDGA 5TH7A
chains in the Genus database with same CATH superfamily
4YNMA 1ML9A 1MUFA 3OS5A 5EG2A 3M58A 2W5ZA 3OXFA 5KJKA 5T0MA 1H3IA 1PEGA 3VV0A 3DALA 2BQZA 3S7FA 2IGQA 5F6LA 5KJMA 4NJ5A 5AYFA 5ARFA 2JV0A 4O30A 3QWWA 3OPEA 4JDSA 4C1QA 1XQHA 2W5YA 5KJLA 2G46A 1N6CA 5TTFA 3TG4A 4YNDA 1ZKKA 5EX3A 4IJDA 3CBMA 4RZ0A 4YPEA 3HNAA 3S8PA 4MI0A 3TG5A 5LSZA 5HI7A 5JJ0A 3KMJA 3S7DA 3OXLA 3OXGA 4O6FA 3VUZA 4QEOA 3RU0A 3CBPA 4J83A 1N3JA 4J7IA 5F5EA 4MI5A 3QWVA 4YPUA 5CCMA 5JINA 4WUYA 3OOIA 1N6AA 3EP0A 5LSXA 5T5GA 2QPWA 5JIYA 1MVXA 3SWCA 1MT6A 3QWPA 2F69A 5F6KC 4J7FA 3M53A 4I51A 3FPDA 2R3AA 4H12A 4Z4PA 3N71A 3RJWA 3MEKA 3F9ZA 3M5AA 2RFIA 3M55A 3MO2A 3M59A 4YPAA 5TEGA 3M54A 5F59A 1MVHA 4IJ8A 5T0KA 3IHXA 3F9YA 5CPRB 4QEPA 4J8OA 4NVQA 5EX0A 3M57A 3M56A 3KMTA 3PDNA 3S7BA 3K5KA 4JLGA 3RAYA 3F9WA 4E47A 5KJNA 4BUPA 3RQ4A 3BO5A 3RIBA 4QENA 5HQ8A 3CBOA 4FMUA 3MO0A 4AU7A 3F9XA 3SW9A 3DB5A 3S7JA 3KMAA 5CCLA 5JHNA 2O8JA 1O9SA 3MO5A 5ARGA 4YNPA 4LDGA 5TH7A
chains in the Genus database with same CATH topology
4YNMA 1ML9A 1MUFA 3OS5A 5EG2A 3M58A 2W5ZA 3OXFA 5KJKA 5T0MA 1H3IA 1PEGA 3VV0A 3DALA 2BQZA 3S7FA 2IGQA 5F6LA 5KJMA 4NJ5A 5AYFA 5ARFA 2JV0A 4O30A 3QWWA 3OPEA 4JDSA 4C1QA 1XQHA 2W5YA 5KJLA 2G46A 1N6CA 5TTFA 3TG4A 4YNDA 1ZKKA 5EX3A 4IJDA 3CBMA 4RZ0A 4YPEA 3HNAA 3S8PA 4MI0A 3TG5A 5LSZA 5HI7A 5JJ0A 3KMJA 3S7DA 3OXLA 3OXGA 4O6FA 3VUZA 4QEOA 3RU0A 3CBPA 4J83A 1N3JA 4J7IA 5F5EA 4MI5A 3QWVA 4YPUA 5CCMA 5JINA 4WUYA 3OOIA 1N6AA 3EP0A 5LSXA 5T5GA 2QPWA 5JIYA 1MVXA 3SWCA 1MT6A 3QWPA 2F69A 5F6KC 4J7FA 3M53A 4I51A 3FPDA 2R3AA 4H12A 4Z4PA 3N71A 3RJWA 3MEKA 3F9ZA 3M5AA 2RFIA 3M55A 3MO2A 3M59A 4YPAA 5TEGA 3M54A 5F59A 1MVHA 4IJ8A 5T0KA 3IHXA 3F9YA 5CPRB 4QEPA 4J8OA 4NVQA 5EX0A 3M57A 3M56A 3KMTA 3PDNA 3S7BA 3K5KA 4JLGA 3RAYA 3F9WA 4E47A 5KJNA 4BUPA 3RQ4A 3BO5A 3RIBA 4QENA 5HQ8A 3CBOA 4FMUA 3MO0A 4AU7A 3F9XA 3SW9A 3DB5A 3S7JA 3KMAA 5CCLA 5JHNA 2O8JA 1O9SA 3MO5A 5ARGA 4YNPA 4LDGA 5TH7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YNM A;  1ML9 A;  1MUF A;  3OS5 A;  5EG2 A;  3M58 A;  2W5Z A;  3OXF A;  5KJK A;  5T0M A;  1H3I A;  1PEG A;  3VV0 A;  3DAL A;  2BQZ A;  3S7F A;  2IGQ A;  5F6L A;  5KJM A;  4NJ5 A;  5AYF A;  5ARF A;  2JV0 A;  4O30 A;  3QWW A;  3OPE A;  4JDS A;  4C1Q A;  1XQH A;  2W5Y A;  5KJL A;  2G46 A;  1N6C A;  5TTF A;  3TG4 A;  4YND A;  1ZKK A;  5EX3 A;  4IJD A;  3CBM A;  4RZ0 A;  4YPE A;  3HNA A;  3S8P A;  4MI0 A;  3TG5 A;  5LSZ A;  5HI7 A;  5JJ0 A;  3KMJ A;  3S7D A;  3OXL A;  3OXG A;  4O6F A;  3VUZ A;  4QEO A;  3RU0 A;  3CBP A;  4J83 A;  1N3J A;  4J7I A;  5F5E A;  4MI5 A;  3QWV A;  4YPU A;  5CCM A;  5JIN A;  4WUY A;  3OOI A;  1N6A A;  3EP0 A;  5LSX A;  5T5G A;  2QPW A;  5JIY A;  1MVX A;  3SWC A;  1MT6 A;  3QWP A;  2F69 A;  5F6K C;  4J7F A;  3M53 A;  4I51 A;  3FPD A;  2R3A A;  4H12 A;  4Z4P A;  3N71 A;  3RJW A;  3MEK A;  3F9Z A;  3M5A A;  2RFI A;  3M55 A;  3MO2 A;  3M59 A;  4YPA A;  5TEG A;  3M54 A;  5F59 A;  1MVH A;  4IJ8 A;  5T0K A;  3IHX A;  3F9Y A;  5CPR B;  4QEP A;  4J8O A;  4NVQ A;  5EX0 A;  3M57 A;  3M56 A;  3KMT A;  3PDN A;  3S7B A;  3K5K A;  4JLG A;  3RAY A;  3F9W A;  4E47 A;  5KJN A;  4BUP A;  3RQ4 A;  3BO5 A;  3RIB A;  4QEN A;  5HQ8 A;  3CBO A;  4FMU A;  3MO0 A;  4AU7 A;  3F9X A;  3SW9 A;  3DB5 A;  3S7J A;  3KMA A;  5CCL A;  5JHN A;  2O8J A;  1O9S A;  3MO5 A;  5ARG A;  4YNP A;  4LDG A;  5TH7 A; 
#chains in the Genus database with same CATH topology
 4YNM A;  1ML9 A;  1MUF A;  3OS5 A;  5EG2 A;  3M58 A;  2W5Z A;  3OXF A;  5KJK A;  5T0M A;  1H3I A;  1PEG A;  3VV0 A;  3DAL A;  2BQZ A;  3S7F A;  2IGQ A;  5F6L A;  5KJM A;  4NJ5 A;  5AYF A;  5ARF A;  2JV0 A;  4O30 A;  3QWW A;  3OPE A;  4JDS A;  4C1Q A;  1XQH A;  2W5Y A;  5KJL A;  2G46 A;  1N6C A;  5TTF A;  3TG4 A;  4YND A;  1ZKK A;  5EX3 A;  4IJD A;  3CBM A;  4RZ0 A;  4YPE A;  3HNA A;  3S8P A;  4MI0 A;  3TG5 A;  5LSZ A;  5HI7 A;  5JJ0 A;  3KMJ A;  3S7D A;  3OXL A;  3OXG A;  4O6F A;  3VUZ A;  4QEO A;  3RU0 A;  3CBP A;  4J83 A;  1N3J A;  4J7I A;  5F5E A;  4MI5 A;  3QWV A;  4YPU A;  5CCM A;  5JIN A;  4WUY A;  3OOI A;  1N6A A;  3EP0 A;  5LSX A;  5T5G A;  2QPW A;  5JIY A;  1MVX A;  3SWC A;  1MT6 A;  3QWP A;  2F69 A;  5F6K C;  4J7F A;  3M53 A;  4I51 A;  3FPD A;  2R3A A;  4H12 A;  4Z4P A;  3N71 A;  3RJW A;  3MEK A;  3F9Z A;  3M5A A;  2RFI A;  3M55 A;  3MO2 A;  3M59 A;  4YPA A;  5TEG A;  3M54 A;  5F59 A;  1MVH A;  4IJ8 A;  5T0K A;  3IHX A;  3F9Y A;  5CPR B;  4QEP A;  4J8O A;  4NVQ A;  5EX0 A;  3M57 A;  3M56 A;  3KMT A;  3PDN A;  3S7B A;  3K5K A;  4JLG A;  3RAY A;  3F9W A;  4E47 A;  5KJN A;  4BUP A;  3RQ4 A;  3BO5 A;  3RIB A;  4QEN A;  5HQ8 A;  3CBO A;  4FMU A;  3MO0 A;  4AU7 A;  3F9X A;  3SW9 A;  3DB5 A;  3S7J A;  3KMA A;  5CCL A;  5JHN A;  2O8J A;  1O9S A;  3MO5 A;  5ARG A;  4YNP A;  4LDG A;  5TH7 A; 
#chains in the Genus database with same CATH homology
 4YNM A;  1ML9 A;  1MUF A;  3OS5 A;  5EG2 A;  3M58 A;  2W5Z A;  3OXF A;  5KJK A;  5T0M A;  1H3I A;  1PEG A;  3VV0 A;  3DAL A;  2BQZ A;  3S7F A;  2IGQ A;  5F6L A;  5KJM A;  4NJ5 A;  5AYF A;  5ARF A;  2JV0 A;  4O30 A;  3QWW A;  3OPE A;  4JDS A;  4C1Q A;  1XQH A;  2W5Y A;  5KJL A;  2G46 A;  1N6C A;  5TTF A;  3TG4 A;  4YND A;  1ZKK A;  5EX3 A;  4IJD A;  3CBM A;  4RZ0 A;  4YPE A;  3HNA A;  3S8P A;  4MI0 A;  3TG5 A;  5LSZ A;  5HI7 A;  5JJ0 A;  3KMJ A;  3S7D A;  3OXL A;  3OXG A;  4O6F A;  3VUZ A;  4QEO A;  3RU0 A;  3CBP A;  4J83 A;  1N3J A;  4J7I A;  5F5E A;  4MI5 A;  3QWV A;  4YPU A;  5CCM A;  5JIN A;  4WUY A;  3OOI A;  1N6A A;  3EP0 A;  5LSX A;  5T5G A;  2QPW A;  5JIY A;  1MVX A;  3SWC A;  1MT6 A;  3QWP A;  2F69 A;  5F6K C;  4J7F A;  3M53 A;  4I51 A;  3FPD A;  2R3A A;  4H12 A;  4Z4P A;  3N71 A;  3RJW A;  3MEK A;  3F9Z A;  3M5A A;  2RFI A;  3M55 A;  3MO2 A;  3M59 A;  4YPA A;  5TEG A;  3M54 A;  5F59 A;  1MVH A;  4IJ8 A;  5T0K A;  3IHX A;  3F9Y A;  5CPR B;  4QEP A;  4J8O A;  4NVQ A;  5EX0 A;  3M57 A;  3M56 A;  3KMT A;  3PDN A;  3S7B A;  3K5K A;  4JLG A;  3RAY A;  3F9W A;  4E47 A;  5KJN A;  4BUP A;  3RQ4 A;  3BO5 A;  3RIB A;  4QEN A;  5HQ8 A;  3CBO A;  4FMU A;  3MO0 A;  4AU7 A;  3F9X A;  3SW9 A;  3DB5 A;  3S7J A;  3KMA A;  5CCL A;  5JHN A;  2O8J A;  1O9S A;  3MO5 A;  5ARG A;  4YNP A;  4LDG A;  5TH7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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