4QEPA

Crystal structure of kryptonite in complex with mchg dna and sah
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
526
structure length
467
Chain Sequence
LEPHLKVTKCLRLFNKQYLLCVQAKLSRPDLKGVTEMIKAKAILYPRKIIGDLPGIDVGHRFFSRAEMCAVGFHNHWLNGIDYMSMEYEKEYSNYKLPLAVSIVMSGQYEDDLDNADTVTYTGQGGHNLTGNKRQIKDQLLERGNLALKHCCEYNVPVRVTRGHNCKSSYTKRVYTYDGLYKVEKFWAQKGVSGFTVYKYRLKRLEGQPELTTDEGLVCEDISGGLEFKGIPATNRVDDSPVSPTSGFTYIKSLIIEPNVIIPKSSTGCNCRGSCTDSKKCACAKLNGGNFPYVDLNDGRLIESRDVVFECGPHCGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSWEYIPAGSPVCEYIGVVRRTADVNEYIFEIDCPEFCIDAGSTGNFARFINHSCEPNLFVQCVLSSHQDIRLARVVLFAADNISPMQELTYDYGYALDSVHKVKQLACYCGALNCRKRLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Arabidopsis thaliana
molecule keywords Histone-lysine N-methyltransferase, H3 lysine-9 specific SUV
total genus 118
structure length 467
sequence length 526
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2014-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02182 SAD_SRA SAD/SRA domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 4qepA03
3M56A 3S8PA 3RU0A 3DALA 4IJ8A 3RQ4A 3QWVA 3F9YA 3M57A 5JIYA 1ML9A 3S7FA 5EX0A 2QPWA 4QENA 3HNAA 1O9SA 3MEKA 4JDSA 5KJLA 2BQZA 3OS5A 1N6AA 3MO5A 3KMTA 4MI5A 5KJNA 3F9WA 1MUFA 3VUZA 5T5GA 3CBMA 3KMJA 2IGQA 4YNDA 5JINA 4YNMA 3S7DA 3S7BA 4BUPA 5LSXA 3SW9A 3TG4A 3OOIA 4O30A 4NJ5A 2O8JA 4QEOA 4C1QA 4IJDA 1MT6A 5T0KA 3F9XA 5CPRB 3M58A 3QWWA 5EX3A 4E47A 5TEGA 4MI0A 1XQHA 4NVQA 2JV0A 3RJWA 4WUYA 1N6CA 5T0MA 3FPDA 4Z4PA 4H12A 1MVHA 3IHXA 3OXLA 1ZKKA 5AYFA 5TTFA 3M54A 4J8OA 3F9ZA 1N3JA 2W5YA 4I51A 3VV0A 5KJMA 2F69A 3K5KA 3RIBA 4YPAA 5CCMA 2R3AA 2G46A 4J83A 3EP0A 1H3IA 3M53A 3M55A 3M59A 3CBPA 3S7JA 5HI7A 5JHNA 1PEGA 3OPEA 4YNPA 4JLGA 4J7FA 3BO5A 3OXFA 5JJ0A 4O6FA 3DB5A 5F5EA 3PDNA 4FMUA 5ARFA 3RAYA 3SWCA 5F59A 5ARGA 4RZ0A 3N71A 5F6KC 5EG2A 4YPEA 3CBOA 2RFIA 3M5AA 3MO2A 3TG5A 5F6LA 5CCLA 2W5ZA 5LSZA 5HQ8A 4LDGA 4AU7A 3MO0A 3KMAA 4QEPA 4YPUA 1MVXA 3QWPA 5TH7A 4J7IA 3OXGA 5KJKA
chains in the Genus database with same CATH superfamily
3M56A 3S8PA 3RU0A 3DALA 4IJ8A 3RQ4A 3QWVA 3F9YA 3M57A 5JIYA 1ML9A 3S7FA 5EX0A 2QPWA 4QENA 3HNAA 1O9SA 3MEKA 4JDSA 5KJLA 2BQZA 3OS5A 1N6AA 3MO5A 3KMTA 4MI5A 5KJNA 3F9WA 1MUFA 3VUZA 5T5GA 3CBMA 3KMJA 2IGQA 4YNDA 5JINA 4YNMA 3S7DA 3S7BA 4BUPA 5LSXA 3SW9A 3TG4A 3OOIA 4O30A 4NJ5A 2O8JA 4QEOA 4C1QA 4IJDA 1MT6A 5T0KA 3F9XA 5CPRB 3M58A 3QWWA 5EX3A 4E47A 5TEGA 4MI0A 1XQHA 4NVQA 2JV0A 3RJWA 4WUYA 1N6CA 5T0MA 3FPDA 4Z4PA 4H12A 1MVHA 3IHXA 3OXLA 1ZKKA 5AYFA 5TTFA 3M54A 4J8OA 3F9ZA 1N3JA 2W5YA 4I51A 3VV0A 5KJMA 2F69A 3K5KA 3RIBA 4YPAA 5CCMA 2R3AA 2G46A 4J83A 3EP0A 1H3IA 3M53A 3M55A 3M59A 3CBPA 3S7JA 5HI7A 5JHNA 1PEGA 3OPEA 4YNPA 4JLGA 4J7FA 3BO5A 3OXFA 5JJ0A 4O6FA 3DB5A 5F5EA 3PDNA 4FMUA 5ARFA 3RAYA 3SWCA 5F59A 5ARGA 4RZ0A 3N71A 5F6KC 5EG2A 4YPEA 3CBOA 2RFIA 3M5AA 3MO2A 3TG5A 5F6LA 5CCLA 2W5ZA 5LSZA 5HQ8A 4LDGA 4AU7A 3MO0A 3KMAA 4QEPA 4YPUA 1MVXA 3QWPA 5TH7A 4J7IA 3OXGA 5KJKA
chains in the Genus database with same CATH topology
3M56A 3S8PA 3RU0A 3DALA 4IJ8A 3RQ4A 3QWVA 3F9YA 3M57A 5JIYA 1ML9A 3S7FA 5EX0A 2QPWA 4QENA 3HNAA 1O9SA 3MEKA 4JDSA 5KJLA 2BQZA 3OS5A 1N6AA 3MO5A 3KMTA 4MI5A 5KJNA 3F9WA 1MUFA 3VUZA 5T5GA 3CBMA 3KMJA 2IGQA 4YNDA 5JINA 4YNMA 3S7DA 3S7BA 4BUPA 5LSXA 3SW9A 3TG4A 3OOIA 4O30A 4NJ5A 2O8JA 4QEOA 4C1QA 4IJDA 1MT6A 5T0KA 3F9XA 5CPRB 3M58A 3QWWA 5EX3A 4E47A 5TEGA 4MI0A 1XQHA 4NVQA 2JV0A 3RJWA 4WUYA 1N6CA 5T0MA 3FPDA 4Z4PA 4H12A 1MVHA 3IHXA 3OXLA 1ZKKA 5AYFA 5TTFA 3M54A 4J8OA 3F9ZA 1N3JA 2W5YA 4I51A 3VV0A 5KJMA 2F69A 3K5KA 3RIBA 4YPAA 5CCMA 2R3AA 2G46A 4J83A 3EP0A 1H3IA 3M53A 3M55A 3M59A 3CBPA 3S7JA 5HI7A 5JHNA 1PEGA 3OPEA 4YNPA 4JLGA 4J7FA 3BO5A 3OXFA 5JJ0A 4O6FA 3DB5A 5F5EA 3PDNA 4FMUA 5ARFA 3RAYA 3SWCA 5F59A 5ARGA 4RZ0A 3N71A 5F6KC 5EG2A 4YPEA 3CBOA 2RFIA 3M5AA 3MO2A 3TG5A 5F6LA 5CCLA 2W5ZA 5LSZA 5HQ8A 4LDGA 4AU7A 3MO0A 3KMAA 4QEPA 4YPUA 1MVXA 3QWPA 5TH7A 4J7IA 3OXGA 5KJKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M56 A;  3S8P A;  3RU0 A;  3DAL A;  4IJ8 A;  3RQ4 A;  3QWV A;  3F9Y A;  3M57 A;  5JIY A;  1ML9 A;  3S7F A;  5EX0 A;  2QPW A;  4QEN A;  3HNA A;  1O9S A;  3MEK A;  4JDS A;  5KJL A;  2BQZ A;  3OS5 A;  1N6A A;  3MO5 A;  3KMT A;  4MI5 A;  5KJN A;  3F9W A;  1MUF A;  3VUZ A;  5T5G A;  3CBM A;  3KMJ A;  2IGQ A;  4YND A;  5JIN A;  4YNM A;  3S7D A;  3S7B A;  4BUP A;  5LSX A;  3SW9 A;  3TG4 A;  3OOI A;  4O30 A;  4NJ5 A;  2O8J A;  4QEO A;  4C1Q A;  4IJD A;  1MT6 A;  5T0K A;  3F9X A;  5CPR B;  3M58 A;  3QWW A;  5EX3 A;  4E47 A;  5TEG A;  4MI0 A;  1XQH A;  4NVQ A;  2JV0 A;  3RJW A;  4WUY A;  1N6C A;  5T0M A;  3FPD A;  4Z4P A;  4H12 A;  1MVH A;  3IHX A;  3OXL A;  1ZKK A;  5AYF A;  5TTF A;  3M54 A;  4J8O A;  3F9Z A;  1N3J A;  2W5Y A;  4I51 A;  3VV0 A;  5KJM A;  2F69 A;  3K5K A;  3RIB A;  4YPA A;  5CCM A;  2R3A A;  2G46 A;  4J83 A;  3EP0 A;  1H3I A;  3M53 A;  3M55 A;  3M59 A;  3CBP A;  3S7J A;  5HI7 A;  5JHN A;  1PEG A;  3OPE A;  4YNP A;  4JLG A;  4J7F A;  3BO5 A;  3OXF A;  5JJ0 A;  4O6F A;  3DB5 A;  5F5E A;  3PDN A;  4FMU A;  5ARF A;  3RAY A;  3SWC A;  5F59 A;  5ARG A;  4RZ0 A;  3N71 A;  5F6K C;  5EG2 A;  4YPE A;  3CBO A;  2RFI A;  3M5A A;  3MO2 A;  3TG5 A;  5F6L A;  5CCL A;  2W5Z A;  5LSZ A;  5HQ8 A;  4LDG A;  4AU7 A;  3MO0 A;  3KMA A;  4QEP A;  4YPU A;  1MVX A;  3QWP A;  5TH7 A;  4J7I A;  3OXG A;  5KJK A; 
#chains in the Genus database with same CATH topology
 3M56 A;  3S8P A;  3RU0 A;  3DAL A;  4IJ8 A;  3RQ4 A;  3QWV A;  3F9Y A;  3M57 A;  5JIY A;  1ML9 A;  3S7F A;  5EX0 A;  2QPW A;  4QEN A;  3HNA A;  1O9S A;  3MEK A;  4JDS A;  5KJL A;  2BQZ A;  3OS5 A;  1N6A A;  3MO5 A;  3KMT A;  4MI5 A;  5KJN A;  3F9W A;  1MUF A;  3VUZ A;  5T5G A;  3CBM A;  3KMJ A;  2IGQ A;  4YND A;  5JIN A;  4YNM A;  3S7D A;  3S7B A;  4BUP A;  5LSX A;  3SW9 A;  3TG4 A;  3OOI A;  4O30 A;  4NJ5 A;  2O8J A;  4QEO A;  4C1Q A;  4IJD A;  1MT6 A;  5T0K A;  3F9X A;  5CPR B;  3M58 A;  3QWW A;  5EX3 A;  4E47 A;  5TEG A;  4MI0 A;  1XQH A;  4NVQ A;  2JV0 A;  3RJW A;  4WUY A;  1N6C A;  5T0M A;  3FPD A;  4Z4P A;  4H12 A;  1MVH A;  3IHX A;  3OXL A;  1ZKK A;  5AYF A;  5TTF A;  3M54 A;  4J8O A;  3F9Z A;  1N3J A;  2W5Y A;  4I51 A;  3VV0 A;  5KJM A;  2F69 A;  3K5K A;  3RIB A;  4YPA A;  5CCM A;  2R3A A;  2G46 A;  4J83 A;  3EP0 A;  1H3I A;  3M53 A;  3M55 A;  3M59 A;  3CBP A;  3S7J A;  5HI7 A;  5JHN A;  1PEG A;  3OPE A;  4YNP A;  4JLG A;  4J7F A;  3BO5 A;  3OXF A;  5JJ0 A;  4O6F A;  3DB5 A;  5F5E A;  3PDN A;  4FMU A;  5ARF A;  3RAY A;  3SWC A;  5F59 A;  5ARG A;  4RZ0 A;  3N71 A;  5F6K C;  5EG2 A;  4YPE A;  3CBO A;  2RFI A;  3M5A A;  3MO2 A;  3TG5 A;  5F6L A;  5CCL A;  2W5Z A;  5LSZ A;  5HQ8 A;  4LDG A;  4AU7 A;  3MO0 A;  3KMA A;  4QEP A;  4YPU A;  1MVX A;  3QWP A;  5TH7 A;  4J7I A;  3OXG A;  5KJK A; 
#chains in the Genus database with same CATH homology
 3M56 A;  3S8P A;  3RU0 A;  3DAL A;  4IJ8 A;  3RQ4 A;  3QWV A;  3F9Y A;  3M57 A;  5JIY A;  1ML9 A;  3S7F A;  5EX0 A;  2QPW A;  4QEN A;  3HNA A;  1O9S A;  3MEK A;  4JDS A;  5KJL A;  2BQZ A;  3OS5 A;  1N6A A;  3MO5 A;  3KMT A;  4MI5 A;  5KJN A;  3F9W A;  1MUF A;  3VUZ A;  5T5G A;  3CBM A;  3KMJ A;  2IGQ A;  4YND A;  5JIN A;  4YNM A;  3S7D A;  3S7B A;  4BUP A;  5LSX A;  3SW9 A;  3TG4 A;  3OOI A;  4O30 A;  4NJ5 A;  2O8J A;  4QEO A;  4C1Q A;  4IJD A;  1MT6 A;  5T0K A;  3F9X A;  5CPR B;  3M58 A;  3QWW A;  5EX3 A;  4E47 A;  5TEG A;  4MI0 A;  1XQH A;  4NVQ A;  2JV0 A;  3RJW A;  4WUY A;  1N6C A;  5T0M A;  3FPD A;  4Z4P A;  4H12 A;  1MVH A;  3IHX A;  3OXL A;  1ZKK A;  5AYF A;  5TTF A;  3M54 A;  4J8O A;  3F9Z A;  1N3J A;  2W5Y A;  4I51 A;  3VV0 A;  5KJM A;  2F69 A;  3K5K A;  3RIB A;  4YPA A;  5CCM A;  2R3A A;  2G46 A;  4J83 A;  3EP0 A;  1H3I A;  3M53 A;  3M55 A;  3M59 A;  3CBP A;  3S7J A;  5HI7 A;  5JHN A;  1PEG A;  3OPE A;  4YNP A;  4JLG A;  4J7F A;  3BO5 A;  3OXF A;  5JJ0 A;  4O6F A;  3DB5 A;  5F5E A;  3PDN A;  4FMU A;  5ARF A;  3RAY A;  3SWC A;  5F59 A;  5ARG A;  4RZ0 A;  3N71 A;  5F6K C;  5EG2 A;  4YPE A;  3CBO A;  2RFI A;  3M5A A;  3MO2 A;  3TG5 A;  5F6L A;  5CCL A;  2W5Z A;  5LSZ A;  5HQ8 A;  4LDG A;  4AU7 A;  3MO0 A;  3KMA A;  4QEP A;  4YPU A;  1MVX A;  3QWP A;  5TH7 A;  4J7I A;  3OXG A;  5KJK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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