4J7GA

Crystal structure of evaa, a 2,3-dehydratase in complex with dtdp-fucose and dtdp-rhamnose
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
458
structure length
448
Chain Sequence
AVRPRDHHDYADRIALSAATTDGVQMRTEDVRAWIAERRDANVFHVERIPFADLDQWWFEGVTGNLVHRSGRFFTIEGLHVIEHDGPHGDGPYREWQQPVIRQPEVGILGILAKEFDGVLHFLMQAKMEPGNPNLVQLSPTVQATRSNYTNVKLIEYFAPPDPERVIVDVLQAEQGSWFFRKSNRNMIVETVDDVPLWDDFCWLTLGQIAELMHEDETINMNSRSVLSCLPYQDITPRALFSDVQLLSWFTNERSRHDVRVRRIPLADVCGWKQGAEEIEHEDGRYFKVLAVAVKGSISWTQPLVESVDLGVVAFLVRKIDGVPHVLVQARVDGGFLDTVELAPTVQCTPLNYAHLPAEEAPPFLDLVQNAPRSRIRYEAIHSEEGGRFLGVRARYLVIDADEAIDPPPGYAWVTPAQLTALTRHGHYVNVEARTLLACINAAAAQPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Amycolatopsis orientalis
molecule keywords EvaA 2,3-dehydratase
total genus 135
structure length 448
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.2.1.159: dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase.
pdb deposition date 2013-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03559 Hexose_dehydrat NDP-hexose 2,3-dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.79.40 Alpha Beta Alpha-Beta Complex Nucleoside Triphosphate Pyrophosphohydrolase Nucleoside Triphosphate Pyrophosphohydrolase 4j7gA02
4J7HA 4J7GA
chains in the Genus database with same CATH superfamily
4MPOA 4N1TA 1KTGA 2PNYA 3HYQA 3X0SA 1NFSA 3FJYA 3Q91A 2FMLA 2YVPA 1V8VA 1Q33A 1MR2A 2FKBA 2RRKA 3DKUA 3OGAA 5CFJA 2AZWA 1SZ3A 2R5WA 3O52A 3GZ5A 2B06A 3GWYA 3L85A 4JZTA 5C7QA 3X0QA 1V8RA 2QKMB 3ID9A 5DD4A 5FSLA 3Q4IA 1JKNA 3E57A 3O8SA 3N77A 4KTBA 3CNGA 5BS6A 2YVOA 1V8LA 3QSJA 2CZRA 1VRLA 1PPWA 2PQVA 3ACAA 2A8RA 2QJTA 3O69A 4YPRA 5ANSA 2I8TA 2GT4A 2O5WA 2Q9PA 3G0QA 4DYWA 2GT2A 3SONA 2JVBA 3R03A 3BM4A 1SOIA 1G9QA 5HZXA 1JRKA 1TUMA 4JZVA 3P6YA 2I6KA 2G73A 1RRSA 1HX3A 1OW2A 2YYHA 3X0IA 4YPHA 1RYAA 3MDIA 4S2WA 3F6AA 1V8YA 2CL3A 1VHGA 1XSAA 5FSOA 3EXQA 3GRNA 5ANWA 1V8UA 3ZR1A 3A6VA 2J8QA 1GA7A 3N9UA 5DDGA 2DUKA 1Q27A 2O5FA 3AC9A 3Q93A 1PUSA 2DSCA 3DUPA 3FSPA 1IRYA 1V8IA 1QVJA 3FFUA 5C8LA 3HHJA 5LPGA 1MQWA 3SMDA 4JZUA 1VC9A 5ANUA 1VIUA 1NFZA 1KT9A 2YVMA 5FSMA 2DHOA 3Q1PA 5GHJA 5FSNA 3X0RA 5DPKA 3X0OA 1G0SA 1XSBA 3I9XA 2VNPA 5GHOA 4N1UA 2QJOA 3FCMA 3EEUA 4KG4A 1NQYA 5IW5A 3A6UA 3X0JA 1K26A 2DSBA 3X0KA 1F3YA 1VHZA 3MDGA 4KG3A 2VNQA 5C7TA 5FSIA 3GZ6A 5ANVA 1PPVA 3GZ8A 4KYXA 2A8TA 4ICKA 4ILQA 5GHMA 4C9WA 3EF5A 2GB5A 3P5TA 2ICJA 1MUTA 3I7UA 4K6EA 5GHNA 1MQEA 1PUNA 1V8WA 4J7GA 3I7VA 1U20A 5I8UA 1V8MA 4JZSA 2DSDA 2B0VA 3MGMA 5GHIA 5IW4A 5ANTA 4NFXA 3X0LA 2KDWA 4HFQA 4J7HA 3RH7A 2G74A 3COUA 3H95A 2A6TA 3FK9A 1Q54A 3GG6A 3O61A 3ZR0A 4HVYA 2XSQA 5GHPA 4NFWA 3O6ZA 3X0PA 5CFIA 2A8SA 1KHZA 3U53A 1VCDA 1PVFA 3Q2SA 4S2XA 1PPXA 1VC8A 3BHOA 4S2VA 1R67A 1HZTA 1MP2A 1X51A 1X84A 1PUQA 2B2KA 1XSCA 2FVVA 1MK1A 2A8PA 3F13A 5DEQA 5GHQA 3WHWA 3X0MA 4C9XA 3J7Ye 3SHDA 4V14A 2W4EA 1X83A 3X0NA 3EESA 3Q2TA 4ZG0A 4YOQA 3MCFA 3A6SA 1V8NA 3KVHA 2ICKA 1RRQA 4S2YA 3BAPA 2I8UA 1V8SA 2KDVA 2YVNA 3A6TA 5ISYA 1K2EA 1SJYA 2A8QA 2O1CA 1VIQA 1V8TA 1NQZA 4IJXA 1VK6A 1I9AA 1SU2A 5FSKA 5BONA
chains in the Genus database with same CATH topology
4MPOA 4N1TA 1KTGA 2PNYA 3HYQA 3X0SA 1NFSA 3FJYA 3Q91A 2FMLA 2YVPA 1V8VA 1Q33A 1MR2A 2FKBA 2RRKA 3DKUA 3OGAA 5CFJA 2AZWA 1SZ3A 2R5WA 3O52A 3GZ5A 2B06A 3GWYA 3L85A 4JZTA 5C7QA 3X0QA 1V8RA 2QKMB 3ID9A 5DD4A 5FSLA 3Q4IA 1JKNA 3E57A 3O8SA 3N77A 4KTBA 3CNGA 5BS6A 2YVOA 1V8LA 3QSJA 2CZRA 1VRLA 1PPWA 2PQVA 3ACAA 2A8RA 2QJTA 3O69A 4YPRA 5ANSA 2I8TA 2GT4A 2O5WA 2Q9PA 3G0QA 4DYWA 2GT2A 3SONA 2JVBA 3R03A 3BM4A 1SOIA 1G9QA 5HZXA 1JRKA 1TUMA 4JZVA 3P6YA 2I6KA 2G73A 1RRSA 1HX3A 1OW2A 2YYHA 3X0IA 4YPHA 1RYAA 3MDIA 4S2WA 3F6AA 1V8YA 2CL3A 1VHGA 1XSAA 5FSOA 3EXQA 3GRNA 5ANWA 1V8UA 3ZR1A 3A6VA 2J8QA 1GA7A 3N9UA 5DDGA 2DUKA 1Q27A 2O5FA 3AC9A 3Q93A 1PUSA 2DSCA 3DUPA 3FSPA 1IRYA 1V8IA 1QVJA 3FFUA 5C8LA 3HHJA 5LPGA 1MQWA 3SMDA 4JZUA 1VC9A 5ANUA 1VIUA 1NFZA 1KT9A 2YVMA 5FSMA 2DHOA 3Q1PA 5GHJA 5FSNA 3X0RA 5DPKA 3X0OA 1G0SA 1XSBA 3I9XA 2VNPA 5GHOA 4N1UA 2QJOA 3FCMA 3EEUA 4KG4A 1NQYA 5IW5A 3A6UA 3X0JA 1K26A 2DSBA 3X0KA 1F3YA 1VHZA 3MDGA 4KG3A 2VNQA 5C7TA 5FSIA 3GZ6A 5ANVA 1PPVA 3GZ8A 4KYXA 2A8TA 4ICKA 4ILQA 5GHMA 4C9WA 3EF5A 2GB5A 3P5TA 2ICJA 1MUTA 3I7UA 4K6EA 5GHNA 1MQEA 1PUNA 1V8WA 4J7GA 3I7VA 1U20A 5I8UA 1V8MA 4JZSA 2DSDA 2B0VA 3MGMA 5GHIA 5IW4A 5ANTA 4NFXA 3X0LA 2KDWA 4HFQA 4J7HA 3RH7A 2G74A 3COUA 3H95A 2A6TA 3FK9A 1Q54A 3GG6A 3O61A 3ZR0A 4HVYA 2XSQA 5GHPA 4NFWA 3O6ZA 3X0PA 5CFIA 2A8SA 1KHZA 3U53A 1VCDA 1PVFA 3Q2SA 4S2XA 1PPXA 1VC8A 3BHOA 4S2VA 1R67A 1HZTA 1MP2A 1X51A 1X84A 1PUQA 2B2KA 1XSCA 2FVVA 1MK1A 2A8PA 3F13A 5DEQA 5GHQA 3WHWA 3X0MA 4C9XA 3J7Ye 3SHDA 4V14A 2W4EA 1X83A 3X0NA 3EESA 3Q2TA 4ZG0A 4YOQA 3MCFA 3A6SA 1V8NA 3KVHA 2ICKA 1RRQA 4S2YA 3BAPA 2I8UA 1V8SA 2KDVA 2YVNA 3A6TA 5ISYA 1K2EA 1SJYA 2A8QA 2O1CA 1VIQA 1V8TA 1NQZA 4IJXA 1VK6A 1I9AA 1SU2A 5FSKA 5BONA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J7H A;  4J7G A; 
#chains in the Genus database with same CATH topology
 4MPO A;  4N1T A;  1KTG A;  2PNY A;  3HYQ A;  3X0S A;  1NFS A;  3FJY A;  3Q91 A;  2FML A;  2YVP A;  1V8V A;  1Q33 A;  1MR2 A;  2FKB A;  2RRK A;  3DKU A;  3OGA A;  5CFJ A;  2AZW A;  1SZ3 A;  2R5W A;  3O52 A;  3GZ5 A;  2B06 A;  3GWY A;  3L85 A;  4JZT A;  5C7Q A;  3X0Q A;  1V8R A;  2QKM B;  3ID9 A;  5DD4 A;  5FSL A;  3Q4I A;  1JKN A;  3E57 A;  3O8S A;  3N77 A;  4KTB A;  3CNG A;  5BS6 A;  2YVO A;  1V8L A;  3QSJ A;  2CZR A;  1VRL A;  1PPW A;  2PQV A;  3ACA A;  2A8R A;  2QJT A;  3O69 A;  4YPR A;  5ANS A;  2I8T A;  2GT4 A;  2O5W A;  2Q9P A;  3G0Q A;  4DYW A;  2GT2 A;  3SON A;  2JVB A;  3R03 A;  3BM4 A;  1SOI A;  1G9Q A;  5HZX A;  1JRK A;  1TUM A;  4JZV A;  3P6Y A;  2I6K A;  2G73 A;  1RRS A;  1HX3 A;  1OW2 A;  2YYH A;  3X0I A;  4YPH A;  1RYA A;  3MDI A;  4S2W A;  3F6A A;  1V8Y A;  2CL3 A;  1VHG A;  1XSA A;  5FSO A;  3EXQ A;  3GRN A;  5ANW A;  1V8U A;  3ZR1 A;  3A6V A;  2J8Q A;  1GA7 A;  3N9U A;  5DDG A;  2DUK A;  1Q27 A;  2O5F A;  3AC9 A;  3Q93 A;  1PUS A;  2DSC A;  3DUP A;  3FSP A;  1IRY A;  1V8I A;  1QVJ A;  3FFU A;  5C8L A;  3HHJ A;  5LPG A;  1MQW A;  3SMD A;  4JZU A;  1VC9 A;  5ANU A;  1VIU A;  1NFZ A;  1KT9 A;  2YVM A;  5FSM A;  2DHO A;  3Q1P A;  5GHJ A;  5FSN A;  3X0R A;  5DPK A;  3X0O A;  1G0S A;  1XSB A;  3I9X A;  2VNP A;  5GHO A;  4N1U A;  2QJO A;  3FCM A;  3EEU A;  4KG4 A;  1NQY A;  5IW5 A;  3A6U A;  3X0J A;  1K26 A;  2DSB A;  3X0K A;  1F3Y A;  1VHZ A;  3MDG A;  4KG3 A;  2VNQ A;  5C7T A;  5FSI A;  3GZ6 A;  5ANV A;  1PPV A;  3GZ8 A;  4KYX A;  2A8T A;  4ICK A;  4ILQ A;  5GHM A;  4C9W A;  3EF5 A;  2GB5 A;  3P5T A;  2ICJ A;  1MUT A;  3I7U A;  4K6E A;  5GHN A;  1MQE A;  1PUN A;  1V8W A;  4J7G A;  3I7V A;  1U20 A;  5I8U A;  1V8M A;  4JZS A;  2DSD A;  2B0V A;  3MGM A;  5GHI A;  5IW4 A;  5ANT A;  4NFX A;  3X0L A;  2KDW A;  4HFQ A;  4J7H A;  3RH7 A;  2G74 A;  3COU A;  3H95 A;  2A6T A;  3FK9 A;  1Q54 A;  3GG6 A;  3O61 A;  3ZR0 A;  4HVY A;  2XSQ A;  5GHP A;  4NFW A;  3O6Z A;  3X0P A;  5CFI A;  2A8S A;  1KHZ A;  3U53 A;  1VCD A;  1PVF A;  3Q2S A;  4S2X A;  1PPX A;  1VC8 A;  3BHO A;  4S2V A;  1R67 A;  1HZT A;  1MP2 A;  1X51 A;  1X84 A;  1PUQ A;  2B2K A;  1XSC A;  2FVV A;  1MK1 A;  2A8P A;  3F13 A;  5DEQ A;  5GHQ A;  3WHW A;  3X0M A;  4C9X A;  3J7Y e;  3SHD A;  4V14 A;  2W4E A;  1X83 A;  3X0N A;  3EES A;  3Q2T A;  4ZG0 A;  4YOQ A;  3MCF A;  3A6S A;  1V8N A;  3KVH A;  2ICK A;  1RRQ A;  4S2Y A;  3BAP A;  2I8U A;  1V8S A;  2KDV A;  2YVN A;  3A6T A;  5ISY A;  1K2E A;  1SJY A;  2A8Q A;  2O1C A;  1VIQ A;  1V8T A;  1NQZ A;  4IJX A;  1VK6 A;  1I9A A;  1SU2 A;  5FSK A;  5BON A; 
#chains in the Genus database with same CATH homology
 4MPO A;  4N1T A;  1KTG A;  2PNY A;  3HYQ A;  3X0S A;  1NFS A;  3FJY A;  3Q91 A;  2FML A;  2YVP A;  1V8V A;  1Q33 A;  1MR2 A;  2FKB A;  2RRK A;  3DKU A;  3OGA A;  5CFJ A;  2AZW A;  1SZ3 A;  2R5W A;  3O52 A;  3GZ5 A;  2B06 A;  3GWY A;  3L85 A;  4JZT A;  5C7Q A;  3X0Q A;  1V8R A;  2QKM B;  3ID9 A;  5DD4 A;  5FSL A;  3Q4I A;  1JKN A;  3E57 A;  3O8S A;  3N77 A;  4KTB A;  3CNG A;  5BS6 A;  2YVO A;  1V8L A;  3QSJ A;  2CZR A;  1VRL A;  1PPW A;  2PQV A;  3ACA A;  2A8R A;  2QJT A;  3O69 A;  4YPR A;  5ANS A;  2I8T A;  2GT4 A;  2O5W A;  2Q9P A;  3G0Q A;  4DYW A;  2GT2 A;  3SON A;  2JVB A;  3R03 A;  3BM4 A;  1SOI A;  1G9Q A;  5HZX A;  1JRK A;  1TUM A;  4JZV A;  3P6Y A;  2I6K A;  2G73 A;  1RRS A;  1HX3 A;  1OW2 A;  2YYH A;  3X0I A;  4YPH A;  1RYA A;  3MDI A;  4S2W A;  3F6A A;  1V8Y A;  2CL3 A;  1VHG A;  1XSA A;  5FSO A;  3EXQ A;  3GRN A;  5ANW A;  1V8U A;  3ZR1 A;  3A6V A;  2J8Q A;  1GA7 A;  3N9U A;  5DDG A;  2DUK A;  1Q27 A;  2O5F A;  3AC9 A;  3Q93 A;  1PUS A;  2DSC A;  3DUP A;  3FSP A;  1IRY A;  1V8I A;  1QVJ A;  3FFU A;  5C8L A;  3HHJ A;  5LPG A;  1MQW A;  3SMD A;  4JZU A;  1VC9 A;  5ANU A;  1VIU A;  1NFZ A;  1KT9 A;  2YVM A;  5FSM A;  2DHO A;  3Q1P A;  5GHJ A;  5FSN A;  3X0R A;  5DPK A;  3X0O A;  1G0S A;  1XSB A;  3I9X A;  2VNP A;  5GHO A;  4N1U A;  2QJO A;  3FCM A;  3EEU A;  4KG4 A;  1NQY A;  5IW5 A;  3A6U A;  3X0J A;  1K26 A;  2DSB A;  3X0K A;  1F3Y A;  1VHZ A;  3MDG A;  4KG3 A;  2VNQ A;  5C7T A;  5FSI A;  3GZ6 A;  5ANV A;  1PPV A;  3GZ8 A;  4KYX A;  2A8T A;  4ICK A;  4ILQ A;  5GHM A;  4C9W A;  3EF5 A;  2GB5 A;  3P5T A;  2ICJ A;  1MUT A;  3I7U A;  4K6E A;  5GHN A;  1MQE A;  1PUN A;  1V8W A;  4J7G A;  3I7V A;  1U20 A;  5I8U A;  1V8M A;  4JZS A;  2DSD A;  2B0V A;  3MGM A;  5GHI A;  5IW4 A;  5ANT A;  4NFX A;  3X0L A;  2KDW A;  4HFQ A;  4J7H A;  3RH7 A;  2G74 A;  3COU A;  3H95 A;  2A6T A;  3FK9 A;  1Q54 A;  3GG6 A;  3O61 A;  3ZR0 A;  4HVY A;  2XSQ A;  5GHP A;  4NFW A;  3O6Z A;  3X0P A;  5CFI A;  2A8S A;  1KHZ A;  3U53 A;  1VCD A;  1PVF A;  3Q2S A;  4S2X A;  1PPX A;  1VC8 A;  3BHO A;  4S2V A;  1R67 A;  1HZT A;  1MP2 A;  1X51 A;  1X84 A;  1PUQ A;  2B2K A;  1XSC A;  2FVV A;  1MK1 A;  2A8P A;  3F13 A;  5DEQ A;  5GHQ A;  3WHW A;  3X0M A;  4C9X A;  3J7Y e;  3SHD A;  4V14 A;  2W4E A;  1X83 A;  3X0N A;  3EES A;  3Q2T A;  4ZG0 A;  4YOQ A;  3MCF A;  3A6S A;  1V8N A;  3KVH A;  2ICK A;  1RRQ A;  4S2Y A;  3BAP A;  2I8U A;  1V8S A;  2KDV A;  2YVN A;  3A6T A;  5ISY A;  1K2E A;  1SJY A;  2A8Q A;  2O1C A;  1VIQ A;  1V8T A;  1NQZ A;  4IJX A;  1VK6 A;  1I9A A;  1SU2 A;  5FSK A;  5BON A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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