2BFRA

The macro domain is an adp-ribose binding module
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
191
structure length
191
Chain Sequence
EVLFEAKVGDITLKLAQGDITQYPAKAIVNAANKRLEHGGGVAYAIAKACAGDAGLYTEISKKAMREQFGRDYIDHGEVVVTPAMNLEERGIKYVFHTVGPICSGMWSEELKEKLYKAFLGPLEKAEEMGVESIAFPAVSAGIYGCDLEKVVETFLEAVKNFKGSAVKEVALVIYDRKSAEVALKVFERSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Macro Domain is an Adp-Ribose Binding Module.
pubmed doi rcsb
molecule keywords HYPOTHETICAL PROTEIN AF1521
molecule tags Macro_h2a domain/hydrolase
source organism Archaeoglobus fulgidus
total genus 68
structure length 191
sequence length 191
ec nomenclature
pdb deposition date 2004-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 2bfrA00
5AILA 3SIJA 5CB5A 4ABLA 5CBMA 4GUAA 3SIHA 3JZTA 2EEEA 2X47A 4ZI6A 3KR4A 1LANA 4R6TA 3SIGA 5DUSA 2FG1A 3KQXA 1TXZA 1LAPA 3GPGA 4R76A 3H8EA 4UMLA 4IQYA 2BFQA 4X2TA 4ZYQA 1GYTA 3V45A 3Q71A 3IIDA 4ZX8A 5FSYA 3EWRA 2AFCA 1SPVA 3H8GA 5CMSA 3VFQA 4ZY1A 4ABKA 5FSVA 3SIIA 1HJZA 3EKEA 3H8FA 4K3NA 4ESSA 3EWQA 4TU0A 4JVVA 4ETJA 1ZR3A 4D86A 3JRUA 5HOLA 1LAMA 1VHUA 4GVWA 4ZY2A 3IIFA 1BPMA 3KQZA 5FSUA 3GQEA 2DX6A 3T8WA 5E3BA 3ETIA 3KZWA 2BFRA 5FSZA 2LGRA 1ZR5A 3EWOA 4ZY0A 2ACFA 3EW5A 4JCAA 2XD7A 5CB3A 2FAVA 2VRIA 3EJGA 4GVVA 3PEIA 1BPNA 4R7MA 1YD9A 2J9AA 3KR5A 4J4ZA 4J5QA 2EWBA 3V2BA 4JGKA 4JLLA 3IJ3A 4ETKA 1BLLE 3Q6ZA 2FXKA 4KSIA 1NJRA 1TY8A 3EJFA 5FSXA 5HIHA 5D8NA 4J5RA 4K0CA 4ZX9A 1LCPA 2L8RA 3GPOA 3EWPA 4KYBA 4J5SA 3GPQA 3GQOA
chains in the Genus database with same CATH superfamily
5AILA 3SIJA 5CB5A 4ABLA 5CBMA 4GUAA 3SIHA 2KQVA 3JZTA 2EEEA 2X47A 4ZI6A 2RNKA 3KR4A 1LANA 4R6TA 3SIGA 5DUSA 2FG1A 3KQXA 1TXZA 1LAPA 3GPGA 2JZEA 4R76A 3H8EA 4UMLA 4IQYA 2BFQA 4X2TA 4ZYQA 1GYTA 3V45A 3Q71A 3IIDA 4ZX8A 5FSYA 3EWRA 2AFCA 1SPVA 3H8GA 5CMSA 3VFQA 4ZY1A 4ABKA 5FSVA 3SIIA 1HJZA 3EKEA 3H8FA 4K3NA 4ESSA 3EWQA 4TU0A 4JVVA 4ETJA 1ZR3A 4D86A 3JRUA 5HOLA 1LAMA 1VHUA 4GVWA 4ZY2A 3IIFA 2JZFA 1BPMA 3KQZA 5FSUA 3GQEA 2DX6A 3T8WA 5E3BA 3ETIA 3KZWA 2BFRA 5FSZA 2LGRA 1ZR5A 3EWOA 4ZY0A 2ACFA 3EW5A 4JCAA 2XD7A 5CB3A 2FAVA 2VRIA 3EJGA 4GVVA 3PEIA 2JZDA 1BPNA 4R7MA 1YD9A 2J9AA 3KR5A 4J4ZA 4J5QA 2WCTA 2EWBA 3V2BA 4JGKA 4JLLA 3IJ3A 4ETKA 1BLLE 3Q6ZA 2FXKA 4KSIA 1NJRA 1TY8A 3EJFA 5FSXA 5HIHA 5D8NA 4J5RA 2W2GA 4K0CA 4ZX9A 1LCPA 2L8RA 3GPOA 3EWPA 4KYBA 4J5SA 3GPQA 3GQOA
chains in the Genus database with same CATH topology
5AILA 3SIJA 5CB5A 4ABLA 5CBMA 4GUAA 3SIHA 3JZTA 2EEEA 2X47A 4ZI6A 3KR4A 1LANA 4R6TA 3SIGA 5DUSA 2FG1A 3KQXA 1TXZA 1LAPA 3GPGA 4R76A 3H8EA 4UMLA 4IQYA 2BFQA 4X2TA 4ZYQA 1GYTA 3V45A 3Q71A 3IIDA 4ZX8A 5FSYA 3EWRA 2AFCA 1SPVA 3H8GA 5CMSA 3VFQA 4ZY1A 4ABKA 5FSVA 3SIIA 1HJZA 3EKEA 3H8FA 4K3NA 4ESSA 3EWQA 4TU0A 4JVVA 4ETJA 1ZR3A 4D86A 3JRUA 5HOLA 1LAMA 1VHUA 4GVWA 4ZY2A 3IIFA 1BPMA 3KQZA 5FSUA 3GQEA 2DX6A 3T8WA 5E3BA 3ETIA 3KZWA 2BFRA 5FSZA 2LGRA 1ZR5A 3EWOA 4ZY0A 2ACFA 3EW5A 4JCAA 2XD7A 5CB3A 2FAVA 2VRIA 3EJGA 4GVVA 3PEIA 1BPNA 4R7MA 1YD9A 2J9AA 3KR5A 4J4ZA 4J5QA 2EWBA 3V2BA 4JGKA 4JLLA 3IJ3A 4ETKA 1BLLE 3Q6ZA 2FXKA 4KSIA 1NJRA 1TY8A 3EJFA 5FSXA 5HIHA 5D8NA 4J5RA 4K0CA 4ZX9A 1LCPA 2L8RA 3GPOA 3EWPA 4KYBA 4J5SA 3GPQA 3GQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AIL A;  3SIJ A;  5CB5 A;  4ABL A;  5CBM A;  4GUA A;  3SIH A;  3JZT A;  2EEE A;  2X47 A;  4ZI6 A;  3KR4 A;  1LAN A;  4R6T A;  3SIG A;  5DUS A;  2FG1 A;  3KQX A;  1TXZ A;  1LAP A;  3GPG A;  4R76 A;  3H8E A;  4UML A;  4IQY A;  2BFQ A;  4X2T A;  4ZYQ A;  1GYT A;  3V45 A;  3Q71 A;  3IID A;  4ZX8 A;  5FSY A;  3EWR A;  2AFC A;  1SPV A;  3H8G A;  5CMS A;  3VFQ A;  4ZY1 A;  4ABK A;  5FSV A;  3SII A;  1HJZ A;  3EKE A;  3H8F A;  4K3N A;  4ESS A;  3EWQ A;  4TU0 A;  4JVV A;  4ETJ A;  1ZR3 A;  4D86 A;  3JRU A;  5HOL A;  1LAM A;  1VHU A;  4GVW A;  4ZY2 A;  3IIF A;  1BPM A;  3KQZ A;  5FSU A;  3GQE A;  2DX6 A;  3T8W A;  5E3B A;  3ETI A;  3KZW A;  2BFR A;  5FSZ A;  2LGR A;  1ZR5 A;  3EWO A;  4ZY0 A;  2ACF A;  3EW5 A;  4JCA A;  2XD7 A;  5CB3 A;  2FAV A;  2VRI A;  3EJG A;  4GVV A;  3PEI A;  1BPN A;  4R7M A;  1YD9 A;  2J9A A;  3KR5 A;  4J4Z A;  4J5Q A;  2EWB A;  3V2B A;  4JGK A;  4JLL A;  3IJ3 A;  4ETK A;  1BLL E;  3Q6Z A;  2FXK A;  4KSI A;  1NJR A;  1TY8 A;  3EJF A;  5FSX A;  5HIH A;  5D8N A;  4J5R A;  4K0C A;  4ZX9 A;  1LCP A;  2L8R A;  3GPO A;  3EWP A;  4KYB A;  4J5S A;  3GPQ A;  3GQO A; 
#chains in the Genus database with same CATH topology
 5AIL A;  3SIJ A;  5CB5 A;  4ABL A;  5CBM A;  4GUA A;  3SIH A;  2KQV A;  3JZT A;  2EEE A;  2X47 A;  4ZI6 A;  2RNK A;  3KR4 A;  1LAN A;  4R6T A;  3SIG A;  5DUS A;  2FG1 A;  3KQX A;  1TXZ A;  1LAP A;  3GPG A;  2JZE A;  4R76 A;  3H8E A;  4UML A;  4IQY A;  2BFQ A;  4X2T A;  4ZYQ A;  1GYT A;  3V45 A;  3Q71 A;  3IID A;  4ZX8 A;  5FSY A;  3EWR A;  2AFC A;  1SPV A;  3H8G A;  5CMS A;  3VFQ A;  4ZY1 A;  4ABK A;  5FSV A;  3SII A;  1HJZ A;  3EKE A;  3H8F A;  4K3N A;  4ESS A;  3EWQ A;  4TU0 A;  4JVV A;  4ETJ A;  1ZR3 A;  4D86 A;  3JRU A;  5HOL A;  1LAM A;  1VHU A;  4GVW A;  4ZY2 A;  3IIF A;  2JZF A;  1BPM A;  3KQZ A;  5FSU A;  3GQE A;  2DX6 A;  3T8W A;  5E3B A;  3ETI A;  3KZW A;  2BFR A;  5FSZ A;  2LGR A;  1ZR5 A;  3EWO A;  4ZY0 A;  2ACF A;  3EW5 A;  4JCA A;  2XD7 A;  5CB3 A;  2FAV A;  2VRI A;  3EJG A;  4GVV A;  3PEI A;  2JZD A;  1BPN A;  4R7M A;  1YD9 A;  2J9A A;  3KR5 A;  4J4Z A;  4J5Q A;  2WCT A;  2EWB A;  3V2B A;  4JGK A;  4JLL A;  3IJ3 A;  4ETK A;  1BLL E;  3Q6Z A;  2FXK A;  4KSI A;  1NJR A;  1TY8 A;  3EJF A;  5FSX A;  5HIH A;  5D8N A;  4J5R A;  2W2G A;  4K0C A;  4ZX9 A;  1LCP A;  2L8R A;  3GPO A;  3EWP A;  4KYB A;  4J5S A;  3GPQ A;  3GQO A; 
#chains in the Genus database with same CATH homology
 5AIL A;  3SIJ A;  5CB5 A;  4ABL A;  5CBM A;  4GUA A;  3SIH A;  3JZT A;  2EEE A;  2X47 A;  4ZI6 A;  3KR4 A;  1LAN A;  4R6T A;  3SIG A;  5DUS A;  2FG1 A;  3KQX A;  1TXZ A;  1LAP A;  3GPG A;  4R76 A;  3H8E A;  4UML A;  4IQY A;  2BFQ A;  4X2T A;  4ZYQ A;  1GYT A;  3V45 A;  3Q71 A;  3IID A;  4ZX8 A;  5FSY A;  3EWR A;  2AFC A;  1SPV A;  3H8G A;  5CMS A;  3VFQ A;  4ZY1 A;  4ABK A;  5FSV A;  3SII A;  1HJZ A;  3EKE A;  3H8F A;  4K3N A;  4ESS A;  3EWQ A;  4TU0 A;  4JVV A;  4ETJ A;  1ZR3 A;  4D86 A;  3JRU A;  5HOL A;  1LAM A;  1VHU A;  4GVW A;  4ZY2 A;  3IIF A;  1BPM A;  3KQZ A;  5FSU A;  3GQE A;  2DX6 A;  3T8W A;  5E3B A;  3ETI A;  3KZW A;  2BFR A;  5FSZ A;  2LGR A;  1ZR5 A;  3EWO A;  4ZY0 A;  2ACF A;  3EW5 A;  4JCA A;  2XD7 A;  5CB3 A;  2FAV A;  2VRI A;  3EJG A;  4GVV A;  3PEI A;  1BPN A;  4R7M A;  1YD9 A;  2J9A A;  3KR5 A;  4J4Z A;  4J5Q A;  2EWB A;  3V2B A;  4JGK A;  4JLL A;  3IJ3 A;  4ETK A;  1BLL E;  3Q6Z A;  2FXK A;  4KSI A;  1NJR A;  1TY8 A;  3EJF A;  5FSX A;  5HIH A;  5D8N A;  4J5R A;  4K0C A;  4ZX9 A;  1LCP A;  2L8R A;  3GPO A;  3EWP A;  4KYB A;  4J5S A;  3GPQ A;  3GQO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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