5HIHA

Crystal structure of the macro domain in middle-east respiratory syndrome coronavirus
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
167
structure length
167
Chain Sequence
MDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
pubmed doi rcsb
source organism Middle east respiratory syndrome coronavirus
molecule tags Viral protein
molecule keywords ORF1a
total genus 57
structure length 167
sequence length 167
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2016-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5hihA00
2LGRA 1BLLE 1HJZA 4ZX8A 5FSUA 4ABLA 4ZI6A 4JCAA 3VFQA 4UMLA 4JLLA 3SIHA 4JGKA 3H8EA 3EWRA 5E3BA 5HOLA 1TXZA 1ZR5A 3KR4A 3JRUA 3KQZA 5CBMA 4ZYQA 3JZTA 2EWBA 1LCPA 3GPQA 3SIJA 2X47A 2J9AA 3H8FA 3EJGA 1YD9A 1LANA 1LAPA 3SIIA 2XD7A 3KR5A 2L8RA 4K3NA 2BFQA 4ETJA 3KQXA 2FXKA 2FG1A 3KZWA 3EWQA 1BPMA 5HIHA 2ACFA 4ZY1A 5D8NA 4R7MA 1SPVA 1LAMA 4ESSA 3GQOA 5FSVA 3Q71A 4GVWA 4ZY0A 4ZY2A 4X2TA 3EWPA 3ETIA 2VRIA 1NJRA 4TU0A 5CB3A 5FSYA 4ZX9A 1TY8A 3V45A 1GYTA 4JVVA 2DX6A 1VHUA 2AFCA 2EEEA 3IIFA 4J5RA 4R6TA 2FAVA 4D86A 4ETKA 4KYBA 3H8GA 1ZR3A 3EKEA 5CB5A 5FSZA 3EWOA 4IQYA 4J4ZA 3IJ3A 4K0CA 4J5QA 3GQEA 4J5SA 1BPNA 3Q6ZA 4R76A 3IIDA 5CMSA 5DUSA 3GPOA 3PEIA 3EW5A 3GPGA 2BFRA 4ABKA 3EJFA 4GUAA 5FSXA 3T8WA 3V2BA 5AILA 3SIGA 4KSIA 4GVVA
chains in the Genus database with same CATH superfamily
2LGRA 1BLLE 1HJZA 4ZX8A 5FSUA 4ABLA 4ZI6A 4JCAA 3VFQA 4UMLA 2JZFA 4JLLA 3SIHA 4JGKA 3H8EA 3EWRA 5E3BA 5HOLA 1TXZA 1ZR5A 3KR4A 3JRUA 3KQZA 5CBMA 4ZYQA 3JZTA 2EWBA 1LCPA 3GPQA 3SIJA 2X47A 2J9AA 3H8FA 3EJGA 1YD9A 2JZDA 1LANA 1LAPA 3SIIA 2XD7A 3KR5A 2L8RA 4K3NA 2BFQA 4ETJA 3KQXA 2FXKA 2FG1A 3KZWA 3EWQA 1BPMA 5HIHA 2ACFA 4ZY1A 5D8NA 4R7MA 1SPVA 1LAMA 4ESSA 3GQOA 5FSVA 3Q71A 4GVWA 4ZY0A 4ZY2A 4X2TA 3EWPA 2RNKA 3ETIA 2VRIA 1NJRA 4TU0A 5CB3A 5FSYA 4ZX9A 1TY8A 3V45A 1GYTA 4JVVA 2JZEA 2DX6A 1VHUA 2AFCA 2EEEA 3IIFA 4J5RA 4R6TA 2FAVA 4D86A 4ETKA 4KYBA 3H8GA 1ZR3A 3EKEA 5CB5A 5FSZA 3EWOA 4IQYA 4J4ZA 3IJ3A 4K0CA 4J5QA 3GQEA 2WCTA 4J5SA 1BPNA 3Q6ZA 4R76A 3IIDA 5CMSA 5DUSA 3GPOA 3PEIA 3EW5A 3GPGA 2KQVA 2BFRA 2W2GA 4ABKA 3EJFA 4GUAA 5FSXA 3T8WA 3V2BA 5AILA 3SIGA 4KSIA 4GVVA
chains in the Genus database with same CATH topology
2LGRA 1BLLE 1HJZA 4ZX8A 5FSUA 4ABLA 4ZI6A 4JCAA 3VFQA 4UMLA 4JLLA 3SIHA 4JGKA 3H8EA 3EWRA 5E3BA 5HOLA 1TXZA 1ZR5A 3KR4A 3JRUA 3KQZA 5CBMA 4ZYQA 3JZTA 2EWBA 1LCPA 3GPQA 3SIJA 2X47A 2J9AA 3H8FA 3EJGA 1YD9A 1LANA 1LAPA 3SIIA 2XD7A 3KR5A 2L8RA 4K3NA 2BFQA 4ETJA 3KQXA 2FXKA 2FG1A 3KZWA 3EWQA 1BPMA 5HIHA 2ACFA 4ZY1A 5D8NA 4R7MA 1SPVA 1LAMA 4ESSA 3GQOA 5FSVA 3Q71A 4GVWA 4ZY0A 4ZY2A 4X2TA 3EWPA 3ETIA 2VRIA 1NJRA 4TU0A 5CB3A 5FSYA 4ZX9A 1TY8A 3V45A 1GYTA 4JVVA 2DX6A 1VHUA 2AFCA 2EEEA 3IIFA 4J5RA 4R6TA 2FAVA 4D86A 4ETKA 4KYBA 3H8GA 1ZR3A 3EKEA 5CB5A 5FSZA 3EWOA 4IQYA 4J4ZA 3IJ3A 4K0CA 4J5QA 3GQEA 4J5SA 1BPNA 3Q6ZA 4R76A 3IIDA 5CMSA 5DUSA 3GPOA 3PEIA 3EW5A 3GPGA 2BFRA 4ABKA 3EJFA 4GUAA 5FSXA 3T8WA 3V2BA 5AILA 3SIGA 4KSIA 4GVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LGR A;  1BLL E;  1HJZ A;  4ZX8 A;  5FSU A;  4ABL A;  4ZI6 A;  4JCA A;  3VFQ A;  4UML A;  4JLL A;  3SIH A;  4JGK A;  3H8E A;  3EWR A;  5E3B A;  5HOL A;  1TXZ A;  1ZR5 A;  3KR4 A;  3JRU A;  3KQZ A;  5CBM A;  4ZYQ A;  3JZT A;  2EWB A;  1LCP A;  3GPQ A;  3SIJ A;  2X47 A;  2J9A A;  3H8F A;  3EJG A;  1YD9 A;  1LAN A;  1LAP A;  3SII A;  2XD7 A;  3KR5 A;  2L8R A;  4K3N A;  2BFQ A;  4ETJ A;  3KQX A;  2FXK A;  2FG1 A;  3KZW A;  3EWQ A;  1BPM A;  5HIH A;  2ACF A;  4ZY1 A;  5D8N A;  4R7M A;  1SPV A;  1LAM A;  4ESS A;  3GQO A;  5FSV A;  3Q71 A;  4GVW A;  4ZY0 A;  4ZY2 A;  4X2T A;  3EWP A;  3ETI A;  2VRI A;  1NJR A;  4TU0 A;  5CB3 A;  5FSY A;  4ZX9 A;  1TY8 A;  3V45 A;  1GYT A;  4JVV A;  2DX6 A;  1VHU A;  2AFC A;  2EEE A;  3IIF A;  4J5R A;  4R6T A;  2FAV A;  4D86 A;  4ETK A;  4KYB A;  3H8G A;  1ZR3 A;  3EKE A;  5CB5 A;  5FSZ A;  3EWO A;  4IQY A;  4J4Z A;  3IJ3 A;  4K0C A;  4J5Q A;  3GQE A;  4J5S A;  1BPN A;  3Q6Z A;  4R76 A;  3IID A;  5CMS A;  5DUS A;  3GPO A;  3PEI A;  3EW5 A;  3GPG A;  2BFR A;  4ABK A;  3EJF A;  4GUA A;  5FSX A;  3T8W A;  3V2B A;  5AIL A;  3SIG A;  4KSI A;  4GVV A; 
#chains in the Genus database with same CATH topology
 2LGR A;  1BLL E;  1HJZ A;  4ZX8 A;  5FSU A;  4ABL A;  4ZI6 A;  4JCA A;  3VFQ A;  4UML A;  2JZF A;  4JLL A;  3SIH A;  4JGK A;  3H8E A;  3EWR A;  5E3B A;  5HOL A;  1TXZ A;  1ZR5 A;  3KR4 A;  3JRU A;  3KQZ A;  5CBM A;  4ZYQ A;  3JZT A;  2EWB A;  1LCP A;  3GPQ A;  3SIJ A;  2X47 A;  2J9A A;  3H8F A;  3EJG A;  1YD9 A;  2JZD A;  1LAN A;  1LAP A;  3SII A;  2XD7 A;  3KR5 A;  2L8R A;  4K3N A;  2BFQ A;  4ETJ A;  3KQX A;  2FXK A;  2FG1 A;  3KZW A;  3EWQ A;  1BPM A;  5HIH A;  2ACF A;  4ZY1 A;  5D8N A;  4R7M A;  1SPV A;  1LAM A;  4ESS A;  3GQO A;  5FSV A;  3Q71 A;  4GVW A;  4ZY0 A;  4ZY2 A;  4X2T A;  3EWP A;  2RNK A;  3ETI A;  2VRI A;  1NJR A;  4TU0 A;  5CB3 A;  5FSY A;  4ZX9 A;  1TY8 A;  3V45 A;  1GYT A;  4JVV A;  2JZE A;  2DX6 A;  1VHU A;  2AFC A;  2EEE A;  3IIF A;  4J5R A;  4R6T A;  2FAV A;  4D86 A;  4ETK A;  4KYB A;  3H8G A;  1ZR3 A;  3EKE A;  5CB5 A;  5FSZ A;  3EWO A;  4IQY A;  4J4Z A;  3IJ3 A;  4K0C A;  4J5Q A;  3GQE A;  2WCT A;  4J5S A;  1BPN A;  3Q6Z A;  4R76 A;  3IID A;  5CMS A;  5DUS A;  3GPO A;  3PEI A;  3EW5 A;  3GPG A;  2KQV A;  2BFR A;  2W2G A;  4ABK A;  3EJF A;  4GUA A;  5FSX A;  3T8W A;  3V2B A;  5AIL A;  3SIG A;  4KSI A;  4GVV A; 
#chains in the Genus database with same CATH homology
 2LGR A;  1BLL E;  1HJZ A;  4ZX8 A;  5FSU A;  4ABL A;  4ZI6 A;  4JCA A;  3VFQ A;  4UML A;  4JLL A;  3SIH A;  4JGK A;  3H8E A;  3EWR A;  5E3B A;  5HOL A;  1TXZ A;  1ZR5 A;  3KR4 A;  3JRU A;  3KQZ A;  5CBM A;  4ZYQ A;  3JZT A;  2EWB A;  1LCP A;  3GPQ A;  3SIJ A;  2X47 A;  2J9A A;  3H8F A;  3EJG A;  1YD9 A;  1LAN A;  1LAP A;  3SII A;  2XD7 A;  3KR5 A;  2L8R A;  4K3N A;  2BFQ A;  4ETJ A;  3KQX A;  2FXK A;  2FG1 A;  3KZW A;  3EWQ A;  1BPM A;  5HIH A;  2ACF A;  4ZY1 A;  5D8N A;  4R7M A;  1SPV A;  1LAM A;  4ESS A;  3GQO A;  5FSV A;  3Q71 A;  4GVW A;  4ZY0 A;  4ZY2 A;  4X2T A;  3EWP A;  3ETI A;  2VRI A;  1NJR A;  4TU0 A;  5CB3 A;  5FSY A;  4ZX9 A;  1TY8 A;  3V45 A;  1GYT A;  4JVV A;  2DX6 A;  1VHU A;  2AFC A;  2EEE A;  3IIF A;  4J5R A;  4R6T A;  2FAV A;  4D86 A;  4ETK A;  4KYB A;  3H8G A;  1ZR3 A;  3EKE A;  5CB5 A;  5FSZ A;  3EWO A;  4IQY A;  4J4Z A;  3IJ3 A;  4K0C A;  4J5Q A;  3GQE A;  4J5S A;  1BPN A;  3Q6Z A;  4R76 A;  3IID A;  5CMS A;  5DUS A;  3GPO A;  3PEI A;  3EW5 A;  3GPG A;  2BFR A;  4ABK A;  3EJF A;  4GUA A;  5FSX A;  3T8W A;  3V2B A;  5AIL A;  3SIG A;  4KSI A;  4GVV A; 
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similar chains in the Genus database (?% sequence similarity)
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