4J5QA

Targ1 (c6orf130), terminal adp-ribose glycohydrolase 1, apo structure
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
146
structure length
146
Chain Sequence
EDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAMIEEVFEATDIKITVYTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.
pubmed doi rcsb
molecule keywords O-acetyl-ADP-ribose deacetylase 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 48
structure length 146
sequence length 146
ec nomenclature ec 3.5.1.-:
pdb deposition date 2013-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4j5qA01
3GQEA 3EWRA 2EWBA 3EJFA 3JRUA 1ZR5A 4R6TA 1YD9A 4J5RA 4JVVA 1LCPA 4ZX8A 3SIIA 4R7MA 2X47A 4X2TA 3JZTA 2AFCA 5E3BA 4ZY0A 1LAPA 5CMSA 4ZY2A 3ETIA 2J9AA 2FXKA 5FSYA 3IJ3A 3GPOA 3GPQA 5HIHA 3GPGA 1BPMA 2DX6A 3SIGA 5CBMA 3SIHA 3IIFA 4J5QA 4ETJA 1GYTA 3GQOA 4J5SA 4JCAA 5DUSA 2BFRA 3PEIA 3H8FA 3EW5A 4D86A 4ESSA 3EWQA 4ETKA 4JGKA 2ACFA 4UMLA 3H8GA 3KZWA 3SIJA 5CB5A 3V45A 4ZX9A 1NJRA 4GVVA 4J4ZA 3Q6ZA 4KYBA 3V2BA 1TY8A 4ZY1A 2FG1A 5AILA 1BPNA 3KR5A 4GUAA 2L8RA 4ABLA 1BLLE 4K3NA 4GVWA 1SPVA 3IIDA 3Q71A 5FSUA 1LANA 3KR4A 2XD7A 1LAMA 5D8NA 4R76A 5CB3A 1VHUA 1ZR3A 5FSVA 3KQZA 3KQXA 4ABKA 3EJGA 5FSXA 2LGRA 5HOLA 3EKEA 4JLLA 4K0CA 3VFQA 4ZI6A 4TU0A 2FAVA 3EWOA 3H8EA 4KSIA 2BFQA 2EEEA 3EWPA 1HJZA 2VRIA 5FSZA 3T8WA 1TXZA 4ZYQA 4IQYA
chains in the Genus database with same CATH superfamily
3GQEA 3EWRA 2EWBA 3EJFA 3JRUA 1ZR5A 4R6TA 1YD9A 4J5RA 4JVVA 1LCPA 4ZX8A 3SIIA 4R7MA 2X47A 4X2TA 3JZTA 2AFCA 5E3BA 4ZY0A 2KQVA 1LAPA 5CMSA 4ZY2A 3ETIA 2J9AA 2FXKA 5FSYA 3IJ3A 3GPOA 3GPQA 5HIHA 3GPGA 2JZEA 1BPMA 2DX6A 3SIGA 5CBMA 3SIHA 2RNKA 3IIFA 4J5QA 4ETJA 1GYTA 3GQOA 4J5SA 4JCAA 2W2GA 5DUSA 2BFRA 3PEIA 3H8FA 3EW5A 4D86A 2JZDA 4ESSA 3EWQA 4ETKA 4JGKA 2WCTA 2ACFA 4UMLA 3H8GA 3KZWA 3SIJA 5CB5A 3V45A 4ZX9A 2JZFA 1NJRA 4GVVA 4J4ZA 3Q6ZA 4KYBA 3V2BA 1TY8A 4ZY1A 2FG1A 5AILA 1BPNA 3KR5A 4GUAA 2L8RA 4ABLA 1BLLE 4K3NA 4GVWA 1SPVA 3IIDA 3Q71A 5FSUA 1LANA 3KR4A 2XD7A 1LAMA 5D8NA 4R76A 5CB3A 1VHUA 1ZR3A 5FSVA 3KQZA 3KQXA 4ABKA 3EJGA 5FSXA 2LGRA 5HOLA 3EKEA 4JLLA 4K0CA 3VFQA 4ZI6A 4TU0A 2FAVA 3EWOA 3H8EA 4KSIA 2BFQA 2EEEA 3EWPA 1HJZA 2VRIA 5FSZA 3T8WA 1TXZA 4ZYQA 4IQYA
chains in the Genus database with same CATH topology
3GQEA 3EWRA 2EWBA 3EJFA 3JRUA 1ZR5A 4R6TA 1YD9A 4J5RA 4JVVA 1LCPA 4ZX8A 3SIIA 4R7MA 2X47A 4X2TA 3JZTA 2AFCA 5E3BA 4ZY0A 1LAPA 5CMSA 4ZY2A 3ETIA 2J9AA 2FXKA 5FSYA 3IJ3A 3GPOA 3GPQA 5HIHA 3GPGA 1BPMA 2DX6A 3SIGA 5CBMA 3SIHA 3IIFA 4J5QA 4ETJA 1GYTA 3GQOA 4J5SA 4JCAA 5DUSA 2BFRA 3PEIA 3H8FA 3EW5A 4D86A 4ESSA 3EWQA 4ETKA 4JGKA 2ACFA 4UMLA 3H8GA 3KZWA 3SIJA 5CB5A 3V45A 4ZX9A 1NJRA 4GVVA 4J4ZA 3Q6ZA 4KYBA 3V2BA 1TY8A 4ZY1A 2FG1A 5AILA 1BPNA 3KR5A 4GUAA 2L8RA 4ABLA 1BLLE 4K3NA 4GVWA 1SPVA 3IIDA 3Q71A 5FSUA 1LANA 3KR4A 2XD7A 1LAMA 5D8NA 4R76A 5CB3A 1VHUA 1ZR3A 5FSVA 3KQZA 3KQXA 4ABKA 3EJGA 5FSXA 2LGRA 5HOLA 3EKEA 4JLLA 4K0CA 3VFQA 4ZI6A 4TU0A 2FAVA 3EWOA 3H8EA 4KSIA 2BFQA 2EEEA 3EWPA 1HJZA 2VRIA 5FSZA 3T8WA 1TXZA 4ZYQA 4IQYA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3GQE A;  3EWR A;  2EWB A;  3EJF A;  3JRU A;  1ZR5 A;  4R6T A;  1YD9 A;  4J5R A;  4JVV A;  1LCP A;  4ZX8 A;  3SII A;  4R7M A;  2X47 A;  4X2T A;  3JZT A;  2AFC A;  5E3B A;  4ZY0 A;  1LAP A;  5CMS A;  4ZY2 A;  3ETI A;  2J9A A;  2FXK A;  5FSY A;  3IJ3 A;  3GPO A;  3GPQ A;  5HIH A;  3GPG A;  1BPM A;  2DX6 A;  3SIG A;  5CBM A;  3SIH A;  3IIF A;  4J5Q A;  4ETJ A;  1GYT A;  3GQO A;  4J5S A;  4JCA A;  5DUS A;  2BFR A;  3PEI A;  3H8F A;  3EW5 A;  4D86 A;  4ESS A;  3EWQ A;  4ETK A;  4JGK A;  2ACF A;  4UML A;  3H8G A;  3KZW A;  3SIJ A;  5CB5 A;  3V45 A;  4ZX9 A;  1NJR A;  4GVV A;  4J4Z A;  3Q6Z A;  4KYB A;  3V2B A;  1TY8 A;  4ZY1 A;  2FG1 A;  5AIL A;  1BPN A;  3KR5 A;  4GUA A;  2L8R A;  4ABL A;  1BLL E;  4K3N A;  4GVW A;  1SPV A;  3IID A;  3Q71 A;  5FSU A;  1LAN A;  3KR4 A;  2XD7 A;  1LAM A;  5D8N A;  4R76 A;  5CB3 A;  1VHU A;  1ZR3 A;  5FSV A;  3KQZ A;  3KQX A;  4ABK A;  3EJG A;  5FSX A;  2LGR A;  5HOL A;  3EKE A;  4JLL A;  4K0C A;  3VFQ A;  4ZI6 A;  4TU0 A;  2FAV A;  3EWO A;  3H8E A;  4KSI A;  2BFQ A;  2EEE A;  3EWP A;  1HJZ A;  2VRI A;  5FSZ A;  3T8W A;  1TXZ A;  4ZYQ A;  4IQY A; 
#chains in the Genus database with same CATH topology
 3GQE A;  3EWR A;  2EWB A;  3EJF A;  3JRU A;  1ZR5 A;  4R6T A;  1YD9 A;  4J5R A;  4JVV A;  1LCP A;  4ZX8 A;  3SII A;  4R7M A;  2X47 A;  4X2T A;  3JZT A;  2AFC A;  5E3B A;  4ZY0 A;  2KQV A;  1LAP A;  5CMS A;  4ZY2 A;  3ETI A;  2J9A A;  2FXK A;  5FSY A;  3IJ3 A;  3GPO A;  3GPQ A;  5HIH A;  3GPG A;  2JZE A;  1BPM A;  2DX6 A;  3SIG A;  5CBM A;  3SIH A;  2RNK A;  3IIF A;  4J5Q A;  4ETJ A;  1GYT A;  3GQO A;  4J5S A;  4JCA A;  2W2G A;  5DUS A;  2BFR A;  3PEI A;  3H8F A;  3EW5 A;  4D86 A;  2JZD A;  4ESS A;  3EWQ A;  4ETK A;  4JGK A;  2WCT A;  2ACF A;  4UML A;  3H8G A;  3KZW A;  3SIJ A;  5CB5 A;  3V45 A;  4ZX9 A;  2JZF A;  1NJR A;  4GVV A;  4J4Z A;  3Q6Z A;  4KYB A;  3V2B A;  1TY8 A;  4ZY1 A;  2FG1 A;  5AIL A;  1BPN A;  3KR5 A;  4GUA A;  2L8R A;  4ABL A;  1BLL E;  4K3N A;  4GVW A;  1SPV A;  3IID A;  3Q71 A;  5FSU A;  1LAN A;  3KR4 A;  2XD7 A;  1LAM A;  5D8N A;  4R76 A;  5CB3 A;  1VHU A;  1ZR3 A;  5FSV A;  3KQZ A;  3KQX A;  4ABK A;  3EJG A;  5FSX A;  2LGR A;  5HOL A;  3EKE A;  4JLL A;  4K0C A;  3VFQ A;  4ZI6 A;  4TU0 A;  2FAV A;  3EWO A;  3H8E A;  4KSI A;  2BFQ A;  2EEE A;  3EWP A;  1HJZ A;  2VRI A;  5FSZ A;  3T8W A;  1TXZ A;  4ZYQ A;  4IQY A; 
#chains in the Genus database with same CATH homology
 3GQE A;  3EWR A;  2EWB A;  3EJF A;  3JRU A;  1ZR5 A;  4R6T A;  1YD9 A;  4J5R A;  4JVV A;  1LCP A;  4ZX8 A;  3SII A;  4R7M A;  2X47 A;  4X2T A;  3JZT A;  2AFC A;  5E3B A;  4ZY0 A;  1LAP A;  5CMS A;  4ZY2 A;  3ETI A;  2J9A A;  2FXK A;  5FSY A;  3IJ3 A;  3GPO A;  3GPQ A;  5HIH A;  3GPG A;  1BPM A;  2DX6 A;  3SIG A;  5CBM A;  3SIH A;  3IIF A;  4J5Q A;  4ETJ A;  1GYT A;  3GQO A;  4J5S A;  4JCA A;  5DUS A;  2BFR A;  3PEI A;  3H8F A;  3EW5 A;  4D86 A;  4ESS A;  3EWQ A;  4ETK A;  4JGK A;  2ACF A;  4UML A;  3H8G A;  3KZW A;  3SIJ A;  5CB5 A;  3V45 A;  4ZX9 A;  1NJR A;  4GVV A;  4J4Z A;  3Q6Z A;  4KYB A;  3V2B A;  1TY8 A;  4ZY1 A;  2FG1 A;  5AIL A;  1BPN A;  3KR5 A;  4GUA A;  2L8R A;  4ABL A;  1BLL E;  4K3N A;  4GVW A;  1SPV A;  3IID A;  3Q71 A;  5FSU A;  1LAN A;  3KR4 A;  2XD7 A;  1LAM A;  5D8N A;  4R76 A;  5CB3 A;  1VHU A;  1ZR3 A;  5FSV A;  3KQZ A;  3KQX A;  4ABK A;  3EJG A;  5FSX A;  2LGR A;  5HOL A;  3EKE A;  4JLL A;  4K0C A;  3VFQ A;  4ZI6 A;  4TU0 A;  2FAV A;  3EWO A;  3H8E A;  4KSI A;  2BFQ A;  2EEE A;  3EWP A;  1HJZ A;  2VRI A;  5FSZ A;  3T8W A;  1TXZ A;  4ZYQ A;  4IQY A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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