4J5QA

Targ1 (c6orf130), terminal adp-ribose glycohydrolase 1, apo structure
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
146
structure length
146
Chain Sequence
EDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAMIEEVFEATDIKITVYTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords O-acetyl-ADP-ribose deacetylase 1
publication title Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.
pubmed doi rcsb
source organism Homo sapiens
total genus 48
structure length 146
sequence length 146
ec nomenclature ec 3.5.1.-:
pdb deposition date 2013-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4j5qA01
4K0CA 4JGKA 4J5QA 4R7MA 5DUSA 1GYTA 1BPNA 3SIGA 3SIIA 4ZYQA 4ZY0A 3IIFA 4ETKA 3KR5A 4JLLA 2L8RA 4JVVA 5FSVA 3H8FA 3GPQA 3H8EA 2LGRA 3KQXA 5FSXA 5FSYA 3SIHA 2J9AA 4ABKA 3T8WA 4IQYA 3SIJA 3GPOA 1LAPA 4TU0A 4GVVA 1YD9A 2EWBA 3Q6ZA 4J5SA 2AFCA 4KSIA 4ETJA 2ACFA 4GVWA 4GUAA 1BPMA 1BLLE 3EWOA 4ZY2A 1VHUA 3IJ3A 5CBMA 3GQOA 3PEIA 3V2BA 3EWPA 4K3NA 4UMLA 2FAVA 5FSUA 5HIHA 1TXZA 4R76A 1ZR3A 5AILA 5CMSA 3EW5A 2BFQA 3GQEA 4J4ZA 2FXKA 2DX6A 3ETIA 3VFQA 4ZX8A 3V45A 4J5RA 1ZR5A 5E3BA 4ZX9A 5FSZA 3KZWA 1NJRA 3EKEA 3JRUA 3JZTA 5D8NA 4ABLA 4KYBA 4X2TA 3KQZA 5HOLA 2FG1A 4D86A 3IIDA 4ZY1A 3EJFA 3EWRA 2BFRA 2EEEA 3Q71A 4ESSA 5CB5A 3EJGA 3EWQA 2VRIA 5CB3A 1LCPA 4ZI6A 1TY8A 1SPVA 1LAMA 2XD7A 3KR4A 1HJZA 1LANA 2X47A 3GPGA 4JCAA 3H8GA 4R6TA
chains in the Genus database with same CATH superfamily
4K0CA 4JGKA 4J5QA 4R7MA 5DUSA 1GYTA 1BPNA 3SIGA 3SIIA 4ZYQA 4ZY0A 3IIFA 4ETKA 3KR5A 4JLLA 2L8RA 4JVVA 5FSVA 3H8FA 3GPQA 3H8EA 2LGRA 3KQXA 5FSXA 5FSYA 3SIHA 2J9AA 4ABKA 3T8WA 4IQYA 2JZFA 3SIJA 3GPOA 1LAPA 4TU0A 4GVVA 1YD9A 2EWBA 3Q6ZA 4J5SA 2AFCA 4KSIA 4ETJA 2ACFA 4GVWA 4GUAA 1BPMA 1BLLE 3EWOA 4ZY2A 1VHUA 3IJ3A 5CBMA 3GQOA 3PEIA 3V2BA 3EWPA 4K3NA 4UMLA 2FAVA 2RNKA 5FSUA 5HIHA 1TXZA 4R76A 1ZR3A 5AILA 5CMSA 2W2GA 3EW5A 2BFQA 3GQEA 4J4ZA 2FXKA 2DX6A 3ETIA 3VFQA 4ZX8A 3V45A 4J5RA 1ZR5A 5E3BA 2JZDA 4ZX9A 5FSZA 3KZWA 1NJRA 3EKEA 2JZEA 3JRUA 3JZTA 5D8NA 4ABLA 4KYBA 4X2TA 3KQZA 5HOLA 2FG1A 4D86A 2WCTA 3IIDA 4ZY1A 3EJFA 3EWRA 2BFRA 2EEEA 3Q71A 4ESSA 5CB5A 3EJGA 3EWQA 2VRIA 5CB3A 1LCPA 4ZI6A 1TY8A 1SPVA 2KQVA 1LAMA 2XD7A 3KR4A 1HJZA 1LANA 2X47A 3GPGA 4JCAA 3H8GA 4R6TA
chains in the Genus database with same CATH topology
4K0CA 4JGKA 4J5QA 4R7MA 5DUSA 1GYTA 1BPNA 3SIGA 3SIIA 4ZYQA 4ZY0A 3IIFA 4ETKA 3KR5A 4JLLA 2L8RA 4JVVA 5FSVA 3H8FA 3GPQA 3H8EA 2LGRA 3KQXA 5FSXA 5FSYA 3SIHA 2J9AA 4ABKA 3T8WA 4IQYA 3SIJA 3GPOA 1LAPA 4TU0A 4GVVA 1YD9A 2EWBA 3Q6ZA 4J5SA 2AFCA 4KSIA 4ETJA 2ACFA 4GVWA 4GUAA 1BPMA 1BLLE 3EWOA 4ZY2A 1VHUA 3IJ3A 5CBMA 3GQOA 3PEIA 3V2BA 3EWPA 4K3NA 4UMLA 2FAVA 5FSUA 5HIHA 1TXZA 4R76A 1ZR3A 5AILA 5CMSA 3EW5A 2BFQA 3GQEA 4J4ZA 2FXKA 2DX6A 3ETIA 3VFQA 4ZX8A 3V45A 4J5RA 1ZR5A 5E3BA 4ZX9A 5FSZA 3KZWA 1NJRA 3EKEA 3JRUA 3JZTA 5D8NA 4ABLA 4KYBA 4X2TA 3KQZA 5HOLA 2FG1A 4D86A 3IIDA 4ZY1A 3EJFA 3EWRA 2BFRA 2EEEA 3Q71A 4ESSA 5CB5A 3EJGA 3EWQA 2VRIA 5CB3A 1LCPA 4ZI6A 1TY8A 1SPVA 1LAMA 2XD7A 3KR4A 1HJZA 1LANA 2X47A 3GPGA 4JCAA 3H8GA 4R6TA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4K0C A;  4JGK A;  4J5Q A;  4R7M A;  5DUS A;  1GYT A;  1BPN A;  3SIG A;  3SII A;  4ZYQ A;  4ZY0 A;  3IIF A;  4ETK A;  3KR5 A;  4JLL A;  2L8R A;  4JVV A;  5FSV A;  3H8F A;  3GPQ A;  3H8E A;  2LGR A;  3KQX A;  5FSX A;  5FSY A;  3SIH A;  2J9A A;  4ABK A;  3T8W A;  4IQY A;  3SIJ A;  3GPO A;  1LAP A;  4TU0 A;  4GVV A;  1YD9 A;  2EWB A;  3Q6Z A;  4J5S A;  2AFC A;  4KSI A;  4ETJ A;  2ACF A;  4GVW A;  4GUA A;  1BPM A;  1BLL E;  3EWO A;  4ZY2 A;  1VHU A;  3IJ3 A;  5CBM A;  3GQO A;  3PEI A;  3V2B A;  3EWP A;  4K3N A;  4UML A;  2FAV A;  5FSU A;  5HIH A;  1TXZ A;  4R76 A;  1ZR3 A;  5AIL A;  5CMS A;  3EW5 A;  2BFQ A;  3GQE A;  4J4Z A;  2FXK A;  2DX6 A;  3ETI A;  3VFQ A;  4ZX8 A;  3V45 A;  4J5R A;  1ZR5 A;  5E3B A;  4ZX9 A;  5FSZ A;  3KZW A;  1NJR A;  3EKE A;  3JRU A;  3JZT A;  5D8N A;  4ABL A;  4KYB A;  4X2T A;  3KQZ A;  5HOL A;  2FG1 A;  4D86 A;  3IID A;  4ZY1 A;  3EJF A;  3EWR A;  2BFR A;  2EEE A;  3Q71 A;  4ESS A;  5CB5 A;  3EJG A;  3EWQ A;  2VRI A;  5CB3 A;  1LCP A;  4ZI6 A;  1TY8 A;  1SPV A;  1LAM A;  2XD7 A;  3KR4 A;  1HJZ A;  1LAN A;  2X47 A;  3GPG A;  4JCA A;  3H8G A;  4R6T A; 
#chains in the Genus database with same CATH topology
 4K0C A;  4JGK A;  4J5Q A;  4R7M A;  5DUS A;  1GYT A;  1BPN A;  3SIG A;  3SII A;  4ZYQ A;  4ZY0 A;  3IIF A;  4ETK A;  3KR5 A;  4JLL A;  2L8R A;  4JVV A;  5FSV A;  3H8F A;  3GPQ A;  3H8E A;  2LGR A;  3KQX A;  5FSX A;  5FSY A;  3SIH A;  2J9A A;  4ABK A;  3T8W A;  4IQY A;  2JZF A;  3SIJ A;  3GPO A;  1LAP A;  4TU0 A;  4GVV A;  1YD9 A;  2EWB A;  3Q6Z A;  4J5S A;  2AFC A;  4KSI A;  4ETJ A;  2ACF A;  4GVW A;  4GUA A;  1BPM A;  1BLL E;  3EWO A;  4ZY2 A;  1VHU A;  3IJ3 A;  5CBM A;  3GQO A;  3PEI A;  3V2B A;  3EWP A;  4K3N A;  4UML A;  2FAV A;  2RNK A;  5FSU A;  5HIH A;  1TXZ A;  4R76 A;  1ZR3 A;  5AIL A;  5CMS A;  2W2G A;  3EW5 A;  2BFQ A;  3GQE A;  4J4Z A;  2FXK A;  2DX6 A;  3ETI A;  3VFQ A;  4ZX8 A;  3V45 A;  4J5R A;  1ZR5 A;  5E3B A;  2JZD A;  4ZX9 A;  5FSZ A;  3KZW A;  1NJR A;  3EKE A;  2JZE A;  3JRU A;  3JZT A;  5D8N A;  4ABL A;  4KYB A;  4X2T A;  3KQZ A;  5HOL A;  2FG1 A;  4D86 A;  2WCT A;  3IID A;  4ZY1 A;  3EJF A;  3EWR A;  2BFR A;  2EEE A;  3Q71 A;  4ESS A;  5CB5 A;  3EJG A;  3EWQ A;  2VRI A;  5CB3 A;  1LCP A;  4ZI6 A;  1TY8 A;  1SPV A;  2KQV A;  1LAM A;  2XD7 A;  3KR4 A;  1HJZ A;  1LAN A;  2X47 A;  3GPG A;  4JCA A;  3H8G A;  4R6T A; 
#chains in the Genus database with same CATH homology
 4K0C A;  4JGK A;  4J5Q A;  4R7M A;  5DUS A;  1GYT A;  1BPN A;  3SIG A;  3SII A;  4ZYQ A;  4ZY0 A;  3IIF A;  4ETK A;  3KR5 A;  4JLL A;  2L8R A;  4JVV A;  5FSV A;  3H8F A;  3GPQ A;  3H8E A;  2LGR A;  3KQX A;  5FSX A;  5FSY A;  3SIH A;  2J9A A;  4ABK A;  3T8W A;  4IQY A;  3SIJ A;  3GPO A;  1LAP A;  4TU0 A;  4GVV A;  1YD9 A;  2EWB A;  3Q6Z A;  4J5S A;  2AFC A;  4KSI A;  4ETJ A;  2ACF A;  4GVW A;  4GUA A;  1BPM A;  1BLL E;  3EWO A;  4ZY2 A;  1VHU A;  3IJ3 A;  5CBM A;  3GQO A;  3PEI A;  3V2B A;  3EWP A;  4K3N A;  4UML A;  2FAV A;  5FSU A;  5HIH A;  1TXZ A;  4R76 A;  1ZR3 A;  5AIL A;  5CMS A;  3EW5 A;  2BFQ A;  3GQE A;  4J4Z A;  2FXK A;  2DX6 A;  3ETI A;  3VFQ A;  4ZX8 A;  3V45 A;  4J5R A;  1ZR5 A;  5E3B A;  4ZX9 A;  5FSZ A;  3KZW A;  1NJR A;  3EKE A;  3JRU A;  3JZT A;  5D8N A;  4ABL A;  4KYB A;  4X2T A;  3KQZ A;  5HOL A;  2FG1 A;  4D86 A;  3IID A;  4ZY1 A;  3EJF A;  3EWR A;  2BFR A;  2EEE A;  3Q71 A;  4ESS A;  5CB5 A;  3EJG A;  3EWQ A;  2VRI A;  5CB3 A;  1LCP A;  4ZI6 A;  1TY8 A;  1SPV A;  1LAM A;  2XD7 A;  3KR4 A;  1HJZ A;  1LAN A;  2X47 A;  3GPG A;  4JCA A;  3H8G A;  4R6T A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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