4JCAA

Crystal structure of the apo form of the evolved variant of the computationally designed serine hydrolase, osh55.4_h1. northeast structural genomics consortium (nesg) target or273
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
160
structure length
160
Chain Sequence
RIRHVQGDITEFQGDAIVNAANNYLKLGAGVAGAILRKGGPSIQEECDRIGKIRVGEAAVTGAGNLPVRYVIHAAVLGDEPASLETVRKATKSALEKAVELGLKTVAFTSWGAWVGGLPAEAVHRVMGEEIKKAPDTLEVTGVHGTEKSAEAYRRASLEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design of activated serine-containing catalytic triads with atomic-level accuracy.
pubmed doi rcsb
molecule keywords serine hydrolase
molecule tags Hydrolase
source organism Artificial gene
total genus 60
structure length 160
sequence length 160
ec nomenclature
pdb deposition date 2013-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4jcaA00
1VHUA 4JVVA 2EWBA 4R6TA 5FSXA 1BPMA 1ZR3A 4ZY0A 3H8EA 3V45A 3PEIA 1SPVA 4ESSA 2J9AA 4ABKA 4ZY1A 2BFRA 4ZI6A 1NJRA 2EEEA 5AILA 2FAVA 3IIFA 3SIGA 1LCPA 5DUSA 5HOLA 4K3NA 4ETJA 2DX6A 1GYTA 3GPQA 4GUAA 5E3BA 3T8WA 4ABLA 3Q6ZA 5FSUA 3EW5A 1LAMA 1BPNA 3KR5A 2FXKA 2VRIA 3EJGA 2FG1A 4ZY2A 1YD9A 4J5SA 3EWPA 1HJZA 5CB5A 4ZX8A 5FSVA 3H8GA 4GVVA 3SIIA 4UMLA 4ETKA 1TXZA 3KZWA 4J4ZA 4K0CA 1BLLE 3V2BA 4TU0A 4ZX9A 2XD7A 3ETIA 4X2TA 5HIHA 2BFQA 4J5QA 3KR4A 1LANA 1ZR5A 3EWRA 4J5RA 2AFCA 4JCAA 3VFQA 3SIHA 4JLLA 3JRUA 3EWOA 3SIJA 4JGKA 3KQXA 4R7MA 5CBMA 3IIDA 4R76A 3Q71A 3EWQA 4GVWA 2L8RA 1TY8A 4D86A 5FSZA 3GPGA 2ACFA 5D8NA 3EKEA 2X47A 4ZYQA 3H8FA 3KQZA 3GQOA 3EJFA 4KSIA 2LGRA 1LAPA 3GPOA 3JZTA 5CMSA 3GQEA 5FSYA 4IQYA 3IJ3A 4KYBA 5CB3A
chains in the Genus database with same CATH superfamily
1VHUA 4JVVA 2EWBA 4R6TA 5FSXA 1BPMA 1ZR3A 4ZY0A 3H8EA 3V45A 3PEIA 1SPVA 4ESSA 2J9AA 4ABKA 4ZY1A 2BFRA 4ZI6A 1NJRA 2EEEA 5AILA 2FAVA 3IIFA 3SIGA 1LCPA 5DUSA 5HOLA 4K3NA 4ETJA 2DX6A 1GYTA 3GPQA 4GUAA 5E3BA 3T8WA 4ABLA 3Q6ZA 5FSUA 3EW5A 1LAMA 1BPNA 3KR5A 2FXKA 2VRIA 3EJGA 2FG1A 2JZEA 2JZFA 4ZY2A 1YD9A 4J5SA 3EWPA 1HJZA 5CB5A 4ZX8A 5FSVA 2W2GA 3H8GA 4GVVA 3SIIA 2WCTA 4UMLA 4ETKA 1TXZA 3KZWA 4J4ZA 4K0CA 1BLLE 3V2BA 4TU0A 4ZX9A 2XD7A 3ETIA 4X2TA 5HIHA 2BFQA 4J5QA 3KR4A 1LANA 1ZR5A 2RNKA 3EWRA 4J5RA 2AFCA 4JCAA 3VFQA 3SIHA 4JLLA 3JRUA 3EWOA 3SIJA 4JGKA 3KQXA 4R7MA 5CBMA 3IIDA 4R76A 3Q71A 3EWQA 4GVWA 2L8RA 1TY8A 4D86A 5FSZA 3GPGA 2ACFA 5D8NA 3EKEA 2X47A 4ZYQA 3H8FA 3KQZA 3GQOA 3EJFA 4KSIA 2KQVA 2LGRA 1LAPA 3GPOA 3JZTA 5CMSA 3GQEA 5FSYA 4IQYA 3IJ3A 4KYBA 2JZDA 5CB3A
chains in the Genus database with same CATH topology
1VHUA 4JVVA 2EWBA 4R6TA 5FSXA 1BPMA 1ZR3A 4ZY0A 3H8EA 3V45A 3PEIA 1SPVA 4ESSA 2J9AA 4ABKA 4ZY1A 2BFRA 4ZI6A 1NJRA 2EEEA 5AILA 2FAVA 3IIFA 3SIGA 1LCPA 5DUSA 5HOLA 4K3NA 4ETJA 2DX6A 1GYTA 3GPQA 4GUAA 5E3BA 3T8WA 4ABLA 3Q6ZA 5FSUA 3EW5A 1LAMA 1BPNA 3KR5A 2FXKA 2VRIA 3EJGA 2FG1A 4ZY2A 1YD9A 4J5SA 3EWPA 1HJZA 5CB5A 4ZX8A 5FSVA 3H8GA 4GVVA 3SIIA 4UMLA 4ETKA 1TXZA 3KZWA 4J4ZA 4K0CA 1BLLE 3V2BA 4TU0A 4ZX9A 2XD7A 3ETIA 4X2TA 5HIHA 2BFQA 4J5QA 3KR4A 1LANA 1ZR5A 3EWRA 4J5RA 2AFCA 4JCAA 3VFQA 3SIHA 4JLLA 3JRUA 3EWOA 3SIJA 4JGKA 3KQXA 4R7MA 5CBMA 3IIDA 4R76A 3Q71A 3EWQA 4GVWA 2L8RA 1TY8A 4D86A 5FSZA 3GPGA 2ACFA 5D8NA 3EKEA 2X47A 4ZYQA 3H8FA 3KQZA 3GQOA 3EJFA 4KSIA 2LGRA 1LAPA 3GPOA 3JZTA 5CMSA 3GQEA 5FSYA 4IQYA 3IJ3A 4KYBA 5CB3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VHU A;  4JVV A;  2EWB A;  4R6T A;  5FSX A;  1BPM A;  1ZR3 A;  4ZY0 A;  3H8E A;  3V45 A;  3PEI A;  1SPV A;  4ESS A;  2J9A A;  4ABK A;  4ZY1 A;  2BFR A;  4ZI6 A;  1NJR A;  2EEE A;  5AIL A;  2FAV A;  3IIF A;  3SIG A;  1LCP A;  5DUS A;  5HOL A;  4K3N A;  4ETJ A;  2DX6 A;  1GYT A;  3GPQ A;  4GUA A;  5E3B A;  3T8W A;  4ABL A;  3Q6Z A;  5FSU A;  3EW5 A;  1LAM A;  1BPN A;  3KR5 A;  2FXK A;  2VRI A;  3EJG A;  2FG1 A;  4ZY2 A;  1YD9 A;  4J5S A;  3EWP A;  1HJZ A;  5CB5 A;  4ZX8 A;  5FSV A;  3H8G A;  4GVV A;  3SII A;  4UML A;  4ETK A;  1TXZ A;  3KZW A;  4J4Z A;  4K0C A;  1BLL E;  3V2B A;  4TU0 A;  4ZX9 A;  2XD7 A;  3ETI A;  4X2T A;  5HIH A;  2BFQ A;  4J5Q A;  3KR4 A;  1LAN A;  1ZR5 A;  3EWR A;  4J5R A;  2AFC A;  4JCA A;  3VFQ A;  3SIH A;  4JLL A;  3JRU A;  3EWO A;  3SIJ A;  4JGK A;  3KQX A;  4R7M A;  5CBM A;  3IID A;  4R76 A;  3Q71 A;  3EWQ A;  4GVW A;  2L8R A;  1TY8 A;  4D86 A;  5FSZ A;  3GPG A;  2ACF A;  5D8N A;  3EKE A;  2X47 A;  4ZYQ A;  3H8F A;  3KQZ A;  3GQO A;  3EJF A;  4KSI A;  2LGR A;  1LAP A;  3GPO A;  3JZT A;  5CMS A;  3GQE A;  5FSY A;  4IQY A;  3IJ3 A;  4KYB A;  5CB3 A; 
#chains in the Genus database with same CATH topology
 1VHU A;  4JVV A;  2EWB A;  4R6T A;  5FSX A;  1BPM A;  1ZR3 A;  4ZY0 A;  3H8E A;  3V45 A;  3PEI A;  1SPV A;  4ESS A;  2J9A A;  4ABK A;  4ZY1 A;  2BFR A;  4ZI6 A;  1NJR A;  2EEE A;  5AIL A;  2FAV A;  3IIF A;  3SIG A;  1LCP A;  5DUS A;  5HOL A;  4K3N A;  4ETJ A;  2DX6 A;  1GYT A;  3GPQ A;  4GUA A;  5E3B A;  3T8W A;  4ABL A;  3Q6Z A;  5FSU A;  3EW5 A;  1LAM A;  1BPN A;  3KR5 A;  2FXK A;  2VRI A;  3EJG A;  2FG1 A;  2JZE A;  2JZF A;  4ZY2 A;  1YD9 A;  4J5S A;  3EWP A;  1HJZ A;  5CB5 A;  4ZX8 A;  5FSV A;  2W2G A;  3H8G A;  4GVV A;  3SII A;  2WCT A;  4UML A;  4ETK A;  1TXZ A;  3KZW A;  4J4Z A;  4K0C A;  1BLL E;  3V2B A;  4TU0 A;  4ZX9 A;  2XD7 A;  3ETI A;  4X2T A;  5HIH A;  2BFQ A;  4J5Q A;  3KR4 A;  1LAN A;  1ZR5 A;  2RNK A;  3EWR A;  4J5R A;  2AFC A;  4JCA A;  3VFQ A;  3SIH A;  4JLL A;  3JRU A;  3EWO A;  3SIJ A;  4JGK A;  3KQX A;  4R7M A;  5CBM A;  3IID A;  4R76 A;  3Q71 A;  3EWQ A;  4GVW A;  2L8R A;  1TY8 A;  4D86 A;  5FSZ A;  3GPG A;  2ACF A;  5D8N A;  3EKE A;  2X47 A;  4ZYQ A;  3H8F A;  3KQZ A;  3GQO A;  3EJF A;  4KSI A;  2KQV A;  2LGR A;  1LAP A;  3GPO A;  3JZT A;  5CMS A;  3GQE A;  5FSY A;  4IQY A;  3IJ3 A;  4KYB A;  2JZD A;  5CB3 A; 
#chains in the Genus database with same CATH homology
 1VHU A;  4JVV A;  2EWB A;  4R6T A;  5FSX A;  1BPM A;  1ZR3 A;  4ZY0 A;  3H8E A;  3V45 A;  3PEI A;  1SPV A;  4ESS A;  2J9A A;  4ABK A;  4ZY1 A;  2BFR A;  4ZI6 A;  1NJR A;  2EEE A;  5AIL A;  2FAV A;  3IIF A;  3SIG A;  1LCP A;  5DUS A;  5HOL A;  4K3N A;  4ETJ A;  2DX6 A;  1GYT A;  3GPQ A;  4GUA A;  5E3B A;  3T8W A;  4ABL A;  3Q6Z A;  5FSU A;  3EW5 A;  1LAM A;  1BPN A;  3KR5 A;  2FXK A;  2VRI A;  3EJG A;  2FG1 A;  4ZY2 A;  1YD9 A;  4J5S A;  3EWP A;  1HJZ A;  5CB5 A;  4ZX8 A;  5FSV A;  3H8G A;  4GVV A;  3SII A;  4UML A;  4ETK A;  1TXZ A;  3KZW A;  4J4Z A;  4K0C A;  1BLL E;  3V2B A;  4TU0 A;  4ZX9 A;  2XD7 A;  3ETI A;  4X2T A;  5HIH A;  2BFQ A;  4J5Q A;  3KR4 A;  1LAN A;  1ZR5 A;  3EWR A;  4J5R A;  2AFC A;  4JCA A;  3VFQ A;  3SIH A;  4JLL A;  3JRU A;  3EWO A;  3SIJ A;  4JGK A;  3KQX A;  4R7M A;  5CBM A;  3IID A;  4R76 A;  3Q71 A;  3EWQ A;  4GVW A;  2L8R A;  1TY8 A;  4D86 A;  5FSZ A;  3GPG A;  2ACF A;  5D8N A;  3EKE A;  2X47 A;  4ZYQ A;  3H8F A;  3KQZ A;  3GQO A;  3EJF A;  4KSI A;  2LGR A;  1LAP A;  3GPO A;  3JZT A;  5CMS A;  3GQE A;  5FSY A;  4IQY A;  3IJ3 A;  4KYB A;  5CB3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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