4JGKA

Crystal structure of the evolved variant of the computationally designed serine hydrolase, northeast structural genomics consortium (nesg) target or275
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
164
structure length
164
Chain Sequence
ARIRHVQGDITEFQGDAIVNAANNYLKLGAGVAGAILRKGGPSIQEECDRIGKIRVGEAAVTGAGNLPVRYVIHAAVLGDEPASLETVRKATKSALEKAVELGLKTVAFTGVGAWVGGLPAEAVYRVMLEEIKKAPDTLEVTGVHGTEKSAEAFRRAGLEHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275
rcsb
molecule keywords evolved variant of a designed serine hydrolase
molecule tags Structural genomics, unknown function
source organism Synthetic construct
total genus 54
structure length 164
sequence length 164
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-03-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4jgkA00
3KR5A 3T8WA 2AFCA 5HOLA 3IJ3A 3EWQA 4R7MA 5FSUA 4UMLA 4J5SA 3EKEA 5FSVA 3GQEA 2FAVA 2VRIA 2XD7A 3JZTA 5HIHA 4J4ZA 2LGRA 4ZI6A 5FSYA 3KQXA 5FSXA 3V45A 4ABLA 1BPNA 4J5QA 5DUSA 3EJGA 4JVVA 4J5RA 3PEIA 3KQZA 4ESSA 4IQYA 3EWOA 2X47A 3SIHA 3JRUA 4GUAA 3GQOA 4GVWA 4KSIA 3EJFA 1TY8A 3GPQA 3SIJA 5AILA 3KZWA 1VHUA 2DX6A 2EEEA 1ZR3A 3SIGA 4ETJA 4GVVA 3ETIA 1ZR5A 4ZY0A 2BFQA 4X2TA 3GPGA 5D8NA 2ACFA 4ETKA 4JLLA 1LAPA 3H8EA 2FXKA 3H8FA 4KYBA 4ZY2A 3IIDA 2L8RA 3VFQA 3H8GA 3GPOA 1HJZA 5CBMA 1LAMA 1YD9A 5CB5A 2EWBA 5CMSA 4JCAA 1BPMA 4JGKA 1SPVA 2FG1A 5FSZA 1LANA 1GYTA 3SIIA 3EWPA 3Q6ZA 4ZY1A 3KR4A 5E3BA 5CB3A 1NJRA 4K0CA 4K3NA 4ZX9A 1BLLE 4ZYQA 4ABKA 4D86A 4TU0A 2J9AA 3Q71A 1LCPA 3EWRA 4R6TA 4ZX8A 4R76A 1TXZA 3EW5A 3V2BA 2BFRA 3IIFA
chains in the Genus database with same CATH superfamily
3KR5A 3T8WA 2AFCA 5HOLA 3IJ3A 3EWQA 4R7MA 5FSUA 4UMLA 4J5SA 3EKEA 5FSVA 3GQEA 2FAVA 2VRIA 2XD7A 3JZTA 5HIHA 4J4ZA 2LGRA 4ZI6A 5FSYA 3KQXA 5FSXA 3V45A 4ABLA 1BPNA 4J5QA 5DUSA 3EJGA 4JVVA 4J5RA 3PEIA 3KQZA 4ESSA 4IQYA 2RNKA 3EWOA 2X47A 3SIHA 3JRUA 4GUAA 3GQOA 4GVWA 4KSIA 3EJFA 1TY8A 3GPQA 3SIJA 5AILA 3KZWA 1VHUA 2DX6A 2EEEA 1ZR3A 3SIGA 4ETJA 4GVVA 3ETIA 1ZR5A 4ZY0A 2BFQA 4X2TA 3GPGA 5D8NA 2ACFA 2WCTA 4JLLA 4ETKA 1LAPA 3H8EA 2FXKA 3H8FA 4KYBA 4ZY2A 3IIDA 2L8RA 3VFQA 3H8GA 3GPOA 1HJZA 5CBMA 1LAMA 1YD9A 5CB5A 2JZDA 2EWBA 5CMSA 4JCAA 1BPMA 4JGKA 1SPVA 2FG1A 5FSZA 1LANA 1GYTA 3SIIA 2JZEA 3EWPA 3Q6ZA 4ZY1A 3KR4A 5E3BA 5CB3A 1NJRA 4K0CA 4K3NA 4ZX9A 1BLLE 2KQVA 4ZYQA 4ABKA 4D86A 4TU0A 2J9AA 2JZFA 3Q71A 1LCPA 3EWRA 4R6TA 4ZX8A 4R76A 1TXZA 3EW5A 2W2GA 3V2BA 2BFRA 3IIFA
chains in the Genus database with same CATH topology
3KR5A 3T8WA 2AFCA 5HOLA 3IJ3A 3EWQA 4R7MA 5FSUA 4UMLA 4J5SA 3EKEA 5FSVA 3GQEA 2FAVA 2VRIA 2XD7A 3JZTA 5HIHA 4J4ZA 2LGRA 4ZI6A 5FSYA 3KQXA 5FSXA 3V45A 4ABLA 1BPNA 4J5QA 5DUSA 3EJGA 4JVVA 4J5RA 3PEIA 3KQZA 4ESSA 4IQYA 3EWOA 2X47A 3SIHA 3JRUA 4GUAA 3GQOA 4GVWA 4KSIA 3EJFA 1TY8A 3GPQA 3SIJA 5AILA 3KZWA 1VHUA 2DX6A 2EEEA 1ZR3A 3SIGA 4ETJA 4GVVA 3ETIA 1ZR5A 4ZY0A 2BFQA 4X2TA 3GPGA 5D8NA 2ACFA 4ETKA 4JLLA 1LAPA 3H8EA 2FXKA 3H8FA 4KYBA 4ZY2A 3IIDA 2L8RA 3VFQA 3H8GA 3GPOA 1HJZA 5CBMA 1LAMA 1YD9A 5CB5A 2EWBA 5CMSA 4JCAA 1BPMA 4JGKA 1SPVA 2FG1A 5FSZA 1LANA 1GYTA 3SIIA 3EWPA 3Q6ZA 4ZY1A 3KR4A 5E3BA 5CB3A 1NJRA 4K0CA 4K3NA 4ZX9A 1BLLE 4ZYQA 4ABKA 4D86A 4TU0A 2J9AA 3Q71A 1LCPA 3EWRA 4R6TA 4ZX8A 4R76A 1TXZA 3EW5A 3V2BA 2BFRA 3IIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KR5 A;  3T8W A;  2AFC A;  5HOL A;  3IJ3 A;  3EWQ A;  4R7M A;  5FSU A;  4UML A;  4J5S A;  3EKE A;  5FSV A;  3GQE A;  2FAV A;  2VRI A;  2XD7 A;  3JZT A;  5HIH A;  4J4Z A;  2LGR A;  4ZI6 A;  5FSY A;  3KQX A;  5FSX A;  3V45 A;  4ABL A;  1BPN A;  4J5Q A;  5DUS A;  3EJG A;  4JVV A;  4J5R A;  3PEI A;  3KQZ A;  4ESS A;  4IQY A;  3EWO A;  2X47 A;  3SIH A;  3JRU A;  4GUA A;  3GQO A;  4GVW A;  4KSI A;  3EJF A;  1TY8 A;  3GPQ A;  3SIJ A;  5AIL A;  3KZW A;  1VHU A;  2DX6 A;  2EEE A;  1ZR3 A;  3SIG A;  4ETJ A;  4GVV A;  3ETI A;  1ZR5 A;  4ZY0 A;  2BFQ A;  4X2T A;  3GPG A;  5D8N A;  2ACF A;  4ETK A;  4JLL A;  1LAP A;  3H8E A;  2FXK A;  3H8F A;  4KYB A;  4ZY2 A;  3IID A;  2L8R A;  3VFQ A;  3H8G A;  3GPO A;  1HJZ A;  5CBM A;  1LAM A;  1YD9 A;  5CB5 A;  2EWB A;  5CMS A;  4JCA A;  1BPM A;  4JGK A;  1SPV A;  2FG1 A;  5FSZ A;  1LAN A;  1GYT A;  3SII A;  3EWP A;  3Q6Z A;  4ZY1 A;  3KR4 A;  5E3B A;  5CB3 A;  1NJR A;  4K0C A;  4K3N A;  4ZX9 A;  1BLL E;  4ZYQ A;  4ABK A;  4D86 A;  4TU0 A;  2J9A A;  3Q71 A;  1LCP A;  3EWR A;  4R6T A;  4ZX8 A;  4R76 A;  1TXZ A;  3EW5 A;  3V2B A;  2BFR A;  3IIF A; 
#chains in the Genus database with same CATH topology
 3KR5 A;  3T8W A;  2AFC A;  5HOL A;  3IJ3 A;  3EWQ A;  4R7M A;  5FSU A;  4UML A;  4J5S A;  3EKE A;  5FSV A;  3GQE A;  2FAV A;  2VRI A;  2XD7 A;  3JZT A;  5HIH A;  4J4Z A;  2LGR A;  4ZI6 A;  5FSY A;  3KQX A;  5FSX A;  3V45 A;  4ABL A;  1BPN A;  4J5Q A;  5DUS A;  3EJG A;  4JVV A;  4J5R A;  3PEI A;  3KQZ A;  4ESS A;  4IQY A;  2RNK A;  3EWO A;  2X47 A;  3SIH A;  3JRU A;  4GUA A;  3GQO A;  4GVW A;  4KSI A;  3EJF A;  1TY8 A;  3GPQ A;  3SIJ A;  5AIL A;  3KZW A;  1VHU A;  2DX6 A;  2EEE A;  1ZR3 A;  3SIG A;  4ETJ A;  4GVV A;  3ETI A;  1ZR5 A;  4ZY0 A;  2BFQ A;  4X2T A;  3GPG A;  5D8N A;  2ACF A;  2WCT A;  4JLL A;  4ETK A;  1LAP A;  3H8E A;  2FXK A;  3H8F A;  4KYB A;  4ZY2 A;  3IID A;  2L8R A;  3VFQ A;  3H8G A;  3GPO A;  1HJZ A;  5CBM A;  1LAM A;  1YD9 A;  5CB5 A;  2JZD A;  2EWB A;  5CMS A;  4JCA A;  1BPM A;  4JGK A;  1SPV A;  2FG1 A;  5FSZ A;  1LAN A;  1GYT A;  3SII A;  2JZE A;  3EWP A;  3Q6Z A;  4ZY1 A;  3KR4 A;  5E3B A;  5CB3 A;  1NJR A;  4K0C A;  4K3N A;  4ZX9 A;  1BLL E;  2KQV A;  4ZYQ A;  4ABK A;  4D86 A;  4TU0 A;  2J9A A;  2JZF A;  3Q71 A;  1LCP A;  3EWR A;  4R6T A;  4ZX8 A;  4R76 A;  1TXZ A;  3EW5 A;  2W2G A;  3V2B A;  2BFR A;  3IIF A; 
#chains in the Genus database with same CATH homology
 3KR5 A;  3T8W A;  2AFC A;  5HOL A;  3IJ3 A;  3EWQ A;  4R7M A;  5FSU A;  4UML A;  4J5S A;  3EKE A;  5FSV A;  3GQE A;  2FAV A;  2VRI A;  2XD7 A;  3JZT A;  5HIH A;  4J4Z A;  2LGR A;  4ZI6 A;  5FSY A;  3KQX A;  5FSX A;  3V45 A;  4ABL A;  1BPN A;  4J5Q A;  5DUS A;  3EJG A;  4JVV A;  4J5R A;  3PEI A;  3KQZ A;  4ESS A;  4IQY A;  3EWO A;  2X47 A;  3SIH A;  3JRU A;  4GUA A;  3GQO A;  4GVW A;  4KSI A;  3EJF A;  1TY8 A;  3GPQ A;  3SIJ A;  5AIL A;  3KZW A;  1VHU A;  2DX6 A;  2EEE A;  1ZR3 A;  3SIG A;  4ETJ A;  4GVV A;  3ETI A;  1ZR5 A;  4ZY0 A;  2BFQ A;  4X2T A;  3GPG A;  5D8N A;  2ACF A;  4ETK A;  4JLL A;  1LAP A;  3H8E A;  2FXK A;  3H8F A;  4KYB A;  4ZY2 A;  3IID A;  2L8R A;  3VFQ A;  3H8G A;  3GPO A;  1HJZ A;  5CBM A;  1LAM A;  1YD9 A;  5CB5 A;  2EWB A;  5CMS A;  4JCA A;  1BPM A;  4JGK A;  1SPV A;  2FG1 A;  5FSZ A;  1LAN A;  1GYT A;  3SII A;  3EWP A;  3Q6Z A;  4ZY1 A;  3KR4 A;  5E3B A;  5CB3 A;  1NJR A;  4K0C A;  4K3N A;  4ZX9 A;  1BLL E;  4ZYQ A;  4ABK A;  4D86 A;  4TU0 A;  2J9A A;  3Q71 A;  1LCP A;  3EWR A;  4R6T A;  4ZX8 A;  4R76 A;  1TXZ A;  3EW5 A;  3V2B A;  2BFR A;  3IIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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