2X47A

Crystal structure of human macrod1
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
235
structure length
229
Chain Sequence
TSTDWKEAKSFLKGLSDKQREEHYFCKDFVRLKKIPTWKEMAKGVARYKKDKQLNEKISLLRSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCKTGKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPCEAAAEIVLATLREWLEQHKDKVDRLIICVFLEKDEDIYRSRLPHYFPVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of Macro Domain Proteins as Novel O-Acetyl-Adp-Ribose Deacetylases.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords MACRO DOMAIN-CONTAINING PROTEIN 1
total genus 84
structure length 229
sequence length 235
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 2x47A00
2AFCA 3GPOA 5D8NA 5CB3A 4KSIA 3EWPA 3T8WA 5CBMA 2BFQA 4ZX9A 2FG1A 2EWBA 4R76A 2XD7A 3EWOA 4R6TA 3SIHA 5FSYA 2L8RA 4GUAA 5FSXA 4GVVA 4ZY0A 2FAVA 2ACFA 3V2BA 5CB5A 1ZR3A 1TXZA 4IQYA 4J5RA 1LANA 4GVWA 3GPQA 1LAPA 3VFQA 3EWRA 4R7MA 5HIHA 1NJRA 3EJFA 5HOLA 3KQZA 3SIGA 4ABKA 1YD9A 3IIDA 4JVVA 5FSVA 1LCPA 4JLLA 2X47A 4D86A 1VHUA 4ZYQA 3Q6ZA 3H8FA 4ETJA 1BPMA 4JCAA 4K3NA 3H8EA 4ZY1A 4ETKA 2FXKA 4ZX8A 3KQXA 1HJZA 5CMSA 5DUSA 2LGRA 3EKEA 3GQOA 1SPVA 3EW5A 3V45A 3Q71A 2DX6A 3SIJA 5FSZA 4J4ZA 2J9AA 3EJGA 4TU0A 4ZY2A 4KYBA 4JGKA 4ZI6A 1TY8A 3GQEA 4UMLA 3JRUA 4J5QA 5AILA 1GYTA 1BPNA 3EWQA 3PEIA 3JZTA 1ZR5A 3KZWA 3KR4A 4ESSA 4K0CA 2BFRA 3GPGA 3H8GA 5E3BA 3KR5A 4X2TA 2EEEA 4J5SA 1BLLE 2VRIA 1LAMA 4ABLA 5FSUA 3IJ3A 3SIIA 3ETIA 3IIFA
chains in the Genus database with same CATH superfamily
2AFCA 3GPOA 5D8NA 5CB3A 4KSIA 3EWPA 3T8WA 5CBMA 2BFQA 4ZX9A 2FG1A 2EWBA 4R76A 2XD7A 3EWOA 4R6TA 3SIHA 5FSYA 2L8RA 4GUAA 5FSXA 4GVVA 4ZY0A 2FAVA 2ACFA 3V2BA 2JZFA 5CB5A 1ZR3A 1TXZA 4IQYA 4J5RA 1LANA 2W2GA 4GVWA 1LAPA 3VFQA 3GPQA 3EWRA 4R7MA 5HIHA 1NJRA 3EJFA 5HOLA 3KQZA 3SIGA 2JZEA 1YD9A 4ABKA 3IIDA 4JVVA 5FSVA 1LCPA 4JLLA 2X47A 4D86A 1VHUA 4ZYQA 3Q6ZA 3H8FA 4ETJA 1BPMA 4JCAA 4K3NA 3H8EA 4ZY1A 4ETKA 2FXKA 4ZX8A 3KQXA 1HJZA 5CMSA 2WCTA 5DUSA 2LGRA 3EKEA 3GQOA 1SPVA 3EW5A 3V45A 3Q71A 2DX6A 3SIJA 5FSZA 4J4ZA 2J9AA 3EJGA 4TU0A 4ZY2A 4KYBA 4JGKA 4ZI6A 1TY8A 3GQEA 4UMLA 2KQVA 3JRUA 4J5QA 5AILA 1GYTA 1BPNA 3EWQA 3PEIA 3JZTA 1ZR5A 3KZWA 3KR4A 2RNKA 4ESSA 4K0CA 2BFRA 3GPGA 3H8GA 5E3BA 3KR5A 4X2TA 2EEEA 4J5SA 1BLLE 2VRIA 1LAMA 4ABLA 5FSUA 3IJ3A 2JZDA 3SIIA 3ETIA 3IIFA
chains in the Genus database with same CATH topology
2AFCA 3GPOA 5D8NA 5CB3A 4KSIA 3EWPA 3T8WA 5CBMA 2BFQA 4ZX9A 2FG1A 2EWBA 4R76A 2XD7A 3EWOA 4R6TA 3SIHA 5FSYA 2L8RA 4GUAA 5FSXA 4GVVA 4ZY0A 2FAVA 2ACFA 3V2BA 5CB5A 1ZR3A 1TXZA 4IQYA 4J5RA 1LANA 4GVWA 3GPQA 1LAPA 3VFQA 3EWRA 4R7MA 5HIHA 1NJRA 3EJFA 5HOLA 3KQZA 3SIGA 4ABKA 1YD9A 3IIDA 4JVVA 5FSVA 1LCPA 4JLLA 2X47A 4D86A 1VHUA 4ZYQA 3Q6ZA 3H8FA 4ETJA 1BPMA 4JCAA 4K3NA 3H8EA 4ZY1A 4ETKA 2FXKA 4ZX8A 3KQXA 1HJZA 5CMSA 5DUSA 2LGRA 3EKEA 3GQOA 1SPVA 3EW5A 3V45A 3Q71A 2DX6A 3SIJA 5FSZA 4J4ZA 2J9AA 3EJGA 4TU0A 4ZY2A 4KYBA 4JGKA 4ZI6A 1TY8A 3GQEA 4UMLA 3JRUA 4J5QA 5AILA 1GYTA 1BPNA 3EWQA 3PEIA 3JZTA 1ZR5A 3KZWA 3KR4A 4ESSA 4K0CA 2BFRA 3GPGA 3H8GA 5E3BA 3KR5A 4X2TA 2EEEA 4J5SA 1BLLE 2VRIA 1LAMA 4ABLA 5FSUA 3IJ3A 3SIIA 3ETIA 3IIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AFC A;  3GPO A;  5D8N A;  5CB3 A;  4KSI A;  3EWP A;  3T8W A;  5CBM A;  2BFQ A;  4ZX9 A;  2FG1 A;  2EWB A;  4R76 A;  2XD7 A;  3EWO A;  4R6T A;  3SIH A;  5FSY A;  2L8R A;  4GUA A;  5FSX A;  4GVV A;  4ZY0 A;  2FAV A;  2ACF A;  3V2B A;  5CB5 A;  1ZR3 A;  1TXZ A;  4IQY A;  4J5R A;  1LAN A;  4GVW A;  3GPQ A;  1LAP A;  3VFQ A;  3EWR A;  4R7M A;  5HIH A;  1NJR A;  3EJF A;  5HOL A;  3KQZ A;  3SIG A;  4ABK A;  1YD9 A;  3IID A;  4JVV A;  5FSV A;  1LCP A;  4JLL A;  2X47 A;  4D86 A;  1VHU A;  4ZYQ A;  3Q6Z A;  3H8F A;  4ETJ A;  1BPM A;  4JCA A;  4K3N A;  3H8E A;  4ZY1 A;  4ETK A;  2FXK A;  4ZX8 A;  3KQX A;  1HJZ A;  5CMS A;  5DUS A;  2LGR A;  3EKE A;  3GQO A;  1SPV A;  3EW5 A;  3V45 A;  3Q71 A;  2DX6 A;  3SIJ A;  5FSZ A;  4J4Z A;  2J9A A;  3EJG A;  4TU0 A;  4ZY2 A;  4KYB A;  4JGK A;  4ZI6 A;  1TY8 A;  3GQE A;  4UML A;  3JRU A;  4J5Q A;  5AIL A;  1GYT A;  1BPN A;  3EWQ A;  3PEI A;  3JZT A;  1ZR5 A;  3KZW A;  3KR4 A;  4ESS A;  4K0C A;  2BFR A;  3GPG A;  3H8G A;  5E3B A;  3KR5 A;  4X2T A;  2EEE A;  4J5S A;  1BLL E;  2VRI A;  1LAM A;  4ABL A;  5FSU A;  3IJ3 A;  3SII A;  3ETI A;  3IIF A; 
#chains in the Genus database with same CATH topology
 2AFC A;  3GPO A;  5D8N A;  5CB3 A;  4KSI A;  3EWP A;  3T8W A;  5CBM A;  2BFQ A;  4ZX9 A;  2FG1 A;  2EWB A;  4R76 A;  2XD7 A;  3EWO A;  4R6T A;  3SIH A;  5FSY A;  2L8R A;  4GUA A;  5FSX A;  4GVV A;  4ZY0 A;  2FAV A;  2ACF A;  3V2B A;  2JZF A;  5CB5 A;  1ZR3 A;  1TXZ A;  4IQY A;  4J5R A;  1LAN A;  2W2G A;  4GVW A;  1LAP A;  3VFQ A;  3GPQ A;  3EWR A;  4R7M A;  5HIH A;  1NJR A;  3EJF A;  5HOL A;  3KQZ A;  3SIG A;  2JZE A;  1YD9 A;  4ABK A;  3IID A;  4JVV A;  5FSV A;  1LCP A;  4JLL A;  2X47 A;  4D86 A;  1VHU A;  4ZYQ A;  3Q6Z A;  3H8F A;  4ETJ A;  1BPM A;  4JCA A;  4K3N A;  3H8E A;  4ZY1 A;  4ETK A;  2FXK A;  4ZX8 A;  3KQX A;  1HJZ A;  5CMS A;  2WCT A;  5DUS A;  2LGR A;  3EKE A;  3GQO A;  1SPV A;  3EW5 A;  3V45 A;  3Q71 A;  2DX6 A;  3SIJ A;  5FSZ A;  4J4Z A;  2J9A A;  3EJG A;  4TU0 A;  4ZY2 A;  4KYB A;  4JGK A;  4ZI6 A;  1TY8 A;  3GQE A;  4UML A;  2KQV A;  3JRU A;  4J5Q A;  5AIL A;  1GYT A;  1BPN A;  3EWQ A;  3PEI A;  3JZT A;  1ZR5 A;  3KZW A;  3KR4 A;  2RNK A;  4ESS A;  4K0C A;  2BFR A;  3GPG A;  3H8G A;  5E3B A;  3KR5 A;  4X2T A;  2EEE A;  4J5S A;  1BLL E;  2VRI A;  1LAM A;  4ABL A;  5FSU A;  3IJ3 A;  2JZD A;  3SII A;  3ETI A;  3IIF A; 
#chains in the Genus database with same CATH homology
 2AFC A;  3GPO A;  5D8N A;  5CB3 A;  4KSI A;  3EWP A;  3T8W A;  5CBM A;  2BFQ A;  4ZX9 A;  2FG1 A;  2EWB A;  4R76 A;  2XD7 A;  3EWO A;  4R6T A;  3SIH A;  5FSY A;  2L8R A;  4GUA A;  5FSX A;  4GVV A;  4ZY0 A;  2FAV A;  2ACF A;  3V2B A;  5CB5 A;  1ZR3 A;  1TXZ A;  4IQY A;  4J5R A;  1LAN A;  4GVW A;  3GPQ A;  1LAP A;  3VFQ A;  3EWR A;  4R7M A;  5HIH A;  1NJR A;  3EJF A;  5HOL A;  3KQZ A;  3SIG A;  4ABK A;  1YD9 A;  3IID A;  4JVV A;  5FSV A;  1LCP A;  4JLL A;  2X47 A;  4D86 A;  1VHU A;  4ZYQ A;  3Q6Z A;  3H8F A;  4ETJ A;  1BPM A;  4JCA A;  4K3N A;  3H8E A;  4ZY1 A;  4ETK A;  2FXK A;  4ZX8 A;  3KQX A;  1HJZ A;  5CMS A;  5DUS A;  2LGR A;  3EKE A;  3GQO A;  1SPV A;  3EW5 A;  3V45 A;  3Q71 A;  2DX6 A;  3SIJ A;  5FSZ A;  4J4Z A;  2J9A A;  3EJG A;  4TU0 A;  4ZY2 A;  4KYB A;  4JGK A;  4ZI6 A;  1TY8 A;  3GQE A;  4UML A;  3JRU A;  4J5Q A;  5AIL A;  1GYT A;  1BPN A;  3EWQ A;  3PEI A;  3JZT A;  1ZR5 A;  3KZW A;  3KR4 A;  4ESS A;  4K0C A;  2BFR A;  3GPG A;  3H8G A;  5E3B A;  3KR5 A;  4X2T A;  2EEE A;  4J5S A;  1BLL E;  2VRI A;  1LAM A;  4ABL A;  5FSU A;  3IJ3 A;  3SII A;  3ETI A;  3IIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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