2ACFA

Nmr structure of sars-cov non-structural protein nsp3a (sars1) from sars coronavirus
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
172
structure length
172
Chain Sequence
HHHMPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3.
pubmed doi rcsb
molecule tags Viral protein
source organism Sars coronavirus tor2
molecule keywords Replicase polyprotein 1ab
total genus 62
structure length 172
sequence length 172
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2005-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 2acfA00
4JVVA 2FG1A 3EWQA 3Q6ZA 4R76A 1LAMA 3SIJA 2BFRA 3GQOA 3JRUA 5CB3A 4ZY1A 2FAVA 3IJ3A 2EEEA 5HIHA 1GYTA 3EWOA 3KR5A 2XD7A 3EWRA 4K0CA 3SIGA 4GVVA 1BLLE 3T8WA 3KZWA 4KSIA 1BPMA 5FSZA 4ETKA 4J4ZA 3GQEA 3V45A 1BPNA 1LCPA 3EJGA 5FSUA 4JCAA 1LANA 4ABLA 5FSYA 2J9AA 5D8NA 4R7MA 3ETIA 2ACFA 1TY8A 3H8FA 4ETJA 2VRIA 3EWPA 2FXKA 3EW5A 1VHUA 4X2TA 5HOLA 5CMSA 3EJFA 4K3NA 2L8RA 3GPOA 4TU0A 3SIHA 3JZTA 3SIIA 1LAPA 3GPGA 5DUSA 4ZY2A 4D86A 2EWBA 5AILA 5FSVA 4J5QA 3KQZA 4ZX8A 1ZR5A 1SPVA 1TXZA 1YD9A 4KYBA 3KR4A 5CBMA 1ZR3A 4ZI6A 3IIFA 5E3BA 5FSXA 1NJRA 2DX6A 4UMLA 3Q71A 4GUAA 3PEIA 4IQYA 4ESSA 3GPQA 4ZY0A 4R6TA 3KQXA 3H8EA 4ZYQA 4GVWA 3VFQA 1HJZA 3IIDA 4ZX9A 2BFQA 4JLLA 4J5RA 2AFCA 4J5SA 3V2BA 2LGRA 5CB5A 4ABKA 2X47A 4JGKA 3H8GA 3EKEA
chains in the Genus database with same CATH superfamily
4JVVA 2FG1A 3EWQA 3Q6ZA 2WCTA 4R76A 1LAMA 3SIJA 2JZEA 2BFRA 3GQOA 3JRUA 5CB3A 4ZY1A 2FAVA 3IJ3A 2EEEA 5HIHA 1GYTA 3EWOA 3KR5A 2XD7A 3EWRA 4K0CA 3SIGA 2KQVA 4GVVA 1BLLE 3T8WA 3KZWA 4KSIA 1BPMA 5FSZA 4ETKA 4J4ZA 3GQEA 3V45A 1BPNA 1LCPA 3EJGA 5FSUA 4JCAA 1LANA 4ABLA 5FSYA 2J9AA 5D8NA 4R7MA 3ETIA 2ACFA 1TY8A 2JZFA 3H8FA 4ETJA 2VRIA 3EWPA 2FXKA 3EW5A 1VHUA 2JZDA 4X2TA 5HOLA 5CMSA 3EJFA 4K3NA 2L8RA 3GPOA 4TU0A 3SIHA 3JZTA 3SIIA 1LAPA 3GPGA 5DUSA 4ZY2A 4D86A 2EWBA 5AILA 5FSVA 4J5QA 3KQZA 4ZX8A 1ZR5A 1SPVA 1TXZA 1YD9A 4KYBA 3KR4A 5CBMA 1ZR3A 4ZI6A 3IIFA 5E3BA 5FSXA 1NJRA 2DX6A 4UMLA 3Q71A 4GUAA 3PEIA 4IQYA 4ESSA 3GPQA 4ZY0A 4R6TA 3KQXA 3H8EA 2RNKA 4ZYQA 4GVWA 3VFQA 1HJZA 3IIDA 4ZX9A 2BFQA 2W2GA 4JLLA 4J5RA 2AFCA 4J5SA 3V2BA 2LGRA 5CB5A 4ABKA 2X47A 4JGKA 3H8GA 3EKEA
chains in the Genus database with same CATH topology
4JVVA 2FG1A 3EWQA 3Q6ZA 4R76A 1LAMA 3SIJA 2BFRA 3GQOA 3JRUA 5CB3A 4ZY1A 2FAVA 3IJ3A 2EEEA 5HIHA 1GYTA 3EWOA 3KR5A 2XD7A 3EWRA 4K0CA 3SIGA 4GVVA 1BLLE 3T8WA 3KZWA 4KSIA 1BPMA 5FSZA 4ETKA 4J4ZA 3GQEA 3V45A 1BPNA 1LCPA 3EJGA 5FSUA 4JCAA 1LANA 4ABLA 5FSYA 2J9AA 5D8NA 4R7MA 3ETIA 2ACFA 1TY8A 3H8FA 4ETJA 2VRIA 3EWPA 2FXKA 3EW5A 1VHUA 4X2TA 5HOLA 5CMSA 3EJFA 4K3NA 2L8RA 3GPOA 4TU0A 3SIHA 3JZTA 3SIIA 1LAPA 3GPGA 5DUSA 4ZY2A 4D86A 2EWBA 5AILA 5FSVA 4J5QA 3KQZA 4ZX8A 1ZR5A 1SPVA 1TXZA 1YD9A 4KYBA 3KR4A 5CBMA 1ZR3A 4ZI6A 3IIFA 5E3BA 5FSXA 1NJRA 2DX6A 4UMLA 3Q71A 4GUAA 3PEIA 4IQYA 4ESSA 3GPQA 4ZY0A 4R6TA 3KQXA 3H8EA 4ZYQA 4GVWA 3VFQA 1HJZA 3IIDA 4ZX9A 2BFQA 4JLLA 4J5RA 2AFCA 4J5SA 3V2BA 2LGRA 5CB5A 4ABKA 2X47A 4JGKA 3H8GA 3EKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JVV A;  2FG1 A;  3EWQ A;  3Q6Z A;  4R76 A;  1LAM A;  3SIJ A;  2BFR A;  3GQO A;  3JRU A;  5CB3 A;  4ZY1 A;  2FAV A;  3IJ3 A;  2EEE A;  5HIH A;  1GYT A;  3EWO A;  3KR5 A;  2XD7 A;  3EWR A;  4K0C A;  3SIG A;  4GVV A;  1BLL E;  3T8W A;  3KZW A;  4KSI A;  1BPM A;  5FSZ A;  4ETK A;  4J4Z A;  3GQE A;  3V45 A;  1BPN A;  1LCP A;  3EJG A;  5FSU A;  4JCA A;  1LAN A;  4ABL A;  5FSY A;  2J9A A;  5D8N A;  4R7M A;  3ETI A;  2ACF A;  1TY8 A;  3H8F A;  4ETJ A;  2VRI A;  3EWP A;  2FXK A;  3EW5 A;  1VHU A;  4X2T A;  5HOL A;  5CMS A;  3EJF A;  4K3N A;  2L8R A;  3GPO A;  4TU0 A;  3SIH A;  3JZT A;  3SII A;  1LAP A;  3GPG A;  5DUS A;  4ZY2 A;  4D86 A;  2EWB A;  5AIL A;  5FSV A;  4J5Q A;  3KQZ A;  4ZX8 A;  1ZR5 A;  1SPV A;  1TXZ A;  1YD9 A;  4KYB A;  3KR4 A;  5CBM A;  1ZR3 A;  4ZI6 A;  3IIF A;  5E3B A;  5FSX A;  1NJR A;  2DX6 A;  4UML A;  3Q71 A;  4GUA A;  3PEI A;  4IQY A;  4ESS A;  3GPQ A;  4ZY0 A;  4R6T A;  3KQX A;  3H8E A;  4ZYQ A;  4GVW A;  3VFQ A;  1HJZ A;  3IID A;  4ZX9 A;  2BFQ A;  4JLL A;  4J5R A;  2AFC A;  4J5S A;  3V2B A;  2LGR A;  5CB5 A;  4ABK A;  2X47 A;  4JGK A;  3H8G A;  3EKE A; 
#chains in the Genus database with same CATH topology
 4JVV A;  2FG1 A;  3EWQ A;  3Q6Z A;  2WCT A;  4R76 A;  1LAM A;  3SIJ A;  2JZE A;  2BFR A;  3GQO A;  3JRU A;  5CB3 A;  4ZY1 A;  2FAV A;  3IJ3 A;  2EEE A;  5HIH A;  1GYT A;  3EWO A;  3KR5 A;  2XD7 A;  3EWR A;  4K0C A;  3SIG A;  2KQV A;  4GVV A;  1BLL E;  3T8W A;  3KZW A;  4KSI A;  1BPM A;  5FSZ A;  4ETK A;  4J4Z A;  3GQE A;  3V45 A;  1BPN A;  1LCP A;  3EJG A;  5FSU A;  4JCA A;  1LAN A;  4ABL A;  5FSY A;  2J9A A;  5D8N A;  4R7M A;  3ETI A;  2ACF A;  1TY8 A;  2JZF A;  3H8F A;  4ETJ A;  2VRI A;  3EWP A;  2FXK A;  3EW5 A;  1VHU A;  2JZD A;  4X2T A;  5HOL A;  5CMS A;  3EJF A;  4K3N A;  2L8R A;  3GPO A;  4TU0 A;  3SIH A;  3JZT A;  3SII A;  1LAP A;  3GPG A;  5DUS A;  4ZY2 A;  4D86 A;  2EWB A;  5AIL A;  5FSV A;  4J5Q A;  3KQZ A;  4ZX8 A;  1ZR5 A;  1SPV A;  1TXZ A;  1YD9 A;  4KYB A;  3KR4 A;  5CBM A;  1ZR3 A;  4ZI6 A;  3IIF A;  5E3B A;  5FSX A;  1NJR A;  2DX6 A;  4UML A;  3Q71 A;  4GUA A;  3PEI A;  4IQY A;  4ESS A;  3GPQ A;  4ZY0 A;  4R6T A;  3KQX A;  3H8E A;  2RNK A;  4ZYQ A;  4GVW A;  3VFQ A;  1HJZ A;  3IID A;  4ZX9 A;  2BFQ A;  2W2G A;  4JLL A;  4J5R A;  2AFC A;  4J5S A;  3V2B A;  2LGR A;  5CB5 A;  4ABK A;  2X47 A;  4JGK A;  3H8G A;  3EKE A; 
#chains in the Genus database with same CATH homology
 4JVV A;  2FG1 A;  3EWQ A;  3Q6Z A;  4R76 A;  1LAM A;  3SIJ A;  2BFR A;  3GQO A;  3JRU A;  5CB3 A;  4ZY1 A;  2FAV A;  3IJ3 A;  2EEE A;  5HIH A;  1GYT A;  3EWO A;  3KR5 A;  2XD7 A;  3EWR A;  4K0C A;  3SIG A;  4GVV A;  1BLL E;  3T8W A;  3KZW A;  4KSI A;  1BPM A;  5FSZ A;  4ETK A;  4J4Z A;  3GQE A;  3V45 A;  1BPN A;  1LCP A;  3EJG A;  5FSU A;  4JCA A;  1LAN A;  4ABL A;  5FSY A;  2J9A A;  5D8N A;  4R7M A;  3ETI A;  2ACF A;  1TY8 A;  3H8F A;  4ETJ A;  2VRI A;  3EWP A;  2FXK A;  3EW5 A;  1VHU A;  4X2T A;  5HOL A;  5CMS A;  3EJF A;  4K3N A;  2L8R A;  3GPO A;  4TU0 A;  3SIH A;  3JZT A;  3SII A;  1LAP A;  3GPG A;  5DUS A;  4ZY2 A;  4D86 A;  2EWB A;  5AIL A;  5FSV A;  4J5Q A;  3KQZ A;  4ZX8 A;  1ZR5 A;  1SPV A;  1TXZ A;  1YD9 A;  4KYB A;  3KR4 A;  5CBM A;  1ZR3 A;  4ZI6 A;  3IIF A;  5E3B A;  5FSX A;  1NJR A;  2DX6 A;  4UML A;  3Q71 A;  4GUA A;  3PEI A;  4IQY A;  4ESS A;  3GPQ A;  4ZY0 A;  4R6T A;  3KQX A;  3H8E A;  4ZYQ A;  4GVW A;  3VFQ A;  1HJZ A;  3IID A;  4ZX9 A;  2BFQ A;  4JLL A;  4J5R A;  2AFC A;  4J5S A;  3V2B A;  2LGR A;  5CB5 A;  4ABK A;  2X47 A;  4JGK A;  3H8G A;  3EKE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...