3GPQA

Crystal structure of macro domain of chikungunya virus in complex with rna
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
160
structure length
160
Chain Sequence
APSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
pubmed doi rcsb
molecule tags Viral protein/rna
source organism Chikungunya virus
molecule keywords Non-structural protein 3
total genus 50
structure length 160
sequence length 160
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3gpqA00
2BFRA 4J5SA 5FSUA 2EEEA 2FAVA 4ZX8A 4TU0A 4ETKA 3Q71A 5CB5A 2LGRA 4IQYA 5FSXA 3EJFA 3SIGA 3H8FA 4K0CA 1BPNA 4ABKA 3KZWA 1YD9A 3T8WA 4K3NA 1TXZA 3SIJA 3KQXA 3GQEA 2J9AA 2X47A 1ZR5A 4J5RA 4GUAA 3JRUA 3V45A 1LCPA 3KR4A 3Q6ZA 1GYTA 1LAMA 2ACFA 4KYBA 3IIFA 4R6TA 3IJ3A 3VFQA 3EJGA 4GVWA 5DUSA 3V2BA 4J5QA 2EWBA 4JVVA 4ZY2A 3GPOA 5HOLA 2XD7A 4X2TA 5HIHA 1TY8A 4ETJA 2L8RA 1BPMA 4KSIA 5FSZA 5FSVA 4JLLA 5CB3A 3ETIA 2VRIA 3PEIA 1VHUA 4UMLA 2DX6A 5D8NA 2BFQA 3EWQA 2FXKA 3GQOA 3H8GA 4ABLA 3KR5A 4ZYQA 1NJRA 4ZY1A 4ESSA 4R7MA 5AILA 1ZR3A 4R76A 4GVVA 3H8EA 3JZTA 3GPQA 3EWOA 4JCAA 3GPGA 3SIIA 1SPVA 5CMSA 4ZX9A 3EWRA 3KQZA 3EW5A 5CBMA 1LAPA 4JGKA 1HJZA 3EKEA 1BLLE 5E3BA 4D86A 1LANA 5FSYA 3EWPA 4ZI6A 4J4ZA 2AFCA 3IIDA 2FG1A 3SIHA 4ZY0A
chains in the Genus database with same CATH superfamily
2BFRA 4J5SA 5FSUA 2EEEA 2FAVA 4ZX8A 4TU0A 4ETKA 3Q71A 5CB5A 2LGRA 4IQYA 5FSXA 3EJFA 3SIGA 3H8FA 4K0CA 1BPNA 4ABKA 3KZWA 1YD9A 3T8WA 4K3NA 1TXZA 3SIJA 3KQXA 3GQEA 2J9AA 2X47A 1ZR5A 2JZFA 4J5RA 4GUAA 3JRUA 3V45A 1LCPA 3KR4A 3Q6ZA 2JZDA 1GYTA 1LAMA 2ACFA 4KYBA 3IIFA 4R6TA 3IJ3A 3VFQA 3EJGA 4GVWA 5DUSA 3V2BA 4J5QA 2RNKA 2WCTA 2EWBA 4JVVA 4ZY2A 3GPOA 5HOLA 2XD7A 4X2TA 5HIHA 1TY8A 4ETJA 2L8RA 1BPMA 4KSIA 5FSZA 5FSVA 4JLLA 5CB3A 3ETIA 2VRIA 3PEIA 1VHUA 4UMLA 2DX6A 5D8NA 2BFQA 3EWQA 2FXKA 3GQOA 3H8GA 4ABLA 3KR5A 4ZYQA 1NJRA 4ZY1A 4ESSA 2JZEA 4R7MA 5AILA 1ZR3A 4R76A 4GVVA 3H8EA 3JZTA 3GPQA 2W2GA 3EWOA 4JCAA 3GPGA 3SIIA 1SPVA 5CMSA 4ZX9A 2KQVA 3EWRA 3KQZA 3EW5A 5CBMA 1LAPA 4JGKA 1HJZA 3EKEA 1BLLE 5E3BA 4D86A 1LANA 5FSYA 3EWPA 4ZI6A 4J4ZA 2AFCA 3IIDA 2FG1A 3SIHA 4ZY0A
chains in the Genus database with same CATH topology
2BFRA 4J5SA 5FSUA 2EEEA 2FAVA 4ZX8A 4TU0A 4ETKA 3Q71A 5CB5A 2LGRA 4IQYA 5FSXA 3EJFA 3SIGA 3H8FA 4K0CA 1BPNA 4ABKA 3KZWA 1YD9A 3T8WA 4K3NA 1TXZA 3SIJA 3KQXA 3GQEA 2J9AA 2X47A 1ZR5A 4J5RA 4GUAA 3JRUA 3V45A 1LCPA 3KR4A 3Q6ZA 1GYTA 1LAMA 2ACFA 4KYBA 3IIFA 4R6TA 3IJ3A 3VFQA 3EJGA 4GVWA 5DUSA 3V2BA 4J5QA 2EWBA 4JVVA 4ZY2A 3GPOA 5HOLA 2XD7A 4X2TA 5HIHA 1TY8A 4ETJA 2L8RA 1BPMA 4KSIA 5FSZA 5FSVA 4JLLA 5CB3A 3ETIA 2VRIA 3PEIA 1VHUA 4UMLA 2DX6A 5D8NA 2BFQA 3EWQA 2FXKA 3GQOA 3H8GA 4ABLA 3KR5A 4ZYQA 1NJRA 4ZY1A 4ESSA 4R7MA 5AILA 1ZR3A 4R76A 4GVVA 3H8EA 3JZTA 3GPQA 3EWOA 4JCAA 3GPGA 3SIIA 1SPVA 5CMSA 4ZX9A 3EWRA 3KQZA 3EW5A 5CBMA 1LAPA 4JGKA 1HJZA 3EKEA 1BLLE 5E3BA 4D86A 1LANA 5FSYA 3EWPA 4ZI6A 4J4ZA 2AFCA 3IIDA 2FG1A 3SIHA 4ZY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BFR A;  4J5S A;  5FSU A;  2EEE A;  2FAV A;  4ZX8 A;  4TU0 A;  4ETK A;  3Q71 A;  5CB5 A;  2LGR A;  4IQY A;  5FSX A;  3EJF A;  3SIG A;  3H8F A;  4K0C A;  1BPN A;  4ABK A;  3KZW A;  1YD9 A;  3T8W A;  4K3N A;  1TXZ A;  3SIJ A;  3KQX A;  3GQE A;  2J9A A;  2X47 A;  1ZR5 A;  4J5R A;  4GUA A;  3JRU A;  3V45 A;  1LCP A;  3KR4 A;  3Q6Z A;  1GYT A;  1LAM A;  2ACF A;  4KYB A;  3IIF A;  4R6T A;  3IJ3 A;  3VFQ A;  3EJG A;  4GVW A;  5DUS A;  3V2B A;  4J5Q A;  2EWB A;  4JVV A;  4ZY2 A;  3GPO A;  5HOL A;  2XD7 A;  4X2T A;  5HIH A;  1TY8 A;  4ETJ A;  2L8R A;  1BPM A;  4KSI A;  5FSZ A;  5FSV A;  4JLL A;  5CB3 A;  3ETI A;  2VRI A;  3PEI A;  1VHU A;  4UML A;  2DX6 A;  5D8N A;  2BFQ A;  3EWQ A;  2FXK A;  3GQO A;  3H8G A;  4ABL A;  3KR5 A;  4ZYQ A;  1NJR A;  4ZY1 A;  4ESS A;  4R7M A;  5AIL A;  1ZR3 A;  4R76 A;  4GVV A;  3H8E A;  3JZT A;  3GPQ A;  3EWO A;  4JCA A;  3GPG A;  3SII A;  1SPV A;  5CMS A;  4ZX9 A;  3EWR A;  3KQZ A;  3EW5 A;  5CBM A;  1LAP A;  4JGK A;  1HJZ A;  3EKE A;  1BLL E;  5E3B A;  4D86 A;  1LAN A;  5FSY A;  3EWP A;  4ZI6 A;  4J4Z A;  2AFC A;  3IID A;  2FG1 A;  3SIH A;  4ZY0 A; 
#chains in the Genus database with same CATH topology
 2BFR A;  4J5S A;  5FSU A;  2EEE A;  2FAV A;  4ZX8 A;  4TU0 A;  4ETK A;  3Q71 A;  5CB5 A;  2LGR A;  4IQY A;  5FSX A;  3EJF A;  3SIG A;  3H8F A;  4K0C A;  1BPN A;  4ABK A;  3KZW A;  1YD9 A;  3T8W A;  4K3N A;  1TXZ A;  3SIJ A;  3KQX A;  3GQE A;  2J9A A;  2X47 A;  1ZR5 A;  2JZF A;  4J5R A;  4GUA A;  3JRU A;  3V45 A;  1LCP A;  3KR4 A;  3Q6Z A;  2JZD A;  1GYT A;  1LAM A;  2ACF A;  4KYB A;  3IIF A;  4R6T A;  3IJ3 A;  3VFQ A;  3EJG A;  4GVW A;  5DUS A;  3V2B A;  4J5Q A;  2RNK A;  2WCT A;  2EWB A;  4JVV A;  4ZY2 A;  3GPO A;  5HOL A;  2XD7 A;  4X2T A;  5HIH A;  1TY8 A;  4ETJ A;  2L8R A;  1BPM A;  4KSI A;  5FSZ A;  5FSV A;  4JLL A;  5CB3 A;  3ETI A;  2VRI A;  3PEI A;  1VHU A;  4UML A;  2DX6 A;  5D8N A;  2BFQ A;  3EWQ A;  2FXK A;  3GQO A;  3H8G A;  4ABL A;  3KR5 A;  4ZYQ A;  1NJR A;  4ZY1 A;  4ESS A;  2JZE A;  4R7M A;  5AIL A;  1ZR3 A;  4R76 A;  4GVV A;  3H8E A;  3JZT A;  3GPQ A;  2W2G A;  3EWO A;  4JCA A;  3GPG A;  3SII A;  1SPV A;  5CMS A;  4ZX9 A;  2KQV A;  3EWR A;  3KQZ A;  3EW5 A;  5CBM A;  1LAP A;  4JGK A;  1HJZ A;  3EKE A;  1BLL E;  5E3B A;  4D86 A;  1LAN A;  5FSY A;  3EWP A;  4ZI6 A;  4J4Z A;  2AFC A;  3IID A;  2FG1 A;  3SIH A;  4ZY0 A; 
#chains in the Genus database with same CATH homology
 2BFR A;  4J5S A;  5FSU A;  2EEE A;  2FAV A;  4ZX8 A;  4TU0 A;  4ETK A;  3Q71 A;  5CB5 A;  2LGR A;  4IQY A;  5FSX A;  3EJF A;  3SIG A;  3H8F A;  4K0C A;  1BPN A;  4ABK A;  3KZW A;  1YD9 A;  3T8W A;  4K3N A;  1TXZ A;  3SIJ A;  3KQX A;  3GQE A;  2J9A A;  2X47 A;  1ZR5 A;  4J5R A;  4GUA A;  3JRU A;  3V45 A;  1LCP A;  3KR4 A;  3Q6Z A;  1GYT A;  1LAM A;  2ACF A;  4KYB A;  3IIF A;  4R6T A;  3IJ3 A;  3VFQ A;  3EJG A;  4GVW A;  5DUS A;  3V2B A;  4J5Q A;  2EWB A;  4JVV A;  4ZY2 A;  3GPO A;  5HOL A;  2XD7 A;  4X2T A;  5HIH A;  1TY8 A;  4ETJ A;  2L8R A;  1BPM A;  4KSI A;  5FSZ A;  5FSV A;  4JLL A;  5CB3 A;  3ETI A;  2VRI A;  3PEI A;  1VHU A;  4UML A;  2DX6 A;  5D8N A;  2BFQ A;  3EWQ A;  2FXK A;  3GQO A;  3H8G A;  4ABL A;  3KR5 A;  4ZYQ A;  1NJR A;  4ZY1 A;  4ESS A;  4R7M A;  5AIL A;  1ZR3 A;  4R76 A;  4GVV A;  3H8E A;  3JZT A;  3GPQ A;  3EWO A;  4JCA A;  3GPG A;  3SII A;  1SPV A;  5CMS A;  4ZX9 A;  3EWR A;  3KQZ A;  3EW5 A;  5CBM A;  1LAP A;  4JGK A;  1HJZ A;  3EKE A;  1BLL E;  5E3B A;  4D86 A;  1LAN A;  5FSY A;  3EWP A;  4ZI6 A;  4J4Z A;  2AFC A;  3IID A;  2FG1 A;  3SIH A;  4ZY0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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