3IIDA

Crystal structure of the macro domain of human histone macroh2a1.1 in complex with adp-ribose (form a)
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
185
structure length
185
Chain Sequence
ADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
pubmed doi rcsb
molecule tags Gene regulation
source organism Homo sapiens
molecule keywords Core histone macro-H2A.1, Isoform 1
total genus 62
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2009-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3iidA00
3GPOA 2VRIA 3KZWA 2ACFA 3GQOA 4J4ZA 1TXZA 4ZX9A 1LAPA 1ZR5A 2XD7A 4ZI6A 2X47A 5AILA 4ZY1A 1ZR3A 4JVVA 3VFQA 5CB3A 3EWOA 3Q6ZA 4IQYA 2FXKA 3EJGA 2DX6A 2FAVA 3SIHA 3T8WA 3H8EA 5CMSA 1HJZA 5CB5A 1LANA 4ABLA 3H8GA 4K3NA 3GPGA 4J5RA 3PEIA 3H8FA 4ABKA 3KR4A 3V45A 4ZY0A 1BPMA 3EW5A 5FSUA 5FSVA 1VHUA 3EWRA 1TY8A 4X2TA 1NJRA 3SIIA 5D8NA 4D86A 3EKEA 3KQXA 4ZYQA 2BFRA 4UMLA 1BPNA 2L8RA 2EWBA 3ETIA 2EEEA 5HOLA 1LCPA 5FSZA 3KR5A 4R7MA 2J9AA 2LGRA 4R76A 3EWQA 3KQZA 4ZY2A 4ETJA 4J5SA 3Q71A 4JCAA 3SIGA 5CBMA 1GYTA 2AFCA 5E3BA 4ZX8A 4K0CA 4GVVA 4R6TA 4KSIA 4GVWA 5FSXA 4GUAA 4J5QA 4ESSA 3JZTA 4KYBA 1BLLE 3EWPA 3IJ3A 5FSYA 4ETKA 1LAMA 3EJFA 2BFQA 1SPVA 2FG1A 3IIDA 3GPQA 5HIHA 4JLLA 3V2BA 1YD9A 3JRUA 3SIJA 5DUSA 4TU0A 4JGKA 3IIFA 3GQEA
chains in the Genus database with same CATH superfamily
3GPOA 2VRIA 3KZWA 2ACFA 3GQOA 4J4ZA 1TXZA 4ZX9A 1LAPA 1ZR5A 2XD7A 4ZI6A 2X47A 5AILA 4ZY1A 1ZR3A 4JVVA 3VFQA 5CB3A 3EWOA 3Q6ZA 4IQYA 2FXKA 3EJGA 2DX6A 2JZFA 2FAVA 3SIHA 2KQVA 3T8WA 3H8EA 5CMSA 1HJZA 5CB5A 1LANA 4ABLA 3H8GA 4K3NA 3GPGA 4J5RA 3PEIA 3H8FA 4ABKA 3KR4A 3V45A 4ZY0A 1BPMA 3EW5A 5FSUA 5FSVA 1VHUA 3EWRA 1TY8A 4X2TA 1NJRA 2JZEA 3SIIA 5D8NA 4D86A 3EKEA 3KQXA 4ZYQA 2BFRA 4UMLA 1BPNA 2L8RA 2EWBA 3ETIA 2EEEA 5HOLA 1LCPA 5FSZA 3KR5A 4R7MA 2WCTA 2J9AA 2LGRA 4R76A 3EWQA 3KQZA 4ZY2A 4ETJA 4J5SA 3Q71A 4JCAA 3SIGA 5CBMA 1GYTA 2AFCA 5E3BA 4ZX8A 4K0CA 4GVVA 2JZDA 4R6TA 4KSIA 4GVWA 5FSXA 4GUAA 4J5QA 4ESSA 3JZTA 4KYBA 1BLLE 3EWPA 3IJ3A 5FSYA 2W2GA 4ETKA 1LAMA 3EJFA 2BFQA 1SPVA 2FG1A 3IIDA 3GPQA 5HIHA 4JLLA 3V2BA 1YD9A 2RNKA 3JRUA 3SIJA 5DUSA 4TU0A 4JGKA 3IIFA 3GQEA
chains in the Genus database with same CATH topology
3GPOA 2VRIA 3KZWA 2ACFA 3GQOA 4J4ZA 1TXZA 4ZX9A 1LAPA 1ZR5A 2XD7A 4ZI6A 2X47A 5AILA 4ZY1A 1ZR3A 4JVVA 3VFQA 5CB3A 3EWOA 3Q6ZA 4IQYA 2FXKA 3EJGA 2DX6A 2FAVA 3SIHA 3T8WA 3H8EA 5CMSA 1HJZA 5CB5A 1LANA 4ABLA 3H8GA 4K3NA 3GPGA 4J5RA 3PEIA 3H8FA 4ABKA 3KR4A 3V45A 4ZY0A 1BPMA 3EW5A 5FSUA 5FSVA 1VHUA 3EWRA 1TY8A 4X2TA 1NJRA 3SIIA 5D8NA 4D86A 3EKEA 3KQXA 4ZYQA 2BFRA 4UMLA 1BPNA 2L8RA 2EWBA 3ETIA 2EEEA 5HOLA 1LCPA 5FSZA 3KR5A 4R7MA 2J9AA 2LGRA 4R76A 3EWQA 3KQZA 4ZY2A 4ETJA 4J5SA 3Q71A 4JCAA 3SIGA 5CBMA 1GYTA 2AFCA 5E3BA 4ZX8A 4K0CA 4GVVA 4R6TA 4KSIA 4GVWA 5FSXA 4GUAA 4J5QA 4ESSA 3JZTA 4KYBA 1BLLE 3EWPA 3IJ3A 5FSYA 4ETKA 1LAMA 3EJFA 2BFQA 1SPVA 2FG1A 3IIDA 3GPQA 5HIHA 4JLLA 3V2BA 1YD9A 3JRUA 3SIJA 5DUSA 4TU0A 4JGKA 3IIFA 3GQEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GPO A;  2VRI A;  3KZW A;  2ACF A;  3GQO A;  4J4Z A;  1TXZ A;  4ZX9 A;  1LAP A;  1ZR5 A;  2XD7 A;  4ZI6 A;  2X47 A;  5AIL A;  4ZY1 A;  1ZR3 A;  4JVV A;  3VFQ A;  5CB3 A;  3EWO A;  3Q6Z A;  4IQY A;  2FXK A;  3EJG A;  2DX6 A;  2FAV A;  3SIH A;  3T8W A;  3H8E A;  5CMS A;  1HJZ A;  5CB5 A;  1LAN A;  4ABL A;  3H8G A;  4K3N A;  3GPG A;  4J5R A;  3PEI A;  3H8F A;  4ABK A;  3KR4 A;  3V45 A;  4ZY0 A;  1BPM A;  3EW5 A;  5FSU A;  5FSV A;  1VHU A;  3EWR A;  1TY8 A;  4X2T A;  1NJR A;  3SII A;  5D8N A;  4D86 A;  3EKE A;  3KQX A;  4ZYQ A;  2BFR A;  4UML A;  1BPN A;  2L8R A;  2EWB A;  3ETI A;  2EEE A;  5HOL A;  1LCP A;  5FSZ A;  3KR5 A;  4R7M A;  2J9A A;  2LGR A;  4R76 A;  3EWQ A;  3KQZ A;  4ZY2 A;  4ETJ A;  4J5S A;  3Q71 A;  4JCA A;  3SIG A;  5CBM A;  1GYT A;  2AFC A;  5E3B A;  4ZX8 A;  4K0C A;  4GVV A;  4R6T A;  4KSI A;  4GVW A;  5FSX A;  4GUA A;  4J5Q A;  4ESS A;  3JZT A;  4KYB A;  1BLL E;  3EWP A;  3IJ3 A;  5FSY A;  4ETK A;  1LAM A;  3EJF A;  2BFQ A;  1SPV A;  2FG1 A;  3IID A;  3GPQ A;  5HIH A;  4JLL A;  3V2B A;  1YD9 A;  3JRU A;  3SIJ A;  5DUS A;  4TU0 A;  4JGK A;  3IIF A;  3GQE A; 
#chains in the Genus database with same CATH topology
 3GPO A;  2VRI A;  3KZW A;  2ACF A;  3GQO A;  4J4Z A;  1TXZ A;  4ZX9 A;  1LAP A;  1ZR5 A;  2XD7 A;  4ZI6 A;  2X47 A;  5AIL A;  4ZY1 A;  1ZR3 A;  4JVV A;  3VFQ A;  5CB3 A;  3EWO A;  3Q6Z A;  4IQY A;  2FXK A;  3EJG A;  2DX6 A;  2JZF A;  2FAV A;  3SIH A;  2KQV A;  3T8W A;  3H8E A;  5CMS A;  1HJZ A;  5CB5 A;  1LAN A;  4ABL A;  3H8G A;  4K3N A;  3GPG A;  4J5R A;  3PEI A;  3H8F A;  4ABK A;  3KR4 A;  3V45 A;  4ZY0 A;  1BPM A;  3EW5 A;  5FSU A;  5FSV A;  1VHU A;  3EWR A;  1TY8 A;  4X2T A;  1NJR A;  2JZE A;  3SII A;  5D8N A;  4D86 A;  3EKE A;  3KQX A;  4ZYQ A;  2BFR A;  4UML A;  1BPN A;  2L8R A;  2EWB A;  3ETI A;  2EEE A;  5HOL A;  1LCP A;  5FSZ A;  3KR5 A;  4R7M A;  2WCT A;  2J9A A;  2LGR A;  4R76 A;  3EWQ A;  3KQZ A;  4ZY2 A;  4ETJ A;  4J5S A;  3Q71 A;  4JCA A;  3SIG A;  5CBM A;  1GYT A;  2AFC A;  5E3B A;  4ZX8 A;  4K0C A;  4GVV A;  2JZD A;  4R6T A;  4KSI A;  4GVW A;  5FSX A;  4GUA A;  4J5Q A;  4ESS A;  3JZT A;  4KYB A;  1BLL E;  3EWP A;  3IJ3 A;  5FSY A;  2W2G A;  4ETK A;  1LAM A;  3EJF A;  2BFQ A;  1SPV A;  2FG1 A;  3IID A;  3GPQ A;  5HIH A;  4JLL A;  3V2B A;  1YD9 A;  2RNK A;  3JRU A;  3SIJ A;  5DUS A;  4TU0 A;  4JGK A;  3IIF A;  3GQE A; 
#chains in the Genus database with same CATH homology
 3GPO A;  2VRI A;  3KZW A;  2ACF A;  3GQO A;  4J4Z A;  1TXZ A;  4ZX9 A;  1LAP A;  1ZR5 A;  2XD7 A;  4ZI6 A;  2X47 A;  5AIL A;  4ZY1 A;  1ZR3 A;  4JVV A;  3VFQ A;  5CB3 A;  3EWO A;  3Q6Z A;  4IQY A;  2FXK A;  3EJG A;  2DX6 A;  2FAV A;  3SIH A;  3T8W A;  3H8E A;  5CMS A;  1HJZ A;  5CB5 A;  1LAN A;  4ABL A;  3H8G A;  4K3N A;  3GPG A;  4J5R A;  3PEI A;  3H8F A;  4ABK A;  3KR4 A;  3V45 A;  4ZY0 A;  1BPM A;  3EW5 A;  5FSU A;  5FSV A;  1VHU A;  3EWR A;  1TY8 A;  4X2T A;  1NJR A;  3SII A;  5D8N A;  4D86 A;  3EKE A;  3KQX A;  4ZYQ A;  2BFR A;  4UML A;  1BPN A;  2L8R A;  2EWB A;  3ETI A;  2EEE A;  5HOL A;  1LCP A;  5FSZ A;  3KR5 A;  4R7M A;  2J9A A;  2LGR A;  4R76 A;  3EWQ A;  3KQZ A;  4ZY2 A;  4ETJ A;  4J5S A;  3Q71 A;  4JCA A;  3SIG A;  5CBM A;  1GYT A;  2AFC A;  5E3B A;  4ZX8 A;  4K0C A;  4GVV A;  4R6T A;  4KSI A;  4GVW A;  5FSX A;  4GUA A;  4J5Q A;  4ESS A;  3JZT A;  4KYB A;  1BLL E;  3EWP A;  3IJ3 A;  5FSY A;  4ETK A;  1LAM A;  3EJF A;  2BFQ A;  1SPV A;  2FG1 A;  3IID A;  3GPQ A;  5HIH A;  4JLL A;  3V2B A;  1YD9 A;  3JRU A;  3SIJ A;  5DUS A;  4TU0 A;  4JGK A;  3IIF A;  3GQE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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