3SIHA

The x-ray crystal structure of poly(adp-ribose) glycohydrolase (parg) from thermomonospora curvata
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
274
structure length
274
Chain Sequence
RHSRRAIAAETVEILERGRYTAPSGRVVPIADHVAQAVRGTRLYRPEKLAVLLEGLGAASDGAPTRIEVTEETTLAAARRLTGAAGDQVACLNFASAEHPGGGFLSGAHAQEEGLARSSGLYASLRAVPQFYAFHHRQRDPLYSDHLIYSPGVPVFRDDAGRLLEEPYRVAFLTSPAPNRRAIGDLRTVEEIGRVLRGRAAKVLAAARHHGHRRLVLGAWGCGVFGNDPAQVAETFAGLLLDGGPFAGRFAHVVFAVWDTAPGAPRHAAFARRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermomonospora curvata
molecule keywords poly(ADP-ribose) glycohydrolase
total genus 94
structure length 274
sequence length 274
ec nomenclature ec 3.2.1.143: Poly(ADP-ribose) glycohydrolase.
pdb deposition date 2011-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10021 DUF2263 Uncharacterized protein conserved in bacteria (DUF2263)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3sihA00
4ZX8A 3EWOA 3H8FA 2FAVA 5FSYA 2AFCA 4JVVA 4ZY2A 4ABKA 4ZY1A 5FSVA 5CMSA 3KR5A 1BPNA 2ACFA 3SIGA 3Q6ZA 4ZY0A 3JRUA 3KQXA 4GVVA 4JCAA 4UMLA 3H8EA 3SIJA 5E3BA 2VRIA 4J5QA 4J5SA 4KSIA 3IIFA 3GPQA 1BPMA 5D8NA 2J9AA 4ABLA 3EW5A 3KQZA 1ZR5A 3GPGA 4K0CA 5FSXA 1ZR3A 4TU0A 2L8RA 4R7MA 5HOLA 2EWBA 1YD9A 2BFRA 4X2TA 5HIHA 1HJZA 2LGRA 1TXZA 2FG1A 5DUSA 4JGKA 3T8WA 3EWPA 5CB3A 4GVWA 4ZYQA 4ZI6A 4JLLA 5CB5A 1LCPA 3GQEA 4R6TA 4R76A 3SIIA 2FXKA 2X47A 3KR4A 3IJ3A 4D86A 1GYTA 2EEEA 4GUAA 1VHUA 2BFQA 3KZWA 1LAMA 5FSZA 3EKEA 5AILA 5CBMA 3IIDA 4ZX9A 1NJRA 3V2BA 1LANA 4KYBA 1LAPA 1TY8A 3V45A 3GQOA 4J5RA 1BLLE 2DX6A 4K3NA 4ETKA 3VFQA 3SIHA 2XD7A 3GPOA 3Q71A 3PEIA 5FSUA 3ETIA 3EJGA 4ETJA 3EWQA 1SPVA 3JZTA 4J4ZA 4ESSA 3EWRA 4IQYA 3H8GA 3EJFA
chains in the Genus database with same CATH superfamily
4ZX8A 3EWOA 3H8FA 2FAVA 5FSYA 2AFCA 4JVVA 4ZY2A 4ABKA 4ZY1A 5FSVA 5CMSA 2JZEA 3KR5A 1BPNA 2ACFA 3SIGA 3Q6ZA 4ZY0A 3JRUA 3KQXA 4GVVA 4JCAA 4UMLA 2W2GA 3H8EA 3SIJA 5E3BA 2VRIA 4J5QA 4J5SA 4KSIA 3IIFA 3GPQA 1BPMA 5D8NA 2J9AA 4ABLA 3EW5A 3KQZA 1ZR5A 3GPGA 4K0CA 2JZFA 5FSXA 1ZR3A 4TU0A 2L8RA 4R7MA 5HOLA 2EWBA 1YD9A 2WCTA 2BFRA 4X2TA 5HIHA 1HJZA 2LGRA 1TXZA 2FG1A 5DUSA 4JGKA 3T8WA 3EWPA 5CB3A 4GVWA 4ZYQA 4ZI6A 4JLLA 5CB5A 1LCPA 2JZDA 3GQEA 4R6TA 4R76A 3SIIA 2FXKA 2X47A 3KR4A 2KQVA 3IJ3A 4D86A 1GYTA 2EEEA 4GUAA 1VHUA 2BFQA 3KZWA 1LAMA 5FSZA 3EKEA 5AILA 5CBMA 3IIDA 4ZX9A 1NJRA 3V2BA 1LANA 4KYBA 1LAPA 1TY8A 3V45A 3GQOA 4J5RA 1BLLE 2DX6A 4K3NA 4ETKA 3VFQA 3SIHA 2XD7A 3GPOA 3Q71A 3PEIA 5FSUA 3ETIA 3EJGA 2RNKA 4ETJA 3EWQA 1SPVA 3JZTA 4J4ZA 4ESSA 3EWRA 4IQYA 3H8GA 3EJFA
chains in the Genus database with same CATH topology
4ZX8A 3EWOA 3H8FA 2FAVA 5FSYA 2AFCA 4JVVA 4ZY2A 4ABKA 4ZY1A 5FSVA 5CMSA 3KR5A 1BPNA 2ACFA 3SIGA 3Q6ZA 4ZY0A 3JRUA 3KQXA 4GVVA 4JCAA 4UMLA 3H8EA 3SIJA 5E3BA 2VRIA 4J5QA 4J5SA 4KSIA 3IIFA 3GPQA 1BPMA 5D8NA 2J9AA 4ABLA 3EW5A 3KQZA 1ZR5A 3GPGA 4K0CA 5FSXA 1ZR3A 4TU0A 2L8RA 4R7MA 5HOLA 2EWBA 1YD9A 2BFRA 4X2TA 5HIHA 1HJZA 2LGRA 1TXZA 2FG1A 5DUSA 4JGKA 3T8WA 3EWPA 5CB3A 4GVWA 4ZYQA 4ZI6A 4JLLA 5CB5A 1LCPA 3GQEA 4R6TA 4R76A 3SIIA 2FXKA 2X47A 3KR4A 3IJ3A 4D86A 1GYTA 2EEEA 4GUAA 1VHUA 2BFQA 3KZWA 1LAMA 5FSZA 3EKEA 5AILA 5CBMA 3IIDA 4ZX9A 1NJRA 3V2BA 1LANA 4KYBA 1LAPA 1TY8A 3V45A 3GQOA 4J5RA 1BLLE 2DX6A 4K3NA 4ETKA 3VFQA 3SIHA 2XD7A 3GPOA 3Q71A 3PEIA 5FSUA 3ETIA 3EJGA 4ETJA 3EWQA 1SPVA 3JZTA 4J4ZA 4ESSA 3EWRA 4IQYA 3H8GA 3EJFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZX8 A;  3EWO A;  3H8F A;  2FAV A;  5FSY A;  2AFC A;  4JVV A;  4ZY2 A;  4ABK A;  4ZY1 A;  5FSV A;  5CMS A;  3KR5 A;  1BPN A;  2ACF A;  3SIG A;  3Q6Z A;  4ZY0 A;  3JRU A;  3KQX A;  4GVV A;  4JCA A;  4UML A;  3H8E A;  3SIJ A;  5E3B A;  2VRI A;  4J5Q A;  4J5S A;  4KSI A;  3IIF A;  3GPQ A;  1BPM A;  5D8N A;  2J9A A;  4ABL A;  3EW5 A;  3KQZ A;  1ZR5 A;  3GPG A;  4K0C A;  5FSX A;  1ZR3 A;  4TU0 A;  2L8R A;  4R7M A;  5HOL A;  2EWB A;  1YD9 A;  2BFR A;  4X2T A;  5HIH A;  1HJZ A;  2LGR A;  1TXZ A;  2FG1 A;  5DUS A;  4JGK A;  3T8W A;  3EWP A;  5CB3 A;  4GVW A;  4ZYQ A;  4ZI6 A;  4JLL A;  5CB5 A;  1LCP A;  3GQE A;  4R6T A;  4R76 A;  3SII A;  2FXK A;  2X47 A;  3KR4 A;  3IJ3 A;  4D86 A;  1GYT A;  2EEE A;  4GUA A;  1VHU A;  2BFQ A;  3KZW A;  1LAM A;  5FSZ A;  3EKE A;  5AIL A;  5CBM A;  3IID A;  4ZX9 A;  1NJR A;  3V2B A;  1LAN A;  4KYB A;  1LAP A;  1TY8 A;  3V45 A;  3GQO A;  4J5R A;  1BLL E;  2DX6 A;  4K3N A;  4ETK A;  3VFQ A;  3SIH A;  2XD7 A;  3GPO A;  3Q71 A;  3PEI A;  5FSU A;  3ETI A;  3EJG A;  4ETJ A;  3EWQ A;  1SPV A;  3JZT A;  4J4Z A;  4ESS A;  3EWR A;  4IQY A;  3H8G A;  3EJF A; 
#chains in the Genus database with same CATH topology
 4ZX8 A;  3EWO A;  3H8F A;  2FAV A;  5FSY A;  2AFC A;  4JVV A;  4ZY2 A;  4ABK A;  4ZY1 A;  5FSV A;  5CMS A;  2JZE A;  3KR5 A;  1BPN A;  2ACF A;  3SIG A;  3Q6Z A;  4ZY0 A;  3JRU A;  3KQX A;  4GVV A;  4JCA A;  4UML A;  2W2G A;  3H8E A;  3SIJ A;  5E3B A;  2VRI A;  4J5Q A;  4J5S A;  4KSI A;  3IIF A;  3GPQ A;  1BPM A;  5D8N A;  2J9A A;  4ABL A;  3EW5 A;  3KQZ A;  1ZR5 A;  3GPG A;  4K0C A;  2JZF A;  5FSX A;  1ZR3 A;  4TU0 A;  2L8R A;  4R7M A;  5HOL A;  2EWB A;  1YD9 A;  2WCT A;  2BFR A;  4X2T A;  5HIH A;  1HJZ A;  2LGR A;  1TXZ A;  2FG1 A;  5DUS A;  4JGK A;  3T8W A;  3EWP A;  5CB3 A;  4GVW A;  4ZYQ A;  4ZI6 A;  4JLL A;  5CB5 A;  1LCP A;  2JZD A;  3GQE A;  4R6T A;  4R76 A;  3SII A;  2FXK A;  2X47 A;  3KR4 A;  2KQV A;  3IJ3 A;  4D86 A;  1GYT A;  2EEE A;  4GUA A;  1VHU A;  2BFQ A;  3KZW A;  1LAM A;  5FSZ A;  3EKE A;  5AIL A;  5CBM A;  3IID A;  4ZX9 A;  1NJR A;  3V2B A;  1LAN A;  4KYB A;  1LAP A;  1TY8 A;  3V45 A;  3GQO A;  4J5R A;  1BLL E;  2DX6 A;  4K3N A;  4ETK A;  3VFQ A;  3SIH A;  2XD7 A;  3GPO A;  3Q71 A;  3PEI A;  5FSU A;  3ETI A;  3EJG A;  2RNK A;  4ETJ A;  3EWQ A;  1SPV A;  3JZT A;  4J4Z A;  4ESS A;  3EWR A;  4IQY A;  3H8G A;  3EJF A; 
#chains in the Genus database with same CATH homology
 4ZX8 A;  3EWO A;  3H8F A;  2FAV A;  5FSY A;  2AFC A;  4JVV A;  4ZY2 A;  4ABK A;  4ZY1 A;  5FSV A;  5CMS A;  3KR5 A;  1BPN A;  2ACF A;  3SIG A;  3Q6Z A;  4ZY0 A;  3JRU A;  3KQX A;  4GVV A;  4JCA A;  4UML A;  3H8E A;  3SIJ A;  5E3B A;  2VRI A;  4J5Q A;  4J5S A;  4KSI A;  3IIF A;  3GPQ A;  1BPM A;  5D8N A;  2J9A A;  4ABL A;  3EW5 A;  3KQZ A;  1ZR5 A;  3GPG A;  4K0C A;  5FSX A;  1ZR3 A;  4TU0 A;  2L8R A;  4R7M A;  5HOL A;  2EWB A;  1YD9 A;  2BFR A;  4X2T A;  5HIH A;  1HJZ A;  2LGR A;  1TXZ A;  2FG1 A;  5DUS A;  4JGK A;  3T8W A;  3EWP A;  5CB3 A;  4GVW A;  4ZYQ A;  4ZI6 A;  4JLL A;  5CB5 A;  1LCP A;  3GQE A;  4R6T A;  4R76 A;  3SII A;  2FXK A;  2X47 A;  3KR4 A;  3IJ3 A;  4D86 A;  1GYT A;  2EEE A;  4GUA A;  1VHU A;  2BFQ A;  3KZW A;  1LAM A;  5FSZ A;  3EKE A;  5AIL A;  5CBM A;  3IID A;  4ZX9 A;  1NJR A;  3V2B A;  1LAN A;  4KYB A;  1LAP A;  1TY8 A;  3V45 A;  3GQO A;  4J5R A;  1BLL E;  2DX6 A;  4K3N A;  4ETK A;  3VFQ A;  3SIH A;  2XD7 A;  3GPO A;  3Q71 A;  3PEI A;  5FSU A;  3ETI A;  3EJG A;  4ETJ A;  3EWQ A;  1SPV A;  3JZT A;  4J4Z A;  4ESS A;  3EWR A;  4IQY A;  3H8G A;  3EJF A; 
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similar chains in the Genus database (?% sequence similarity)
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