3SIJA

The x-ray crystal structure of poly(adp-ribose) glycohydrolase e115a mutant from thermomonospora curvata
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
Knots found
sequence length
274
structure length
265
Chain Sequence
RHSRRAIAAETVEILERGRYTAPSGRVVPIADHVAQAVRGTRLYRPEKLAVLLEGTRIEVTEETTLAAARRLTGAAGDQVACLNFASAEHPGGGFLSGAHAQEAGLARSSGLYASLRAVPQFYAFHHRQRDPLYSDHLIYSPGVPVFRDDAGRLLEEPYRVAFLTSPAPNRRAIGDLRTVEEIGRVLRGRAAKVLAAARHHGHRRLVLGAWGCGVFGNDPAQVAETFAGLLLDGGPFAGRFAHVVFAVWDTAPGAPRHAAFARRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermomonospora curvata
molecule keywords poly(ADP-ribose) glycohydrolase
total genus 89
structure length 265
sequence length 274
other databases KnotProt 2.0: K +31
ec nomenclature ec 3.2.1.143: Poly(ADP-ribose) glycohydrolase.
pdb deposition date 2011-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10021 DUF2263 Uncharacterized protein conserved in bacteria (DUF2263)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3sijA00
5D8NA 5FSUA 4ZY0A 5E3BA 4ZI6A 2L8RA 3SIJA 3EWQA 4JLLA 4K0CA 1YD9A 1GYTA 4J5SA 3VFQA 1TY8A 3EWPA 1TXZA 3KZWA 4ZX9A 3GQOA 3H8EA 4KSIA 3GPQA 4JVVA 4ABLA 3KR4A 2EWBA 3EW5A 1SPVA 3PEIA 4ZYQA 3JZTA 3SIHA 5CBMA 4GUAA 5AILA 4GVVA 1BPMA 3GQEA 1BPNA 5CMSA 2X47A 1ZR5A 5FSZA 2BFRA 3IJ3A 4ZY1A 1HJZA 5CB3A 3KQXA 4UMLA 1BLLE 3ETIA 3EJFA 1ZR3A 4JCAA 2J9AA 4J4ZA 3KQZA 5FSVA 3SIIA 2FXKA 3V2BA 1VHUA 2DX6A 3T8WA 2FAVA 4KYBA 5DUSA 3JRUA 2EEEA 1LAMA 3Q6ZA 4K3NA 3EKEA 4ESSA 2FG1A 2XD7A 2BFQA 3Q71A 4D86A 1NJRA 3H8FA 4J5RA 4R76A 4R7MA 3EWOA 4IQYA 5CB5A 3GPGA 3SIGA 4ZY2A 3H8GA 5FSYA 4ABKA 3IIFA 4ZX8A 4R6TA 4X2TA 2ACFA 3KR5A 5FSXA 4TU0A 3EWRA 4GVWA 4J5QA 5HOLA 4ETJA 3V45A 4ETKA 3GPOA 3IIDA 4JGKA 2VRIA 1LCPA 1LAPA 1LANA 3EJGA 2LGRA 5HIHA 2AFCA
chains in the Genus database with same CATH superfamily
5D8NA 5FSUA 4ZY0A 5E3BA 2JZFA 4ZI6A 2L8RA 3SIJA 3EWQA 4JLLA 4K0CA 1YD9A 1GYTA 4J5SA 3VFQA 1TY8A 3EWPA 1TXZA 3KZWA 4ZX9A 3GQOA 3H8EA 4KSIA 3GPQA 4JVVA 2JZDA 3KR4A 4ABLA 2EWBA 3EW5A 1SPVA 3PEIA 4ZYQA 3JZTA 3SIHA 2KQVA 5CBMA 4GUAA 5AILA 2W2GA 4GVVA 1BPMA 3GQEA 1BPNA 5CMSA 2X47A 1ZR5A 5FSZA 2BFRA 3IJ3A 4ZY1A 1HJZA 5CB3A 3KQXA 4UMLA 1BLLE 3ETIA 3EJFA 1ZR3A 4JCAA 2J9AA 4J4ZA 3KQZA 5FSVA 3SIIA 2FXKA 3V2BA 1VHUA 2DX6A 3T8WA 2FAVA 4KYBA 5DUSA 3JRUA 2EEEA 1LAMA 3Q6ZA 4K3NA 3EKEA 4ESSA 2RNKA 2FG1A 2XD7A 2BFQA 3Q71A 4D86A 1NJRA 3H8FA 4J5RA 4R76A 4R7MA 3EWOA 4IQYA 5CB5A 3GPGA 3SIGA 4ZY2A 3H8GA 5FSYA 2WCTA 4ABKA 3IIFA 4ZX8A 4R6TA 4X2TA 2ACFA 2JZEA 3KR5A 5FSXA 4TU0A 3EWRA 4GVWA 4J5QA 5HOLA 4ETJA 3V45A 4ETKA 3GPOA 3IIDA 4JGKA 2VRIA 1LCPA 1LAPA 1LANA 3EJGA 2LGRA 5HIHA 2AFCA
chains in the Genus database with same CATH topology
5D8NA 5FSUA 4ZY0A 5E3BA 4ZI6A 2L8RA 3SIJA 3EWQA 4JLLA 4K0CA 1YD9A 1GYTA 4J5SA 3VFQA 1TY8A 3EWPA 1TXZA 3KZWA 4ZX9A 3GQOA 3H8EA 4KSIA 3GPQA 4JVVA 4ABLA 3KR4A 2EWBA 3EW5A 1SPVA 3PEIA 4ZYQA 3JZTA 3SIHA 5CBMA 4GUAA 5AILA 4GVVA 1BPMA 3GQEA 1BPNA 5CMSA 2X47A 1ZR5A 5FSZA 2BFRA 3IJ3A 4ZY1A 1HJZA 5CB3A 3KQXA 4UMLA 1BLLE 3ETIA 3EJFA 1ZR3A 4JCAA 2J9AA 4J4ZA 3KQZA 5FSVA 3SIIA 2FXKA 3V2BA 1VHUA 2DX6A 3T8WA 2FAVA 4KYBA 5DUSA 3JRUA 2EEEA 1LAMA 3Q6ZA 4K3NA 3EKEA 4ESSA 2FG1A 2XD7A 2BFQA 3Q71A 4D86A 1NJRA 3H8FA 4J5RA 4R76A 4R7MA 3EWOA 4IQYA 5CB5A 3GPGA 3SIGA 4ZY2A 3H8GA 5FSYA 4ABKA 3IIFA 4ZX8A 4R6TA 4X2TA 2ACFA 3KR5A 5FSXA 4TU0A 3EWRA 4GVWA 4J5QA 5HOLA 4ETJA 3V45A 4ETKA 3GPOA 3IIDA 4JGKA 2VRIA 1LCPA 1LAPA 1LANA 3EJGA 2LGRA 5HIHA 2AFCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D8N A;  5FSU A;  4ZY0 A;  5E3B A;  4ZI6 A;  2L8R A;  3SIJ A;  3EWQ A;  4JLL A;  4K0C A;  1YD9 A;  1GYT A;  4J5S A;  3VFQ A;  1TY8 A;  3EWP A;  1TXZ A;  3KZW A;  4ZX9 A;  3GQO A;  3H8E A;  4KSI A;  3GPQ A;  4JVV A;  4ABL A;  3KR4 A;  2EWB A;  3EW5 A;  1SPV A;  3PEI A;  4ZYQ A;  3JZT A;  3SIH A;  5CBM A;  4GUA A;  5AIL A;  4GVV A;  1BPM A;  3GQE A;  1BPN A;  5CMS A;  2X47 A;  1ZR5 A;  5FSZ A;  2BFR A;  3IJ3 A;  4ZY1 A;  1HJZ A;  5CB3 A;  3KQX A;  4UML A;  1BLL E;  3ETI A;  3EJF A;  1ZR3 A;  4JCA A;  2J9A A;  4J4Z A;  3KQZ A;  5FSV A;  3SII A;  2FXK A;  3V2B A;  1VHU A;  2DX6 A;  3T8W A;  2FAV A;  4KYB A;  5DUS A;  3JRU A;  2EEE A;  1LAM A;  3Q6Z A;  4K3N A;  3EKE A;  4ESS A;  2FG1 A;  2XD7 A;  2BFQ A;  3Q71 A;  4D86 A;  1NJR A;  3H8F A;  4J5R A;  4R76 A;  4R7M A;  3EWO A;  4IQY A;  5CB5 A;  3GPG A;  3SIG A;  4ZY2 A;  3H8G A;  5FSY A;  4ABK A;  3IIF A;  4ZX8 A;  4R6T A;  4X2T A;  2ACF A;  3KR5 A;  5FSX A;  4TU0 A;  3EWR A;  4GVW A;  4J5Q A;  5HOL A;  4ETJ A;  3V45 A;  4ETK A;  3GPO A;  3IID A;  4JGK A;  2VRI A;  1LCP A;  1LAP A;  1LAN A;  3EJG A;  2LGR A;  5HIH A;  2AFC A; 
#chains in the Genus database with same CATH topology
 5D8N A;  5FSU A;  4ZY0 A;  5E3B A;  2JZF A;  4ZI6 A;  2L8R A;  3SIJ A;  3EWQ A;  4JLL A;  4K0C A;  1YD9 A;  1GYT A;  4J5S A;  3VFQ A;  1TY8 A;  3EWP A;  1TXZ A;  3KZW A;  4ZX9 A;  3GQO A;  3H8E A;  4KSI A;  3GPQ A;  4JVV A;  2JZD A;  3KR4 A;  4ABL A;  2EWB A;  3EW5 A;  1SPV A;  3PEI A;  4ZYQ A;  3JZT A;  3SIH A;  2KQV A;  5CBM A;  4GUA A;  5AIL A;  2W2G A;  4GVV A;  1BPM A;  3GQE A;  1BPN A;  5CMS A;  2X47 A;  1ZR5 A;  5FSZ A;  2BFR A;  3IJ3 A;  4ZY1 A;  1HJZ A;  5CB3 A;  3KQX A;  4UML A;  1BLL E;  3ETI A;  3EJF A;  1ZR3 A;  4JCA A;  2J9A A;  4J4Z A;  3KQZ A;  5FSV A;  3SII A;  2FXK A;  3V2B A;  1VHU A;  2DX6 A;  3T8W A;  2FAV A;  4KYB A;  5DUS A;  3JRU A;  2EEE A;  1LAM A;  3Q6Z A;  4K3N A;  3EKE A;  4ESS A;  2RNK A;  2FG1 A;  2XD7 A;  2BFQ A;  3Q71 A;  4D86 A;  1NJR A;  3H8F A;  4J5R A;  4R76 A;  4R7M A;  3EWO A;  4IQY A;  5CB5 A;  3GPG A;  3SIG A;  4ZY2 A;  3H8G A;  5FSY A;  2WCT A;  4ABK A;  3IIF A;  4ZX8 A;  4R6T A;  4X2T A;  2ACF A;  2JZE A;  3KR5 A;  5FSX A;  4TU0 A;  3EWR A;  4GVW A;  4J5Q A;  5HOL A;  4ETJ A;  3V45 A;  4ETK A;  3GPO A;  3IID A;  4JGK A;  2VRI A;  1LCP A;  1LAP A;  1LAN A;  3EJG A;  2LGR A;  5HIH A;  2AFC A; 
#chains in the Genus database with same CATH homology
 5D8N A;  5FSU A;  4ZY0 A;  5E3B A;  4ZI6 A;  2L8R A;  3SIJ A;  3EWQ A;  4JLL A;  4K0C A;  1YD9 A;  1GYT A;  4J5S A;  3VFQ A;  1TY8 A;  3EWP A;  1TXZ A;  3KZW A;  4ZX9 A;  3GQO A;  3H8E A;  4KSI A;  3GPQ A;  4JVV A;  4ABL A;  3KR4 A;  2EWB A;  3EW5 A;  1SPV A;  3PEI A;  4ZYQ A;  3JZT A;  3SIH A;  5CBM A;  4GUA A;  5AIL A;  4GVV A;  1BPM A;  3GQE A;  1BPN A;  5CMS A;  2X47 A;  1ZR5 A;  5FSZ A;  2BFR A;  3IJ3 A;  4ZY1 A;  1HJZ A;  5CB3 A;  3KQX A;  4UML A;  1BLL E;  3ETI A;  3EJF A;  1ZR3 A;  4JCA A;  2J9A A;  4J4Z A;  3KQZ A;  5FSV A;  3SII A;  2FXK A;  3V2B A;  1VHU A;  2DX6 A;  3T8W A;  2FAV A;  4KYB A;  5DUS A;  3JRU A;  2EEE A;  1LAM A;  3Q6Z A;  4K3N A;  3EKE A;  4ESS A;  2FG1 A;  2XD7 A;  2BFQ A;  3Q71 A;  4D86 A;  1NJR A;  3H8F A;  4J5R A;  4R76 A;  4R7M A;  3EWO A;  4IQY A;  5CB5 A;  3GPG A;  3SIG A;  4ZY2 A;  3H8G A;  5FSY A;  4ABK A;  3IIF A;  4ZX8 A;  4R6T A;  4X2T A;  2ACF A;  3KR5 A;  5FSX A;  4TU0 A;  3EWR A;  4GVW A;  4J5Q A;  5HOL A;  4ETJ A;  3V45 A;  4ETK A;  3GPO A;  3IID A;  4JGK A;  2VRI A;  1LCP A;  1LAP A;  1LAN A;  3EJG A;  2LGR A;  5HIH A;  2AFC A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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