3V45A

Crystal structure of de novo designed serine hydrolase osh55, northeast structural genomics consortium target or130
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
166
structure length
166
Chain Sequence
ARIREVQGDITEFQGDAIVNAANNYLKLGAGVAGAILRKGGPSIQEECDRIGKIRVGEAAVTGAGNLPVRYVIHAAVLGDEPASLETVRKATKSALEKAVELGLKTVAFTALGAWVGGLPAEAVLRVMLEEIKKAPDTLEVTGVHGTEKSAEAARRALLEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design of activated serine-containing catalytic triads with atomic-level accuracy.
pubmed doi rcsb
molecule tags De novo protein
molecule keywords Serine hydrolase OSH55
total genus 56
structure length 166
sequence length 166
ec nomenclature
pdb deposition date 2011-12-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3v45A00
4TU0A 2EEEA 5CB3A 5E3BA 5FSVA 3IIDA 2XD7A 4J5RA 4ZY0A 4D86A 4ABLA 3EJFA 3KZWA 4J4ZA 5DUSA 2DX6A 5AILA 3SIGA 5CBMA 1HJZA 3GPGA 2ACFA 3T8WA 4ABKA 1BLLE 3V45A 4J5SA 1BPMA 1TXZA 3EWOA 3H8GA 2FAVA 4GVWA 5HIHA 2L8RA 2X47A 2BFRA 3KQXA 4ZI6A 3ETIA 3Q6ZA 4R7MA 4JLLA 2FXKA 1YD9A 4ZY2A 5FSXA 3GPQA 3GQOA 3EJGA 2VRIA 3SIHA 3VFQA 1LCPA 4KYBA 5CB5A 4ZYQA 3PEIA 3Q71A 1GYTA 1ZR3A 3JRUA 3EWRA 4GVVA 4X2TA 4R76A 4JCAA 1SPVA 3SIIA 3JZTA 1TY8A 2EWBA 4ETKA 1LAMA 3EWPA 5FSZA 1LANA 1BPNA 4GUAA 4IQYA 4K3NA 3SIJA 3GQEA 3H8EA 5FSYA 2LGRA 4ESSA 1ZR5A 4JVVA 4ZY1A 4ETJA 3EWQA 3KR5A 2AFCA 2BFQA 5HOLA 4R6TA 1VHUA 2J9AA 4K0CA 3GPOA 5D8NA 3V2BA 3KR4A 4ZX9A 3EKEA 5CMSA 4J5QA 3EW5A 5FSUA 1NJRA 4KSIA 2FG1A 4JGKA 3KQZA 1LAPA 4UMLA 4ZX8A 3H8FA 3IJ3A 3IIFA
chains in the Genus database with same CATH superfamily
2WCTA 4TU0A 2EEEA 5CB3A 5E3BA 5FSVA 3IIDA 2XD7A 4J5RA 4ZY0A 4D86A 4ABLA 3EJFA 2KQVA 3KZWA 4J4ZA 5DUSA 2DX6A 5AILA 3SIGA 5CBMA 1HJZA 3GPGA 2ACFA 3T8WA 4ABKA 1BLLE 3V45A 4J5SA 1BPMA 1TXZA 3EWOA 3H8GA 2FAVA 4GVWA 5HIHA 2L8RA 2X47A 2BFRA 3KQXA 4ZI6A 2JZFA 3ETIA 3Q6ZA 4R7MA 4JLLA 2FXKA 1YD9A 4ZY2A 5FSXA 3GPQA 3GQOA 3EJGA 2VRIA 3SIHA 3VFQA 1LCPA 4KYBA 5CB5A 4ZYQA 3PEIA 3Q71A 1GYTA 1ZR3A 3JRUA 3EWRA 4GVVA 4X2TA 4R76A 4JCAA 1SPVA 3SIIA 3JZTA 1TY8A 2EWBA 4ETKA 1LAMA 3EWPA 5FSZA 1LANA 1BPNA 4GUAA 4IQYA 4K3NA 2W2GA 3SIJA 3GQEA 3H8EA 5FSYA 2LGRA 4ESSA 2JZDA 1ZR5A 4JVVA 4ZY1A 4ETJA 3EWQA 3KR5A 2AFCA 2BFQA 5HOLA 4R6TA 1VHUA 2J9AA 4K0CA 3GPOA 5D8NA 3V2BA 3KR4A 4ZX9A 2JZEA 2RNKA 3EKEA 5CMSA 4J5QA 3EW5A 5FSUA 1NJRA 4KSIA 2FG1A 4JGKA 3KQZA 1LAPA 4UMLA 4ZX8A 3H8FA 3IJ3A 3IIFA
chains in the Genus database with same CATH topology
4TU0A 2EEEA 5CB3A 5E3BA 5FSVA 3IIDA 2XD7A 4J5RA 4ZY0A 4D86A 4ABLA 3EJFA 3KZWA 4J4ZA 5DUSA 2DX6A 5AILA 3SIGA 5CBMA 1HJZA 3GPGA 2ACFA 3T8WA 4ABKA 1BLLE 3V45A 4J5SA 1BPMA 1TXZA 3EWOA 3H8GA 2FAVA 4GVWA 5HIHA 2L8RA 2X47A 2BFRA 3KQXA 4ZI6A 3ETIA 3Q6ZA 4R7MA 4JLLA 2FXKA 1YD9A 4ZY2A 5FSXA 3GPQA 3GQOA 3EJGA 2VRIA 3SIHA 3VFQA 1LCPA 4KYBA 5CB5A 4ZYQA 3PEIA 3Q71A 1GYTA 1ZR3A 3JRUA 3EWRA 4GVVA 4X2TA 4R76A 4JCAA 1SPVA 3SIIA 3JZTA 1TY8A 2EWBA 4ETKA 1LAMA 3EWPA 5FSZA 1LANA 1BPNA 4GUAA 4IQYA 4K3NA 3SIJA 3GQEA 3H8EA 5FSYA 2LGRA 4ESSA 1ZR5A 4JVVA 4ZY1A 4ETJA 3EWQA 3KR5A 2AFCA 2BFQA 5HOLA 4R6TA 1VHUA 2J9AA 4K0CA 3GPOA 5D8NA 3V2BA 3KR4A 4ZX9A 3EKEA 5CMSA 4J5QA 3EW5A 5FSUA 1NJRA 4KSIA 2FG1A 4JGKA 3KQZA 1LAPA 4UMLA 4ZX8A 3H8FA 3IJ3A 3IIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TU0 A;  2EEE A;  5CB3 A;  5E3B A;  5FSV A;  3IID A;  2XD7 A;  4J5R A;  4ZY0 A;  4D86 A;  4ABL A;  3EJF A;  3KZW A;  4J4Z A;  5DUS A;  2DX6 A;  5AIL A;  3SIG A;  5CBM A;  1HJZ A;  3GPG A;  2ACF A;  3T8W A;  4ABK A;  1BLL E;  3V45 A;  4J5S A;  1BPM A;  1TXZ A;  3EWO A;  3H8G A;  2FAV A;  4GVW A;  5HIH A;  2L8R A;  2X47 A;  2BFR A;  3KQX A;  4ZI6 A;  3ETI A;  3Q6Z A;  4R7M A;  4JLL A;  2FXK A;  1YD9 A;  4ZY2 A;  5FSX A;  3GPQ A;  3GQO A;  3EJG A;  2VRI A;  3SIH A;  3VFQ A;  1LCP A;  4KYB A;  5CB5 A;  4ZYQ A;  3PEI A;  3Q71 A;  1GYT A;  1ZR3 A;  3JRU A;  3EWR A;  4GVV A;  4X2T A;  4R76 A;  4JCA A;  1SPV A;  3SII A;  3JZT A;  1TY8 A;  2EWB A;  4ETK A;  1LAM A;  3EWP A;  5FSZ A;  1LAN A;  1BPN A;  4GUA A;  4IQY A;  4K3N A;  3SIJ A;  3GQE A;  3H8E A;  5FSY A;  2LGR A;  4ESS A;  1ZR5 A;  4JVV A;  4ZY1 A;  4ETJ A;  3EWQ A;  3KR5 A;  2AFC A;  2BFQ A;  5HOL A;  4R6T A;  1VHU A;  2J9A A;  4K0C A;  3GPO A;  5D8N A;  3V2B A;  3KR4 A;  4ZX9 A;  3EKE A;  5CMS A;  4J5Q A;  3EW5 A;  5FSU A;  1NJR A;  4KSI A;  2FG1 A;  4JGK A;  3KQZ A;  1LAP A;  4UML A;  4ZX8 A;  3H8F A;  3IJ3 A;  3IIF A; 
#chains in the Genus database with same CATH topology
 2WCT A;  4TU0 A;  2EEE A;  5CB3 A;  5E3B A;  5FSV A;  3IID A;  2XD7 A;  4J5R A;  4ZY0 A;  4D86 A;  4ABL A;  3EJF A;  2KQV A;  3KZW A;  4J4Z A;  5DUS A;  2DX6 A;  5AIL A;  3SIG A;  5CBM A;  1HJZ A;  3GPG A;  2ACF A;  3T8W A;  4ABK A;  1BLL E;  3V45 A;  4J5S A;  1BPM A;  1TXZ A;  3EWO A;  3H8G A;  2FAV A;  4GVW A;  5HIH A;  2L8R A;  2X47 A;  2BFR A;  3KQX A;  4ZI6 A;  2JZF A;  3ETI A;  3Q6Z A;  4R7M A;  4JLL A;  2FXK A;  1YD9 A;  4ZY2 A;  5FSX A;  3GPQ A;  3GQO A;  3EJG A;  2VRI A;  3SIH A;  3VFQ A;  1LCP A;  4KYB A;  5CB5 A;  4ZYQ A;  3PEI A;  3Q71 A;  1GYT A;  1ZR3 A;  3JRU A;  3EWR A;  4GVV A;  4X2T A;  4R76 A;  4JCA A;  1SPV A;  3SII A;  3JZT A;  1TY8 A;  2EWB A;  4ETK A;  1LAM A;  3EWP A;  5FSZ A;  1LAN A;  1BPN A;  4GUA A;  4IQY A;  4K3N A;  2W2G A;  3SIJ A;  3GQE A;  3H8E A;  5FSY A;  2LGR A;  4ESS A;  2JZD A;  1ZR5 A;  4JVV A;  4ZY1 A;  4ETJ A;  3EWQ A;  3KR5 A;  2AFC A;  2BFQ A;  5HOL A;  4R6T A;  1VHU A;  2J9A A;  4K0C A;  3GPO A;  5D8N A;  3V2B A;  3KR4 A;  4ZX9 A;  2JZE A;  2RNK A;  3EKE A;  5CMS A;  4J5Q A;  3EW5 A;  5FSU A;  1NJR A;  4KSI A;  2FG1 A;  4JGK A;  3KQZ A;  1LAP A;  4UML A;  4ZX8 A;  3H8F A;  3IJ3 A;  3IIF A; 
#chains in the Genus database with same CATH homology
 4TU0 A;  2EEE A;  5CB3 A;  5E3B A;  5FSV A;  3IID A;  2XD7 A;  4J5R A;  4ZY0 A;  4D86 A;  4ABL A;  3EJF A;  3KZW A;  4J4Z A;  5DUS A;  2DX6 A;  5AIL A;  3SIG A;  5CBM A;  1HJZ A;  3GPG A;  2ACF A;  3T8W A;  4ABK A;  1BLL E;  3V45 A;  4J5S A;  1BPM A;  1TXZ A;  3EWO A;  3H8G A;  2FAV A;  4GVW A;  5HIH A;  2L8R A;  2X47 A;  2BFR A;  3KQX A;  4ZI6 A;  3ETI A;  3Q6Z A;  4R7M A;  4JLL A;  2FXK A;  1YD9 A;  4ZY2 A;  5FSX A;  3GPQ A;  3GQO A;  3EJG A;  2VRI A;  3SIH A;  3VFQ A;  1LCP A;  4KYB A;  5CB5 A;  4ZYQ A;  3PEI A;  3Q71 A;  1GYT A;  1ZR3 A;  3JRU A;  3EWR A;  4GVV A;  4X2T A;  4R76 A;  4JCA A;  1SPV A;  3SII A;  3JZT A;  1TY8 A;  2EWB A;  4ETK A;  1LAM A;  3EWP A;  5FSZ A;  1LAN A;  1BPN A;  4GUA A;  4IQY A;  4K3N A;  3SIJ A;  3GQE A;  3H8E A;  5FSY A;  2LGR A;  4ESS A;  1ZR5 A;  4JVV A;  4ZY1 A;  4ETJ A;  3EWQ A;  3KR5 A;  2AFC A;  2BFQ A;  5HOL A;  4R6T A;  1VHU A;  2J9A A;  4K0C A;  3GPO A;  5D8N A;  3V2B A;  3KR4 A;  4ZX9 A;  3EKE A;  5CMS A;  4J5Q A;  3EW5 A;  5FSU A;  1NJR A;  4KSI A;  2FG1 A;  4JGK A;  3KQZ A;  1LAP A;  4UML A;  4ZX8 A;  3H8F A;  3IJ3 A;  3IIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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