3EJGA

Crystal structure of hcov-229e x-domain
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
165
structure length
165
Chain Sequence
EKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSLRIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEVCKVKDFVSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human coronavirus 229e
molecule keywords Non-structural protein 3
total genus 55
structure length 165
sequence length 165
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2008-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3ejgA00
3IIFA 3H8FA 4ZY0A 4ZY2A 2X47A 4GUAA 5D8NA 3GPOA 4GVVA 4GVWA 5FSUA 4KSIA 3EJFA 3EWOA 3EW5A 5FSXA 4UMLA 4J5RA 4JVVA 4ZI6A 2DX6A 3ETIA 4ABKA 1BPNA 4JGKA 4ESSA 2FXKA 4R7MA 4ZYQA 3SIJA 4X2TA 5CB5A 1LANA 2FAVA 3KR5A 3H8EA 1TY8A 4JCAA 2VRIA 5FSYA 3GQOA 3JZTA 4ETJA 3GPQA 3EWRA 2L8RA 3EWQA 4J5QA 3Q6ZA 1ZR3A 2XD7A 5CB3A 1LCPA 2EWBA 4J4ZA 2BFRA 3IJ3A 3VFQA 3V45A 5AILA 4D86A 3GQEA 4JLLA 3KQZA 2BFQA 1LAMA 1VHUA 3EJGA 4TU0A 2EEEA 3KR4A 5CBMA 3Q71A 3PEIA 2LGRA 4J5SA 1BLLE 5DUSA 4K3NA 5E3BA 3SIGA 3KQXA 1LAPA 3EKEA 5FSVA 4ZX9A 4ZX8A 3SIHA 1SPVA 5CMSA 3H8GA 4R76A 4ETKA 1YD9A 2FG1A 5HIHA 4R6TA 2AFCA 1BPMA 3JRUA 4IQYA 3GPGA 5FSZA 1TXZA 3IIDA 3SIIA 4KYBA 4ABLA 3EWPA 5HOLA 4K0CA 1GYTA 1NJRA 1HJZA 3KZWA 3T8WA 2J9AA 4ZY1A 2ACFA 1ZR5A 3V2BA
chains in the Genus database with same CATH superfamily
3IIFA 3H8FA 4ZY0A 4ZY2A 2X47A 4GUAA 5D8NA 3GPOA 4GVVA 4GVWA 5FSUA 4KSIA 3EJFA 3EWOA 2JZFA 3EW5A 5FSXA 4UMLA 4J5RA 4JVVA 4ZI6A 2DX6A 3ETIA 4ABKA 1BPNA 4JGKA 4ESSA 2FXKA 4R7MA 4ZYQA 3SIJA 4X2TA 5CB5A 1LANA 2FAVA 3KR5A 3H8EA 1TY8A 4JCAA 2VRIA 5FSYA 3GQOA 3JZTA 4ETJA 3GPQA 3EWRA 2L8RA 3EWQA 4J5QA 3Q6ZA 1ZR3A 2XD7A 5CB3A 1LCPA 2JZDA 2EWBA 4J4ZA 2BFRA 3IJ3A 3VFQA 3V45A 5AILA 4D86A 3GQEA 4JLLA 3KQZA 2BFQA 1LAMA 1VHUA 3EJGA 4TU0A 2EEEA 3KR4A 5CBMA 3Q71A 3PEIA 2LGRA 4J5SA 1BLLE 5DUSA 4K3NA 5E3BA 3SIGA 3KQXA 1LAPA 3EKEA 5FSVA 4ZX9A 4ZX8A 3SIHA 1SPVA 5CMSA 3H8GA 4R76A 4ETKA 1YD9A 2FG1A 5HIHA 4R6TA 2AFCA 1BPMA 2WCTA 3JRUA 4IQYA 2JZEA 2W2GA 3GPGA 5FSZA 1TXZA 3IIDA 2RNKA 3SIIA 2KQVA 4KYBA 4ABLA 3EWPA 5HOLA 4K0CA 1GYTA 1NJRA 1HJZA 3KZWA 3T8WA 2J9AA 4ZY1A 2ACFA 1ZR5A 3V2BA
chains in the Genus database with same CATH topology
3IIFA 3H8FA 4ZY0A 4ZY2A 2X47A 4GUAA 5D8NA 3GPOA 4GVVA 4GVWA 5FSUA 4KSIA 3EJFA 3EWOA 3EW5A 5FSXA 4UMLA 4J5RA 4JVVA 4ZI6A 2DX6A 3ETIA 4ABKA 1BPNA 4JGKA 4ESSA 2FXKA 4R7MA 4ZYQA 3SIJA 4X2TA 5CB5A 1LANA 2FAVA 3KR5A 3H8EA 1TY8A 4JCAA 2VRIA 5FSYA 3GQOA 3JZTA 4ETJA 3GPQA 3EWRA 2L8RA 3EWQA 4J5QA 3Q6ZA 1ZR3A 2XD7A 5CB3A 1LCPA 2EWBA 4J4ZA 2BFRA 3IJ3A 3VFQA 3V45A 5AILA 4D86A 3GQEA 4JLLA 3KQZA 2BFQA 1LAMA 1VHUA 3EJGA 4TU0A 2EEEA 3KR4A 5CBMA 3Q71A 3PEIA 2LGRA 4J5SA 1BLLE 5DUSA 4K3NA 5E3BA 3SIGA 3KQXA 1LAPA 3EKEA 5FSVA 4ZX9A 4ZX8A 3SIHA 1SPVA 5CMSA 3H8GA 4R76A 4ETKA 1YD9A 2FG1A 5HIHA 4R6TA 2AFCA 1BPMA 3JRUA 4IQYA 3GPGA 5FSZA 1TXZA 3IIDA 3SIIA 4KYBA 4ABLA 3EWPA 5HOLA 4K0CA 1GYTA 1NJRA 1HJZA 3KZWA 3T8WA 2J9AA 4ZY1A 2ACFA 1ZR5A 3V2BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IIF A;  3H8F A;  4ZY0 A;  4ZY2 A;  2X47 A;  4GUA A;  5D8N A;  3GPO A;  4GVV A;  4GVW A;  5FSU A;  4KSI A;  3EJF A;  3EWO A;  3EW5 A;  5FSX A;  4UML A;  4J5R A;  4JVV A;  4ZI6 A;  2DX6 A;  3ETI A;  4ABK A;  1BPN A;  4JGK A;  4ESS A;  2FXK A;  4R7M A;  4ZYQ A;  3SIJ A;  4X2T A;  5CB5 A;  1LAN A;  2FAV A;  3KR5 A;  3H8E A;  1TY8 A;  4JCA A;  2VRI A;  5FSY A;  3GQO A;  3JZT A;  4ETJ A;  3GPQ A;  3EWR A;  2L8R A;  3EWQ A;  4J5Q A;  3Q6Z A;  1ZR3 A;  2XD7 A;  5CB3 A;  1LCP A;  2EWB A;  4J4Z A;  2BFR A;  3IJ3 A;  3VFQ A;  3V45 A;  5AIL A;  4D86 A;  3GQE A;  4JLL A;  3KQZ A;  2BFQ A;  1LAM A;  1VHU A;  3EJG A;  4TU0 A;  2EEE A;  3KR4 A;  5CBM A;  3Q71 A;  3PEI A;  2LGR A;  4J5S A;  1BLL E;  5DUS A;  4K3N A;  5E3B A;  3SIG A;  3KQX A;  1LAP A;  3EKE A;  5FSV A;  4ZX9 A;  4ZX8 A;  3SIH A;  1SPV A;  5CMS A;  3H8G A;  4R76 A;  4ETK A;  1YD9 A;  2FG1 A;  5HIH A;  4R6T A;  2AFC A;  1BPM A;  3JRU A;  4IQY A;  3GPG A;  5FSZ A;  1TXZ A;  3IID A;  3SII A;  4KYB A;  4ABL A;  3EWP A;  5HOL A;  4K0C A;  1GYT A;  1NJR A;  1HJZ A;  3KZW A;  3T8W A;  2J9A A;  4ZY1 A;  2ACF A;  1ZR5 A;  3V2B A; 
#chains in the Genus database with same CATH topology
 3IIF A;  3H8F A;  4ZY0 A;  4ZY2 A;  2X47 A;  4GUA A;  5D8N A;  3GPO A;  4GVV A;  4GVW A;  5FSU A;  4KSI A;  3EJF A;  3EWO A;  2JZF A;  3EW5 A;  5FSX A;  4UML A;  4J5R A;  4JVV A;  4ZI6 A;  2DX6 A;  3ETI A;  4ABK A;  1BPN A;  4JGK A;  4ESS A;  2FXK A;  4R7M A;  4ZYQ A;  3SIJ A;  4X2T A;  5CB5 A;  1LAN A;  2FAV A;  3KR5 A;  3H8E A;  1TY8 A;  4JCA A;  2VRI A;  5FSY A;  3GQO A;  3JZT A;  4ETJ A;  3GPQ A;  3EWR A;  2L8R A;  3EWQ A;  4J5Q A;  3Q6Z A;  1ZR3 A;  2XD7 A;  5CB3 A;  1LCP A;  2JZD A;  2EWB A;  4J4Z A;  2BFR A;  3IJ3 A;  3VFQ A;  3V45 A;  5AIL A;  4D86 A;  3GQE A;  4JLL A;  3KQZ A;  2BFQ A;  1LAM A;  1VHU A;  3EJG A;  4TU0 A;  2EEE A;  3KR4 A;  5CBM A;  3Q71 A;  3PEI A;  2LGR A;  4J5S A;  1BLL E;  5DUS A;  4K3N A;  5E3B A;  3SIG A;  3KQX A;  1LAP A;  3EKE A;  5FSV A;  4ZX9 A;  4ZX8 A;  3SIH A;  1SPV A;  5CMS A;  3H8G A;  4R76 A;  4ETK A;  1YD9 A;  2FG1 A;  5HIH A;  4R6T A;  2AFC A;  1BPM A;  2WCT A;  3JRU A;  4IQY A;  2JZE A;  2W2G A;  3GPG A;  5FSZ A;  1TXZ A;  3IID A;  2RNK A;  3SII A;  2KQV A;  4KYB A;  4ABL A;  3EWP A;  5HOL A;  4K0C A;  1GYT A;  1NJR A;  1HJZ A;  3KZW A;  3T8W A;  2J9A A;  4ZY1 A;  2ACF A;  1ZR5 A;  3V2B A; 
#chains in the Genus database with same CATH homology
 3IIF A;  3H8F A;  4ZY0 A;  4ZY2 A;  2X47 A;  4GUA A;  5D8N A;  3GPO A;  4GVV A;  4GVW A;  5FSU A;  4KSI A;  3EJF A;  3EWO A;  3EW5 A;  5FSX A;  4UML A;  4J5R A;  4JVV A;  4ZI6 A;  2DX6 A;  3ETI A;  4ABK A;  1BPN A;  4JGK A;  4ESS A;  2FXK A;  4R7M A;  4ZYQ A;  3SIJ A;  4X2T A;  5CB5 A;  1LAN A;  2FAV A;  3KR5 A;  3H8E A;  1TY8 A;  4JCA A;  2VRI A;  5FSY A;  3GQO A;  3JZT A;  4ETJ A;  3GPQ A;  3EWR A;  2L8R A;  3EWQ A;  4J5Q A;  3Q6Z A;  1ZR3 A;  2XD7 A;  5CB3 A;  1LCP A;  2EWB A;  4J4Z A;  2BFR A;  3IJ3 A;  3VFQ A;  3V45 A;  5AIL A;  4D86 A;  3GQE A;  4JLL A;  3KQZ A;  2BFQ A;  1LAM A;  1VHU A;  3EJG A;  4TU0 A;  2EEE A;  3KR4 A;  5CBM A;  3Q71 A;  3PEI A;  2LGR A;  4J5S A;  1BLL E;  5DUS A;  4K3N A;  5E3B A;  3SIG A;  3KQX A;  1LAP A;  3EKE A;  5FSV A;  4ZX9 A;  4ZX8 A;  3SIH A;  1SPV A;  5CMS A;  3H8G A;  4R76 A;  4ETK A;  1YD9 A;  2FG1 A;  5HIH A;  4R6T A;  2AFC A;  1BPM A;  3JRU A;  4IQY A;  3GPG A;  5FSZ A;  1TXZ A;  3IID A;  3SII A;  4KYB A;  4ABL A;  3EWP A;  5HOL A;  4K0C A;  1GYT A;  1NJR A;  1HJZ A;  3KZW A;  3T8W A;  2J9A A;  4ZY1 A;  2ACF A;  1ZR5 A;  3V2B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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