3EWRA

Complex of substrate adp-ribose with hcov-229e nsp3 adrp domain
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
167
structure length
167
Chain Sequence
KEKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSLRIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human coronavirus 229e
molecule keywords Non-structural protein 3
total genus 52
structure length 167
sequence length 167
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2008-10-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3ewrA00
3GPQA 5FSUA 1BPMA 2X47A 4J5RA 4ZX8A 3Q6ZA 4GVVA 4K3NA 2VRIA 2DX6A 4J5SA 4D86A 1TXZA 4ZI6A 4IQYA 5DUSA 2EEEA 5FSZA 5FSYA 4ZY1A 5CMSA 1TY8A 3GQEA 1SPVA 3SIHA 2BFRA 3EJGA 1YD9A 3KQXA 1HJZA 3EWQA 4ABKA 2FXKA 4ABLA 4R76A 1LAPA 4JCAA 3PEIA 2ACFA 3KR5A 1ZR3A 3EW5A 3V45A 4ETJA 5HOLA 2L8RA 3IJ3A 3EWPA 4JLLA 5FSXA 1VHUA 3T8WA 1NJRA 2J9AA 4ESSA 3SIIA 5CB5A 3EJFA 3JZTA 3KZWA 3GPGA 4X2TA 3VFQA 3JRUA 3EKEA 3KR4A 3ETIA 3IIFA 2FAVA 3H8EA 4JVVA 4KSIA 4JGKA 1LCPA 1GYTA 4GVWA 3EWOA 2BFQA 3H8GA 2AFCA 5E3BA 5FSVA 4KYBA 3GPOA 3H8FA 1LANA 4ZX9A 5AILA 3SIJA 4TU0A 1LAMA 2EWBA 3EWRA 4ZY0A 4ZYQA 3GQOA 1BPNA 4ETKA 3V2BA 4K0CA 1BLLE 5D8NA 3Q71A 4UMLA 2FG1A 2LGRA 4ZY2A 4J5QA 2XD7A 3KQZA 3SIGA 4J4ZA 5CBMA 4R6TA 4GUAA 3IIDA 1ZR5A 5CB3A 5HIHA 4R7MA
chains in the Genus database with same CATH superfamily
3GPQA 5FSUA 1BPMA 2X47A 4J5RA 2W2GA 4ZX8A 3Q6ZA 4GVVA 2JZFA 4K3NA 2VRIA 2DX6A 4J5SA 4D86A 1TXZA 4ZI6A 4IQYA 5DUSA 2EEEA 5FSZA 5FSYA 4ZY1A 5CMSA 2JZEA 1TY8A 3GQEA 1SPVA 3SIHA 2BFRA 3EJGA 1YD9A 2RNKA 3KQXA 1HJZA 3EWQA 4ABKA 2FXKA 4ABLA 4R76A 1LAPA 2KQVA 4JCAA 3PEIA 2ACFA 3KR5A 1ZR3A 3EW5A 3V45A 4ETJA 5HOLA 2L8RA 3IJ3A 3EWPA 4JLLA 5FSXA 1VHUA 3T8WA 1NJRA 2J9AA 4ESSA 3SIIA 5CB5A 2WCTA 3EJFA 3JZTA 3KZWA 2JZDA 3GPGA 4X2TA 3JRUA 3VFQA 3EKEA 3KR4A 3ETIA 3IIFA 2FAVA 3H8EA 4JVVA 4KSIA 4JGKA 1LCPA 1GYTA 4GVWA 3EWOA 2BFQA 3H8GA 2AFCA 5E3BA 5FSVA 4KYBA 3GPOA 3H8FA 1LANA 4ZX9A 5AILA 3SIJA 4TU0A 1LAMA 2EWBA 3EWRA 4ZY0A 4ZYQA 3GQOA 1BPNA 4ETKA 3V2BA 4K0CA 1BLLE 5D8NA 3Q71A 4UMLA 2FG1A 2LGRA 4ZY2A 4J5QA 2XD7A 3KQZA 3SIGA 4J4ZA 5CBMA 4R6TA 4GUAA 3IIDA 1ZR5A 5CB3A 5HIHA 4R7MA
chains in the Genus database with same CATH topology
3GPQA 5FSUA 1BPMA 2X47A 4J5RA 4ZX8A 3Q6ZA 4GVVA 4K3NA 2VRIA 2DX6A 4J5SA 4D86A 1TXZA 4ZI6A 4IQYA 5DUSA 2EEEA 5FSZA 5FSYA 4ZY1A 5CMSA 1TY8A 3GQEA 1SPVA 3SIHA 2BFRA 3EJGA 1YD9A 3KQXA 1HJZA 3EWQA 4ABKA 2FXKA 4ABLA 4R76A 1LAPA 4JCAA 3PEIA 2ACFA 3KR5A 1ZR3A 3EW5A 3V45A 4ETJA 5HOLA 2L8RA 3IJ3A 3EWPA 4JLLA 5FSXA 1VHUA 3T8WA 1NJRA 2J9AA 4ESSA 3SIIA 5CB5A 3EJFA 3JZTA 3KZWA 3GPGA 4X2TA 3VFQA 3JRUA 3EKEA 3KR4A 3ETIA 3IIFA 2FAVA 3H8EA 4JVVA 4KSIA 4JGKA 1LCPA 1GYTA 4GVWA 3EWOA 2BFQA 3H8GA 2AFCA 5E3BA 5FSVA 4KYBA 3GPOA 3H8FA 1LANA 4ZX9A 5AILA 3SIJA 4TU0A 1LAMA 2EWBA 3EWRA 4ZY0A 4ZYQA 3GQOA 1BPNA 4ETKA 3V2BA 4K0CA 1BLLE 5D8NA 3Q71A 4UMLA 2FG1A 2LGRA 4ZY2A 4J5QA 2XD7A 3KQZA 3SIGA 4J4ZA 5CBMA 4R6TA 4GUAA 3IIDA 1ZR5A 5CB3A 5HIHA 4R7MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GPQ A;  5FSU A;  1BPM A;  2X47 A;  4J5R A;  4ZX8 A;  3Q6Z A;  4GVV A;  4K3N A;  2VRI A;  2DX6 A;  4J5S A;  4D86 A;  1TXZ A;  4ZI6 A;  4IQY A;  5DUS A;  2EEE A;  5FSZ A;  5FSY A;  4ZY1 A;  5CMS A;  1TY8 A;  3GQE A;  1SPV A;  3SIH A;  2BFR A;  3EJG A;  1YD9 A;  3KQX A;  1HJZ A;  3EWQ A;  4ABK A;  2FXK A;  4ABL A;  4R76 A;  1LAP A;  4JCA A;  3PEI A;  2ACF A;  3KR5 A;  1ZR3 A;  3EW5 A;  3V45 A;  4ETJ A;  5HOL A;  2L8R A;  3IJ3 A;  3EWP A;  4JLL A;  5FSX A;  1VHU A;  3T8W A;  1NJR A;  2J9A A;  4ESS A;  3SII A;  5CB5 A;  3EJF A;  3JZT A;  3KZW A;  3GPG A;  4X2T A;  3VFQ A;  3JRU A;  3EKE A;  3KR4 A;  3ETI A;  3IIF A;  2FAV A;  3H8E A;  4JVV A;  4KSI A;  4JGK A;  1LCP A;  1GYT A;  4GVW A;  3EWO A;  2BFQ A;  3H8G A;  2AFC A;  5E3B A;  5FSV A;  4KYB A;  3GPO A;  3H8F A;  1LAN A;  4ZX9 A;  5AIL A;  3SIJ A;  4TU0 A;  1LAM A;  2EWB A;  3EWR A;  4ZY0 A;  4ZYQ A;  3GQO A;  1BPN A;  4ETK A;  3V2B A;  4K0C A;  1BLL E;  5D8N A;  3Q71 A;  4UML A;  2FG1 A;  2LGR A;  4ZY2 A;  4J5Q A;  2XD7 A;  3KQZ A;  3SIG A;  4J4Z A;  5CBM A;  4R6T A;  4GUA A;  3IID A;  1ZR5 A;  5CB3 A;  5HIH A;  4R7M A; 
#chains in the Genus database with same CATH topology
 3GPQ A;  5FSU A;  1BPM A;  2X47 A;  4J5R A;  2W2G A;  4ZX8 A;  3Q6Z A;  4GVV A;  2JZF A;  4K3N A;  2VRI A;  2DX6 A;  4J5S A;  4D86 A;  1TXZ A;  4ZI6 A;  4IQY A;  5DUS A;  2EEE A;  5FSZ A;  5FSY A;  4ZY1 A;  5CMS A;  2JZE A;  1TY8 A;  3GQE A;  1SPV A;  3SIH A;  2BFR A;  3EJG A;  1YD9 A;  2RNK A;  3KQX A;  1HJZ A;  3EWQ A;  4ABK A;  2FXK A;  4ABL A;  4R76 A;  1LAP A;  2KQV A;  4JCA A;  3PEI A;  2ACF A;  3KR5 A;  1ZR3 A;  3EW5 A;  3V45 A;  4ETJ A;  5HOL A;  2L8R A;  3IJ3 A;  3EWP A;  4JLL A;  5FSX A;  1VHU A;  3T8W A;  1NJR A;  2J9A A;  4ESS A;  3SII A;  5CB5 A;  2WCT A;  3EJF A;  3JZT A;  3KZW A;  2JZD A;  3GPG A;  4X2T A;  3JRU A;  3VFQ A;  3EKE A;  3KR4 A;  3ETI A;  3IIF A;  2FAV A;  3H8E A;  4JVV A;  4KSI A;  4JGK A;  1LCP A;  1GYT A;  4GVW A;  3EWO A;  2BFQ A;  3H8G A;  2AFC A;  5E3B A;  5FSV A;  4KYB A;  3GPO A;  3H8F A;  1LAN A;  4ZX9 A;  5AIL A;  3SIJ A;  4TU0 A;  1LAM A;  2EWB A;  3EWR A;  4ZY0 A;  4ZYQ A;  3GQO A;  1BPN A;  4ETK A;  3V2B A;  4K0C A;  1BLL E;  5D8N A;  3Q71 A;  4UML A;  2FG1 A;  2LGR A;  4ZY2 A;  4J5Q A;  2XD7 A;  3KQZ A;  3SIG A;  4J4Z A;  5CBM A;  4R6T A;  4GUA A;  3IID A;  1ZR5 A;  5CB3 A;  5HIH A;  4R7M A; 
#chains in the Genus database with same CATH homology
 3GPQ A;  5FSU A;  1BPM A;  2X47 A;  4J5R A;  4ZX8 A;  3Q6Z A;  4GVV A;  4K3N A;  2VRI A;  2DX6 A;  4J5S A;  4D86 A;  1TXZ A;  4ZI6 A;  4IQY A;  5DUS A;  2EEE A;  5FSZ A;  5FSY A;  4ZY1 A;  5CMS A;  1TY8 A;  3GQE A;  1SPV A;  3SIH A;  2BFR A;  3EJG A;  1YD9 A;  3KQX A;  1HJZ A;  3EWQ A;  4ABK A;  2FXK A;  4ABL A;  4R76 A;  1LAP A;  4JCA A;  3PEI A;  2ACF A;  3KR5 A;  1ZR3 A;  3EW5 A;  3V45 A;  4ETJ A;  5HOL A;  2L8R A;  3IJ3 A;  3EWP A;  4JLL A;  5FSX A;  1VHU A;  3T8W A;  1NJR A;  2J9A A;  4ESS A;  3SII A;  5CB5 A;  3EJF A;  3JZT A;  3KZW A;  3GPG A;  4X2T A;  3VFQ A;  3JRU A;  3EKE A;  3KR4 A;  3ETI A;  3IIF A;  2FAV A;  3H8E A;  4JVV A;  4KSI A;  4JGK A;  1LCP A;  1GYT A;  4GVW A;  3EWO A;  2BFQ A;  3H8G A;  2AFC A;  5E3B A;  5FSV A;  4KYB A;  3GPO A;  3H8F A;  1LAN A;  4ZX9 A;  5AIL A;  3SIJ A;  4TU0 A;  1LAM A;  2EWB A;  3EWR A;  4ZY0 A;  4ZYQ A;  3GQO A;  1BPN A;  4ETK A;  3V2B A;  4K0C A;  1BLL E;  5D8N A;  3Q71 A;  4UML A;  2FG1 A;  2LGR A;  4ZY2 A;  4J5Q A;  2XD7 A;  3KQZ A;  3SIG A;  4J4Z A;  5CBM A;  4R6T A;  4GUA A;  3IID A;  1ZR5 A;  5CB3 A;  5HIH A;  4R7M A; 
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similar chains in the Genus database (?% sequence similarity)
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