3GPGA

Crystal structure of macro domain of chikungunya virus
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
162
structure length
160
Chain Sequence
HHAPSYVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
pubmed doi rcsb
molecule tags Viral protein
source organism Chikungunya virus
molecule keywords Non-structural protein 3
total genus 54
structure length 160
sequence length 162
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3gpgA00
4J5SA 4ZI6A 5HIHA 4KSIA 3GPQA 3Q71A 5FSUA 4ZX8A 1LCPA 3SIHA 2X47A 3H8GA 3SIJA 4ZY1A 2FAVA 4GVVA 5E3BA 2XD7A 3H8EA 3IJ3A 1NJRA 2L8RA 4K3NA 3EWQA 4R6TA 1HJZA 4ABKA 3GQEA 3H8FA 4ZX9A 3EWRA 4R7MA 5HOLA 1LAMA 5FSZA 5CBMA 2BFRA 2DX6A 3SIGA 3V2BA 1ZR5A 5DUSA 3KQZA 2FXKA 4GVWA 4J5RA 3IIFA 1YD9A 4KYBA 3ETIA 4JLLA 1VHUA 3GQOA 4JVVA 3Q6ZA 3VFQA 3GPOA 3T8WA 1TY8A 4UMLA 3GPGA 4JGKA 2J9AA 1TXZA 4R76A 4ETKA 3EJFA 3KR4A 3PEIA 2FG1A 1ZR3A 1BLLE 4JCAA 2EWBA 3V45A 4ABLA 2LGRA 2VRIA 5AILA 1BPMA 3EJGA 3KZWA 4ESSA 2EEEA 4TU0A 1LAPA 4ZY0A 4K0CA 2AFCA 2ACFA 5FSXA 3EKEA 4ZY2A 2BFQA 3SIIA 3JZTA 5CB5A 4ETJA 3EWOA 4X2TA 3JRUA 1BPNA 5D8NA 4J4ZA 4D86A 4J5QA 3KQXA 1SPVA 3KR5A 1LANA 1GYTA 5FSYA 4ZYQA 3EWPA 3EW5A 5CB3A 3IIDA 4GUAA 4IQYA 5CMSA 5FSVA
chains in the Genus database with same CATH superfamily
4J5SA 4ZI6A 5HIHA 4KSIA 3GPQA 3Q71A 5FSUA 4ZX8A 1LCPA 3SIHA 2X47A 3H8GA 3SIJA 4ZY1A 2FAVA 4GVVA 5E3BA 2XD7A 3H8EA 3IJ3A 1NJRA 2L8RA 4K3NA 3EWQA 4R6TA 2JZFA 1HJZA 4ABKA 3GQEA 3H8FA 4ZX9A 3EWRA 4R7MA 5HOLA 1LAMA 5FSZA 5CBMA 2BFRA 2DX6A 3SIGA 3V2BA 1ZR5A 5DUSA 3KQZA 2FXKA 4GVWA 4J5RA 3IIFA 1YD9A 4KYBA 3ETIA 4JLLA 1VHUA 3GQOA 4JVVA 3Q6ZA 3VFQA 3GPOA 3T8WA 1TY8A 4UMLA 3GPGA 4JGKA 2J9AA 1TXZA 4R76A 4ETKA 3EJFA 3KR4A 3PEIA 2FG1A 1ZR3A 1BLLE 4JCAA 2EWBA 3V45A 4ABLA 2LGRA 2VRIA 5AILA 1BPMA 3EJGA 3KZWA 4ESSA 2EEEA 4TU0A 1LAPA 2WCTA 4ZY0A 4K0CA 2JZEA 2AFCA 2ACFA 5FSXA 3EKEA 4ZY2A 2BFQA 3SIIA 2RNKA 3JZTA 5CB5A 4ETJA 3EWOA 4X2TA 3JRUA 1BPNA 5D8NA 2W2GA 4J4ZA 4D86A 4J5QA 3KQXA 1SPVA 3KR5A 2JZDA 1LANA 1GYTA 5FSYA 2KQVA 4ZYQA 3EWPA 3EW5A 5CB3A 3IIDA 4GUAA 4IQYA 5CMSA 5FSVA
chains in the Genus database with same CATH topology
4J5SA 4ZI6A 5HIHA 4KSIA 3GPQA 3Q71A 5FSUA 4ZX8A 1LCPA 3SIHA 2X47A 3H8GA 3SIJA 4ZY1A 2FAVA 4GVVA 5E3BA 2XD7A 3H8EA 3IJ3A 1NJRA 2L8RA 4K3NA 3EWQA 4R6TA 1HJZA 4ABKA 3GQEA 3H8FA 4ZX9A 3EWRA 4R7MA 5HOLA 1LAMA 5FSZA 5CBMA 2BFRA 2DX6A 3SIGA 3V2BA 1ZR5A 5DUSA 3KQZA 2FXKA 4GVWA 4J5RA 3IIFA 1YD9A 4KYBA 3ETIA 4JLLA 1VHUA 3GQOA 4JVVA 3Q6ZA 3VFQA 3GPOA 3T8WA 1TY8A 4UMLA 3GPGA 4JGKA 2J9AA 1TXZA 4R76A 4ETKA 3EJFA 3KR4A 3PEIA 2FG1A 1ZR3A 1BLLE 4JCAA 2EWBA 3V45A 4ABLA 2LGRA 2VRIA 5AILA 1BPMA 3EJGA 3KZWA 4ESSA 2EEEA 4TU0A 1LAPA 4ZY0A 4K0CA 2AFCA 2ACFA 5FSXA 3EKEA 4ZY2A 2BFQA 3SIIA 3JZTA 5CB5A 4ETJA 3EWOA 4X2TA 3JRUA 1BPNA 5D8NA 4J4ZA 4D86A 4J5QA 3KQXA 1SPVA 3KR5A 1LANA 1GYTA 5FSYA 4ZYQA 3EWPA 3EW5A 5CB3A 3IIDA 4GUAA 4IQYA 5CMSA 5FSVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J5S A;  4ZI6 A;  5HIH A;  4KSI A;  3GPQ A;  3Q71 A;  5FSU A;  4ZX8 A;  1LCP A;  3SIH A;  2X47 A;  3H8G A;  3SIJ A;  4ZY1 A;  2FAV A;  4GVV A;  5E3B A;  2XD7 A;  3H8E A;  3IJ3 A;  1NJR A;  2L8R A;  4K3N A;  3EWQ A;  4R6T A;  1HJZ A;  4ABK A;  3GQE A;  3H8F A;  4ZX9 A;  3EWR A;  4R7M A;  5HOL A;  1LAM A;  5FSZ A;  5CBM A;  2BFR A;  2DX6 A;  3SIG A;  3V2B A;  1ZR5 A;  5DUS A;  3KQZ A;  2FXK A;  4GVW A;  4J5R A;  3IIF A;  1YD9 A;  4KYB A;  3ETI A;  4JLL A;  1VHU A;  3GQO A;  4JVV A;  3Q6Z A;  3VFQ A;  3GPO A;  3T8W A;  1TY8 A;  4UML A;  3GPG A;  4JGK A;  2J9A A;  1TXZ A;  4R76 A;  4ETK A;  3EJF A;  3KR4 A;  3PEI A;  2FG1 A;  1ZR3 A;  1BLL E;  4JCA A;  2EWB A;  3V45 A;  4ABL A;  2LGR A;  2VRI A;  5AIL A;  1BPM A;  3EJG A;  3KZW A;  4ESS A;  2EEE A;  4TU0 A;  1LAP A;  4ZY0 A;  4K0C A;  2AFC A;  2ACF A;  5FSX A;  3EKE A;  4ZY2 A;  2BFQ A;  3SII A;  3JZT A;  5CB5 A;  4ETJ A;  3EWO A;  4X2T A;  3JRU A;  1BPN A;  5D8N A;  4J4Z A;  4D86 A;  4J5Q A;  3KQX A;  1SPV A;  3KR5 A;  1LAN A;  1GYT A;  5FSY A;  4ZYQ A;  3EWP A;  3EW5 A;  5CB3 A;  3IID A;  4GUA A;  4IQY A;  5CMS A;  5FSV A; 
#chains in the Genus database with same CATH topology
 4J5S A;  4ZI6 A;  5HIH A;  4KSI A;  3GPQ A;  3Q71 A;  5FSU A;  4ZX8 A;  1LCP A;  3SIH A;  2X47 A;  3H8G A;  3SIJ A;  4ZY1 A;  2FAV A;  4GVV A;  5E3B A;  2XD7 A;  3H8E A;  3IJ3 A;  1NJR A;  2L8R A;  4K3N A;  3EWQ A;  4R6T A;  2JZF A;  1HJZ A;  4ABK A;  3GQE A;  3H8F A;  4ZX9 A;  3EWR A;  4R7M A;  5HOL A;  1LAM A;  5FSZ A;  5CBM A;  2BFR A;  2DX6 A;  3SIG A;  3V2B A;  1ZR5 A;  5DUS A;  3KQZ A;  2FXK A;  4GVW A;  4J5R A;  3IIF A;  1YD9 A;  4KYB A;  3ETI A;  4JLL A;  1VHU A;  3GQO A;  4JVV A;  3Q6Z A;  3VFQ A;  3GPO A;  3T8W A;  1TY8 A;  4UML A;  3GPG A;  4JGK A;  2J9A A;  1TXZ A;  4R76 A;  4ETK A;  3EJF A;  3KR4 A;  3PEI A;  2FG1 A;  1ZR3 A;  1BLL E;  4JCA A;  2EWB A;  3V45 A;  4ABL A;  2LGR A;  2VRI A;  5AIL A;  1BPM A;  3EJG A;  3KZW A;  4ESS A;  2EEE A;  4TU0 A;  1LAP A;  2WCT A;  4ZY0 A;  4K0C A;  2JZE A;  2AFC A;  2ACF A;  5FSX A;  3EKE A;  4ZY2 A;  2BFQ A;  3SII A;  2RNK A;  3JZT A;  5CB5 A;  4ETJ A;  3EWO A;  4X2T A;  3JRU A;  1BPN A;  5D8N A;  2W2G A;  4J4Z A;  4D86 A;  4J5Q A;  3KQX A;  1SPV A;  3KR5 A;  2JZD A;  1LAN A;  1GYT A;  5FSY A;  2KQV A;  4ZYQ A;  3EWP A;  3EW5 A;  5CB3 A;  3IID A;  4GUA A;  4IQY A;  5CMS A;  5FSV A; 
#chains in the Genus database with same CATH homology
 4J5S A;  4ZI6 A;  5HIH A;  4KSI A;  3GPQ A;  3Q71 A;  5FSU A;  4ZX8 A;  1LCP A;  3SIH A;  2X47 A;  3H8G A;  3SIJ A;  4ZY1 A;  2FAV A;  4GVV A;  5E3B A;  2XD7 A;  3H8E A;  3IJ3 A;  1NJR A;  2L8R A;  4K3N A;  3EWQ A;  4R6T A;  1HJZ A;  4ABK A;  3GQE A;  3H8F A;  4ZX9 A;  3EWR A;  4R7M A;  5HOL A;  1LAM A;  5FSZ A;  5CBM A;  2BFR A;  2DX6 A;  3SIG A;  3V2B A;  1ZR5 A;  5DUS A;  3KQZ A;  2FXK A;  4GVW A;  4J5R A;  3IIF A;  1YD9 A;  4KYB A;  3ETI A;  4JLL A;  1VHU A;  3GQO A;  4JVV A;  3Q6Z A;  3VFQ A;  3GPO A;  3T8W A;  1TY8 A;  4UML A;  3GPG A;  4JGK A;  2J9A A;  1TXZ A;  4R76 A;  4ETK A;  3EJF A;  3KR4 A;  3PEI A;  2FG1 A;  1ZR3 A;  1BLL E;  4JCA A;  2EWB A;  3V45 A;  4ABL A;  2LGR A;  2VRI A;  5AIL A;  1BPM A;  3EJG A;  3KZW A;  4ESS A;  2EEE A;  4TU0 A;  1LAP A;  4ZY0 A;  4K0C A;  2AFC A;  2ACF A;  5FSX A;  3EKE A;  4ZY2 A;  2BFQ A;  3SII A;  3JZT A;  5CB5 A;  4ETJ A;  3EWO A;  4X2T A;  3JRU A;  1BPN A;  5D8N A;  4J4Z A;  4D86 A;  4J5Q A;  3KQX A;  1SPV A;  3KR5 A;  1LAN A;  1GYT A;  5FSY A;  4ZYQ A;  3EWP A;  3EW5 A;  5CB3 A;  3IID A;  4GUA A;  4IQY A;  5CMS A;  5FSV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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