3GPQA

Crystal structure of macro domain of chikungunya virus in complex with rna
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
160
structure length
160
Chain Sequence
APSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
pubmed doi rcsb
molecule tags Viral protein/rna
source organism Chikungunya virus
molecule keywords Non-structural protein 3
total genus 50
structure length 160
sequence length 160
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3gpqA00
4R7MA 4ABLA 1SPVA 4JVVA 3KZWA 1TXZA 3H8GA 4D86A 2FAVA 3SIHA 4K0CA 4GVVA 4JCAA 2J9AA 2FG1A 1GYTA 1YD9A 4K3NA 4JGKA 3PEIA 3SIIA 4JLLA 5HOLA 1LCPA 3Q6ZA 2FXKA 3EKEA 5CMSA 5FSVA 5AILA 3V45A 4ZYQA 3GQEA 5D8NA 3GPGA 4J5RA 2BFRA 5CB3A 1LAPA 2EWBA 1NJRA 3EW5A 1BLLE 4ZX9A 3H8EA 5CBMA 4ESSA 3VFQA 5FSUA 4R76A 3V2BA 2XD7A 3IIFA 1BPNA 4J4ZA 4UMLA 4GVWA 5E3BA 4ZY0A 1HJZA 1BPMA 2EEEA 4ABKA 2DX6A 2VRIA 3IIDA 2BFQA 5HIHA 2LGRA 3GQOA 3EWQA 3EWRA 5DUSA 3JRUA 1LANA 4ZY2A 4J5QA 4TU0A 3EWPA 3GPQA 3EWOA 1TY8A 3KR4A 2X47A 3Q71A 5FSZA 5FSXA 3KQZA 4ZI6A 1LAMA 1ZR5A 4GUAA 4ETJA 4KSIA 4ETKA 1VHUA 3H8FA 4ZY1A 4IQYA 3ETIA 4X2TA 2AFCA 3KR5A 4R6TA 5FSYA 3GPOA 3IJ3A 4J5SA 4ZX8A 3EJFA 3EJGA 3SIJA 4KYBA 3T8WA 1ZR3A 2L8RA 3JZTA 3KQXA 3SIGA 5CB5A 2ACFA
chains in the Genus database with same CATH superfamily
4R7MA 2KQVA 4ABLA 2W2GA 1SPVA 4JVVA 3KZWA 1TXZA 3H8GA 4D86A 2FAVA 2JZEA 3SIHA 4K0CA 4GVVA 4JCAA 2J9AA 2FG1A 1GYTA 1YD9A 4K3NA 4JGKA 3PEIA 3SIIA 2JZFA 4JLLA 5HOLA 1LCPA 3Q6ZA 2FXKA 3EKEA 5CMSA 5FSVA 5AILA 3V45A 4ZYQA 2RNKA 3GQEA 5D8NA 3GPGA 4J5RA 2BFRA 5CB3A 1LAPA 2EWBA 1NJRA 3EW5A 1BLLE 4ZX9A 3H8EA 5CBMA 4ESSA 3VFQA 5FSUA 4R76A 3V2BA 2XD7A 3IIFA 1BPNA 4J4ZA 4UMLA 4GVWA 5E3BA 4ZY0A 1HJZA 1BPMA 2EEEA 4ABKA 2DX6A 2VRIA 3IIDA 2BFQA 5HIHA 2LGRA 3GQOA 3EWQA 3EWRA 2WCTA 5DUSA 3JRUA 1LANA 4ZY2A 2JZDA 4J5QA 4TU0A 3EWPA 3GPQA 3EWOA 1TY8A 3KR4A 2X47A 3Q71A 5FSZA 5FSXA 3KQZA 4ZI6A 1LAMA 1ZR5A 4GUAA 4ETJA 4KSIA 4ETKA 1VHUA 3H8FA 4ZY1A 4IQYA 3ETIA 4X2TA 2AFCA 3KR5A 4R6TA 5FSYA 3GPOA 3IJ3A 4J5SA 4ZX8A 3EJFA 3EJGA 3SIJA 4KYBA 3T8WA 1ZR3A 2L8RA 3JZTA 3KQXA 3SIGA 5CB5A 2ACFA
chains in the Genus database with same CATH topology
4R7MA 4ABLA 1SPVA 4JVVA 3KZWA 1TXZA 3H8GA 4D86A 2FAVA 3SIHA 4K0CA 4GVVA 4JCAA 2J9AA 2FG1A 1GYTA 1YD9A 4K3NA 4JGKA 3PEIA 3SIIA 4JLLA 5HOLA 1LCPA 3Q6ZA 2FXKA 3EKEA 5CMSA 5FSVA 5AILA 3V45A 4ZYQA 3GQEA 5D8NA 3GPGA 4J5RA 2BFRA 5CB3A 1LAPA 2EWBA 1NJRA 3EW5A 1BLLE 4ZX9A 3H8EA 5CBMA 4ESSA 3VFQA 5FSUA 4R76A 3V2BA 2XD7A 3IIFA 1BPNA 4J4ZA 4UMLA 4GVWA 5E3BA 4ZY0A 1HJZA 1BPMA 2EEEA 4ABKA 2DX6A 2VRIA 3IIDA 2BFQA 5HIHA 2LGRA 3GQOA 3EWQA 3EWRA 5DUSA 3JRUA 1LANA 4ZY2A 4J5QA 4TU0A 3EWPA 3GPQA 3EWOA 1TY8A 3KR4A 2X47A 3Q71A 5FSZA 5FSXA 3KQZA 4ZI6A 1LAMA 1ZR5A 4GUAA 4ETJA 4KSIA 4ETKA 1VHUA 3H8FA 4ZY1A 4IQYA 3ETIA 4X2TA 2AFCA 3KR5A 4R6TA 5FSYA 3GPOA 3IJ3A 4J5SA 4ZX8A 3EJFA 3EJGA 3SIJA 4KYBA 3T8WA 1ZR3A 2L8RA 3JZTA 3KQXA 3SIGA 5CB5A 2ACFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R7M A;  4ABL A;  1SPV A;  4JVV A;  3KZW A;  1TXZ A;  3H8G A;  4D86 A;  2FAV A;  3SIH A;  4K0C A;  4GVV A;  4JCA A;  2J9A A;  2FG1 A;  1GYT A;  1YD9 A;  4K3N A;  4JGK A;  3PEI A;  3SII A;  4JLL A;  5HOL A;  1LCP A;  3Q6Z A;  2FXK A;  3EKE A;  5CMS A;  5FSV A;  5AIL A;  3V45 A;  4ZYQ A;  3GQE A;  5D8N A;  3GPG A;  4J5R A;  2BFR A;  5CB3 A;  1LAP A;  2EWB A;  1NJR A;  3EW5 A;  1BLL E;  4ZX9 A;  3H8E A;  5CBM A;  4ESS A;  3VFQ A;  5FSU A;  4R76 A;  3V2B A;  2XD7 A;  3IIF A;  1BPN A;  4J4Z A;  4UML A;  4GVW A;  5E3B A;  4ZY0 A;  1HJZ A;  1BPM A;  2EEE A;  4ABK A;  2DX6 A;  2VRI A;  3IID A;  2BFQ A;  5HIH A;  2LGR A;  3GQO A;  3EWQ A;  3EWR A;  5DUS A;  3JRU A;  1LAN A;  4ZY2 A;  4J5Q A;  4TU0 A;  3EWP A;  3GPQ A;  3EWO A;  1TY8 A;  3KR4 A;  2X47 A;  3Q71 A;  5FSZ A;  5FSX A;  3KQZ A;  4ZI6 A;  1LAM A;  1ZR5 A;  4GUA A;  4ETJ A;  4KSI A;  4ETK A;  1VHU A;  3H8F A;  4ZY1 A;  4IQY A;  3ETI A;  4X2T A;  2AFC A;  3KR5 A;  4R6T A;  5FSY A;  3GPO A;  3IJ3 A;  4J5S A;  4ZX8 A;  3EJF A;  3EJG A;  3SIJ A;  4KYB A;  3T8W A;  1ZR3 A;  2L8R A;  3JZT A;  3KQX A;  3SIG A;  5CB5 A;  2ACF A; 
#chains in the Genus database with same CATH topology
 4R7M A;  2KQV A;  4ABL A;  2W2G A;  1SPV A;  4JVV A;  3KZW A;  1TXZ A;  3H8G A;  4D86 A;  2FAV A;  2JZE A;  3SIH A;  4K0C A;  4GVV A;  4JCA A;  2J9A A;  2FG1 A;  1GYT A;  1YD9 A;  4K3N A;  4JGK A;  3PEI A;  3SII A;  2JZF A;  4JLL A;  5HOL A;  1LCP A;  3Q6Z A;  2FXK A;  3EKE A;  5CMS A;  5FSV A;  5AIL A;  3V45 A;  4ZYQ A;  2RNK A;  3GQE A;  5D8N A;  3GPG A;  4J5R A;  2BFR A;  5CB3 A;  1LAP A;  2EWB A;  1NJR A;  3EW5 A;  1BLL E;  4ZX9 A;  3H8E A;  5CBM A;  4ESS A;  3VFQ A;  5FSU A;  4R76 A;  3V2B A;  2XD7 A;  3IIF A;  1BPN A;  4J4Z A;  4UML A;  4GVW A;  5E3B A;  4ZY0 A;  1HJZ A;  1BPM A;  2EEE A;  4ABK A;  2DX6 A;  2VRI A;  3IID A;  2BFQ A;  5HIH A;  2LGR A;  3GQO A;  3EWQ A;  3EWR A;  2WCT A;  5DUS A;  3JRU A;  1LAN A;  4ZY2 A;  2JZD A;  4J5Q A;  4TU0 A;  3EWP A;  3GPQ A;  3EWO A;  1TY8 A;  3KR4 A;  2X47 A;  3Q71 A;  5FSZ A;  5FSX A;  3KQZ A;  4ZI6 A;  1LAM A;  1ZR5 A;  4GUA A;  4ETJ A;  4KSI A;  4ETK A;  1VHU A;  3H8F A;  4ZY1 A;  4IQY A;  3ETI A;  4X2T A;  2AFC A;  3KR5 A;  4R6T A;  5FSY A;  3GPO A;  3IJ3 A;  4J5S A;  4ZX8 A;  3EJF A;  3EJG A;  3SIJ A;  4KYB A;  3T8W A;  1ZR3 A;  2L8R A;  3JZT A;  3KQX A;  3SIG A;  5CB5 A;  2ACF A; 
#chains in the Genus database with same CATH homology
 4R7M A;  4ABL A;  1SPV A;  4JVV A;  3KZW A;  1TXZ A;  3H8G A;  4D86 A;  2FAV A;  3SIH A;  4K0C A;  4GVV A;  4JCA A;  2J9A A;  2FG1 A;  1GYT A;  1YD9 A;  4K3N A;  4JGK A;  3PEI A;  3SII A;  4JLL A;  5HOL A;  1LCP A;  3Q6Z A;  2FXK A;  3EKE A;  5CMS A;  5FSV A;  5AIL A;  3V45 A;  4ZYQ A;  3GQE A;  5D8N A;  3GPG A;  4J5R A;  2BFR A;  5CB3 A;  1LAP A;  2EWB A;  1NJR A;  3EW5 A;  1BLL E;  4ZX9 A;  3H8E A;  5CBM A;  4ESS A;  3VFQ A;  5FSU A;  4R76 A;  3V2B A;  2XD7 A;  3IIF A;  1BPN A;  4J4Z A;  4UML A;  4GVW A;  5E3B A;  4ZY0 A;  1HJZ A;  1BPM A;  2EEE A;  4ABK A;  2DX6 A;  2VRI A;  3IID A;  2BFQ A;  5HIH A;  2LGR A;  3GQO A;  3EWQ A;  3EWR A;  5DUS A;  3JRU A;  1LAN A;  4ZY2 A;  4J5Q A;  4TU0 A;  3EWP A;  3GPQ A;  3EWO A;  1TY8 A;  3KR4 A;  2X47 A;  3Q71 A;  5FSZ A;  5FSX A;  3KQZ A;  4ZI6 A;  1LAM A;  1ZR5 A;  4GUA A;  4ETJ A;  4KSI A;  4ETK A;  1VHU A;  3H8F A;  4ZY1 A;  4IQY A;  3ETI A;  4X2T A;  2AFC A;  3KR5 A;  4R6T A;  5FSY A;  3GPO A;  3IJ3 A;  4J5S A;  4ZX8 A;  3EJF A;  3EJG A;  3SIJ A;  4KYB A;  3T8W A;  1ZR3 A;  2L8R A;  3JZT A;  3KQX A;  3SIG A;  5CB5 A;  2ACF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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