4D86A

Human parp14 (artd8, bal2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
374
Chain Sequence
KCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Poly [ADP-ribose] polymerase 14
total genus 137
structure length 374
sequence length 401
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4d86A02
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4d86A01
4ZYQA 4ABKA 1LANA 3JZTA 4ETKA 4ESSA 4JGKA 3EWRA 4ABLA 4J4ZA 3SIIA 2LGRA 4JLLA 3Q6ZA 4KSIA 1ZR3A 5E3BA 1GYTA 5FSYA 2XD7A 3EKEA 3EWQA 4GVVA 2BFRA 2L8RA 2EWBA 2VRIA 3V2BA 4J5QA 2FAVA 4JCAA 1LCPA 3KZWA 4ETJA 1TXZA 3EJFA 4GUAA 4ZY2A 3ETIA 3GQEA 5FSVA 2ACFA 4KYBA 2DX6A 3VFQA 3KQXA 4ZI6A 4JVVA 3Q71A 1BLLE 5FSXA 3EWOA 2AFCA 4J5RA 3IJ3A 2J9AA 3KR5A 3EW5A 1HJZA 3H8EA 2BFQA 5FSUA 4R6TA 3H8GA 1LAMA 1VHUA 5AILA 1TY8A 2FXKA 5CB5A 4K3NA 3SIHA 4ZY0A 3EWPA 3PEIA 3GPGA 1BPMA 4GVWA 4X2TA 4UMLA 4ZX9A 3JRUA 4R76A 1BPNA 4J5SA 4ZX8A 5CB3A 3EJGA 3IIFA 4IQYA 3KQZA 3IIDA 3GPQA 5CMSA 1NJRA 3GPOA 5HIHA 5HOLA 4K0CA 5FSZA 3KR4A 5DUSA 1LAPA 2X47A 4R7MA 2FG1A 1SPVA 3SIGA 3H8FA 2EEEA 3GQOA 1YD9A 1ZR5A 5D8NA 4D86A 3V45A 4ZY1A 4TU0A 3T8WA 3SIJA 5CBMA
chains in the Genus database with same CATH superfamily
4ZYQA 4ABKA 1LANA 3JZTA 4ETKA 4ESSA 4JGKA 3EWRA 4ABLA 2WCTA 4J4ZA 3SIIA 2LGRA 4JLLA 3Q6ZA 4KSIA 1ZR3A 5E3BA 1GYTA 5FSYA 2XD7A 3EKEA 3EWQA 4GVVA 2BFRA 2L8RA 2EWBA 2VRIA 3V2BA 4J5QA 2FAVA 4JCAA 1LCPA 2JZFA 3KZWA 4ETJA 1TXZA 2JZDA 3EJFA 4GUAA 4ZY2A 3ETIA 3GQEA 5FSVA 2ACFA 4KYBA 2DX6A 2JZEA 3VFQA 3KQXA 4ZI6A 4JVVA 3Q71A 1BLLE 5FSXA 3EWOA 2AFCA 4J5RA 3IJ3A 2J9AA 3KR5A 3EW5A 1HJZA 3H8EA 2BFQA 5FSUA 4R6TA 3H8GA 1LAMA 1VHUA 5AILA 1TY8A 2FXKA 5CB5A 4K3NA 3SIHA 4ZY0A 3EWPA 3PEIA 3GPGA 2KQVA 1BPMA 4GVWA 4X2TA 4UMLA 4ZX9A 3JRUA 4R76A 1BPNA 4J5SA 4ZX8A 5CB3A 3EJGA 3IIFA 4IQYA 3KQZA 2RNKA 3IIDA 3GPQA 5CMSA 1NJRA 3GPOA 5HIHA 5HOLA 4K0CA 5FSZA 3KR4A 5DUSA 1LAPA 2X47A 4R7MA 2FG1A 1SPVA 3SIGA 3H8FA 2EEEA 3GQOA 1YD9A 1ZR5A 5D8NA 4D86A 3V45A 4ZY1A 2W2GA 4TU0A 3T8WA 3SIJA 5CBMA
chains in the Genus database with same CATH topology
4ZYQA 4ABKA 1LANA 3JZTA 4ETKA 4ESSA 4JGKA 3EWRA 4ABLA 4J4ZA 3SIIA 2LGRA 4JLLA 3Q6ZA 4KSIA 1ZR3A 5E3BA 1GYTA 5FSYA 2XD7A 3EKEA 3EWQA 4GVVA 2BFRA 2L8RA 2EWBA 2VRIA 3V2BA 4J5QA 2FAVA 4JCAA 1LCPA 3KZWA 4ETJA 1TXZA 3EJFA 4GUAA 4ZY2A 3ETIA 3GQEA 5FSVA 2ACFA 4KYBA 2DX6A 3VFQA 3KQXA 4ZI6A 4JVVA 3Q71A 1BLLE 5FSXA 3EWOA 2AFCA 4J5RA 3IJ3A 2J9AA 3KR5A 3EW5A 1HJZA 3H8EA 2BFQA 5FSUA 4R6TA 3H8GA 1LAMA 1VHUA 5AILA 1TY8A 2FXKA 5CB5A 4K3NA 3SIHA 4ZY0A 3EWPA 3PEIA 3GPGA 1BPMA 4GVWA 4X2TA 4UMLA 4ZX9A 3JRUA 4R76A 1BPNA 4J5SA 4ZX8A 5CB3A 3EJGA 3IIFA 4IQYA 3KQZA 3IIDA 3GPQA 5CMSA 1NJRA 3GPOA 5HIHA 5HOLA 4K0CA 5FSZA 3KR4A 5DUSA 1LAPA 2X47A 4R7MA 2FG1A 1SPVA 3SIGA 3H8FA 2EEEA 3GQOA 1YD9A 1ZR5A 5D8NA 4D86A 3V45A 4ZY1A 4TU0A 3T8WA 3SIJA 5CBMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZYQ A;  4ABK A;  1LAN A;  3JZT A;  4ETK A;  4ESS A;  4JGK A;  3EWR A;  4ABL A;  4J4Z A;  3SII A;  2LGR A;  4JLL A;  3Q6Z A;  4KSI A;  1ZR3 A;  5E3B A;  1GYT A;  5FSY A;  2XD7 A;  3EKE A;  3EWQ A;  4GVV A;  2BFR A;  2L8R A;  2EWB A;  2VRI A;  3V2B A;  4J5Q A;  2FAV A;  4JCA A;  1LCP A;  3KZW A;  4ETJ A;  1TXZ A;  3EJF A;  4GUA A;  4ZY2 A;  3ETI A;  3GQE A;  5FSV A;  2ACF A;  4KYB A;  2DX6 A;  3VFQ A;  3KQX A;  4ZI6 A;  4JVV A;  3Q71 A;  1BLL E;  5FSX A;  3EWO A;  2AFC A;  4J5R A;  3IJ3 A;  2J9A A;  3KR5 A;  3EW5 A;  1HJZ A;  3H8E A;  2BFQ A;  5FSU A;  4R6T A;  3H8G A;  1LAM A;  1VHU A;  5AIL A;  1TY8 A;  2FXK A;  5CB5 A;  4K3N A;  3SIH A;  4ZY0 A;  3EWP A;  3PEI A;  3GPG A;  1BPM A;  4GVW A;  4X2T A;  4UML A;  4ZX9 A;  3JRU A;  4R76 A;  1BPN A;  4J5S A;  4ZX8 A;  5CB3 A;  3EJG A;  3IIF A;  4IQY A;  3KQZ A;  3IID A;  3GPQ A;  5CMS A;  1NJR A;  3GPO A;  5HIH A;  5HOL A;  4K0C A;  5FSZ A;  3KR4 A;  5DUS A;  1LAP A;  2X47 A;  4R7M A;  2FG1 A;  1SPV A;  3SIG A;  3H8F A;  2EEE A;  3GQO A;  1YD9 A;  1ZR5 A;  5D8N A;  4D86 A;  3V45 A;  4ZY1 A;  4TU0 A;  3T8W A;  3SIJ A;  5CBM A; 
#chains in the Genus database with same CATH topology
 4ZYQ A;  4ABK A;  1LAN A;  3JZT A;  4ETK A;  4ESS A;  4JGK A;  3EWR A;  4ABL A;  2WCT A;  4J4Z A;  3SII A;  2LGR A;  4JLL A;  3Q6Z A;  4KSI A;  1ZR3 A;  5E3B A;  1GYT A;  5FSY A;  2XD7 A;  3EKE A;  3EWQ A;  4GVV A;  2BFR A;  2L8R A;  2EWB A;  2VRI A;  3V2B A;  4J5Q A;  2FAV A;  4JCA A;  1LCP A;  2JZF A;  3KZW A;  4ETJ A;  1TXZ A;  2JZD A;  3EJF A;  4GUA A;  4ZY2 A;  3ETI A;  3GQE A;  5FSV A;  2ACF A;  4KYB A;  2DX6 A;  2JZE A;  3VFQ A;  3KQX A;  4ZI6 A;  4JVV A;  3Q71 A;  1BLL E;  5FSX A;  3EWO A;  2AFC A;  4J5R A;  3IJ3 A;  2J9A A;  3KR5 A;  3EW5 A;  1HJZ A;  3H8E A;  2BFQ A;  5FSU A;  4R6T A;  3H8G A;  1LAM A;  1VHU A;  5AIL A;  1TY8 A;  2FXK A;  5CB5 A;  4K3N A;  3SIH A;  4ZY0 A;  3EWP A;  3PEI A;  3GPG A;  2KQV A;  1BPM A;  4GVW A;  4X2T A;  4UML A;  4ZX9 A;  3JRU A;  4R76 A;  1BPN A;  4J5S A;  4ZX8 A;  5CB3 A;  3EJG A;  3IIF A;  4IQY A;  3KQZ A;  2RNK A;  3IID A;  3GPQ A;  5CMS A;  1NJR A;  3GPO A;  5HIH A;  5HOL A;  4K0C A;  5FSZ A;  3KR4 A;  5DUS A;  1LAP A;  2X47 A;  4R7M A;  2FG1 A;  1SPV A;  3SIG A;  3H8F A;  2EEE A;  3GQO A;  1YD9 A;  1ZR5 A;  5D8N A;  4D86 A;  3V45 A;  4ZY1 A;  2W2G A;  4TU0 A;  3T8W A;  3SIJ A;  5CBM A; 
#chains in the Genus database with same CATH homology
 4ZYQ A;  4ABK A;  1LAN A;  3JZT A;  4ETK A;  4ESS A;  4JGK A;  3EWR A;  4ABL A;  4J4Z A;  3SII A;  2LGR A;  4JLL A;  3Q6Z A;  4KSI A;  1ZR3 A;  5E3B A;  1GYT A;  5FSY A;  2XD7 A;  3EKE A;  3EWQ A;  4GVV A;  2BFR A;  2L8R A;  2EWB A;  2VRI A;  3V2B A;  4J5Q A;  2FAV A;  4JCA A;  1LCP A;  3KZW A;  4ETJ A;  1TXZ A;  3EJF A;  4GUA A;  4ZY2 A;  3ETI A;  3GQE A;  5FSV A;  2ACF A;  4KYB A;  2DX6 A;  3VFQ A;  3KQX A;  4ZI6 A;  4JVV A;  3Q71 A;  1BLL E;  5FSX A;  3EWO A;  2AFC A;  4J5R A;  3IJ3 A;  2J9A A;  3KR5 A;  3EW5 A;  1HJZ A;  3H8E A;  2BFQ A;  5FSU A;  4R6T A;  3H8G A;  1LAM A;  1VHU A;  5AIL A;  1TY8 A;  2FXK A;  5CB5 A;  4K3N A;  3SIH A;  4ZY0 A;  3EWP A;  3PEI A;  3GPG A;  1BPM A;  4GVW A;  4X2T A;  4UML A;  4ZX9 A;  3JRU A;  4R76 A;  1BPN A;  4J5S A;  4ZX8 A;  5CB3 A;  3EJG A;  3IIF A;  4IQY A;  3KQZ A;  3IID A;  3GPQ A;  5CMS A;  1NJR A;  3GPO A;  5HIH A;  5HOL A;  4K0C A;  5FSZ A;  3KR4 A;  5DUS A;  1LAP A;  2X47 A;  4R7M A;  2FG1 A;  1SPV A;  3SIG A;  3H8F A;  2EEE A;  3GQO A;  1YD9 A;  1ZR5 A;  5D8N A;  4D86 A;  3V45 A;  4ZY1 A;  4TU0 A;  3T8W A;  3SIJ A;  5CBM A; 
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