4K0CA

Crystal structure of the computationally designed serine hydrolase. northeast structural genomics consortium (nesg) target or317
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
160
structure length
160
Chain Sequence
ARIRDVQGDITEFQGDAIVNAANNYLKLGAGVAGAILRKGGPSIQEECDRIGKIRVGEAAVTGAGNLPVRYVIHAAVLGDEPASLETVRKATKSALEKAVELGLKTVAFTVPGAWVGGLPAEAVRRVMVEEIKKAPDTLEVTGVHGTEKSAEACRRARLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Northeast Structural Genomics Consortium Target OR317
rcsb
molecule tags Structural genomics, unknown function
source organism Synthetic construct
molecule keywords designed serine hydrolase
total genus 50
structure length 160
sequence length 160
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4k0cA00
1GYTA 3KZWA 4ZI6A 2X47A 1ZR5A 4JGKA 3JRUA 3EWPA 1NJRA 2L8RA 3V2BA 4ABLA 1VHUA 1LAMA 3IIDA 4J5SA 1BPNA 3SIJA 3EWOA 5FSZA 2FXKA 3H8EA 5CB5A 1LCPA 4ZX9A 3EWRA 4J4ZA 5D8NA 3H8GA 4R6TA 4GUAA 4X2TA 3VFQA 5FSVA 4ABKA 1SPVA 4KSIA 5FSUA 1HJZA 4JLLA 4ETKA 4D86A 2FAVA 5FSYA 5FSXA 4R76A 4TU0A 3SIHA 2XD7A 4ZX8A 3SIGA 2FG1A 3KR4A 4J5QA 3KQXA 2LGRA 5AILA 4KYBA 5HOLA 4ZYQA 3T8WA 3KR5A 3Q71A 1LAPA 2VRIA 5CBMA 2DX6A 4ZY2A 4JCAA 5CMSA 2EEEA 1LANA 3IJ3A 4K3NA 4GVWA 4J5RA 4ZY0A 3GQEA 4ESSA 2J9AA 3EW5A 1TXZA 3H8FA 3EJGA 1YD9A 3IIFA 2ACFA 3EKEA 1BPMA 4ZY1A 2EWBA 3SIIA 1TY8A 5HIHA 5E3BA 4UMLA 4R7MA 4IQYA 4K0CA 1BLLE 2AFCA 3Q6ZA 2BFQA 4GVVA 3ETIA 3EJFA 4ETJA 3KQZA 3EWQA 3PEIA 3JZTA 3V45A 5CB3A 1ZR3A 2BFRA 3GPQA 4JVVA 3GPOA 3GPGA 5DUSA 3GQOA
chains in the Genus database with same CATH superfamily
1GYTA 3KZWA 4ZI6A 2X47A 1ZR5A 4JGKA 3JRUA 3EWPA 1NJRA 2L8RA 3V2BA 4ABLA 1VHUA 1LAMA 3IIDA 4J5SA 1BPNA 3SIJA 3EWOA 5FSZA 2FXKA 3H8EA 5CB5A 1LCPA 4ZX9A 3EWRA 4J4ZA 5D8NA 3H8GA 4R6TA 4GUAA 4X2TA 3VFQA 5FSVA 4ABKA 1SPVA 4KSIA 5FSUA 1HJZA 4JLLA 4ETKA 2RNKA 2KQVA 4D86A 2FAVA 5FSYA 5FSXA 4R76A 4TU0A 3SIHA 2XD7A 4ZX8A 3SIGA 2FG1A 3KR4A 4J5QA 3KQXA 2LGRA 2JZEA 5AILA 4KYBA 5HOLA 4ZYQA 3T8WA 3KR5A 3Q71A 1LAPA 2VRIA 5CBMA 2DX6A 4ZY2A 4JCAA 5CMSA 2EEEA 1LANA 2JZDA 3IJ3A 4K3NA 4GVWA 2W2GA 4J5RA 4ZY0A 3GQEA 4ESSA 2J9AA 3EW5A 1TXZA 3H8FA 3EJGA 1YD9A 3IIFA 2ACFA 3EKEA 1BPMA 4ZY1A 2EWBA 3SIIA 1TY8A 5HIHA 5E3BA 4UMLA 4R7MA 4IQYA 4K0CA 1BLLE 2AFCA 3Q6ZA 2BFQA 4GVVA 3ETIA 3EJFA 2WCTA 4ETJA 3KQZA 3EWQA 3PEIA 3JZTA 3V45A 2JZFA 5CB3A 1ZR3A 2BFRA 3GPQA 4JVVA 3GPOA 3GPGA 5DUSA 3GQOA
chains in the Genus database with same CATH topology
1GYTA 3KZWA 4ZI6A 2X47A 1ZR5A 4JGKA 3JRUA 3EWPA 1NJRA 2L8RA 3V2BA 4ABLA 1VHUA 1LAMA 3IIDA 4J5SA 1BPNA 3SIJA 3EWOA 5FSZA 2FXKA 3H8EA 5CB5A 1LCPA 4ZX9A 3EWRA 4J4ZA 5D8NA 3H8GA 4R6TA 4GUAA 4X2TA 3VFQA 5FSVA 4ABKA 1SPVA 4KSIA 5FSUA 1HJZA 4JLLA 4ETKA 4D86A 2FAVA 5FSYA 5FSXA 4R76A 4TU0A 3SIHA 2XD7A 4ZX8A 3SIGA 2FG1A 3KR4A 4J5QA 3KQXA 2LGRA 5AILA 4KYBA 5HOLA 4ZYQA 3T8WA 3KR5A 3Q71A 1LAPA 2VRIA 5CBMA 2DX6A 4ZY2A 4JCAA 5CMSA 2EEEA 1LANA 3IJ3A 4K3NA 4GVWA 4J5RA 4ZY0A 3GQEA 4ESSA 2J9AA 3EW5A 1TXZA 3H8FA 3EJGA 1YD9A 3IIFA 2ACFA 3EKEA 1BPMA 4ZY1A 2EWBA 3SIIA 1TY8A 5HIHA 5E3BA 4UMLA 4R7MA 4IQYA 4K0CA 1BLLE 2AFCA 3Q6ZA 2BFQA 4GVVA 3ETIA 3EJFA 4ETJA 3KQZA 3EWQA 3PEIA 3JZTA 3V45A 5CB3A 1ZR3A 2BFRA 3GPQA 4JVVA 3GPOA 3GPGA 5DUSA 3GQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GYT A;  3KZW A;  4ZI6 A;  2X47 A;  1ZR5 A;  4JGK A;  3JRU A;  3EWP A;  1NJR A;  2L8R A;  3V2B A;  4ABL A;  1VHU A;  1LAM A;  3IID A;  4J5S A;  1BPN A;  3SIJ A;  3EWO A;  5FSZ A;  2FXK A;  3H8E A;  5CB5 A;  1LCP A;  4ZX9 A;  3EWR A;  4J4Z A;  5D8N A;  3H8G A;  4R6T A;  4GUA A;  4X2T A;  3VFQ A;  5FSV A;  4ABK A;  1SPV A;  4KSI A;  5FSU A;  1HJZ A;  4JLL A;  4ETK A;  4D86 A;  2FAV A;  5FSY A;  5FSX A;  4R76 A;  4TU0 A;  3SIH A;  2XD7 A;  4ZX8 A;  3SIG A;  2FG1 A;  3KR4 A;  4J5Q A;  3KQX A;  2LGR A;  5AIL A;  4KYB A;  5HOL A;  4ZYQ A;  3T8W A;  3KR5 A;  3Q71 A;  1LAP A;  2VRI A;  5CBM A;  2DX6 A;  4ZY2 A;  4JCA A;  5CMS A;  2EEE A;  1LAN A;  3IJ3 A;  4K3N A;  4GVW A;  4J5R A;  4ZY0 A;  3GQE A;  4ESS A;  2J9A A;  3EW5 A;  1TXZ A;  3H8F A;  3EJG A;  1YD9 A;  3IIF A;  2ACF A;  3EKE A;  1BPM A;  4ZY1 A;  2EWB A;  3SII A;  1TY8 A;  5HIH A;  5E3B A;  4UML A;  4R7M A;  4IQY A;  4K0C A;  1BLL E;  2AFC A;  3Q6Z A;  2BFQ A;  4GVV A;  3ETI A;  3EJF A;  4ETJ A;  3KQZ A;  3EWQ A;  3PEI A;  3JZT A;  3V45 A;  5CB3 A;  1ZR3 A;  2BFR A;  3GPQ A;  4JVV A;  3GPO A;  3GPG A;  5DUS A;  3GQO A; 
#chains in the Genus database with same CATH topology
 1GYT A;  3KZW A;  4ZI6 A;  2X47 A;  1ZR5 A;  4JGK A;  3JRU A;  3EWP A;  1NJR A;  2L8R A;  3V2B A;  4ABL A;  1VHU A;  1LAM A;  3IID A;  4J5S A;  1BPN A;  3SIJ A;  3EWO A;  5FSZ A;  2FXK A;  3H8E A;  5CB5 A;  1LCP A;  4ZX9 A;  3EWR A;  4J4Z A;  5D8N A;  3H8G A;  4R6T A;  4GUA A;  4X2T A;  3VFQ A;  5FSV A;  4ABK A;  1SPV A;  4KSI A;  5FSU A;  1HJZ A;  4JLL A;  4ETK A;  2RNK A;  2KQV A;  4D86 A;  2FAV A;  5FSY A;  5FSX A;  4R76 A;  4TU0 A;  3SIH A;  2XD7 A;  4ZX8 A;  3SIG A;  2FG1 A;  3KR4 A;  4J5Q A;  3KQX A;  2LGR A;  2JZE A;  5AIL A;  4KYB A;  5HOL A;  4ZYQ A;  3T8W A;  3KR5 A;  3Q71 A;  1LAP A;  2VRI A;  5CBM A;  2DX6 A;  4ZY2 A;  4JCA A;  5CMS A;  2EEE A;  1LAN A;  2JZD A;  3IJ3 A;  4K3N A;  4GVW A;  2W2G A;  4J5R A;  4ZY0 A;  3GQE A;  4ESS A;  2J9A A;  3EW5 A;  1TXZ A;  3H8F A;  3EJG A;  1YD9 A;  3IIF A;  2ACF A;  3EKE A;  1BPM A;  4ZY1 A;  2EWB A;  3SII A;  1TY8 A;  5HIH A;  5E3B A;  4UML A;  4R7M A;  4IQY A;  4K0C A;  1BLL E;  2AFC A;  3Q6Z A;  2BFQ A;  4GVV A;  3ETI A;  3EJF A;  2WCT A;  4ETJ A;  3KQZ A;  3EWQ A;  3PEI A;  3JZT A;  3V45 A;  2JZF A;  5CB3 A;  1ZR3 A;  2BFR A;  3GPQ A;  4JVV A;  3GPO A;  3GPG A;  5DUS A;  3GQO A; 
#chains in the Genus database with same CATH homology
 1GYT A;  3KZW A;  4ZI6 A;  2X47 A;  1ZR5 A;  4JGK A;  3JRU A;  3EWP A;  1NJR A;  2L8R A;  3V2B A;  4ABL A;  1VHU A;  1LAM A;  3IID A;  4J5S A;  1BPN A;  3SIJ A;  3EWO A;  5FSZ A;  2FXK A;  3H8E A;  5CB5 A;  1LCP A;  4ZX9 A;  3EWR A;  4J4Z A;  5D8N A;  3H8G A;  4R6T A;  4GUA A;  4X2T A;  3VFQ A;  5FSV A;  4ABK A;  1SPV A;  4KSI A;  5FSU A;  1HJZ A;  4JLL A;  4ETK A;  4D86 A;  2FAV A;  5FSY A;  5FSX A;  4R76 A;  4TU0 A;  3SIH A;  2XD7 A;  4ZX8 A;  3SIG A;  2FG1 A;  3KR4 A;  4J5Q A;  3KQX A;  2LGR A;  5AIL A;  4KYB A;  5HOL A;  4ZYQ A;  3T8W A;  3KR5 A;  3Q71 A;  1LAP A;  2VRI A;  5CBM A;  2DX6 A;  4ZY2 A;  4JCA A;  5CMS A;  2EEE A;  1LAN A;  3IJ3 A;  4K3N A;  4GVW A;  4J5R A;  4ZY0 A;  3GQE A;  4ESS A;  2J9A A;  3EW5 A;  1TXZ A;  3H8F A;  3EJG A;  1YD9 A;  3IIF A;  2ACF A;  3EKE A;  1BPM A;  4ZY1 A;  2EWB A;  3SII A;  1TY8 A;  5HIH A;  5E3B A;  4UML A;  4R7M A;  4IQY A;  4K0C A;  1BLL E;  2AFC A;  3Q6Z A;  2BFQ A;  4GVV A;  3ETI A;  3EJF A;  4ETJ A;  3KQZ A;  3EWQ A;  3PEI A;  3JZT A;  3V45 A;  5CB3 A;  1ZR3 A;  2BFR A;  3GPQ A;  4JVV A;  3GPO A;  3GPG A;  5DUS A;  3GQO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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