4TU0A

Crystal structure of chikungunya virus nsp3 macro domain in complex with a 2'-5' oligoadenylate trimer
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
162
structure length
160
Chain Sequence
HHAPSYVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
rcsb
molecule tags Viral protein
source organism Chikungunya virus
molecule keywords Non-structural polyprotein 3
total genus 53
structure length 160
sequence length 162
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.19: Polynucleotide adenylyltransferase.
pdb deposition date 2014-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4tu0A00
1LAMA 3SIIA 3EWOA 2X47A 5CMSA 5AILA 4ZY2A 3H8GA 4GUAA 2VRIA 5CB3A 4R6TA 4J5RA 2ACFA 3KR5A 1BLLE 4GVWA 2AFCA 2XD7A 3ETIA 3EKEA 2FG1A 5FSXA 3JZTA 3IIFA 3H8EA 4JVVA 3GQEA 4ABLA 5FSYA 3EWPA 5FSZA 4ZYQA 1LCPA 5HOLA 1HJZA 5HIHA 4R7MA 5D8NA 3Q71A 2DX6A 3Q6ZA 5E3BA 3IIDA 3EJGA 3PEIA 3VFQA 1BPMA 3H8FA 3GPQA 4ESSA 1LAPA 1VHUA 2BFQA 3KQZA 4TU0A 3JRUA 2FAVA 1TXZA 4X2TA 4ZX8A 4ZY0A 4JLLA 2EWBA 3GPOA 1BPNA 1YD9A 3EJFA 3SIJA 4J5SA 4J5QA 4JCAA 4ZI6A 2L8RA 3GQOA 1GYTA 4R76A 5CB5A 4ETJA 4ZX9A 3V45A 2FXKA 3KR4A 3EWQA 1ZR5A 3SIHA 3EWRA 5CBMA 4D86A 3EW5A 3IJ3A 4GVVA 3T8WA 2BFRA 2J9AA 2LGRA 5DUSA 4KSIA 1NJRA 4IQYA 4ABKA 1LANA 4K3NA 4J4ZA 1TY8A 3GPGA 4K0CA 4ZY1A 3KQXA 3SIGA 5FSVA 1ZR3A 3V2BA 1SPVA 2EEEA 4KYBA 4JGKA 3KZWA 5FSUA 4UMLA 4ETKA
chains in the Genus database with same CATH superfamily
1LAMA 3SIIA 3EWOA 2X47A 5CMSA 5AILA 4ZY2A 3H8GA 4GUAA 2VRIA 5CB3A 4R6TA 4J5RA 2ACFA 3KR5A 1BLLE 4GVWA 2AFCA 2XD7A 3ETIA 3EKEA 2FG1A 5FSXA 3JZTA 3IIFA 3H8EA 4JVVA 3GQEA 4ABLA 5FSYA 3EWPA 5FSZA 4ZYQA 1LCPA 5HOLA 1HJZA 5HIHA 4R7MA 5D8NA 3Q71A 2W2GA 2DX6A 3Q6ZA 5E3BA 3IIDA 3EJGA 3PEIA 2RNKA 3VFQA 1BPMA 3H8FA 2WCTA 3GPQA 4ESSA 1LAPA 1VHUA 2JZDA 2BFQA 3KQZA 4TU0A 3JRUA 2FAVA 1TXZA 4X2TA 4ZX8A 4ZY0A 2KQVA 4JLLA 2EWBA 3GPOA 1BPNA 1YD9A 3EJFA 3SIJA 4J5SA 4J5QA 4JCAA 2JZFA 4ZI6A 2L8RA 3GQOA 1GYTA 4R76A 5CB5A 4ETJA 4ZX9A 3V45A 2FXKA 3KR4A 3EWQA 1ZR5A 3SIHA 3EWRA 5CBMA 4D86A 3EW5A 3IJ3A 4GVVA 3T8WA 2BFRA 2J9AA 2LGRA 5DUSA 1NJRA 4KSIA 4IQYA 4ABKA 1LANA 4K3NA 4J4ZA 1TY8A 3GPGA 4K0CA 4ZY1A 3KQXA 3SIGA 5FSVA 1ZR3A 3V2BA 2JZEA 1SPVA 2EEEA 4KYBA 4JGKA 3KZWA 5FSUA 4UMLA 4ETKA
chains in the Genus database with same CATH topology
1LAMA 3SIIA 3EWOA 2X47A 5CMSA 5AILA 4ZY2A 3H8GA 4GUAA 2VRIA 5CB3A 4R6TA 4J5RA 2ACFA 3KR5A 1BLLE 4GVWA 2AFCA 2XD7A 3ETIA 3EKEA 2FG1A 5FSXA 3JZTA 3IIFA 3H8EA 4JVVA 3GQEA 4ABLA 5FSYA 3EWPA 5FSZA 4ZYQA 1LCPA 5HOLA 1HJZA 5HIHA 4R7MA 5D8NA 3Q71A 2DX6A 3Q6ZA 5E3BA 3IIDA 3EJGA 3PEIA 3VFQA 1BPMA 3H8FA 3GPQA 4ESSA 1LAPA 1VHUA 2BFQA 3KQZA 4TU0A 3JRUA 2FAVA 1TXZA 4X2TA 4ZX8A 4ZY0A 4JLLA 2EWBA 3GPOA 1BPNA 1YD9A 3EJFA 3SIJA 4J5SA 4J5QA 4JCAA 4ZI6A 2L8RA 3GQOA 1GYTA 4R76A 5CB5A 4ETJA 4ZX9A 3V45A 2FXKA 3KR4A 3EWQA 1ZR5A 3SIHA 3EWRA 5CBMA 4D86A 3EW5A 3IJ3A 4GVVA 3T8WA 2BFRA 2J9AA 2LGRA 5DUSA 4KSIA 1NJRA 4IQYA 4ABKA 1LANA 4K3NA 4J4ZA 1TY8A 3GPGA 4K0CA 4ZY1A 3KQXA 3SIGA 5FSVA 1ZR3A 3V2BA 1SPVA 2EEEA 4KYBA 4JGKA 3KZWA 5FSUA 4UMLA 4ETKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LAM A;  3SII A;  3EWO A;  2X47 A;  5CMS A;  5AIL A;  4ZY2 A;  3H8G A;  4GUA A;  2VRI A;  5CB3 A;  4R6T A;  4J5R A;  2ACF A;  3KR5 A;  1BLL E;  4GVW A;  2AFC A;  2XD7 A;  3ETI A;  3EKE A;  2FG1 A;  5FSX A;  3JZT A;  3IIF A;  3H8E A;  4JVV A;  3GQE A;  4ABL A;  5FSY A;  3EWP A;  5FSZ A;  4ZYQ A;  1LCP A;  5HOL A;  1HJZ A;  5HIH A;  4R7M A;  5D8N A;  3Q71 A;  2DX6 A;  3Q6Z A;  5E3B A;  3IID A;  3EJG A;  3PEI A;  3VFQ A;  1BPM A;  3H8F A;  3GPQ A;  4ESS A;  1LAP A;  1VHU A;  2BFQ A;  3KQZ A;  4TU0 A;  3JRU A;  2FAV A;  1TXZ A;  4X2T A;  4ZX8 A;  4ZY0 A;  4JLL A;  2EWB A;  3GPO A;  1BPN A;  1YD9 A;  3EJF A;  3SIJ A;  4J5S A;  4J5Q A;  4JCA A;  4ZI6 A;  2L8R A;  3GQO A;  1GYT A;  4R76 A;  5CB5 A;  4ETJ A;  4ZX9 A;  3V45 A;  2FXK A;  3KR4 A;  3EWQ A;  1ZR5 A;  3SIH A;  3EWR A;  5CBM A;  4D86 A;  3EW5 A;  3IJ3 A;  4GVV A;  3T8W A;  2BFR A;  2J9A A;  2LGR A;  5DUS A;  4KSI A;  1NJR A;  4IQY A;  4ABK A;  1LAN A;  4K3N A;  4J4Z A;  1TY8 A;  3GPG A;  4K0C A;  4ZY1 A;  3KQX A;  3SIG A;  5FSV A;  1ZR3 A;  3V2B A;  1SPV A;  2EEE A;  4KYB A;  4JGK A;  3KZW A;  5FSU A;  4UML A;  4ETK A; 
#chains in the Genus database with same CATH topology
 1LAM A;  3SII A;  3EWO A;  2X47 A;  5CMS A;  5AIL A;  4ZY2 A;  3H8G A;  4GUA A;  2VRI A;  5CB3 A;  4R6T A;  4J5R A;  2ACF A;  3KR5 A;  1BLL E;  4GVW A;  2AFC A;  2XD7 A;  3ETI A;  3EKE A;  2FG1 A;  5FSX A;  3JZT A;  3IIF A;  3H8E A;  4JVV A;  3GQE A;  4ABL A;  5FSY A;  3EWP A;  5FSZ A;  4ZYQ A;  1LCP A;  5HOL A;  1HJZ A;  5HIH A;  4R7M A;  5D8N A;  3Q71 A;  2W2G A;  2DX6 A;  3Q6Z A;  5E3B A;  3IID A;  3EJG A;  3PEI A;  2RNK A;  3VFQ A;  1BPM A;  3H8F A;  2WCT A;  3GPQ A;  4ESS A;  1LAP A;  1VHU A;  2JZD A;  2BFQ A;  3KQZ A;  4TU0 A;  3JRU A;  2FAV A;  1TXZ A;  4X2T A;  4ZX8 A;  4ZY0 A;  2KQV A;  4JLL A;  2EWB A;  3GPO A;  1BPN A;  1YD9 A;  3EJF A;  3SIJ A;  4J5S A;  4J5Q A;  4JCA A;  2JZF A;  4ZI6 A;  2L8R A;  3GQO A;  1GYT A;  4R76 A;  5CB5 A;  4ETJ A;  4ZX9 A;  3V45 A;  2FXK A;  3KR4 A;  3EWQ A;  1ZR5 A;  3SIH A;  3EWR A;  5CBM A;  4D86 A;  3EW5 A;  3IJ3 A;  4GVV A;  3T8W A;  2BFR A;  2J9A A;  2LGR A;  5DUS A;  1NJR A;  4KSI A;  4IQY A;  4ABK A;  1LAN A;  4K3N A;  4J4Z A;  1TY8 A;  3GPG A;  4K0C A;  4ZY1 A;  3KQX A;  3SIG A;  5FSV A;  1ZR3 A;  3V2B A;  2JZE A;  1SPV A;  2EEE A;  4KYB A;  4JGK A;  3KZW A;  5FSU A;  4UML A;  4ETK A; 
#chains in the Genus database with same CATH homology
 1LAM A;  3SII A;  3EWO A;  2X47 A;  5CMS A;  5AIL A;  4ZY2 A;  3H8G A;  4GUA A;  2VRI A;  5CB3 A;  4R6T A;  4J5R A;  2ACF A;  3KR5 A;  1BLL E;  4GVW A;  2AFC A;  2XD7 A;  3ETI A;  3EKE A;  2FG1 A;  5FSX A;  3JZT A;  3IIF A;  3H8E A;  4JVV A;  3GQE A;  4ABL A;  5FSY A;  3EWP A;  5FSZ A;  4ZYQ A;  1LCP A;  5HOL A;  1HJZ A;  5HIH A;  4R7M A;  5D8N A;  3Q71 A;  2DX6 A;  3Q6Z A;  5E3B A;  3IID A;  3EJG A;  3PEI A;  3VFQ A;  1BPM A;  3H8F A;  3GPQ A;  4ESS A;  1LAP A;  1VHU A;  2BFQ A;  3KQZ A;  4TU0 A;  3JRU A;  2FAV A;  1TXZ A;  4X2T A;  4ZX8 A;  4ZY0 A;  4JLL A;  2EWB A;  3GPO A;  1BPN A;  1YD9 A;  3EJF A;  3SIJ A;  4J5S A;  4J5Q A;  4JCA A;  4ZI6 A;  2L8R A;  3GQO A;  1GYT A;  4R76 A;  5CB5 A;  4ETJ A;  4ZX9 A;  3V45 A;  2FXK A;  3KR4 A;  3EWQ A;  1ZR5 A;  3SIH A;  3EWR A;  5CBM A;  4D86 A;  3EW5 A;  3IJ3 A;  4GVV A;  3T8W A;  2BFR A;  2J9A A;  2LGR A;  5DUS A;  4KSI A;  1NJR A;  4IQY A;  4ABK A;  1LAN A;  4K3N A;  4J4Z A;  1TY8 A;  3GPG A;  4K0C A;  4ZY1 A;  3KQX A;  3SIG A;  5FSV A;  1ZR3 A;  3V2B A;  1SPV A;  2EEE A;  4KYB A;  4JGK A;  3KZW A;  5FSU A;  4UML A;  4ETK A; 
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similar chains in the Genus database (?% sequence similarity)
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