4D86A

Human parp14 (artd8, bal2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
374
Chain Sequence
KCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Poly [ADP-ribose] polymerase 14
total genus 137
structure length 374
sequence length 401
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4d86A02
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4d86A01
5DUSA 2XD7A 3EWQA 3JRUA 4ZY0A 3GPOA 2BFQA 5FSVA 5CBMA 3EJFA 4ETJA 5CB3A 3EWRA 3SIGA 5FSUA 4J5QA 1BPNA 3IJ3A 3KR5A 4R76A 4KYBA 1ZR3A 3H8FA 4UMLA 2FXKA 5FSXA 3EWOA 3H8EA 4ZY2A 4ABKA 3SIHA 1YD9A 3IIDA 3KZWA 3IIFA 3KQXA 4ZYQA 3KR4A 4D86A 4ZI6A 5CB5A 3SIJA 3GQOA 2LGRA 2FAVA 3EWPA 4J4ZA 3VFQA 3PEIA 1HJZA 3GPQA 5HOLA 3EJGA 4ETKA 4J5SA 4JCAA 4K0CA 3V2BA 5HIHA 4ABLA 1LCPA 4GVVA 4J5RA 2FG1A 4IQYA 3KQZA 3GQEA 4JVVA 3T8WA 1LAMA 4ZY1A 1BPMA 2ACFA 3JZTA 3EKEA 5E3BA 5FSZA 1TXZA 3SIIA 3Q71A 2J9AA 2AFCA 2VRIA 2L8RA 2EEEA 4R6TA 2BFRA 2DX6A 1BLLE 1LANA 5FSYA 4X2TA 4JGKA 1NJRA 5D8NA 3GPGA 3ETIA 3EW5A 4TU0A 1LAPA 3H8GA 2X47A 4ZX9A 3V45A 4ZX8A 4KSIA 1ZR5A 4R7MA 1VHUA 3Q6ZA 2EWBA 4GUAA 5AILA 4K3NA 1TY8A 5CMSA 1GYTA 4ESSA 1SPVA 4JLLA 4GVWA
chains in the Genus database with same CATH superfamily
5DUSA 2JZEA 2XD7A 3EWQA 3JRUA 4ZY0A 3GPOA 2BFQA 2KQVA 5FSVA 5CBMA 3EJFA 4ETJA 5CB3A 3EWRA 3SIGA 5FSUA 4J5QA 1BPNA 3IJ3A 3KR5A 4R76A 4KYBA 2RNKA 1ZR3A 3H8FA 4UMLA 2FXKA 5FSXA 3EWOA 3H8EA 4ZY2A 4ABKA 3SIHA 1YD9A 3IIDA 3KZWA 3IIFA 3KQXA 4ZYQA 3KR4A 4D86A 2JZFA 4ZI6A 5CB5A 3SIJA 3GQOA 2LGRA 2FAVA 3EWPA 4J4ZA 3VFQA 3PEIA 1HJZA 3GPQA 5HOLA 3EJGA 4ETKA 4J5SA 4JCAA 4K0CA 3V2BA 5HIHA 4ABLA 1LCPA 4GVVA 4J5RA 2FG1A 4IQYA 3KQZA 3GQEA 4JVVA 3T8WA 1LAMA 4ZY1A 1BPMA 2ACFA 3JZTA 3EKEA 5E3BA 5FSZA 1TXZA 2JZDA 3SIIA 3Q71A 2J9AA 2AFCA 2VRIA 2L8RA 2EEEA 4R6TA 2BFRA 2DX6A 1BLLE 1LANA 5FSYA 4X2TA 4JGKA 1NJRA 5D8NA 3GPGA 3ETIA 2WCTA 3EW5A 4TU0A 1LAPA 3H8GA 2X47A 4ZX9A 3V45A 4ZX8A 4KSIA 1ZR5A 4R7MA 1VHUA 3Q6ZA 2EWBA 4GUAA 5AILA 4K3NA 1TY8A 5CMSA 2W2GA 1GYTA 4ESSA 1SPVA 4JLLA 4GVWA
chains in the Genus database with same CATH topology
5DUSA 2XD7A 3EWQA 3JRUA 4ZY0A 3GPOA 2BFQA 5FSVA 5CBMA 3EJFA 4ETJA 5CB3A 3EWRA 3SIGA 5FSUA 4J5QA 1BPNA 3IJ3A 3KR5A 4R76A 4KYBA 1ZR3A 3H8FA 4UMLA 2FXKA 5FSXA 3EWOA 3H8EA 4ZY2A 4ABKA 3SIHA 1YD9A 3IIDA 3KZWA 3IIFA 3KQXA 4ZYQA 3KR4A 4D86A 4ZI6A 5CB5A 3SIJA 3GQOA 2LGRA 2FAVA 3EWPA 4J4ZA 3VFQA 3PEIA 1HJZA 3GPQA 5HOLA 3EJGA 4ETKA 4J5SA 4JCAA 4K0CA 3V2BA 5HIHA 4ABLA 1LCPA 4GVVA 4J5RA 2FG1A 4IQYA 3KQZA 3GQEA 4JVVA 3T8WA 1LAMA 4ZY1A 1BPMA 2ACFA 3JZTA 3EKEA 5E3BA 5FSZA 1TXZA 3SIIA 3Q71A 2J9AA 2AFCA 2VRIA 2L8RA 2EEEA 4R6TA 2BFRA 2DX6A 1BLLE 1LANA 5FSYA 4X2TA 4JGKA 1NJRA 5D8NA 3GPGA 3ETIA 3EW5A 4TU0A 1LAPA 3H8GA 2X47A 4ZX9A 3V45A 4ZX8A 4KSIA 1ZR5A 4R7MA 1VHUA 3Q6ZA 2EWBA 4GUAA 5AILA 4K3NA 1TY8A 5CMSA 1GYTA 4ESSA 1SPVA 4JLLA 4GVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DUS A;  2XD7 A;  3EWQ A;  3JRU A;  4ZY0 A;  3GPO A;  2BFQ A;  5FSV A;  5CBM A;  3EJF A;  4ETJ A;  5CB3 A;  3EWR A;  3SIG A;  5FSU A;  4J5Q A;  1BPN A;  3IJ3 A;  3KR5 A;  4R76 A;  4KYB A;  1ZR3 A;  3H8F A;  4UML A;  2FXK A;  5FSX A;  3EWO A;  3H8E A;  4ZY2 A;  4ABK A;  3SIH A;  1YD9 A;  3IID A;  3KZW A;  3IIF A;  3KQX A;  4ZYQ A;  3KR4 A;  4D86 A;  4ZI6 A;  5CB5 A;  3SIJ A;  3GQO A;  2LGR A;  2FAV A;  3EWP A;  4J4Z A;  3VFQ A;  3PEI A;  1HJZ A;  3GPQ A;  5HOL A;  3EJG A;  4ETK A;  4J5S A;  4JCA A;  4K0C A;  3V2B A;  5HIH A;  4ABL A;  1LCP A;  4GVV A;  4J5R A;  2FG1 A;  4IQY A;  3KQZ A;  3GQE A;  4JVV A;  3T8W A;  1LAM A;  4ZY1 A;  1BPM A;  2ACF A;  3JZT A;  3EKE A;  5E3B A;  5FSZ A;  1TXZ A;  3SII A;  3Q71 A;  2J9A A;  2AFC A;  2VRI A;  2L8R A;  2EEE A;  4R6T A;  2BFR A;  2DX6 A;  1BLL E;  1LAN A;  5FSY A;  4X2T A;  4JGK A;  1NJR A;  5D8N A;  3GPG A;  3ETI A;  3EW5 A;  4TU0 A;  1LAP A;  3H8G A;  2X47 A;  4ZX9 A;  3V45 A;  4ZX8 A;  4KSI A;  1ZR5 A;  4R7M A;  1VHU A;  3Q6Z A;  2EWB A;  4GUA A;  5AIL A;  4K3N A;  1TY8 A;  5CMS A;  1GYT A;  4ESS A;  1SPV A;  4JLL A;  4GVW A; 
#chains in the Genus database with same CATH topology
 5DUS A;  2JZE A;  2XD7 A;  3EWQ A;  3JRU A;  4ZY0 A;  3GPO A;  2BFQ A;  2KQV A;  5FSV A;  5CBM A;  3EJF A;  4ETJ A;  5CB3 A;  3EWR A;  3SIG A;  5FSU A;  4J5Q A;  1BPN A;  3IJ3 A;  3KR5 A;  4R76 A;  4KYB A;  2RNK A;  1ZR3 A;  3H8F A;  4UML A;  2FXK A;  5FSX A;  3EWO A;  3H8E A;  4ZY2 A;  4ABK A;  3SIH A;  1YD9 A;  3IID A;  3KZW A;  3IIF A;  3KQX A;  4ZYQ A;  3KR4 A;  4D86 A;  2JZF A;  4ZI6 A;  5CB5 A;  3SIJ A;  3GQO A;  2LGR A;  2FAV A;  3EWP A;  4J4Z A;  3VFQ A;  3PEI A;  1HJZ A;  3GPQ A;  5HOL A;  3EJG A;  4ETK A;  4J5S A;  4JCA A;  4K0C A;  3V2B A;  5HIH A;  4ABL A;  1LCP A;  4GVV A;  4J5R A;  2FG1 A;  4IQY A;  3KQZ A;  3GQE A;  4JVV A;  3T8W A;  1LAM A;  4ZY1 A;  1BPM A;  2ACF A;  3JZT A;  3EKE A;  5E3B A;  5FSZ A;  1TXZ A;  2JZD A;  3SII A;  3Q71 A;  2J9A A;  2AFC A;  2VRI A;  2L8R A;  2EEE A;  4R6T A;  2BFR A;  2DX6 A;  1BLL E;  1LAN A;  5FSY A;  4X2T A;  4JGK A;  1NJR A;  5D8N A;  3GPG A;  3ETI A;  2WCT A;  3EW5 A;  4TU0 A;  1LAP A;  3H8G A;  2X47 A;  4ZX9 A;  3V45 A;  4ZX8 A;  4KSI A;  1ZR5 A;  4R7M A;  1VHU A;  3Q6Z A;  2EWB A;  4GUA A;  5AIL A;  4K3N A;  1TY8 A;  5CMS A;  2W2G A;  1GYT A;  4ESS A;  1SPV A;  4JLL A;  4GVW A; 
#chains in the Genus database with same CATH homology
 5DUS A;  2XD7 A;  3EWQ A;  3JRU A;  4ZY0 A;  3GPO A;  2BFQ A;  5FSV A;  5CBM A;  3EJF A;  4ETJ A;  5CB3 A;  3EWR A;  3SIG A;  5FSU A;  4J5Q A;  1BPN A;  3IJ3 A;  3KR5 A;  4R76 A;  4KYB A;  1ZR3 A;  3H8F A;  4UML A;  2FXK A;  5FSX A;  3EWO A;  3H8E A;  4ZY2 A;  4ABK A;  3SIH A;  1YD9 A;  3IID A;  3KZW A;  3IIF A;  3KQX A;  4ZYQ A;  3KR4 A;  4D86 A;  4ZI6 A;  5CB5 A;  3SIJ A;  3GQO A;  2LGR A;  2FAV A;  3EWP A;  4J4Z A;  3VFQ A;  3PEI A;  1HJZ A;  3GPQ A;  5HOL A;  3EJG A;  4ETK A;  4J5S A;  4JCA A;  4K0C A;  3V2B A;  5HIH A;  4ABL A;  1LCP A;  4GVV A;  4J5R A;  2FG1 A;  4IQY A;  3KQZ A;  3GQE A;  4JVV A;  3T8W A;  1LAM A;  4ZY1 A;  1BPM A;  2ACF A;  3JZT A;  3EKE A;  5E3B A;  5FSZ A;  1TXZ A;  3SII A;  3Q71 A;  2J9A A;  2AFC A;  2VRI A;  2L8R A;  2EEE A;  4R6T A;  2BFR A;  2DX6 A;  1BLL E;  1LAN A;  5FSY A;  4X2T A;  4JGK A;  1NJR A;  5D8N A;  3GPG A;  3ETI A;  3EW5 A;  4TU0 A;  1LAP A;  3H8G A;  2X47 A;  4ZX9 A;  3V45 A;  4ZX8 A;  4KSI A;  1ZR5 A;  4R7M A;  1VHU A;  3Q6Z A;  2EWB A;  4GUA A;  5AIL A;  4K3N A;  1TY8 A;  5CMS A;  1GYT A;  4ESS A;  1SPV A;  4JLL A;  4GVW A; 
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