4TU0A

Crystal structure of chikungunya virus nsp3 macro domain in complex with a 2'-5' oligoadenylate trimer
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
162
structure length
160
Chain Sequence
HHAPSYVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
rcsb
molecule tags Viral protein
source organism Chikungunya virus
molecule keywords Non-structural polyprotein 3
total genus 53
structure length 160
sequence length 162
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.19: Polynucleotide adenylyltransferase.
pdb deposition date 2014-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4tu0A00
3V2BA 3EW5A 1SPVA 4ZX8A 5CBMA 4ZY1A 2FG1A 4JLLA 4ZI6A 3H8EA 5HIHA 2BFRA 4UMLA 3SIHA 5CB5A 1LANA 3KZWA 4KYBA 3PEIA 1BPMA 3EJFA 3KR4A 3IJ3A 4J5RA 3KQZA 5FSVA 5FSYA 4X2TA 4TU0A 2EWBA 4KSIA 4ZY2A 2XD7A 3GPQA 1NJRA 3GQEA 1YD9A 2L8RA 4J5SA 3EWQA 5D8NA 3EWPA 3GPOA 4ETJA 3SIIA 2VRIA 5E3BA 4ETKA 3ETIA 3JRUA 3KQXA 4JGKA 3EWOA 4ESSA 1LAPA 3EWRA 4JCAA 4K3NA 1TY8A 4R6TA 2FXKA 4GVWA 1VHUA 3GPGA 4JVVA 3KR5A 4ZX9A 3JZTA 4J4ZA 1HJZA 3IIDA 3SIGA 5AILA 1TXZA 4R7MA 3IIFA 2EEEA 4GUAA 5FSUA 3H8GA 3EJGA 5CMSA 2DX6A 2ACFA 4ZY0A 4J5QA 2J9AA 3Q6ZA 1ZR5A 4GVVA 2LGRA 3VFQA 2X47A 4IQYA 5HOLA 5FSXA 5FSZA 4ZYQA 2AFCA 1LCPA 3SIJA 3V45A 4R76A 1BPNA 1BLLE 3GQOA 4D86A 3H8FA 1LAMA 4K0CA 5CB3A 3T8WA 1GYTA 2FAVA 1ZR3A 2BFQA 4ABLA 3Q71A 4ABKA 5DUSA 3EKEA
chains in the Genus database with same CATH superfamily
3V2BA 3EW5A 2JZEA 1SPVA 2JZFA 4ZX8A 5CBMA 4ZY1A 2FG1A 4JLLA 2JZDA 4ZI6A 3H8EA 5HIHA 2BFRA 4UMLA 3SIHA 5CB5A 1LANA 3KZWA 4KYBA 3PEIA 1BPMA 3EJFA 3KR4A 3IJ3A 2WCTA 4J5RA 3KQZA 5FSVA 5FSYA 4X2TA 4TU0A 2EWBA 4KSIA 4ZY2A 2XD7A 3GPQA 2KQVA 1NJRA 3GQEA 1YD9A 2L8RA 4J5SA 3EWQA 5D8NA 3EWPA 3GPOA 4ETJA 3SIIA 2VRIA 2W2GA 5E3BA 4ETKA 3KQXA 3ETIA 3JRUA 3EWOA 4JGKA 4ESSA 1LAPA 3EWRA 4JCAA 4K3NA 1TY8A 4R6TA 2FXKA 4GVWA 1VHUA 3GPGA 4JVVA 3KR5A 4ZX9A 3JZTA 4J4ZA 1HJZA 3IIDA 3SIGA 5AILA 1TXZA 4R7MA 3IIFA 2EEEA 4GUAA 5FSUA 3H8GA 3EJGA 5CMSA 2DX6A 2ACFA 4ZY0A 4J5QA 2J9AA 3Q6ZA 1ZR5A 4GVVA 2LGRA 3VFQA 2X47A 4IQYA 5HOLA 5FSXA 5FSZA 4ZYQA 2AFCA 1LCPA 3SIJA 3V45A 4R76A 1BPNA 1BLLE 3GQOA 4D86A 3H8FA 1LAMA 4K0CA 5CB3A 3T8WA 1GYTA 2FAVA 2RNKA 1ZR3A 2BFQA 4ABLA 3Q71A 4ABKA 5DUSA 3EKEA
chains in the Genus database with same CATH topology
3V2BA 3EW5A 1SPVA 4ZX8A 5CBMA 4ZY1A 2FG1A 4JLLA 4ZI6A 3H8EA 5HIHA 2BFRA 4UMLA 3SIHA 5CB5A 1LANA 3KZWA 4KYBA 3PEIA 1BPMA 3EJFA 3KR4A 3IJ3A 4J5RA 3KQZA 5FSVA 5FSYA 4X2TA 4TU0A 2EWBA 4KSIA 4ZY2A 2XD7A 3GPQA 1NJRA 3GQEA 1YD9A 2L8RA 4J5SA 3EWQA 5D8NA 3EWPA 3GPOA 4ETJA 3SIIA 2VRIA 5E3BA 4ETKA 3ETIA 3JRUA 3KQXA 4JGKA 3EWOA 4ESSA 1LAPA 3EWRA 4JCAA 4K3NA 1TY8A 4R6TA 2FXKA 4GVWA 1VHUA 3GPGA 4JVVA 3KR5A 4ZX9A 3JZTA 4J4ZA 1HJZA 3IIDA 3SIGA 5AILA 1TXZA 4R7MA 3IIFA 2EEEA 4GUAA 5FSUA 3H8GA 3EJGA 5CMSA 2DX6A 2ACFA 4ZY0A 4J5QA 2J9AA 3Q6ZA 1ZR5A 4GVVA 2LGRA 3VFQA 2X47A 4IQYA 5HOLA 5FSXA 5FSZA 4ZYQA 2AFCA 1LCPA 3SIJA 3V45A 4R76A 1BPNA 1BLLE 3GQOA 4D86A 3H8FA 1LAMA 4K0CA 5CB3A 3T8WA 1GYTA 2FAVA 1ZR3A 2BFQA 4ABLA 3Q71A 4ABKA 5DUSA 3EKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V2B A;  3EW5 A;  1SPV A;  4ZX8 A;  5CBM A;  4ZY1 A;  2FG1 A;  4JLL A;  4ZI6 A;  3H8E A;  5HIH A;  2BFR A;  4UML A;  3SIH A;  5CB5 A;  1LAN A;  3KZW A;  4KYB A;  3PEI A;  1BPM A;  3EJF A;  3KR4 A;  3IJ3 A;  4J5R A;  3KQZ A;  5FSV A;  5FSY A;  4X2T A;  4TU0 A;  2EWB A;  4KSI A;  4ZY2 A;  2XD7 A;  3GPQ A;  1NJR A;  3GQE A;  1YD9 A;  2L8R A;  4J5S A;  3EWQ A;  5D8N A;  3EWP A;  3GPO A;  4ETJ A;  3SII A;  2VRI A;  5E3B A;  4ETK A;  3ETI A;  3JRU A;  3KQX A;  4JGK A;  3EWO A;  4ESS A;  1LAP A;  3EWR A;  4JCA A;  4K3N A;  1TY8 A;  4R6T A;  2FXK A;  4GVW A;  1VHU A;  3GPG A;  4JVV A;  3KR5 A;  4ZX9 A;  3JZT A;  4J4Z A;  1HJZ A;  3IID A;  3SIG A;  5AIL A;  1TXZ A;  4R7M A;  3IIF A;  2EEE A;  4GUA A;  5FSU A;  3H8G A;  3EJG A;  5CMS A;  2DX6 A;  2ACF A;  4ZY0 A;  4J5Q A;  2J9A A;  3Q6Z A;  1ZR5 A;  4GVV A;  2LGR A;  3VFQ A;  2X47 A;  4IQY A;  5HOL A;  5FSX A;  5FSZ A;  4ZYQ A;  2AFC A;  1LCP A;  3SIJ A;  3V45 A;  4R76 A;  1BPN A;  1BLL E;  3GQO A;  4D86 A;  3H8F A;  1LAM A;  4K0C A;  5CB3 A;  3T8W A;  1GYT A;  2FAV A;  1ZR3 A;  2BFQ A;  4ABL A;  3Q71 A;  4ABK A;  5DUS A;  3EKE A; 
#chains in the Genus database with same CATH topology
 3V2B A;  3EW5 A;  2JZE A;  1SPV A;  2JZF A;  4ZX8 A;  5CBM A;  4ZY1 A;  2FG1 A;  4JLL A;  2JZD A;  4ZI6 A;  3H8E A;  5HIH A;  2BFR A;  4UML A;  3SIH A;  5CB5 A;  1LAN A;  3KZW A;  4KYB A;  3PEI A;  1BPM A;  3EJF A;  3KR4 A;  3IJ3 A;  2WCT A;  4J5R A;  3KQZ A;  5FSV A;  5FSY A;  4X2T A;  4TU0 A;  2EWB A;  4KSI A;  4ZY2 A;  2XD7 A;  3GPQ A;  2KQV A;  1NJR A;  3GQE A;  1YD9 A;  2L8R A;  4J5S A;  3EWQ A;  5D8N A;  3EWP A;  3GPO A;  4ETJ A;  3SII A;  2VRI A;  2W2G A;  5E3B A;  4ETK A;  3KQX A;  3ETI A;  3JRU A;  3EWO A;  4JGK A;  4ESS A;  1LAP A;  3EWR A;  4JCA A;  4K3N A;  1TY8 A;  4R6T A;  2FXK A;  4GVW A;  1VHU A;  3GPG A;  4JVV A;  3KR5 A;  4ZX9 A;  3JZT A;  4J4Z A;  1HJZ A;  3IID A;  3SIG A;  5AIL A;  1TXZ A;  4R7M A;  3IIF A;  2EEE A;  4GUA A;  5FSU A;  3H8G A;  3EJG A;  5CMS A;  2DX6 A;  2ACF A;  4ZY0 A;  4J5Q A;  2J9A A;  3Q6Z A;  1ZR5 A;  4GVV A;  2LGR A;  3VFQ A;  2X47 A;  4IQY A;  5HOL A;  5FSX A;  5FSZ A;  4ZYQ A;  2AFC A;  1LCP A;  3SIJ A;  3V45 A;  4R76 A;  1BPN A;  1BLL E;  3GQO A;  4D86 A;  3H8F A;  1LAM A;  4K0C A;  5CB3 A;  3T8W A;  1GYT A;  2FAV A;  2RNK A;  1ZR3 A;  2BFQ A;  4ABL A;  3Q71 A;  4ABK A;  5DUS A;  3EKE A; 
#chains in the Genus database with same CATH homology
 3V2B A;  3EW5 A;  1SPV A;  4ZX8 A;  5CBM A;  4ZY1 A;  2FG1 A;  4JLL A;  4ZI6 A;  3H8E A;  5HIH A;  2BFR A;  4UML A;  3SIH A;  5CB5 A;  1LAN A;  3KZW A;  4KYB A;  3PEI A;  1BPM A;  3EJF A;  3KR4 A;  3IJ3 A;  4J5R A;  3KQZ A;  5FSV A;  5FSY A;  4X2T A;  4TU0 A;  2EWB A;  4KSI A;  4ZY2 A;  2XD7 A;  3GPQ A;  1NJR A;  3GQE A;  1YD9 A;  2L8R A;  4J5S A;  3EWQ A;  5D8N A;  3EWP A;  3GPO A;  4ETJ A;  3SII A;  2VRI A;  5E3B A;  4ETK A;  3ETI A;  3JRU A;  3KQX A;  4JGK A;  3EWO A;  4ESS A;  1LAP A;  3EWR A;  4JCA A;  4K3N A;  1TY8 A;  4R6T A;  2FXK A;  4GVW A;  1VHU A;  3GPG A;  4JVV A;  3KR5 A;  4ZX9 A;  3JZT A;  4J4Z A;  1HJZ A;  3IID A;  3SIG A;  5AIL A;  1TXZ A;  4R7M A;  3IIF A;  2EEE A;  4GUA A;  5FSU A;  3H8G A;  3EJG A;  5CMS A;  2DX6 A;  2ACF A;  4ZY0 A;  4J5Q A;  2J9A A;  3Q6Z A;  1ZR5 A;  4GVV A;  2LGR A;  3VFQ A;  2X47 A;  4IQY A;  5HOL A;  5FSX A;  5FSZ A;  4ZYQ A;  2AFC A;  1LCP A;  3SIJ A;  3V45 A;  4R76 A;  1BPN A;  1BLL E;  3GQO A;  4D86 A;  3H8F A;  1LAM A;  4K0C A;  5CB3 A;  3T8W A;  1GYT A;  2FAV A;  1ZR3 A;  2BFQ A;  4ABL A;  3Q71 A;  4ABK A;  5DUS A;  3EKE A; 
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similar chains in the Genus database (?% sequence similarity)
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