5HIHA

Crystal structure of the macro domain in middle-east respiratory syndrome coronavirus
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
167
structure length
167
Chain Sequence
MDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
pubmed doi rcsb
molecule tags Viral protein
source organism Middle east respiratory syndrome coronavirus
molecule keywords ORF1a
total genus 57
structure length 167
sequence length 167
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2016-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5hihA00
4D86A 5HIHA 3JRUA 5CB5A 3PEIA 3EWRA 2FXKA 3EWQA 4IQYA 3EJGA 4K3NA 4JGKA 4JCAA 4GVWA 5CBMA 5D8NA 5FSZA 1BPNA 4ZY2A 3KR5A 4ESSA 3SIIA 3GPGA 2VRIA 3JZTA 2EWBA 1SPVA 3EWPA 4GUAA 2AFCA 4ABKA 3KR4A 4ZI6A 4J5QA 5FSYA 4ETKA 4TU0A 1LAPA 1BLLE 2FG1A 3GQOA 3GPQA 3KZWA 3EWOA 1TY8A 2L8RA 5DUSA 4R76A 1HJZA 1YD9A 1GYTA 2BFRA 3H8FA 5FSXA 4KYBA 5FSVA 3H8GA 3VFQA 4ZX8A 2X47A 4ZY0A 3EW5A 3V45A 3GPOA 4GVVA 3SIHA 2FAVA 2ACFA 5FSUA 5HOLA 4ABLA 3IIDA 2J9AA 3KQZA 3GQEA 4R7MA 4J4ZA 1LAMA 1LANA 3IIFA 1VHUA 4J5SA 4R6TA 5AILA 3V2BA 3Q71A 2XD7A 1TXZA 1ZR5A 4ZY1A 2EEEA 5E3BA 1LCPA 4JLLA 4K0CA 3ETIA 5CMSA 3SIGA 4KSIA 1NJRA 3H8EA 4ETJA 5CB3A 4JVVA 4J5RA 4UMLA 4ZYQA 3T8WA 2BFQA 2DX6A 1ZR3A 3IJ3A 1BPMA 4X2TA 3SIJA 2LGRA 4ZX9A 3KQXA 3EKEA 3Q6ZA 3EJFA
chains in the Genus database with same CATH superfamily
4D86A 2JZFA 5HIHA 3JRUA 5CB5A 3PEIA 3EWRA 2FXKA 3EWQA 4IQYA 3EJGA 4K3NA 4JGKA 4JCAA 4GVWA 5CBMA 5D8NA 5FSZA 1BPNA 4ZY2A 3KR5A 4ESSA 3SIIA 3GPGA 2VRIA 3JZTA 2EWBA 1SPVA 3EWPA 4GUAA 2AFCA 4ABKA 3KR4A 4ZI6A 2JZDA 4J5QA 5FSYA 4ETKA 4TU0A 1LAPA 1BLLE 2FG1A 3GQOA 3GPQA 3KZWA 3EWOA 1TY8A 2L8RA 5DUSA 4R76A 1HJZA 1YD9A 1GYTA 2BFRA 2WCTA 3H8FA 5FSXA 4KYBA 5FSVA 3H8GA 3VFQA 4ZX8A 2X47A 4ZY0A 3EW5A 2RNKA 3V45A 3GPOA 2W2GA 4GVVA 3SIHA 2FAVA 2ACFA 5FSUA 5HOLA 4ABLA 3IIDA 2J9AA 3KQZA 3GQEA 4R7MA 4J4ZA 1LAMA 1LANA 3IIFA 1VHUA 4J5SA 4R6TA 5AILA 3V2BA 3Q71A 2XD7A 1TXZA 1ZR5A 4ZY1A 2EEEA 5E3BA 1LCPA 4JLLA 4K0CA 3ETIA 5CMSA 3SIGA 4KSIA 1NJRA 3H8EA 4ETJA 2JZEA 2KQVA 5CB3A 4JVVA 4J5RA 4UMLA 4ZYQA 3T8WA 2BFQA 2DX6A 1ZR3A 3IJ3A 1BPMA 4X2TA 3SIJA 2LGRA 4ZX9A 3KQXA 3EKEA 3Q6ZA 3EJFA
chains in the Genus database with same CATH topology
4D86A 5HIHA 3JRUA 5CB5A 3PEIA 3EWRA 2FXKA 3EWQA 4IQYA 3EJGA 4K3NA 4JGKA 4JCAA 4GVWA 5CBMA 5D8NA 5FSZA 1BPNA 4ZY2A 3KR5A 4ESSA 3SIIA 3GPGA 2VRIA 3JZTA 2EWBA 1SPVA 3EWPA 4GUAA 2AFCA 4ABKA 3KR4A 4ZI6A 4J5QA 5FSYA 4ETKA 4TU0A 1LAPA 1BLLE 2FG1A 3GQOA 3GPQA 3KZWA 3EWOA 1TY8A 2L8RA 5DUSA 4R76A 1HJZA 1YD9A 1GYTA 2BFRA 3H8FA 5FSXA 4KYBA 5FSVA 3H8GA 3VFQA 4ZX8A 2X47A 4ZY0A 3EW5A 3V45A 3GPOA 4GVVA 3SIHA 2FAVA 2ACFA 5FSUA 5HOLA 4ABLA 3IIDA 2J9AA 3KQZA 3GQEA 4R7MA 4J4ZA 1LAMA 1LANA 3IIFA 1VHUA 4J5SA 4R6TA 5AILA 3V2BA 3Q71A 2XD7A 1TXZA 1ZR5A 4ZY1A 2EEEA 5E3BA 1LCPA 4JLLA 4K0CA 3ETIA 5CMSA 3SIGA 4KSIA 1NJRA 3H8EA 4ETJA 5CB3A 4JVVA 4J5RA 4UMLA 4ZYQA 3T8WA 2BFQA 2DX6A 1ZR3A 3IJ3A 1BPMA 4X2TA 3SIJA 2LGRA 4ZX9A 3KQXA 3EKEA 3Q6ZA 3EJFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D86 A;  5HIH A;  3JRU A;  5CB5 A;  3PEI A;  3EWR A;  2FXK A;  3EWQ A;  4IQY A;  3EJG A;  4K3N A;  4JGK A;  4JCA A;  4GVW A;  5CBM A;  5D8N A;  5FSZ A;  1BPN A;  4ZY2 A;  3KR5 A;  4ESS A;  3SII A;  3GPG A;  2VRI A;  3JZT A;  2EWB A;  1SPV A;  3EWP A;  4GUA A;  2AFC A;  4ABK A;  3KR4 A;  4ZI6 A;  4J5Q A;  5FSY A;  4ETK A;  4TU0 A;  1LAP A;  1BLL E;  2FG1 A;  3GQO A;  3GPQ A;  3KZW A;  3EWO A;  1TY8 A;  2L8R A;  5DUS A;  4R76 A;  1HJZ A;  1YD9 A;  1GYT A;  2BFR A;  3H8F A;  5FSX A;  4KYB A;  5FSV A;  3H8G A;  3VFQ A;  4ZX8 A;  2X47 A;  4ZY0 A;  3EW5 A;  3V45 A;  3GPO A;  4GVV A;  3SIH A;  2FAV A;  2ACF A;  5FSU A;  5HOL A;  4ABL A;  3IID A;  2J9A A;  3KQZ A;  3GQE A;  4R7M A;  4J4Z A;  1LAM A;  1LAN A;  3IIF A;  1VHU A;  4J5S A;  4R6T A;  5AIL A;  3V2B A;  3Q71 A;  2XD7 A;  1TXZ A;  1ZR5 A;  4ZY1 A;  2EEE A;  5E3B A;  1LCP A;  4JLL A;  4K0C A;  3ETI A;  5CMS A;  3SIG A;  4KSI A;  1NJR A;  3H8E A;  4ETJ A;  5CB3 A;  4JVV A;  4J5R A;  4UML A;  4ZYQ A;  3T8W A;  2BFQ A;  2DX6 A;  1ZR3 A;  3IJ3 A;  1BPM A;  4X2T A;  3SIJ A;  2LGR A;  4ZX9 A;  3KQX A;  3EKE A;  3Q6Z A;  3EJF A; 
#chains in the Genus database with same CATH topology
 4D86 A;  2JZF A;  5HIH A;  3JRU A;  5CB5 A;  3PEI A;  3EWR A;  2FXK A;  3EWQ A;  4IQY A;  3EJG A;  4K3N A;  4JGK A;  4JCA A;  4GVW A;  5CBM A;  5D8N A;  5FSZ A;  1BPN A;  4ZY2 A;  3KR5 A;  4ESS A;  3SII A;  3GPG A;  2VRI A;  3JZT A;  2EWB A;  1SPV A;  3EWP A;  4GUA A;  2AFC A;  4ABK A;  3KR4 A;  4ZI6 A;  2JZD A;  4J5Q A;  5FSY A;  4ETK A;  4TU0 A;  1LAP A;  1BLL E;  2FG1 A;  3GQO A;  3GPQ A;  3KZW A;  3EWO A;  1TY8 A;  2L8R A;  5DUS A;  4R76 A;  1HJZ A;  1YD9 A;  1GYT A;  2BFR A;  2WCT A;  3H8F A;  5FSX A;  4KYB A;  5FSV A;  3H8G A;  3VFQ A;  4ZX8 A;  2X47 A;  4ZY0 A;  3EW5 A;  2RNK A;  3V45 A;  3GPO A;  2W2G A;  4GVV A;  3SIH A;  2FAV A;  2ACF A;  5FSU A;  5HOL A;  4ABL A;  3IID A;  2J9A A;  3KQZ A;  3GQE A;  4R7M A;  4J4Z A;  1LAM A;  1LAN A;  3IIF A;  1VHU A;  4J5S A;  4R6T A;  5AIL A;  3V2B A;  3Q71 A;  2XD7 A;  1TXZ A;  1ZR5 A;  4ZY1 A;  2EEE A;  5E3B A;  1LCP A;  4JLL A;  4K0C A;  3ETI A;  5CMS A;  3SIG A;  4KSI A;  1NJR A;  3H8E A;  4ETJ A;  2JZE A;  2KQV A;  5CB3 A;  4JVV A;  4J5R A;  4UML A;  4ZYQ A;  3T8W A;  2BFQ A;  2DX6 A;  1ZR3 A;  3IJ3 A;  1BPM A;  4X2T A;  3SIJ A;  2LGR A;  4ZX9 A;  3KQX A;  3EKE A;  3Q6Z A;  3EJF A; 
#chains in the Genus database with same CATH homology
 4D86 A;  5HIH A;  3JRU A;  5CB5 A;  3PEI A;  3EWR A;  2FXK A;  3EWQ A;  4IQY A;  3EJG A;  4K3N A;  4JGK A;  4JCA A;  4GVW A;  5CBM A;  5D8N A;  5FSZ A;  1BPN A;  4ZY2 A;  3KR5 A;  4ESS A;  3SII A;  3GPG A;  2VRI A;  3JZT A;  2EWB A;  1SPV A;  3EWP A;  4GUA A;  2AFC A;  4ABK A;  3KR4 A;  4ZI6 A;  4J5Q A;  5FSY A;  4ETK A;  4TU0 A;  1LAP A;  1BLL E;  2FG1 A;  3GQO A;  3GPQ A;  3KZW A;  3EWO A;  1TY8 A;  2L8R A;  5DUS A;  4R76 A;  1HJZ A;  1YD9 A;  1GYT A;  2BFR A;  3H8F A;  5FSX A;  4KYB A;  5FSV A;  3H8G A;  3VFQ A;  4ZX8 A;  2X47 A;  4ZY0 A;  3EW5 A;  3V45 A;  3GPO A;  4GVV A;  3SIH A;  2FAV A;  2ACF A;  5FSU A;  5HOL A;  4ABL A;  3IID A;  2J9A A;  3KQZ A;  3GQE A;  4R7M A;  4J4Z A;  1LAM A;  1LAN A;  3IIF A;  1VHU A;  4J5S A;  4R6T A;  5AIL A;  3V2B A;  3Q71 A;  2XD7 A;  1TXZ A;  1ZR5 A;  4ZY1 A;  2EEE A;  5E3B A;  1LCP A;  4JLL A;  4K0C A;  3ETI A;  5CMS A;  3SIG A;  4KSI A;  1NJR A;  3H8E A;  4ETJ A;  5CB3 A;  4JVV A;  4J5R A;  4UML A;  4ZYQ A;  3T8W A;  2BFQ A;  2DX6 A;  1ZR3 A;  3IJ3 A;  1BPM A;  4X2T A;  3SIJ A;  2LGR A;  4ZX9 A;  3KQX A;  3EKE A;  3Q6Z A;  3EJF A; 
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similar chains in the Genus database (?% sequence similarity)
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