1P9PA

The crystal structure of a m1g37 trna methyltransferase, trmd
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
Knots found
sequence length
246
structure length
235
Chain Sequence
MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Escherichia coli
publication title Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
pubmed doi rcsb
molecule keywords tRNA (Guanine-N(1)-)-methyltransferase
total genus 67
structure length 235
sequence length 246
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2003-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 1p9pA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1p9pA01
4YQGA 4CNGA 3DCMX 4YQTA 4PZKA 1V2XA 4YQKA 1K3RA 4YPWA 3OIIA 4YQSA 4YQJA 4KGNA 1VHKA 4YQ6A 5GM8A 2I6DA 4JALA 4YPXA 1P9PA 4L69A 1VHYA 4YQOA 4YVIA 1TO0A 3BBDA 3OINA 3BBHA 3AI9X 4CNEA 4E8BA 4YVJA 1IPAA 4XBOA 1X7PA 4YQPA 3N4JA 3L8UA 5FAIA 5GMCA 2CX8A 4H3ZA 4YQ5A 4YQ9A 4YQ1A 3KW2A 1VH0A 2YY8A 5CO4A 4FAKA 2V3KA 3QUVA 4RG1A 2QWVA 2V3JA 1X7OA 1ZJRA 4YQ0A 3E5YA 4YVGA 4YQRA 5D9FA 4J3CA 3ONPA 4YQQA 4X3MA 3NK6A 2Z0YA 4YQ2A 4YQ4A 4MCBA 4YPYA 4YQIA 1OY5A 4KDZA 3GYQA 1MXIA 1UALA 4IG6A 4MCCA 4YQNA 1O6DA 1Z85A 4YQ8A 5GMBA 3N4KA 4YQDA 3KTYA 4JAKA 3BBEA 2EGWA 4YPZA 1GZ0A 2O3AA 3O7BA 3OIJA 3AXZA 1J85A 2EGVA 4YQAA 3NK7A 4YQBA 4MCDA 4YVKA 3IEFA 4CNFA 3KNUA 3ILKA 4H3YA 4YVHA 4YQLA 3IC6A 1V6ZA 2HA8A 3AIAA 4YQCA 1UAJA 4CNDA 1NXZA 4YQ7A 1UAKA 2QMMA 4X3LA 1UAMA 4YQ3A 3KY7A 1NS5A
chains in the Genus database with same CATH superfamily
4YQGA 4CNGA 3DCMX 4YQTA 4PZKA 1V2XA 4YQKA 1CO0A 3SSWN 1K3RA 4YPWA 3OIIA 4YQSA 4YQJA 4KGNA 1VHKA 4YQ6A 5GM8A 2I6DA 4JALA 4YPXA 3WRPA 1P9PA 2XDIA 1JHGA 3SSXN 4L69A 4JWHA 1VHYA 4YQOA 2OZ9R 4YVIA 1TO0A 3BBDA 3OINA 3BBHA 4JWGA 3AI9X 4CNEA 4E8BA 4YVJA 1IPAA 4XBOA 1X7PA 4YQPA 3N4JA 3L8UA 5FAIA 5GMCA 2CX8A 4H3ZA 4YQ5A 3KORA 4YQ9A 4YQ1A 3KW2A 1VH0A 2YY8A 5CO4A 4FAKA 2V3KA 3QUVA 4RG1A 2QWVA 2V3JA 4JWFA 1X7OA 1WRPR 1ZJRA 4YQ0A 3E5YA 4YVGA 4YQRA 5D9FA 3G1CA 1TRRA 4YQQA 3ONPA 4J3CA 4X3MA 3NK6A 2Z0YA 4YQ2A 1WRTR 4YQ4A 4MCBA 4YPYA 4YQIA 1OY5A 4KDZA 3GYQA 1MXIA 1UALA 1MI7R 4IG6A 4MCCA 4YQNA 1TROA 4YQ8A 1O6DA 1Z85A 3N4KA 5GMBA 4YQDA 4JWJA 3KTYA 4JAKA 3BBEA 2EGWA 4YPZA 1GZ0A 2O3AA 3O7BA 3OIJA 1WRSR 3AXZA 1J85A 2EGVA 3FRWA 4YQAA 3NK7A 4YQBA 4MCDA 1ZT9A 4YVKA 3IEFA 4CNFA 3KNUA 3ILKA 4H3YA 4YVHA 4YQLA 3IC6A 1V6ZA 2HA8A 3AIAA 4YQCA 1RCSA 1UAJA 4CNDA 4FMWA 1NXZA 4YQ7A 1UAKA 2QMMA 4X3LA 1UAMA 4YQ3A 3KY7A 1NS5A
chains in the Genus database with same CATH topology
4YQGA 4CNGA 3DCMX 4YQTA 4PZKA 1V2XA 4YQKA 1K3RA 4YPWA 3OIIA 4YQSA 4YQJA 4KGNA 1VHKA 4YQ6A 5GM8A 2I6DA 4JALA 4YPXA 1P9PA 4L69A 4JWHA 1VHYA 4YQOA 4YVIA 1TO0A 3BBDA 3OINA 3BBHA 4JWGA 3AI9X 4CNEA 4E8BA 4YVJA 1IPAA 4XBOA 1X7PA 4YQPA 3N4JA 3L8UA 5FAIA 5GMCA 2CX8A 4H3ZA 4YQ5A 4YQ9A 4YQ1A 3KW2A 1VH0A 2YY8A 5CO4A 4FAKA 2V3KA 3QUVA 4RG1A 2QWVA 2V3JA 4JWFA 1X7OA 1ZJRA 4YQ0A 3E5YA 4YVGA 4YQRA 5D9FA 4J3CA 3ONPA 4YQQA 4X3MA 3NK6A 2Z0YA 4YQ2A 4YQ4A 4MCBA 4YPYA 4YQIA 1OY5A 4KDZA 3GYQA 1MXIA 1UALA 4IG6A 4MCCA 4YQNA 1O6DA 1Z85A 4YQ8A 5GMBA 3N4KA 4YQDA 4JWJA 3KTYA 4JAKA 3BBEA 2EGWA 4YPZA 1GZ0A 2O3AA 3O7BA 3OIJA 3AXZA 1J85A 2EGVA 4YQAA 3NK7A 4YQBA 4MCDA 4YVKA 3IEFA 4CNFA 3KNUA 3ILKA 4H3YA 4YVHA 4YQLA 3IC6A 1V6ZA 2HA8A 3AIAA 4YQCA 1UAJA 4CNDA 4FMWA 1NXZA 4YQ7A 1UAKA 2QMMA 4X3LA 1UAMA 4YQ3A 3KY7A 1NS5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQG A;  4CNG A;  3DCM X;  4YQT A;  4PZK A;  1V2X A;  4YQK A;  1K3R A;  4YPW A;  3OII A;  4YQS A;  4YQJ A;  4KGN A;  1VHK A;  4YQ6 A;  5GM8 A;  2I6D A;  4JAL A;  4YPX A;  1P9P A;  4L69 A;  1VHY A;  4YQO A;  4YVI A;  1TO0 A;  3BBD A;  3OIN A;  3BBH A;  3AI9 X;  4CNE A;  4E8B A;  4YVJ A;  1IPA A;  4XBO A;  1X7P A;  4YQP A;  3N4J A;  3L8U A;  5FAI A;  5GMC A;  2CX8 A;  4H3Z A;  4YQ5 A;  4YQ9 A;  4YQ1 A;  3KW2 A;  1VH0 A;  2YY8 A;  5CO4 A;  4FAK A;  2V3K A;  3QUV A;  4RG1 A;  2QWV A;  2V3J A;  1X7O A;  1ZJR A;  4YQ0 A;  3E5Y A;  4YVG A;  4YQR A;  5D9F A;  4J3C A;  3ONP A;  4YQQ A;  4X3M A;  3NK6 A;  2Z0Y A;  4YQ2 A;  4YQ4 A;  4MCB A;  4YPY A;  4YQI A;  1OY5 A;  4KDZ A;  3GYQ A;  1MXI A;  1UAL A;  4IG6 A;  4MCC A;  4YQN A;  1O6D A;  1Z85 A;  4YQ8 A;  5GMB A;  3N4K A;  4YQD A;  3KTY A;  4JAK A;  3BBE A;  2EGW A;  4YPZ A;  1GZ0 A;  2O3A A;  3O7B A;  3OIJ A;  3AXZ A;  1J85 A;  2EGV A;  4YQA A;  3NK7 A;  4YQB A;  4MCD A;  4YVK A;  3IEF A;  4CNF A;  3KNU A;  3ILK A;  4H3Y A;  4YVH A;  4YQL A;  3IC6 A;  1V6Z A;  2HA8 A;  3AIA A;  4YQC A;  1UAJ A;  4CND A;  1NXZ A;  4YQ7 A;  1UAK A;  2QMM A;  4X3L A;  1UAM A;  4YQ3 A;  3KY7 A;  1NS5 A; 
#chains in the Genus database with same CATH topology
 4YQG A;  4CNG A;  3DCM X;  4YQT A;  4PZK A;  1V2X A;  4YQK A;  1CO0 A;  3SSW N;  1K3R A;  4YPW A;  3OII A;  4YQS A;  4YQJ A;  4KGN A;  1VHK A;  4YQ6 A;  5GM8 A;  2I6D A;  4JAL A;  4YPX A;  3WRP A;  1P9P A;  2XDI A;  1JHG A;  3SSX N;  4L69 A;  4JWH A;  1VHY A;  4YQO A;  2OZ9 R;  4YVI A;  1TO0 A;  3BBD A;  3OIN A;  3BBH A;  4JWG A;  3AI9 X;  4CNE A;  4E8B A;  4YVJ A;  1IPA A;  4XBO A;  1X7P A;  4YQP A;  3N4J A;  3L8U A;  5FAI A;  5GMC A;  2CX8 A;  4H3Z A;  4YQ5 A;  3KOR A;  4YQ9 A;  4YQ1 A;  3KW2 A;  1VH0 A;  2YY8 A;  5CO4 A;  4FAK A;  2V3K A;  3QUV A;  4RG1 A;  2QWV A;  2V3J A;  4JWF A;  1X7O A;  1WRP R;  1ZJR A;  4YQ0 A;  3E5Y A;  4YVG A;  4YQR A;  5D9F A;  3G1C A;  1TRR A;  4YQQ A;  3ONP A;  4J3C A;  4X3M A;  3NK6 A;  2Z0Y A;  4YQ2 A;  1WRT R;  4YQ4 A;  4MCB A;  4YPY A;  4YQI A;  1OY5 A;  4KDZ A;  3GYQ A;  1MXI A;  1UAL A;  1MI7 R;  4IG6 A;  4MCC A;  4YQN A;  1TRO A;  4YQ8 A;  1O6D A;  1Z85 A;  3N4K A;  5GMB A;  4YQD A;  4JWJ A;  3KTY A;  4JAK A;  3BBE A;  2EGW A;  4YPZ A;  1GZ0 A;  2O3A A;  3O7B A;  3OIJ A;  1WRS R;  3AXZ A;  1J85 A;  2EGV A;  3FRW A;  4YQA A;  3NK7 A;  4YQB A;  4MCD A;  1ZT9 A;  4YVK A;  3IEF A;  4CNF A;  3KNU A;  3ILK A;  4H3Y A;  4YVH A;  4YQL A;  3IC6 A;  1V6Z A;  2HA8 A;  3AIA A;  4YQC A;  1RCS A;  1UAJ A;  4CND A;  4FMW A;  1NXZ A;  4YQ7 A;  1UAK A;  2QMM A;  4X3L A;  1UAM A;  4YQ3 A;  3KY7 A;  1NS5 A; 
#chains in the Genus database with same CATH homology
 4YQG A;  4CNG A;  3DCM X;  4YQT A;  4PZK A;  1V2X A;  4YQK A;  1K3R A;  4YPW A;  3OII A;  4YQS A;  4YQJ A;  4KGN A;  1VHK A;  4YQ6 A;  5GM8 A;  2I6D A;  4JAL A;  4YPX A;  1P9P A;  4L69 A;  4JWH A;  1VHY A;  4YQO A;  4YVI A;  1TO0 A;  3BBD A;  3OIN A;  3BBH A;  4JWG A;  3AI9 X;  4CNE A;  4E8B A;  4YVJ A;  1IPA A;  4XBO A;  1X7P A;  4YQP A;  3N4J A;  3L8U A;  5FAI A;  5GMC A;  2CX8 A;  4H3Z A;  4YQ5 A;  4YQ9 A;  4YQ1 A;  3KW2 A;  1VH0 A;  2YY8 A;  5CO4 A;  4FAK A;  2V3K A;  3QUV A;  4RG1 A;  2QWV A;  2V3J A;  4JWF A;  1X7O A;  1ZJR A;  4YQ0 A;  3E5Y A;  4YVG A;  4YQR A;  5D9F A;  4J3C A;  3ONP A;  4YQQ A;  4X3M A;  3NK6 A;  2Z0Y A;  4YQ2 A;  4YQ4 A;  4MCB A;  4YPY A;  4YQI A;  1OY5 A;  4KDZ A;  3GYQ A;  1MXI A;  1UAL A;  4IG6 A;  4MCC A;  4YQN A;  1O6D A;  1Z85 A;  4YQ8 A;  5GMB A;  3N4K A;  4YQD A;  4JWJ A;  3KTY A;  4JAK A;  3BBE A;  2EGW A;  4YPZ A;  1GZ0 A;  2O3A A;  3O7B A;  3OIJ A;  3AXZ A;  1J85 A;  2EGV A;  4YQA A;  3NK7 A;  4YQB A;  4MCD A;  4YVK A;  3IEF A;  4CNF A;  3KNU A;  3ILK A;  4H3Y A;  4YVH A;  4YQL A;  3IC6 A;  1V6Z A;  2HA8 A;  3AIA A;  4YQC A;  1UAJ A;  4CND A;  4FMW A;  1NXZ A;  4YQ7 A;  1UAK A;  2QMM A;  4X3L A;  1UAM A;  4YQ3 A;  3KY7 A;  1NS5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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