4H3YA

Crystal structure of an asymmetric dimer of a trna (guanine-(n(1)-)-methyltransferase from burkholderia phymatum bound to s-adenosyl homocystein in one half-site
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
Knots found
sequence length
255
structure length
255
Chain Sequence
SMQFDIVTLFPDMFRALTDWGITSRAAKQERYGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLARPLEDAINAAKAAQAEQGIGGARVVMMSPQGATLNHDKVMRFAAEPGLILLCGRYEAIDQRLIDRVVDEEVSLGDFVLSGGELPAMALIDAVVRHLPGVLNDAQSAVQDSFVDGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEQWRRREALRNTWLKRPDLIVQARKNKLLSRADEAWLASLAKDASK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Combining functional and structural genomics to sample the essential Burkholderia structome.
pubmed doi rcsb
molecule tags Transferase
source organism Burkholderia phymatum
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 77
structure length 255
sequence length 255
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4h3yA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4h3yA01
2QWVA 5D9FA 1O6DA 2I6DA 2V3KA 4CNGA 4E8BA 4IG6A 4YQTA 3O7BA 4YQ1A 1ZJRA 3ILKA 4YPXA 4X3MA 3AI9X 4PZKA 2YY8A 3BBEA 4YQ6A 5GMBA 4YQCA 4FAKA 4MCCA 4YQRA 3E5YA 4YQIA 4YQLA 3KNUA 4YQGA 4RG1A 4CNFA 1UALA 4YQ4A 3QUVA 4JAKA 4YQSA 3NK7A 4YVJA 4YQAA 3KTYA 3BBHA 3DCMX 1TO0A 2O3AA 2HA8A 5GMCA 3N4KA 2V3JA 4H3YA 4YVGA 4YQKA 4H3ZA 2CX8A 1V2XA 1V6ZA 1X7OA 3KY7A 4YQ0A 4YQ5A 1J85A 1VH0A 4JALA 1MXIA 5FAIA 4YPWA 4YQBA 2EGVA 4YQJA 3AXZA 5CO4A 3IC6A 5GM8A 4KGNA 1UAMA 1P9PA 4L69A 4YQ9A 1X7PA 3N4JA 1VHYA 2Z0YA 3OINA 4YVIA 2QMMA 4CNEA 2EGWA 4YPZA 1OY5A 4YQQA 4XBOA 4YQDA 1UAKA 3OIIA 4YQ3A 3KW2A 4KDZA 3OIJA 3GYQA 4YQ7A 3ONPA 4YVKA 3BBDA 3NK6A 3IEFA 1GZ0A 4X3LA 4YQ8A 4YQPA 1NS5A 1UAJA 4YQOA 1VHKA 3L8UA 1NXZA 4CNDA 1IPAA 4YPYA 4MCBA 1K3RA 3AIAA 4YQNA 4MCDA 4J3CA 4YQ2A 1Z85A 4YVHA
chains in the Genus database with same CATH superfamily
2QWVA 5D9FA 1O6DA 1ZT9A 2I6DA 2V3KA 1MI7R 4CNGA 4E8BA 4IG6A 4YQTA 3FRWA 4YQ1A 3O7BA 1ZJRA 3ILKA 4YPXA 4X3MA 3AI9X 4PZKA 2YY8A 3BBEA 4YQ6A 5GMBA 4YQCA 4FAKA 4MCCA 3SSWN 4YQRA 3E5YA 4YQIA 4YQLA 3KNUA 4YQGA 4RG1A 4CNFA 1UALA 4YQ4A 3QUVA 4JAKA 4YQSA 3NK7A 4YVJA 4YQAA 3KTYA 3BBHA 3DCMX 1TO0A 2O3AA 2HA8A 4JWJA 5GMCA 3N4KA 4JWFA 2V3JA 4H3YA 4YVGA 4YQKA 3G1CA 4H3ZA 2CX8A 1V2XA 1V6ZA 1X7OA 3KY7A 4YQ0A 2XDIA 4YQ5A 1J85A 1VH0A 4JALA 1MXIA 5FAIA 4YPWA 4YQBA 2EGVA 4YQJA 3AXZA 5CO4A 1TROA 3IC6A 5GM8A 4KGNA 1UAMA 1P9PA 4L69A 4YQ9A 1X7PA 1WRSR 3N4JA 1VHYA 2Z0YA 3OINA 4YVIA 1RCSA 2QMMA 4CNEA 1Z85A 1WRTR 2EGWA 4YPZA 1OY5A 4YQQA 4XBOA 4YQDA 1UAKA 1WRPR 2OZ9R 3OIIA 4YQ3A 3KORA 3KW2A 4KDZA 3OIJA 4JWGA 3GYQA 4YQ7A 3ONPA 4YVKA 3BBDA 4JWHA 1CO0A 3WRPA 3NK6A 3IEFA 1GZ0A 4X3LA 4YQ8A 4YQPA 1NS5A 1UAJA 4YQOA 1VHKA 3L8UA 4FMWA 1NXZA 4CNDA 1IPAA 3SSXN 4YPYA 4MCBA 1K3RA 1TRRA 3AIAA 4YQNA 4MCDA 4J3CA 4YQ2A 1JHGA 4YVHA
chains in the Genus database with same CATH topology
2QWVA 5D9FA 1O6DA 2I6DA 2V3KA 4CNGA 4E8BA 4IG6A 4YQTA 3O7BA 4YQ1A 1ZJRA 3ILKA 4YPXA 4X3MA 3AI9X 4PZKA 2YY8A 3BBEA 4YQ6A 5GMBA 4YQCA 4FAKA 4MCCA 4YQRA 3E5YA 4YQIA 4YQLA 3KNUA 4YQGA 4RG1A 4CNFA 1UALA 4YQ4A 3QUVA 4JAKA 4YQSA 3NK7A 4YVJA 4YQAA 3KTYA 3BBHA 3DCMX 1TO0A 2O3AA 2HA8A 4JWJA 5GMCA 3N4KA 4JWFA 2V3JA 4H3YA 4YVGA 4YQKA 4H3ZA 2CX8A 1V2XA 1V6ZA 1X7OA 3KY7A 4YQ0A 4YQ5A 1J85A 1VH0A 4JALA 1MXIA 5FAIA 4YPWA 4YQBA 2EGVA 4YQJA 3AXZA 5CO4A 3IC6A 5GM8A 4KGNA 1UAMA 1P9PA 4L69A 4YQ9A 1X7PA 3N4JA 1VHYA 2Z0YA 3OINA 4YVIA 2QMMA 4CNEA 2EGWA 4YPZA 1OY5A 4YQQA 4XBOA 4YQDA 1UAKA 3OIIA 4YQ3A 3KW2A 4KDZA 3OIJA 4JWGA 3GYQA 4YQ7A 3ONPA 4YVKA 3BBDA 4JWHA 3NK6A 3IEFA 1GZ0A 4X3LA 4YQ8A 4YQPA 1NS5A 1UAJA 4YQOA 1VHKA 3L8UA 4FMWA 1NXZA 4CNDA 1IPAA 4YPYA 4MCBA 1K3RA 3AIAA 4YQNA 4MCDA 4J3CA 4YQ2A 1Z85A 4YVHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QWV A;  5D9F A;  1O6D A;  2I6D A;  2V3K A;  4CNG A;  4E8B A;  4IG6 A;  4YQT A;  3O7B A;  4YQ1 A;  1ZJR A;  3ILK A;  4YPX A;  4X3M A;  3AI9 X;  4PZK A;  2YY8 A;  3BBE A;  4YQ6 A;  5GMB A;  4YQC A;  4FAK A;  4MCC A;  4YQR A;  3E5Y A;  4YQI A;  4YQL A;  3KNU A;  4YQG A;  4RG1 A;  4CNF A;  1UAL A;  4YQ4 A;  3QUV A;  4JAK A;  4YQS A;  3NK7 A;  4YVJ A;  4YQA A;  3KTY A;  3BBH A;  3DCM X;  1TO0 A;  2O3A A;  2HA8 A;  5GMC A;  3N4K A;  2V3J A;  4H3Y A;  4YVG A;  4YQK A;  4H3Z A;  2CX8 A;  1V2X A;  1V6Z A;  1X7O A;  3KY7 A;  4YQ0 A;  4YQ5 A;  1J85 A;  1VH0 A;  4JAL A;  1MXI A;  5FAI A;  4YPW A;  4YQB A;  2EGV A;  4YQJ A;  3AXZ A;  5CO4 A;  3IC6 A;  5GM8 A;  4KGN A;  1UAM A;  1P9P A;  4L69 A;  4YQ9 A;  1X7P A;  3N4J A;  1VHY A;  2Z0Y A;  3OIN A;  4YVI A;  2QMM A;  4CNE A;  2EGW A;  4YPZ A;  1OY5 A;  4YQQ A;  4XBO A;  4YQD A;  1UAK A;  3OII A;  4YQ3 A;  3KW2 A;  4KDZ A;  3OIJ A;  3GYQ A;  4YQ7 A;  3ONP A;  4YVK A;  3BBD A;  3NK6 A;  3IEF A;  1GZ0 A;  4X3L A;  4YQ8 A;  4YQP A;  1NS5 A;  1UAJ A;  4YQO A;  1VHK A;  3L8U A;  1NXZ A;  4CND A;  1IPA A;  4YPY A;  4MCB A;  1K3R A;  3AIA A;  4YQN A;  4MCD A;  4J3C A;  4YQ2 A;  1Z85 A;  4YVH A; 
#chains in the Genus database with same CATH topology
 2QWV A;  5D9F A;  1O6D A;  1ZT9 A;  2I6D A;  2V3K A;  1MI7 R;  4CNG A;  4E8B A;  4IG6 A;  4YQT A;  3FRW A;  4YQ1 A;  3O7B A;  1ZJR A;  3ILK A;  4YPX A;  4X3M A;  3AI9 X;  4PZK A;  2YY8 A;  3BBE A;  4YQ6 A;  5GMB A;  4YQC A;  4FAK A;  4MCC A;  3SSW N;  4YQR A;  3E5Y A;  4YQI A;  4YQL A;  3KNU A;  4YQG A;  4RG1 A;  4CNF A;  1UAL A;  4YQ4 A;  3QUV A;  4JAK A;  4YQS A;  3NK7 A;  4YVJ A;  4YQA A;  3KTY A;  3BBH A;  3DCM X;  1TO0 A;  2O3A A;  2HA8 A;  4JWJ A;  5GMC A;  3N4K A;  4JWF A;  2V3J A;  4H3Y A;  4YVG A;  4YQK A;  3G1C A;  4H3Z A;  2CX8 A;  1V2X A;  1V6Z A;  1X7O A;  3KY7 A;  4YQ0 A;  2XDI A;  4YQ5 A;  1J85 A;  1VH0 A;  4JAL A;  1MXI A;  5FAI A;  4YPW A;  4YQB A;  2EGV A;  4YQJ A;  3AXZ A;  5CO4 A;  1TRO A;  3IC6 A;  5GM8 A;  4KGN A;  1UAM A;  1P9P A;  4L69 A;  4YQ9 A;  1X7P A;  1WRS R;  3N4J A;  1VHY A;  2Z0Y A;  3OIN A;  4YVI A;  1RCS A;  2QMM A;  4CNE A;  1Z85 A;  1WRT R;  2EGW A;  4YPZ A;  1OY5 A;  4YQQ A;  4XBO A;  4YQD A;  1UAK A;  1WRP R;  2OZ9 R;  3OII A;  4YQ3 A;  3KOR A;  3KW2 A;  4KDZ A;  3OIJ A;  4JWG A;  3GYQ A;  4YQ7 A;  3ONP A;  4YVK A;  3BBD A;  4JWH A;  1CO0 A;  3WRP A;  3NK6 A;  3IEF A;  1GZ0 A;  4X3L A;  4YQ8 A;  4YQP A;  1NS5 A;  1UAJ A;  4YQO A;  1VHK A;  3L8U A;  4FMW A;  1NXZ A;  4CND A;  1IPA A;  3SSX N;  4YPY A;  4MCB A;  1K3R A;  1TRR A;  3AIA A;  4YQN A;  4MCD A;  4J3C A;  4YQ2 A;  1JHG A;  4YVH A; 
#chains in the Genus database with same CATH homology
 2QWV A;  5D9F A;  1O6D A;  2I6D A;  2V3K A;  4CNG A;  4E8B A;  4IG6 A;  4YQT A;  3O7B A;  4YQ1 A;  1ZJR A;  3ILK A;  4YPX A;  4X3M A;  3AI9 X;  4PZK A;  2YY8 A;  3BBE A;  4YQ6 A;  5GMB A;  4YQC A;  4FAK A;  4MCC A;  4YQR A;  3E5Y A;  4YQI A;  4YQL A;  3KNU A;  4YQG A;  4RG1 A;  4CNF A;  1UAL A;  4YQ4 A;  3QUV A;  4JAK A;  4YQS A;  3NK7 A;  4YVJ A;  4YQA A;  3KTY A;  3BBH A;  3DCM X;  1TO0 A;  2O3A A;  2HA8 A;  4JWJ A;  5GMC A;  3N4K A;  4JWF A;  2V3J A;  4H3Y A;  4YVG A;  4YQK A;  4H3Z A;  2CX8 A;  1V2X A;  1V6Z A;  1X7O A;  3KY7 A;  4YQ0 A;  4YQ5 A;  1J85 A;  1VH0 A;  4JAL A;  1MXI A;  5FAI A;  4YPW A;  4YQB A;  2EGV A;  4YQJ A;  3AXZ A;  5CO4 A;  3IC6 A;  5GM8 A;  4KGN A;  1UAM A;  1P9P A;  4L69 A;  4YQ9 A;  1X7P A;  3N4J A;  1VHY A;  2Z0Y A;  3OIN A;  4YVI A;  2QMM A;  4CNE A;  2EGW A;  4YPZ A;  1OY5 A;  4YQQ A;  4XBO A;  4YQD A;  1UAK A;  3OII A;  4YQ3 A;  3KW2 A;  4KDZ A;  3OIJ A;  4JWG A;  3GYQ A;  4YQ7 A;  3ONP A;  4YVK A;  3BBD A;  4JWH A;  3NK6 A;  3IEF A;  1GZ0 A;  4X3L A;  4YQ8 A;  4YQP A;  1NS5 A;  1UAJ A;  4YQO A;  1VHK A;  3L8U A;  4FMW A;  1NXZ A;  4CND A;  1IPA A;  4YPY A;  4MCB A;  1K3R A;  3AIA A;  4YQN A;  4MCD A;  4J3C A;  4YQ2 A;  1Z85 A;  4YVH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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