4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
223
structure length
223
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
molecule tags Transferase/transferase inhibitor
source organism Anaplasma phagocytophilum
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 66
structure length 223
sequence length 223
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
3KW2A 1OY5A 4PZKA 5GMBA 2V3JA 3BBDA 4YQRA 4MCDA 4MCBA 1UAKA 3ONPA 4YQBA 2EGVA 4CNGA 4YPYA 1NS5A 1X7OA 4CNDA 4H3YA 4YVJA 1Z85A 1J85A 2YY8A 3NK6A 4YQ6A 3ILKA 4YQ0A 3E5YA 3AI9X 1X7PA 4YQQA 1UAMA 3O7BA 3AIAA 4JALA 3KY7A 2I6DA 3GYQA 4X3LA 4YQGA 5GMCA 4YVGA 4CNFA 4XBOA 4IG6A 1TO0A 4YQOA 4YPXA 4YQLA 4YQIA 1VHYA 2QMMA 2Z0YA 4YQNA 1GZ0A 4YQKA 4RG1A 4YQJA 1K3RA 4YPWA 4YQ8A 4CNEA 3AXZA 4YQ5A 1NXZA 3QUVA 4YQ1A 5CO4A 3L8UA 3IC6A 1ZJRA 1VH0A 2HA8A 4YVKA 2O3AA 4YVHA 4KGNA 5FAIA 1IPAA 3OIJA 4YQAA 4YQPA 5D9FA 4KDZA 4YQCA 3KNUA 4FAKA 3DCMX 4YQ2A 3KTYA 3OIIA 3IEFA 2QWVA 2EGWA 2CX8A 4MCCA 3N4KA 4YQDA 1UAJA 4YQ4A 5GM8A 4YQ7A 1UALA 4YQ9A 3N4JA 1P9PA 1MXIA 4YVIA 4X3MA 3OINA 4H3ZA 4YQ3A 4JAKA 4E8BA 4L69A 3BBHA 1V2XA 3NK7A 4J3CA 1V6ZA 4YQTA 1O6DA 4YQSA 4YPZA 3BBEA 1VHKA 2V3KA
chains in the Genus database with same CATH superfamily
3KW2A 1OY5A 4PZKA 5GMBA 2V3JA 3BBDA 4YQRA 4MCDA 4MCBA 1UAKA 3ONPA 4YQBA 3WRPA 2EGVA 4CNGA 4YPYA 1NS5A 1X7OA 4CNDA 4H3YA 4YVJA 1Z85A 1J85A 2YY8A 3NK6A 4YQ6A 3ILKA 4YQ0A 3SSWN 3E5YA 3AI9X 1CO0A 3SSXN 1X7PA 4YQQA 1UAMA 3O7BA 4JWGA 3AIAA 4JALA 3KY7A 2I6DA 3GYQA 4X3LA 4YQGA 5GMCA 4FMWA 1WRSR 4YVGA 4CNFA 4XBOA 4IG6A 1TO0A 4YQOA 2OZ9R 1RCSA 4YPXA 4YQLA 4YQIA 1VHYA 2QMMA 2Z0YA 4JWJA 4YQNA 1GZ0A 4YQKA 4RG1A 4YQJA 1K3RA 4YPWA 4YQ8A 1WRPR 4CNEA 1MI7R 3AXZA 4YQ5A 1NXZA 3QUVA 4JWFA 4YQ1A 3KORA 5CO4A 3L8UA 3IC6A 1ZJRA 1VH0A 2HA8A 4YVKA 2O3AA 4YVHA 2XDIA 4KGNA 1TROA 5FAIA 1IPAA 3OIJA 4YQAA 3G1CA 4YQPA 5D9FA 4KDZA 4YQCA 3KNUA 4FAKA 1JHGA 4YQ2A 3DCMX 3KTYA 3OIIA 3IEFA 2QWVA 2EGWA 2CX8A 4MCCA 3N4KA 4YQDA 1UAJA 4YQ4A 5GM8A 4YQ7A 1UALA 4YQ9A 3N4JA 1P9PA 1MXIA 4YVIA 4X3MA 4JWHA 3OINA 4H3ZA 4YQ3A 4JAKA 4E8BA 4L69A 3BBHA 1V2XA 3NK7A 4J3CA 1WRTR 1V6ZA 1ZT9A 4YQTA 1O6DA 3FRWA 4YQSA 4YPZA 3BBEA 1TRRA 1VHKA 2V3KA
chains in the Genus database with same CATH topology
3KW2A 1OY5A 4PZKA 5GMBA 2V3JA 3BBDA 4YQRA 4MCDA 4MCBA 1UAKA 3ONPA 4YQBA 2EGVA 4CNGA 4YPYA 1NS5A 1X7OA 4CNDA 4H3YA 4YVJA 1Z85A 1J85A 2YY8A 3NK6A 4YQ6A 3ILKA 4YQ0A 3E5YA 3AI9X 1X7PA 4YQQA 1UAMA 3O7BA 4JWGA 3AIAA 4JALA 3KY7A 2I6DA 3GYQA 4X3LA 4YQGA 5GMCA 4FMWA 4YVGA 4CNFA 4XBOA 4IG6A 1TO0A 4YQOA 4YPXA 4YQLA 4YQIA 1VHYA 2QMMA 2Z0YA 4JWJA 4YQNA 1GZ0A 4YQKA 4RG1A 4YQJA 1K3RA 4YPWA 4YQ8A 4CNEA 3AXZA 4YQ5A 1NXZA 3QUVA 4JWFA 4YQ1A 5CO4A 3L8UA 3IC6A 1ZJRA 1VH0A 2HA8A 4YVKA 2O3AA 4YVHA 4KGNA 5FAIA 1IPAA 3OIJA 4YQAA 4YQPA 5D9FA 4KDZA 4YQCA 3KNUA 4FAKA 3DCMX 4YQ2A 3KTYA 3OIIA 3IEFA 2QWVA 2EGWA 2CX8A 4MCCA 3N4KA 4YQDA 1UAJA 4YQ4A 5GM8A 4YQ7A 1UALA 4YQ9A 3N4JA 1P9PA 1MXIA 4YVIA 4X3MA 4JWHA 3OINA 4H3ZA 4YQ3A 4JAKA 4E8BA 4L69A 3BBHA 1V2XA 3NK7A 4J3CA 1V6ZA 4YQTA 1O6DA 4YQSA 4YPZA 3BBEA 1VHKA 2V3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KW2 A;  1OY5 A;  4PZK A;  5GMB A;  2V3J A;  3BBD A;  4YQR A;  4MCD A;  4MCB A;  1UAK A;  3ONP A;  4YQB A;  2EGV A;  4CNG A;  4YPY A;  1NS5 A;  1X7O A;  4CND A;  4H3Y A;  4YVJ A;  1Z85 A;  1J85 A;  2YY8 A;  3NK6 A;  4YQ6 A;  3ILK A;  4YQ0 A;  3E5Y A;  3AI9 X;  1X7P A;  4YQQ A;  1UAM A;  3O7B A;  3AIA A;  4JAL A;  3KY7 A;  2I6D A;  3GYQ A;  4X3L A;  4YQG A;  5GMC A;  4YVG A;  4CNF A;  4XBO A;  4IG6 A;  1TO0 A;  4YQO A;  4YPX A;  4YQL A;  4YQI A;  1VHY A;  2QMM A;  2Z0Y A;  4YQN A;  1GZ0 A;  4YQK A;  4RG1 A;  4YQJ A;  1K3R A;  4YPW A;  4YQ8 A;  4CNE A;  3AXZ A;  4YQ5 A;  1NXZ A;  3QUV A;  4YQ1 A;  5CO4 A;  3L8U A;  3IC6 A;  1ZJR A;  1VH0 A;  2HA8 A;  4YVK A;  2O3A A;  4YVH A;  4KGN A;  5FAI A;  1IPA A;  3OIJ A;  4YQA A;  4YQP A;  5D9F A;  4KDZ A;  4YQC A;  3KNU A;  4FAK A;  3DCM X;  4YQ2 A;  3KTY A;  3OII A;  3IEF A;  2QWV A;  2EGW A;  2CX8 A;  4MCC A;  3N4K A;  4YQD A;  1UAJ A;  4YQ4 A;  5GM8 A;  4YQ7 A;  1UAL A;  4YQ9 A;  3N4J A;  1P9P A;  1MXI A;  4YVI A;  4X3M A;  3OIN A;  4H3Z A;  4YQ3 A;  4JAK A;  4E8B A;  4L69 A;  3BBH A;  1V2X A;  3NK7 A;  4J3C A;  1V6Z A;  4YQT A;  1O6D A;  4YQS A;  4YPZ A;  3BBE A;  1VHK A;  2V3K A; 
#chains in the Genus database with same CATH topology
 3KW2 A;  1OY5 A;  4PZK A;  5GMB A;  2V3J A;  3BBD A;  4YQR A;  4MCD A;  4MCB A;  1UAK A;  3ONP A;  4YQB A;  3WRP A;  2EGV A;  4CNG A;  4YPY A;  1NS5 A;  1X7O A;  4CND A;  4H3Y A;  4YVJ A;  1Z85 A;  1J85 A;  2YY8 A;  3NK6 A;  4YQ6 A;  3ILK A;  4YQ0 A;  3SSW N;  3E5Y A;  3AI9 X;  1CO0 A;  3SSX N;  1X7P A;  4YQQ A;  1UAM A;  3O7B A;  4JWG A;  3AIA A;  4JAL A;  3KY7 A;  2I6D A;  3GYQ A;  4X3L A;  4YQG A;  5GMC A;  4FMW A;  1WRS R;  4YVG A;  4CNF A;  4XBO A;  4IG6 A;  1TO0 A;  4YQO A;  2OZ9 R;  1RCS A;  4YPX A;  4YQL A;  4YQI A;  1VHY A;  2QMM A;  2Z0Y A;  4JWJ A;  4YQN A;  1GZ0 A;  4YQK A;  4RG1 A;  4YQJ A;  1K3R A;  4YPW A;  4YQ8 A;  1WRP R;  4CNE A;  1MI7 R;  3AXZ A;  4YQ5 A;  1NXZ A;  3QUV A;  4JWF A;  4YQ1 A;  3KOR A;  5CO4 A;  3L8U A;  3IC6 A;  1ZJR A;  1VH0 A;  2HA8 A;  4YVK A;  2O3A A;  4YVH A;  2XDI A;  4KGN A;  1TRO A;  5FAI A;  1IPA A;  3OIJ A;  4YQA A;  3G1C A;  4YQP A;  5D9F A;  4KDZ A;  4YQC A;  3KNU A;  4FAK A;  1JHG A;  4YQ2 A;  3DCM X;  3KTY A;  3OII A;  3IEF A;  2QWV A;  2EGW A;  2CX8 A;  4MCC A;  3N4K A;  4YQD A;  1UAJ A;  4YQ4 A;  5GM8 A;  4YQ7 A;  1UAL A;  4YQ9 A;  3N4J A;  1P9P A;  1MXI A;  4YVI A;  4X3M A;  4JWH A;  3OIN A;  4H3Z A;  4YQ3 A;  4JAK A;  4E8B A;  4L69 A;  3BBH A;  1V2X A;  3NK7 A;  4J3C A;  1WRT R;  1V6Z A;  1ZT9 A;  4YQT A;  1O6D A;  3FRW A;  4YQS A;  4YPZ A;  3BBE A;  1TRR A;  1VHK A;  2V3K A; 
#chains in the Genus database with same CATH homology
 3KW2 A;  1OY5 A;  4PZK A;  5GMB A;  2V3J A;  3BBD A;  4YQR A;  4MCD A;  4MCB A;  1UAK A;  3ONP A;  4YQB A;  2EGV A;  4CNG A;  4YPY A;  1NS5 A;  1X7O A;  4CND A;  4H3Y A;  4YVJ A;  1Z85 A;  1J85 A;  2YY8 A;  3NK6 A;  4YQ6 A;  3ILK A;  4YQ0 A;  3E5Y A;  3AI9 X;  1X7P A;  4YQQ A;  1UAM A;  3O7B A;  4JWG A;  3AIA A;  4JAL A;  3KY7 A;  2I6D A;  3GYQ A;  4X3L A;  4YQG A;  5GMC A;  4FMW A;  4YVG A;  4CNF A;  4XBO A;  4IG6 A;  1TO0 A;  4YQO A;  4YPX A;  4YQL A;  4YQI A;  1VHY A;  2QMM A;  2Z0Y A;  4JWJ A;  4YQN A;  1GZ0 A;  4YQK A;  4RG1 A;  4YQJ A;  1K3R A;  4YPW A;  4YQ8 A;  4CNE A;  3AXZ A;  4YQ5 A;  1NXZ A;  3QUV A;  4JWF A;  4YQ1 A;  5CO4 A;  3L8U A;  3IC6 A;  1ZJR A;  1VH0 A;  2HA8 A;  4YVK A;  2O3A A;  4YVH A;  4KGN A;  5FAI A;  1IPA A;  3OIJ A;  4YQA A;  4YQP A;  5D9F A;  4KDZ A;  4YQC A;  3KNU A;  4FAK A;  3DCM X;  4YQ2 A;  3KTY A;  3OII A;  3IEF A;  2QWV A;  2EGW A;  2CX8 A;  4MCC A;  3N4K A;  4YQD A;  1UAJ A;  4YQ4 A;  5GM8 A;  4YQ7 A;  1UAL A;  4YQ9 A;  3N4J A;  1P9P A;  1MXI A;  4YVI A;  4X3M A;  4JWH A;  3OIN A;  4H3Z A;  4YQ3 A;  4JAK A;  4E8B A;  4L69 A;  3BBH A;  1V2X A;  3NK7 A;  4J3C A;  1V6Z A;  4YQT A;  1O6D A;  4YQS A;  4YPZ A;  3BBE A;  1VHK A;  2V3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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