4YPWA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 67
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypwA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypwA01
1J85A 3AI9X 4YVGA 1UAMA 4L69A 4YQQA 3IEFA 4YVIA 3OIIA 3AXZA 1VHYA 3OINA 1Z85A 4YQ7A 4YQLA 2HA8A 4YQ1A 3KW2A 4YQKA 4YQPA 4XBOA 1UALA 4YQGA 3OIJA 5D9FA 4YQBA 2QMMA 4YQCA 3QUVA 1IPAA 3E5YA 3BBEA 4YQOA 2O3AA 5CO4A 3ONPA 3N4JA 3N4KA 4YQ2A 1VHKA 4H3YA 4JAKA 4CNEA 4IG6A 3IC6A 4X3LA 4YPZA 4X3MA 4H3ZA 2EGWA 2I6DA 5GMCA 2EGVA 4YQAA 3DCMX 5FAIA 3L8UA 4YQ4A 4YQ3A 4YVJA 1VH0A 4YQTA 4YVHA 3GYQA 4RG1A 1V2XA 4KDZA 4CNDA 1UAKA 5GM8A 3BBHA 4YVKA 4YQ8A 1OY5A 2V3JA 4E8BA 3NK6A 2Z0YA 4CNFA 1O6DA 5GMBA 1NS5A 2V3KA 1X7OA 3KTYA 3ILKA 4CNGA 4YQDA 4KGNA 1MXIA 1V6ZA 1ZJRA 3NK7A 4YPXA 4MCBA 1GZ0A 4MCCA 3BBDA 3O7BA 4FAKA 4YPYA 4YQIA 4YQNA 3KNUA 1TO0A 4YQRA 3AIAA 4YQ5A 1X7PA 4MCDA 1UAJA 4YQ9A 2YY8A 2QWVA 1NXZA 4JALA 4PZKA 4YQ6A 4YPWA 4YQSA 4J3CA 3KY7A 1P9PA 2CX8A 4YQJA 1K3RA 4YQ0A
chains in the Genus database with same CATH superfamily
1J85A 3FRWA 3AI9X 4YVGA 1UAMA 1CO0A 2XDIA 1RCSA 4YQQA 4L69A 3IEFA 4YVIA 4FMWA 3OIIA 3AXZA 1VHYA 3OINA 1Z85A 4YQ7A 4YQLA 2HA8A 4YQ1A 3KW2A 4YQKA 4YQPA 4XBOA 1UALA 4YQGA 3OIJA 5D9FA 4YQBA 2QMMA 4YQCA 3QUVA 1IPAA 3E5YA 4JWJA 3BBEA 4YQOA 2O3AA 5CO4A 3ONPA 3N4JA 1WRTR 3N4KA 4YQ2A 3SSXN 1VHKA 4H3YA 4JAKA 4CNEA 4IG6A 2OZ9R 3KORA 3IC6A 4X3LA 4YPZA 4X3MA 4H3ZA 2EGWA 2I6DA 5GMCA 2EGVA 4YQAA 3DCMX 5FAIA 3L8UA 4YQ4A 4YQ3A 3SSWN 4YVJA 1VH0A 4YQTA 4YVHA 3GYQA 4RG1A 1WRPR 1V2XA 4KDZA 4CNDA 1UAKA 1JHGA 5GM8A 4JWGA 3BBHA 4YVKA 4YQ8A 1OY5A 2V3JA 4E8BA 3NK6A 2Z0YA 4CNFA 4JWFA 1O6DA 5GMBA 1MI7R 1NS5A 1X7OA 2V3KA 3ILKA 3KTYA 4CNGA 4YQDA 4KGNA 1WRSR 1MXIA 4JWHA 1V6ZA 1ZJRA 3WRPA 3NK7A 4YPXA 4MCBA 1GZ0A 4MCCA 3BBDA 3G1CA 3O7BA 4FAKA 4YPYA 4YQIA 4YQNA 3KNUA 1TO0A 4YQRA 3AIAA 4YQ5A 1X7PA 4MCDA 1UAJA 4YQ9A 2YY8A 2QWVA 1NXZA 1ZT9A 4JALA 4PZKA 4YQ6A 4YPWA 4YQSA 4J3CA 3KY7A 1TROA 1TRRA 1P9PA 2CX8A 4YQJA 1K3RA 4YQ0A
chains in the Genus database with same CATH topology
1J85A 3AI9X 4YVGA 1UAMA 4L69A 4YQQA 3IEFA 4YVIA 4FMWA 3OIIA 3AXZA 1VHYA 3OINA 1Z85A 4YQ7A 4YQLA 2HA8A 4YQ1A 3KW2A 4YQKA 4YQPA 4XBOA 1UALA 4YQGA 3OIJA 5D9FA 4YQBA 2QMMA 4YQCA 3QUVA 1IPAA 3E5YA 4JWJA 3BBEA 4YQOA 2O3AA 5CO4A 3ONPA 3N4JA 3N4KA 4YQ2A 1VHKA 4H3YA 4JAKA 4CNEA 4IG6A 3IC6A 4X3LA 4YPZA 4X3MA 4H3ZA 2EGWA 2I6DA 5GMCA 2EGVA 4YQAA 3DCMX 5FAIA 3L8UA 4YQ4A 4YQ3A 4YVJA 1VH0A 4YQTA 4YVHA 3GYQA 4RG1A 1V2XA 4KDZA 4CNDA 1UAKA 5GM8A 4JWGA 3BBHA 4YVKA 4YQ8A 1OY5A 2V3JA 4E8BA 3NK6A 2Z0YA 4CNFA 4JWFA 1O6DA 5GMBA 1NS5A 2V3KA 1X7OA 3KTYA 3ILKA 4CNGA 4YQDA 4KGNA 1MXIA 4JWHA 1V6ZA 1ZJRA 3NK7A 4YPXA 4MCBA 1GZ0A 4MCCA 3BBDA 3O7BA 4FAKA 4YPYA 4YQIA 4YQNA 3KNUA 1TO0A 4YQRA 3AIAA 4YQ5A 1X7PA 4MCDA 1UAJA 4YQ9A 2YY8A 2QWVA 1NXZA 4JALA 4PZKA 4YQ6A 4YPWA 4YQSA 4J3CA 3KY7A 1P9PA 2CX8A 4YQJA 1K3RA 4YQ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J85 A;  3AI9 X;  4YVG A;  1UAM A;  4L69 A;  4YQQ A;  3IEF A;  4YVI A;  3OII A;  3AXZ A;  1VHY A;  3OIN A;  1Z85 A;  4YQ7 A;  4YQL A;  2HA8 A;  4YQ1 A;  3KW2 A;  4YQK A;  4YQP A;  4XBO A;  1UAL A;  4YQG A;  3OIJ A;  5D9F A;  4YQB A;  2QMM A;  4YQC A;  3QUV A;  1IPA A;  3E5Y A;  3BBE A;  4YQO A;  2O3A A;  5CO4 A;  3ONP A;  3N4J A;  3N4K A;  4YQ2 A;  1VHK A;  4H3Y A;  4JAK A;  4CNE A;  4IG6 A;  3IC6 A;  4X3L A;  4YPZ A;  4X3M A;  4H3Z A;  2EGW A;  2I6D A;  5GMC A;  2EGV A;  4YQA A;  3DCM X;  5FAI A;  3L8U A;  4YQ4 A;  4YQ3 A;  4YVJ A;  1VH0 A;  4YQT A;  4YVH A;  3GYQ A;  4RG1 A;  1V2X A;  4KDZ A;  4CND A;  1UAK A;  5GM8 A;  3BBH A;  4YVK A;  4YQ8 A;  1OY5 A;  2V3J A;  4E8B A;  3NK6 A;  2Z0Y A;  4CNF A;  1O6D A;  5GMB A;  1NS5 A;  2V3K A;  1X7O A;  3KTY A;  3ILK A;  4CNG A;  4YQD A;  4KGN A;  1MXI A;  1V6Z A;  1ZJR A;  3NK7 A;  4YPX A;  4MCB A;  1GZ0 A;  4MCC A;  3BBD A;  3O7B A;  4FAK A;  4YPY A;  4YQI A;  4YQN A;  3KNU A;  1TO0 A;  4YQR A;  3AIA A;  4YQ5 A;  1X7P A;  4MCD A;  1UAJ A;  4YQ9 A;  2YY8 A;  2QWV A;  1NXZ A;  4JAL A;  4PZK A;  4YQ6 A;  4YPW A;  4YQS A;  4J3C A;  3KY7 A;  1P9P A;  2CX8 A;  4YQJ A;  1K3R A;  4YQ0 A; 
#chains in the Genus database with same CATH topology
 1J85 A;  3FRW A;  3AI9 X;  4YVG A;  1UAM A;  1CO0 A;  2XDI A;  1RCS A;  4YQQ A;  4L69 A;  3IEF A;  4YVI A;  4FMW A;  3OII A;  3AXZ A;  1VHY A;  3OIN A;  1Z85 A;  4YQ7 A;  4YQL A;  2HA8 A;  4YQ1 A;  3KW2 A;  4YQK A;  4YQP A;  4XBO A;  1UAL A;  4YQG A;  3OIJ A;  5D9F A;  4YQB A;  2QMM A;  4YQC A;  3QUV A;  1IPA A;  3E5Y A;  4JWJ A;  3BBE A;  4YQO A;  2O3A A;  5CO4 A;  3ONP A;  3N4J A;  1WRT R;  3N4K A;  4YQ2 A;  3SSX N;  1VHK A;  4H3Y A;  4JAK A;  4CNE A;  4IG6 A;  2OZ9 R;  3KOR A;  3IC6 A;  4X3L A;  4YPZ A;  4X3M A;  4H3Z A;  2EGW A;  2I6D A;  5GMC A;  2EGV A;  4YQA A;  3DCM X;  5FAI A;  3L8U A;  4YQ4 A;  4YQ3 A;  3SSW N;  4YVJ A;  1VH0 A;  4YQT A;  4YVH A;  3GYQ A;  4RG1 A;  1WRP R;  1V2X A;  4KDZ A;  4CND A;  1UAK A;  1JHG A;  5GM8 A;  4JWG A;  3BBH A;  4YVK A;  4YQ8 A;  1OY5 A;  2V3J A;  4E8B A;  3NK6 A;  2Z0Y A;  4CNF A;  4JWF A;  1O6D A;  5GMB A;  1MI7 R;  1NS5 A;  1X7O A;  2V3K A;  3ILK A;  3KTY A;  4CNG A;  4YQD A;  4KGN A;  1WRS R;  1MXI A;  4JWH A;  1V6Z A;  1ZJR A;  3WRP A;  3NK7 A;  4YPX A;  4MCB A;  1GZ0 A;  4MCC A;  3BBD A;  3G1C A;  3O7B A;  4FAK A;  4YPY A;  4YQI A;  4YQN A;  3KNU A;  1TO0 A;  4YQR A;  3AIA A;  4YQ5 A;  1X7P A;  4MCD A;  1UAJ A;  4YQ9 A;  2YY8 A;  2QWV A;  1NXZ A;  1ZT9 A;  4JAL A;  4PZK A;  4YQ6 A;  4YPW A;  4YQS A;  4J3C A;  3KY7 A;  1TRO A;  1TRR A;  1P9P A;  2CX8 A;  4YQJ A;  1K3R A;  4YQ0 A; 
#chains in the Genus database with same CATH homology
 1J85 A;  3AI9 X;  4YVG A;  1UAM A;  4L69 A;  4YQQ A;  3IEF A;  4YVI A;  4FMW A;  3OII A;  3AXZ A;  1VHY A;  3OIN A;  1Z85 A;  4YQ7 A;  4YQL A;  2HA8 A;  4YQ1 A;  3KW2 A;  4YQK A;  4YQP A;  4XBO A;  1UAL A;  4YQG A;  3OIJ A;  5D9F A;  4YQB A;  2QMM A;  4YQC A;  3QUV A;  1IPA A;  3E5Y A;  4JWJ A;  3BBE A;  4YQO A;  2O3A A;  5CO4 A;  3ONP A;  3N4J A;  3N4K A;  4YQ2 A;  1VHK A;  4H3Y A;  4JAK A;  4CNE A;  4IG6 A;  3IC6 A;  4X3L A;  4YPZ A;  4X3M A;  4H3Z A;  2EGW A;  2I6D A;  5GMC A;  2EGV A;  4YQA A;  3DCM X;  5FAI A;  3L8U A;  4YQ4 A;  4YQ3 A;  4YVJ A;  1VH0 A;  4YQT A;  4YVH A;  3GYQ A;  4RG1 A;  1V2X A;  4KDZ A;  4CND A;  1UAK A;  5GM8 A;  4JWG A;  3BBH A;  4YVK A;  4YQ8 A;  1OY5 A;  2V3J A;  4E8B A;  3NK6 A;  2Z0Y A;  4CNF A;  4JWF A;  1O6D A;  5GMB A;  1NS5 A;  2V3K A;  1X7O A;  3KTY A;  3ILK A;  4CNG A;  4YQD A;  4KGN A;  1MXI A;  4JWH A;  1V6Z A;  1ZJR A;  3NK7 A;  4YPX A;  4MCB A;  1GZ0 A;  4MCC A;  3BBD A;  3O7B A;  4FAK A;  4YPY A;  4YQI A;  4YQN A;  3KNU A;  1TO0 A;  4YQR A;  3AIA A;  4YQ5 A;  1X7P A;  4MCD A;  1UAJ A;  4YQ9 A;  2YY8 A;  2QWV A;  1NXZ A;  4JAL A;  4PZK A;  4YQ6 A;  4YPW A;  4YQS A;  4J3C A;  3KY7 A;  1P9P A;  2CX8 A;  4YQJ A;  1K3R A;  4YQ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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