4YPWA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 67
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypwA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypwA01
4YQ4A 3BBDA 3OIIA 4YPXA 2EGVA 1VHYA 3IEFA 1GZ0A 1TO0A 3BBEA 3KW2A 4CNEA 4YQ2A 1VHKA 1V6ZA 1ZJRA 2YY8A 4MCBA 4E8BA 4KGNA 3N4KA 3BBHA 4YQKA 4YQQA 3N4JA 1VH0A 2V3KA 4J3CA 2EGWA 4XBOA 3AXZA 3ILKA 4YQ0A 2I6DA 2Z0YA 4YPWA 1K3RA 4YQGA 4YQTA 1X7OA 2HA8A 4RG1A 4MCCA 4YQCA 4YQIA 4JALA 1V2XA 4CNDA 4YVKA 3KY7A 4YQBA 1UAMA 4YQDA 1NXZA 3DCMX 1OY5A 3KTYA 5GMCA 5GM8A 4YVGA 4YQNA 3KNUA 5CO4A 4CNFA 4KDZA 4YQPA 2QWVA 1UAKA 4YPZA 4YQAA 4YPYA 4YQ9A 4L69A 4YVHA 3L8UA 3AIAA 4CNGA 4YQ3A 3OIJA 4H3ZA 1IPAA 4YQJA 2QMMA 3NK7A 4X3MA 4YVJA 2O3AA 4H3YA 3E5YA 3ONPA 4MCDA 3NK6A 4YQ5A 2V3JA 4IG6A 4X3LA 1Z85A 4YQ1A 4YQRA 4YQ7A 1O6DA 4YQLA 2CX8A 3OINA 4YQOA 4YQ6A 4YVIA 1J85A 1MXIA 3IC6A 3O7BA 1P9PA 3AI9X 4JAKA 3GYQA 5GMBA 4FAKA 4YQ8A 1X7PA 4YQSA 5FAIA 3QUVA 1UALA 5D9FA 4PZKA 1NS5A 1UAJA
chains in the Genus database with same CATH superfamily
4YQ4A 3BBDA 3OIIA 4YPXA 2EGVA 1JHGA 4JWGA 1VHYA 3IEFA 1GZ0A 1TO0A 3BBEA 3KW2A 4CNEA 4YQ2A 1VHKA 3G1CA 1V6ZA 1ZJRA 2YY8A 4MCBA 4E8BA 1TROA 3SSWN 4KGNA 3N4KA 3BBHA 4YQKA 4YQQA 3N4JA 1VH0A 2V3KA 4J3CA 2EGWA 4XBOA 3AXZA 3ILKA 4YQ0A 2I6DA 2Z0YA 4YPWA 1K3RA 4YQGA 4YQTA 1X7OA 2HA8A 4RG1A 4MCCA 4YQCA 4YQIA 4JALA 2OZ9R 1V2XA 4CNDA 4YVKA 1TRRA 3KY7A 4YQBA 1UAMA 4YQDA 1WRSR 1NXZA 1WRTR 3DCMX 1OY5A 3KTYA 5GMCA 5GM8A 4YVGA 4YQNA 1RCSA 3KNUA 5CO4A 4CNFA 4KDZA 1MI7R 4YQPA 2QWVA 1UAKA 4YPZA 2XDIA 4YQAA 4JWHA 4YPYA 4YQ9A 4L69A 4YVHA 3L8UA 1ZT9A 3AIAA 4CNGA 4YQ3A 3OIJA 4H3ZA 1IPAA 3WRPA 4YQJA 2QMMA 3NK7A 1CO0A 4X3MA 4YVJA 2O3AA 3SSXN 4H3YA 4FMWA 3E5YA 3ONPA 4MCDA 3NK6A 4YQ5A 2V3JA 4IG6A 4X3LA 1Z85A 4YQ1A 4YQRA 4YQ7A 1O6DA 4YQLA 3FRWA 2CX8A 3OINA 1WRPR 4YQOA 4YQ6A 4YVIA 1J85A 1MXIA 3IC6A 3O7BA 4JWJA 1P9PA 4JWFA 3AI9X 4JAKA 3GYQA 5GMBA 4FAKA 4YQ8A 1X7PA 4YQSA 5FAIA 3QUVA 1UALA 5D9FA 3KORA 4PZKA 1NS5A 1UAJA
chains in the Genus database with same CATH topology
4YQ4A 3BBDA 3OIIA 4YPXA 2EGVA 4JWGA 1VHYA 3IEFA 1GZ0A 1TO0A 3BBEA 3KW2A 4CNEA 4YQ2A 1VHKA 1V6ZA 1ZJRA 2YY8A 4MCBA 4E8BA 4KGNA 3N4KA 3BBHA 4YQKA 4YQQA 3N4JA 1VH0A 2V3KA 4J3CA 2EGWA 4XBOA 3AXZA 3ILKA 4YQ0A 2I6DA 2Z0YA 4YPWA 1K3RA 4YQGA 4YQTA 1X7OA 2HA8A 4RG1A 4MCCA 4YQCA 4YQIA 4JALA 1V2XA 4CNDA 4YVKA 3KY7A 4YQBA 1UAMA 4YQDA 1NXZA 3DCMX 1OY5A 3KTYA 5GMCA 5GM8A 4YVGA 4YQNA 3KNUA 5CO4A 4CNFA 4KDZA 4YQPA 2QWVA 1UAKA 4YPZA 4YQAA 4JWHA 4YPYA 4YQ9A 4L69A 4YVHA 3L8UA 3AIAA 4CNGA 4YQ3A 3OIJA 4H3ZA 1IPAA 4YQJA 2QMMA 3NK7A 4X3MA 4YVJA 2O3AA 4H3YA 4FMWA 3E5YA 3ONPA 4MCDA 3NK6A 4YQ5A 2V3JA 4IG6A 4X3LA 1Z85A 4YQ1A 4YQRA 4YQ7A 1O6DA 4YQLA 2CX8A 3OINA 4YQOA 4YQ6A 4YVIA 1J85A 1MXIA 3IC6A 3O7BA 4JWJA 1P9PA 4JWFA 3AI9X 4JAKA 3GYQA 5GMBA 4FAKA 4YQ8A 1X7PA 4YQSA 5FAIA 3QUVA 1UALA 5D9FA 4PZKA 1NS5A 1UAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ4 A;  3BBD A;  3OII A;  4YPX A;  2EGV A;  1VHY A;  3IEF A;  1GZ0 A;  1TO0 A;  3BBE A;  3KW2 A;  4CNE A;  4YQ2 A;  1VHK A;  1V6Z A;  1ZJR A;  2YY8 A;  4MCB A;  4E8B A;  4KGN A;  3N4K A;  3BBH A;  4YQK A;  4YQQ A;  3N4J A;  1VH0 A;  2V3K A;  4J3C A;  2EGW A;  4XBO A;  3AXZ A;  3ILK A;  4YQ0 A;  2I6D A;  2Z0Y A;  4YPW A;  1K3R A;  4YQG A;  4YQT A;  1X7O A;  2HA8 A;  4RG1 A;  4MCC A;  4YQC A;  4YQI A;  4JAL A;  1V2X A;  4CND A;  4YVK A;  3KY7 A;  4YQB A;  1UAM A;  4YQD A;  1NXZ A;  3DCM X;  1OY5 A;  3KTY A;  5GMC A;  5GM8 A;  4YVG A;  4YQN A;  3KNU A;  5CO4 A;  4CNF A;  4KDZ A;  4YQP A;  2QWV A;  1UAK A;  4YPZ A;  4YQA A;  4YPY A;  4YQ9 A;  4L69 A;  4YVH A;  3L8U A;  3AIA A;  4CNG A;  4YQ3 A;  3OIJ A;  4H3Z A;  1IPA A;  4YQJ A;  2QMM A;  3NK7 A;  4X3M A;  4YVJ A;  2O3A A;  4H3Y A;  3E5Y A;  3ONP A;  4MCD A;  3NK6 A;  4YQ5 A;  2V3J A;  4IG6 A;  4X3L A;  1Z85 A;  4YQ1 A;  4YQR A;  4YQ7 A;  1O6D A;  4YQL A;  2CX8 A;  3OIN A;  4YQO A;  4YQ6 A;  4YVI A;  1J85 A;  1MXI A;  3IC6 A;  3O7B A;  1P9P A;  3AI9 X;  4JAK A;  3GYQ A;  5GMB A;  4FAK A;  4YQ8 A;  1X7P A;  4YQS A;  5FAI A;  3QUV A;  1UAL A;  5D9F A;  4PZK A;  1NS5 A;  1UAJ A; 
#chains in the Genus database with same CATH topology
 4YQ4 A;  3BBD A;  3OII A;  4YPX A;  2EGV A;  1JHG A;  4JWG A;  1VHY A;  3IEF A;  1GZ0 A;  1TO0 A;  3BBE A;  3KW2 A;  4CNE A;  4YQ2 A;  1VHK A;  3G1C A;  1V6Z A;  1ZJR A;  2YY8 A;  4MCB A;  4E8B A;  1TRO A;  3SSW N;  4KGN A;  3N4K A;  3BBH A;  4YQK A;  4YQQ A;  3N4J A;  1VH0 A;  2V3K A;  4J3C A;  2EGW A;  4XBO A;  3AXZ A;  3ILK A;  4YQ0 A;  2I6D A;  2Z0Y A;  4YPW A;  1K3R A;  4YQG A;  4YQT A;  1X7O A;  2HA8 A;  4RG1 A;  4MCC A;  4YQC A;  4YQI A;  4JAL A;  2OZ9 R;  1V2X A;  4CND A;  4YVK A;  1TRR A;  3KY7 A;  4YQB A;  1UAM A;  4YQD A;  1WRS R;  1NXZ A;  1WRT R;  3DCM X;  1OY5 A;  3KTY A;  5GMC A;  5GM8 A;  4YVG A;  4YQN A;  1RCS A;  3KNU A;  5CO4 A;  4CNF A;  4KDZ A;  1MI7 R;  4YQP A;  2QWV A;  1UAK A;  4YPZ A;  2XDI A;  4YQA A;  4JWH A;  4YPY A;  4YQ9 A;  4L69 A;  4YVH A;  3L8U A;  1ZT9 A;  3AIA A;  4CNG A;  4YQ3 A;  3OIJ A;  4H3Z A;  1IPA A;  3WRP A;  4YQJ A;  2QMM A;  3NK7 A;  1CO0 A;  4X3M A;  4YVJ A;  2O3A A;  3SSX N;  4H3Y A;  4FMW A;  3E5Y A;  3ONP A;  4MCD A;  3NK6 A;  4YQ5 A;  2V3J A;  4IG6 A;  4X3L A;  1Z85 A;  4YQ1 A;  4YQR A;  4YQ7 A;  1O6D A;  4YQL A;  3FRW A;  2CX8 A;  3OIN A;  1WRP R;  4YQO A;  4YQ6 A;  4YVI A;  1J85 A;  1MXI A;  3IC6 A;  3O7B A;  4JWJ A;  1P9P A;  4JWF A;  3AI9 X;  4JAK A;  3GYQ A;  5GMB A;  4FAK A;  4YQ8 A;  1X7P A;  4YQS A;  5FAI A;  3QUV A;  1UAL A;  5D9F A;  3KOR A;  4PZK A;  1NS5 A;  1UAJ A; 
#chains in the Genus database with same CATH homology
 4YQ4 A;  3BBD A;  3OII A;  4YPX A;  2EGV A;  4JWG A;  1VHY A;  3IEF A;  1GZ0 A;  1TO0 A;  3BBE A;  3KW2 A;  4CNE A;  4YQ2 A;  1VHK A;  1V6Z A;  1ZJR A;  2YY8 A;  4MCB A;  4E8B A;  4KGN A;  3N4K A;  3BBH A;  4YQK A;  4YQQ A;  3N4J A;  1VH0 A;  2V3K A;  4J3C A;  2EGW A;  4XBO A;  3AXZ A;  3ILK A;  4YQ0 A;  2I6D A;  2Z0Y A;  4YPW A;  1K3R A;  4YQG A;  4YQT A;  1X7O A;  2HA8 A;  4RG1 A;  4MCC A;  4YQC A;  4YQI A;  4JAL A;  1V2X A;  4CND A;  4YVK A;  3KY7 A;  4YQB A;  1UAM A;  4YQD A;  1NXZ A;  3DCM X;  1OY5 A;  3KTY A;  5GMC A;  5GM8 A;  4YVG A;  4YQN A;  3KNU A;  5CO4 A;  4CNF A;  4KDZ A;  4YQP A;  2QWV A;  1UAK A;  4YPZ A;  4YQA A;  4JWH A;  4YPY A;  4YQ9 A;  4L69 A;  4YVH A;  3L8U A;  3AIA A;  4CNG A;  4YQ3 A;  3OIJ A;  4H3Z A;  1IPA A;  4YQJ A;  2QMM A;  3NK7 A;  4X3M A;  4YVJ A;  2O3A A;  4H3Y A;  4FMW A;  3E5Y A;  3ONP A;  4MCD A;  3NK6 A;  4YQ5 A;  2V3J A;  4IG6 A;  4X3L A;  1Z85 A;  4YQ1 A;  4YQR A;  4YQ7 A;  1O6D A;  4YQL A;  2CX8 A;  3OIN A;  4YQO A;  4YQ6 A;  4YVI A;  1J85 A;  1MXI A;  3IC6 A;  3O7B A;  4JWJ A;  1P9P A;  4JWF A;  3AI9 X;  4JAK A;  3GYQ A;  5GMB A;  4FAK A;  4YQ8 A;  1X7P A;  4YQS A;  5FAI A;  3QUV A;  1UAL A;  5D9F A;  4PZK A;  1NS5 A;  1UAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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