4YPXA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 74
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
Knots found
sequence length
249
structure length
239
Chain Sequence
RGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 74
structure length 239
sequence length 249
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypxA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypxA01
1P9PA 3BBEA 4YQ3A 4J3CA 3N4KA 4YQGA 1VH0A 3OINA 3KTYA 3IEFA 4X3LA 4YQIA 2I6DA 1TO0A 1VHYA 2QMMA 3L8UA 4KDZA 4IG6A 1MXIA 1NS5A 2EGVA 3BBDA 4YQ1A 5FAIA 4XBOA 3NK6A 1NXZA 4YQ9A 4KGNA 4YVGA 4YQ6A 4E8BA 5GMBA 4YQ0A 2EGWA 4CNFA 4YQOA 1O6DA 3AIAA 1X7PA 3OIJA 4JAKA 4YQRA 4YQDA 3AI9X 4YQTA 1UAKA 4PZKA 2Z0YA 4JALA 1Z85A 4YQLA 3ILKA 5GM8A 3ONPA 1V6ZA 4YQ8A 4H3YA 5D9FA 4YPZA 3N4JA 2HA8A 3NK7A 1K3RA 2YY8A 4YQAA 4YQNA 5CO4A 4FAKA 1J85A 4YVIA 2O3AA 2V3KA 4CNDA 4CNGA 4CNEA 4RG1A 4YPYA 1IPAA 4YQQA 4YQPA 4YQJA 4YQ2A 3E5YA 5GMCA 3QUVA 4MCBA 2CX8A 1GZ0A 4YQSA 1UAMA 1OY5A 4YQ7A 4YQKA 4YVHA 3BBHA 3DCMX 3IC6A 4YVJA 1V2XA 4YQCA 3GYQA 4MCCA 1ZJRA 4YVKA 4MCDA 2V3JA 4L69A 4YQBA 1UALA 3OIIA 4YPWA 1VHKA 1X7OA 3KW2A 3KY7A 4YPXA 3O7BA 4YQ5A 3AXZA 4X3MA 4YQ4A 2QWVA 1UAJA 3KNUA 4H3ZA
chains in the Genus database with same CATH superfamily
1P9PA 3BBEA 4YQ3A 4J3CA 3N4KA 1ZT9A 4YQGA 1VH0A 3OINA 3KTYA 3IEFA 3G1CA 4X3LA 4YQIA 2I6DA 1TO0A 1VHYA 2QMMA 3L8UA 4KDZA 1TROA 4IG6A 1MXIA 1NS5A 2EGVA 3BBDA 4YQ1A 5FAIA 4XBOA 3NK6A 4JWFA 1NXZA 4YQ9A 4KGNA 4YVGA 4YQ6A 4E8BA 5GMBA 4YQ0A 2EGWA 1WRTR 4CNFA 4YQOA 1O6DA 3AIAA 1X7PA 3OIJA 4JAKA 4YQRA 4YQDA 1TRRA 3AI9X 4YQTA 1UAKA 4PZKA 2Z0YA 4JALA 1Z85A 4YQLA 3ILKA 5GM8A 3ONPA 1V6ZA 4YQ8A 4FMWA 1WRSR 4H3YA 5D9FA 4YPZA 1JHGA 3N4JA 2HA8A 3NK7A 1K3RA 2YY8A 4YQAA 3SSXN 3KORA 4YQNA 5CO4A 4FAKA 1J85A 4YVIA 2O3AA 2V3KA 4CNDA 4CNGA 4CNEA 4RG1A 4YPYA 2OZ9R 1CO0A 1IPAA 4JWJA 4YQQA 4YQPA 4YQJA 4YQ2A 3E5YA 5GMCA 3SSWN 3QUVA 4JWHA 4MCBA 2CX8A 3WRPA 1GZ0A 4YQSA 3FRWA 1UAMA 1OY5A 4YQ7A 4JWGA 4YQKA 4YVHA 3BBHA 3DCMX 3IC6A 4YVJA 1V2XA 4YQCA 3GYQA 4MCCA 1ZJRA 4YVKA 4MCDA 1RCSA 2V3JA 4L69A 2XDIA 4YQBA 1UALA 3OIIA 4YPWA 1VHKA 1X7OA 3KW2A 1MI7R 3KY7A 4YPXA 3O7BA 4YQ5A 3AXZA 4X3MA 1WRPR 4YQ4A 2QWVA 1UAJA 3KNUA 4H3ZA
chains in the Genus database with same CATH topology
1P9PA 3BBEA 4YQ3A 4J3CA 3N4KA 4YQGA 1VH0A 3OINA 3KTYA 3IEFA 4X3LA 4YQIA 2I6DA 1TO0A 1VHYA 2QMMA 3L8UA 4KDZA 4IG6A 1MXIA 1NS5A 2EGVA 3BBDA 4YQ1A 5FAIA 4XBOA 3NK6A 4JWFA 1NXZA 4YQ9A 4KGNA 4YVGA 4YQ6A 4E8BA 5GMBA 4YQ0A 2EGWA 4CNFA 4YQOA 1O6DA 3AIAA 1X7PA 3OIJA 4JAKA 4YQRA 4YQDA 3AI9X 4YQTA 1UAKA 4PZKA 2Z0YA 4JALA 1Z85A 4YQLA 3ILKA 5GM8A 3ONPA 1V6ZA 4YQ8A 4FMWA 4H3YA 5D9FA 4YPZA 3N4JA 2HA8A 3NK7A 1K3RA 2YY8A 4YQAA 4YQNA 5CO4A 4FAKA 1J85A 4YVIA 2O3AA 2V3KA 4CNDA 4CNGA 4CNEA 4RG1A 4YPYA 1IPAA 4JWJA 4YQQA 4YQPA 4YQJA 4YQ2A 3E5YA 5GMCA 3QUVA 4JWHA 4MCBA 2CX8A 1GZ0A 4YQSA 1UAMA 1OY5A 4YQ7A 4JWGA 4YQKA 4YVHA 3BBHA 3DCMX 3IC6A 4YVJA 1V2XA 4YQCA 3GYQA 4MCCA 1ZJRA 4YVKA 4MCDA 2V3JA 4L69A 4YQBA 1UALA 3OIIA 4YPWA 1VHKA 1X7OA 3KW2A 3KY7A 4YPXA 3O7BA 4YQ5A 3AXZA 4X3MA 4YQ4A 2QWVA 1UAJA 3KNUA 4H3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P9P A;  3BBE A;  4YQ3 A;  4J3C A;  3N4K A;  4YQG A;  1VH0 A;  3OIN A;  3KTY A;  3IEF A;  4X3L A;  4YQI A;  2I6D A;  1TO0 A;  1VHY A;  2QMM A;  3L8U A;  4KDZ A;  4IG6 A;  1MXI A;  1NS5 A;  2EGV A;  3BBD A;  4YQ1 A;  5FAI A;  4XBO A;  3NK6 A;  1NXZ A;  4YQ9 A;  4KGN A;  4YVG A;  4YQ6 A;  4E8B A;  5GMB A;  4YQ0 A;  2EGW A;  4CNF A;  4YQO A;  1O6D A;  3AIA A;  1X7P A;  3OIJ A;  4JAK A;  4YQR A;  4YQD A;  3AI9 X;  4YQT A;  1UAK A;  4PZK A;  2Z0Y A;  4JAL A;  1Z85 A;  4YQL A;  3ILK A;  5GM8 A;  3ONP A;  1V6Z A;  4YQ8 A;  4H3Y A;  5D9F A;  4YPZ A;  3N4J A;  2HA8 A;  3NK7 A;  1K3R A;  2YY8 A;  4YQA A;  4YQN A;  5CO4 A;  4FAK A;  1J85 A;  4YVI A;  2O3A A;  2V3K A;  4CND A;  4CNG A;  4CNE A;  4RG1 A;  4YPY A;  1IPA A;  4YQQ A;  4YQP A;  4YQJ A;  4YQ2 A;  3E5Y A;  5GMC A;  3QUV A;  4MCB A;  2CX8 A;  1GZ0 A;  4YQS A;  1UAM A;  1OY5 A;  4YQ7 A;  4YQK A;  4YVH A;  3BBH A;  3DCM X;  3IC6 A;  4YVJ A;  1V2X A;  4YQC A;  3GYQ A;  4MCC A;  1ZJR A;  4YVK A;  4MCD A;  2V3J A;  4L69 A;  4YQB A;  1UAL A;  3OII A;  4YPW A;  1VHK A;  1X7O A;  3KW2 A;  3KY7 A;  4YPX A;  3O7B A;  4YQ5 A;  3AXZ A;  4X3M A;  4YQ4 A;  2QWV A;  1UAJ A;  3KNU A;  4H3Z A; 
#chains in the Genus database with same CATH topology
 1P9P A;  3BBE A;  4YQ3 A;  4J3C A;  3N4K A;  1ZT9 A;  4YQG A;  1VH0 A;  3OIN A;  3KTY A;  3IEF A;  3G1C A;  4X3L A;  4YQI A;  2I6D A;  1TO0 A;  1VHY A;  2QMM A;  3L8U A;  4KDZ A;  1TRO A;  4IG6 A;  1MXI A;  1NS5 A;  2EGV A;  3BBD A;  4YQ1 A;  5FAI A;  4XBO A;  3NK6 A;  4JWF A;  1NXZ A;  4YQ9 A;  4KGN A;  4YVG A;  4YQ6 A;  4E8B A;  5GMB A;  4YQ0 A;  2EGW A;  1WRT R;  4CNF A;  4YQO A;  1O6D A;  3AIA A;  1X7P A;  3OIJ A;  4JAK A;  4YQR A;  4YQD A;  1TRR A;  3AI9 X;  4YQT A;  1UAK A;  4PZK A;  2Z0Y A;  4JAL A;  1Z85 A;  4YQL A;  3ILK A;  5GM8 A;  3ONP A;  1V6Z A;  4YQ8 A;  4FMW A;  1WRS R;  4H3Y A;  5D9F A;  4YPZ A;  1JHG A;  3N4J A;  2HA8 A;  3NK7 A;  1K3R A;  2YY8 A;  4YQA A;  3SSX N;  3KOR A;  4YQN A;  5CO4 A;  4FAK A;  1J85 A;  4YVI A;  2O3A A;  2V3K A;  4CND A;  4CNG A;  4CNE A;  4RG1 A;  4YPY A;  2OZ9 R;  1CO0 A;  1IPA A;  4JWJ A;  4YQQ A;  4YQP A;  4YQJ A;  4YQ2 A;  3E5Y A;  5GMC A;  3SSW N;  3QUV A;  4JWH A;  4MCB A;  2CX8 A;  3WRP A;  1GZ0 A;  4YQS A;  3FRW A;  1UAM A;  1OY5 A;  4YQ7 A;  4JWG A;  4YQK A;  4YVH A;  3BBH A;  3DCM X;  3IC6 A;  4YVJ A;  1V2X A;  4YQC A;  3GYQ A;  4MCC A;  1ZJR A;  4YVK A;  4MCD A;  1RCS A;  2V3J A;  4L69 A;  2XDI A;  4YQB A;  1UAL A;  3OII A;  4YPW A;  1VHK A;  1X7O A;  3KW2 A;  1MI7 R;  3KY7 A;  4YPX A;  3O7B A;  4YQ5 A;  3AXZ A;  4X3M A;  1WRP R;  4YQ4 A;  2QWV A;  1UAJ A;  3KNU A;  4H3Z A; 
#chains in the Genus database with same CATH homology
 1P9P A;  3BBE A;  4YQ3 A;  4J3C A;  3N4K A;  4YQG A;  1VH0 A;  3OIN A;  3KTY A;  3IEF A;  4X3L A;  4YQI A;  2I6D A;  1TO0 A;  1VHY A;  2QMM A;  3L8U A;  4KDZ A;  4IG6 A;  1MXI A;  1NS5 A;  2EGV A;  3BBD A;  4YQ1 A;  5FAI A;  4XBO A;  3NK6 A;  4JWF A;  1NXZ A;  4YQ9 A;  4KGN A;  4YVG A;  4YQ6 A;  4E8B A;  5GMB A;  4YQ0 A;  2EGW A;  4CNF A;  4YQO A;  1O6D A;  3AIA A;  1X7P A;  3OIJ A;  4JAK A;  4YQR A;  4YQD A;  3AI9 X;  4YQT A;  1UAK A;  4PZK A;  2Z0Y A;  4JAL A;  1Z85 A;  4YQL A;  3ILK A;  5GM8 A;  3ONP A;  1V6Z A;  4YQ8 A;  4FMW A;  4H3Y A;  5D9F A;  4YPZ A;  3N4J A;  2HA8 A;  3NK7 A;  1K3R A;  2YY8 A;  4YQA A;  4YQN A;  5CO4 A;  4FAK A;  1J85 A;  4YVI A;  2O3A A;  2V3K A;  4CND A;  4CNG A;  4CNE A;  4RG1 A;  4YPY A;  1IPA A;  4JWJ A;  4YQQ A;  4YQP A;  4YQJ A;  4YQ2 A;  3E5Y A;  5GMC A;  3QUV A;  4JWH A;  4MCB A;  2CX8 A;  1GZ0 A;  4YQS A;  1UAM A;  1OY5 A;  4YQ7 A;  4JWG A;  4YQK A;  4YVH A;  3BBH A;  3DCM X;  3IC6 A;  4YVJ A;  1V2X A;  4YQC A;  3GYQ A;  4MCC A;  1ZJR A;  4YVK A;  4MCD A;  2V3J A;  4L69 A;  4YQB A;  1UAL A;  3OII A;  4YPW A;  1VHK A;  1X7O A;  3KW2 A;  3KY7 A;  4YPX A;  3O7B A;  4YQ5 A;  3AXZ A;  4X3M A;  4YQ4 A;  2QWV A;  1UAJ A;  3KNU A;  4H3Z A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...