4YPYA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
248
structure length
239
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 74
structure length 239
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypyA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypyA01
1NXZA 3AIAA 4YQNA 3BBEA 4YQ2A 4PZKA 4YQPA 4YQ1A 1TO0A 4YQ0A 2V3JA 4CNFA 3BBDA 3E5YA 4XBOA 4YQ5A 3BBHA 1V6ZA 1P9PA 1UAMA 1MXIA 1K3RA 3ILKA 4YQRA 4YQGA 3KNUA 4YQ6A 4YQTA 4YQ3A 2CX8A 1Z85A 1VHYA 4YQLA 1OY5A 3DCMX 1VHKA 2QMMA 4H3ZA 3L8UA 4JALA 4JAKA 1IPAA 3ONPA 5FAIA 5GMBA 4YQKA 5GMCA 1ZJRA 3OIIA 3N4JA 4YQDA 4YQ8A 4X3LA 4MCBA 2HA8A 2EGVA 4YQSA 4YQ7A 3NK7A 1UAKA 1J85A 4YVGA 4YQJA 4J3CA 3NK6A 1UALA 4YQ4A 3IEFA 4H3YA 1VH0A 3N4KA 3GYQA 4KGNA 4YPYA 3O7BA 4L69A 1NS5A 3AXZA 4YQOA 2I6DA 2Z0YA 1V2XA 3AI9X 4CNEA 4YPWA 2EGWA 4MCCA 2O3AA 4FAKA 4YVKA 4E8BA 4YVJA 4YQ9A 4MCDA 4CNDA 4YVIA 4CNGA 3OINA 5D9FA 4YPXA 4YQCA 4X3MA 4IG6A 3KTYA 1GZ0A 4YVHA 2V3KA 5CO4A 3KW2A 4KDZA 4YQBA 2QWVA 3IC6A 3OIJA 4YQAA 5GM8A 2YY8A 4YQQA 1X7PA 3QUVA 1X7OA 4YQIA 1UAJA 1O6DA 4YPZA 3KY7A 4RG1A
chains in the Genus database with same CATH superfamily
1NXZA 3AIAA 4YQNA 3BBEA 4YQ2A 4PZKA 4YQPA 4YQ1A 1TO0A 4YQ0A 2V3JA 4CNFA 3BBDA 3E5YA 4XBOA 4YQ5A 3BBHA 3G1CA 1JHGA 1V6ZA 1P9PA 1UAMA 1MXIA 1K3RA 3ILKA 4YQRA 4YQGA 2OZ9R 3KNUA 4YQ6A 4YQTA 4YQ3A 4JWJA 2CX8A 1Z85A 1WRTR 3WRPA 1VHYA 4YQLA 1OY5A 3DCMX 1VHKA 2QMMA 4H3ZA 3L8UA 4JALA 4JAKA 1IPAA 3ONPA 5FAIA 5GMBA 4YQKA 5GMCA 1ZJRA 2XDIA 3OIIA 3N4JA 4YQDA 4YQ8A 4X3LA 4MCBA 2HA8A 2EGVA 4JWFA 4YQSA 4YQ7A 3NK7A 1UAKA 1J85A 4YVGA 4YQJA 4J3CA 1CO0A 1UALA 3NK6A 4YQ4A 4FMWA 3IEFA 4H3YA 1VH0A 3N4KA 3GYQA 4KGNA 4YPYA 3O7BA 4L69A 1NS5A 3AXZA 4YQOA 1RCSA 2I6DA 2Z0YA 1V2XA 3AI9X 4CNEA 4YPWA 2EGWA 4MCCA 2O3AA 4FAKA 4YVKA 4E8BA 4YVJA 4YQ9A 4MCDA 4CNDA 4JWGA 4YVIA 3SSXN 4CNGA 3OINA 5D9FA 4YPXA 4YQCA 3SSWN 1WRPR 1ZT9A 4X3MA 4IG6A 3KTYA 1GZ0A 4YVHA 2V3KA 5CO4A 3KW2A 4KDZA 4YQBA 2QWVA 3IC6A 3OIJA 4YQAA 5GM8A 2YY8A 4YQQA 3KORA 1X7PA 3QUVA 1X7OA 1TROA 4YQIA 1UAJA 1MI7R 3FRWA 4JWHA 1O6DA 1WRSR 4YPZA 3KY7A 1TRRA 4RG1A
chains in the Genus database with same CATH topology
1NXZA 3AIAA 4YQNA 3BBEA 4YQ2A 4PZKA 4YQPA 4YQ1A 1TO0A 4YQ0A 2V3JA 4CNFA 3BBDA 3E5YA 4XBOA 4YQ5A 3BBHA 1V6ZA 1P9PA 1UAMA 1MXIA 1K3RA 3ILKA 4YQRA 4YQGA 3KNUA 4YQ6A 4YQTA 4YQ3A 4JWJA 2CX8A 1Z85A 1VHYA 4YQLA 1OY5A 3DCMX 1VHKA 2QMMA 4H3ZA 3L8UA 4JALA 4JAKA 1IPAA 3ONPA 5FAIA 5GMBA 4YQKA 5GMCA 1ZJRA 3OIIA 3N4JA 4YQDA 4YQ8A 4X3LA 4MCBA 2HA8A 2EGVA 4JWFA 4YQSA 4YQ7A 3NK7A 1UAKA 1J85A 4YVGA 4YQJA 4J3CA 3NK6A 1UALA 4YQ4A 4FMWA 3IEFA 4H3YA 1VH0A 3N4KA 3GYQA 4KGNA 4YPYA 3O7BA 4L69A 1NS5A 3AXZA 4YQOA 2I6DA 2Z0YA 1V2XA 3AI9X 4CNEA 4YPWA 2EGWA 4MCCA 2O3AA 4FAKA 4YVKA 4E8BA 4YVJA 4YQ9A 4MCDA 4CNDA 4JWGA 4YVIA 4CNGA 3OINA 5D9FA 4YPXA 4YQCA 4X3MA 4IG6A 3KTYA 1GZ0A 4YVHA 2V3KA 5CO4A 3KW2A 4KDZA 4YQBA 2QWVA 3IC6A 3OIJA 4YQAA 5GM8A 2YY8A 4YQQA 1X7PA 3QUVA 1X7OA 4YQIA 1UAJA 4JWHA 1O6DA 4YPZA 3KY7A 4RG1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NXZ A;  3AIA A;  4YQN A;  3BBE A;  4YQ2 A;  4PZK A;  4YQP A;  4YQ1 A;  1TO0 A;  4YQ0 A;  2V3J A;  4CNF A;  3BBD A;  3E5Y A;  4XBO A;  4YQ5 A;  3BBH A;  1V6Z A;  1P9P A;  1UAM A;  1MXI A;  1K3R A;  3ILK A;  4YQR A;  4YQG A;  3KNU A;  4YQ6 A;  4YQT A;  4YQ3 A;  2CX8 A;  1Z85 A;  1VHY A;  4YQL A;  1OY5 A;  3DCM X;  1VHK A;  2QMM A;  4H3Z A;  3L8U A;  4JAL A;  4JAK A;  1IPA A;  3ONP A;  5FAI A;  5GMB A;  4YQK A;  5GMC A;  1ZJR A;  3OII A;  3N4J A;  4YQD A;  4YQ8 A;  4X3L A;  4MCB A;  2HA8 A;  2EGV A;  4YQS A;  4YQ7 A;  3NK7 A;  1UAK A;  1J85 A;  4YVG A;  4YQJ A;  4J3C A;  3NK6 A;  1UAL A;  4YQ4 A;  3IEF A;  4H3Y A;  1VH0 A;  3N4K A;  3GYQ A;  4KGN A;  4YPY A;  3O7B A;  4L69 A;  1NS5 A;  3AXZ A;  4YQO A;  2I6D A;  2Z0Y A;  1V2X A;  3AI9 X;  4CNE A;  4YPW A;  2EGW A;  4MCC A;  2O3A A;  4FAK A;  4YVK A;  4E8B A;  4YVJ A;  4YQ9 A;  4MCD A;  4CND A;  4YVI A;  4CNG A;  3OIN A;  5D9F A;  4YPX A;  4YQC A;  4X3M A;  4IG6 A;  3KTY A;  1GZ0 A;  4YVH A;  2V3K A;  5CO4 A;  3KW2 A;  4KDZ A;  4YQB A;  2QWV A;  3IC6 A;  3OIJ A;  4YQA A;  5GM8 A;  2YY8 A;  4YQQ A;  1X7P A;  3QUV A;  1X7O A;  4YQI A;  1UAJ A;  1O6D A;  4YPZ A;  3KY7 A;  4RG1 A; 
#chains in the Genus database with same CATH topology
 1NXZ A;  3AIA A;  4YQN A;  3BBE A;  4YQ2 A;  4PZK A;  4YQP A;  4YQ1 A;  1TO0 A;  4YQ0 A;  2V3J A;  4CNF A;  3BBD A;  3E5Y A;  4XBO A;  4YQ5 A;  3BBH A;  3G1C A;  1JHG A;  1V6Z A;  1P9P A;  1UAM A;  1MXI A;  1K3R A;  3ILK A;  4YQR A;  4YQG A;  2OZ9 R;  3KNU A;  4YQ6 A;  4YQT A;  4YQ3 A;  4JWJ A;  2CX8 A;  1Z85 A;  1WRT R;  3WRP A;  1VHY A;  4YQL A;  1OY5 A;  3DCM X;  1VHK A;  2QMM A;  4H3Z A;  3L8U A;  4JAL A;  4JAK A;  1IPA A;  3ONP A;  5FAI A;  5GMB A;  4YQK A;  5GMC A;  1ZJR A;  2XDI A;  3OII A;  3N4J A;  4YQD A;  4YQ8 A;  4X3L A;  4MCB A;  2HA8 A;  2EGV A;  4JWF A;  4YQS A;  4YQ7 A;  3NK7 A;  1UAK A;  1J85 A;  4YVG A;  4YQJ A;  4J3C A;  1CO0 A;  1UAL A;  3NK6 A;  4YQ4 A;  4FMW A;  3IEF A;  4H3Y A;  1VH0 A;  3N4K A;  3GYQ A;  4KGN A;  4YPY A;  3O7B A;  4L69 A;  1NS5 A;  3AXZ A;  4YQO A;  1RCS A;  2I6D A;  2Z0Y A;  1V2X A;  3AI9 X;  4CNE A;  4YPW A;  2EGW A;  4MCC A;  2O3A A;  4FAK A;  4YVK A;  4E8B A;  4YVJ A;  4YQ9 A;  4MCD A;  4CND A;  4JWG A;  4YVI A;  3SSX N;  4CNG A;  3OIN A;  5D9F A;  4YPX A;  4YQC A;  3SSW N;  1WRP R;  1ZT9 A;  4X3M A;  4IG6 A;  3KTY A;  1GZ0 A;  4YVH A;  2V3K A;  5CO4 A;  3KW2 A;  4KDZ A;  4YQB A;  2QWV A;  3IC6 A;  3OIJ A;  4YQA A;  5GM8 A;  2YY8 A;  4YQQ A;  3KOR A;  1X7P A;  3QUV A;  1X7O A;  1TRO A;  4YQI A;  1UAJ A;  1MI7 R;  3FRW A;  4JWH A;  1O6D A;  1WRS R;  4YPZ A;  3KY7 A;  1TRR A;  4RG1 A; 
#chains in the Genus database with same CATH homology
 1NXZ A;  3AIA A;  4YQN A;  3BBE A;  4YQ2 A;  4PZK A;  4YQP A;  4YQ1 A;  1TO0 A;  4YQ0 A;  2V3J A;  4CNF A;  3BBD A;  3E5Y A;  4XBO A;  4YQ5 A;  3BBH A;  1V6Z A;  1P9P A;  1UAM A;  1MXI A;  1K3R A;  3ILK A;  4YQR A;  4YQG A;  3KNU A;  4YQ6 A;  4YQT A;  4YQ3 A;  4JWJ A;  2CX8 A;  1Z85 A;  1VHY A;  4YQL A;  1OY5 A;  3DCM X;  1VHK A;  2QMM A;  4H3Z A;  3L8U A;  4JAL A;  4JAK A;  1IPA A;  3ONP A;  5FAI A;  5GMB A;  4YQK A;  5GMC A;  1ZJR A;  3OII A;  3N4J A;  4YQD A;  4YQ8 A;  4X3L A;  4MCB A;  2HA8 A;  2EGV A;  4JWF A;  4YQS A;  4YQ7 A;  3NK7 A;  1UAK A;  1J85 A;  4YVG A;  4YQJ A;  4J3C A;  3NK6 A;  1UAL A;  4YQ4 A;  4FMW A;  3IEF A;  4H3Y A;  1VH0 A;  3N4K A;  3GYQ A;  4KGN A;  4YPY A;  3O7B A;  4L69 A;  1NS5 A;  3AXZ A;  4YQO A;  2I6D A;  2Z0Y A;  1V2X A;  3AI9 X;  4CNE A;  4YPW A;  2EGW A;  4MCC A;  2O3A A;  4FAK A;  4YVK A;  4E8B A;  4YVJ A;  4YQ9 A;  4MCD A;  4CND A;  4JWG A;  4YVI A;  4CNG A;  3OIN A;  5D9F A;  4YPX A;  4YQC A;  4X3M A;  4IG6 A;  3KTY A;  1GZ0 A;  4YVH A;  2V3K A;  5CO4 A;  3KW2 A;  4KDZ A;  4YQB A;  2QWV A;  3IC6 A;  3OIJ A;  4YQA A;  5GM8 A;  2YY8 A;  4YQQ A;  1X7P A;  3QUV A;  1X7O A;  4YQI A;  1UAJ A;  4JWH A;  1O6D A;  4YPZ A;  3KY7 A;  4RG1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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