4YPZA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
248
structure length
236
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypzA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypzA01
5GM8A 3OINA 1UAMA 4YQ2A 1NS5A 4YQPA 1V6ZA 5GMCA 1OY5A 2I6DA 3AI9X 4MCBA 4YQNA 3BBHA 3NK7A 4YQQA 2QWVA 3IEFA 1TO0A 4JALA 2EGVA 3KY7A 4X3LA 1VH0A 4X3MA 4YPZA 3ONPA 4YPYA 3QUVA 5FAIA 4CNFA 3L8UA 4YQBA 3IC6A 4YQOA 5GMBA 1VHKA 4YQ9A 2QMMA 4YPWA 1UAKA 4KGNA 2Z0YA 4YQIA 2V3KA 4YQ5A 4YQRA 4YVHA 4YVKA 4H3ZA 1IPAA 3N4KA 3GYQA 3O7BA 1VHYA 4YQDA 3NK6A 4YQKA 4CNEA 5CO4A 4RG1A 4YPXA 4YQ3A 4YQCA 4YQSA 1Z85A 2HA8A 4YQJA 1K3RA 1GZ0A 1J85A 2YY8A 4YVJA 5D9FA 3KW2A 3BBEA 2O3AA 4YQLA 3KNUA 4L69A 3E5YA 2V3JA 1V2XA 4FAKA 3OIIA 4E8BA 4YQGA 1NXZA 4J3CA 4CNGA 1X7OA 4PZKA 2EGWA 4JAKA 3ILKA 3AIAA 4MCCA 4YQ0A 4IG6A 4YVIA 3BBDA 3N4JA 4YQ6A 1O6DA 4YQAA 4MCDA 4H3YA 2CX8A 4YQ4A 4YQ1A 1MXIA 3KTYA 1UALA 1P9PA 4CNDA 4YQ7A 1ZJRA 4XBOA 3DCMX 3AXZA 1UAJA 4YQ8A 3OIJA 1X7PA 4YVGA 4KDZA 4YQTA
chains in the Genus database with same CATH superfamily
3KORA 5GM8A 3OINA 1JHGA 1UAMA 4YQ2A 1NS5A 2XDIA 4YQPA 1V6ZA 5GMCA 1OY5A 2I6DA 3AI9X 4MCBA 4YQNA 3BBHA 3NK7A 4YQQA 2QWVA 3IEFA 3G1CA 1TO0A 4JALA 2EGVA 3KY7A 4X3LA 1VH0A 4X3MA 4YPZA 3ONPA 4YPYA 3QUVA 5FAIA 4CNFA 3L8UA 4YQBA 3IC6A 1ZT9A 4YQOA 5GMBA 1CO0A 3FRWA 1VHKA 4YQ9A 2QMMA 1RCSA 4YPWA 1UAKA 4KGNA 2Z0YA 4YQIA 2V3KA 2OZ9R 4YQRA 1TROA 4YVHA 4YVKA 4H3ZA 1IPAA 3N4KA 3GYQA 3O7BA 4FMWA 1VHYA 4YQDA 3NK6A 4YQKA 4CNEA 5CO4A 4RG1A 4JWJA 4JWFA 4YPXA 4YQ3A 3WRPA 4YQCA 4YQSA 1Z85A 2HA8A 4YQJA 1MI7R 1K3RA 1GZ0A 1J85A 2YY8A 4YVJA 5D9FA 3KW2A 3BBEA 2O3AA 1WRPR 1WRSR 4YQLA 3KNUA 4L69A 3E5YA 2V3JA 1V2XA 3SSWN 4FAKA 3OIIA 4E8BA 1WRTR 1X7PA 4YQGA 1NXZA 4J3CA 4CNGA 1X7OA 4PZKA 4JWHA 3SSXN 2EGWA 4JAKA 3ILKA 3AIAA 4MCCA 4YQ0A 4IG6A 4YVIA 3BBDA 3N4JA 4YQ6A 1O6DA 4YQAA 4MCDA 4H3YA 2CX8A 4YQ4A 4YQ1A 1MXIA 3KTYA 1UALA 1P9PA 1TRRA 4CNDA 4YQ7A 1ZJRA 4JWGA 4XBOA 3DCMX 3AXZA 1UAJA 4YQ8A 3OIJA 4YQ5A 4YVGA 4KDZA 4YQTA
chains in the Genus database with same CATH topology
5GM8A 3OINA 1UAMA 4YQ2A 1NS5A 4YQPA 1V6ZA 5GMCA 1OY5A 2I6DA 3AI9X 4MCBA 4YQNA 3BBHA 3NK7A 4YQQA 2QWVA 3IEFA 1TO0A 4JALA 2EGVA 3KY7A 4X3LA 1VH0A 4X3MA 4YPZA 3ONPA 4YPYA 3QUVA 5FAIA 4CNFA 3L8UA 4YQBA 3IC6A 4YQOA 5GMBA 1VHKA 4YQ9A 2QMMA 4YPWA 1UAKA 4KGNA 2Z0YA 4YQIA 2V3KA 4YQ5A 4YQRA 4YVHA 4YVKA 4H3ZA 1IPAA 3N4KA 3GYQA 3O7BA 4FMWA 1VHYA 4YQDA 3NK6A 4YQKA 4CNEA 5CO4A 4RG1A 4JWJA 4JWFA 4YPXA 4YQ3A 4YQCA 4YQSA 1Z85A 2HA8A 4YQJA 1K3RA 1GZ0A 1J85A 2YY8A 4YVJA 5D9FA 3KW2A 3BBEA 2O3AA 4YQLA 3KNUA 4L69A 3E5YA 2V3JA 1V2XA 4FAKA 3OIIA 4E8BA 4YQGA 1NXZA 4J3CA 4CNGA 1X7OA 4PZKA 4JWHA 2EGWA 4JAKA 3ILKA 3AIAA 4MCCA 4YQ0A 4IG6A 4YVIA 3BBDA 3N4JA 4YQ6A 1O6DA 4YQAA 4MCDA 4H3YA 2CX8A 4YQ4A 4YQ1A 1MXIA 3KTYA 1UALA 1P9PA 4CNDA 4YQ7A 1ZJRA 4JWGA 4XBOA 3DCMX 3AXZA 1UAJA 4YQ8A 3OIJA 1X7PA 4YVGA 4KDZA 4YQTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GM8 A;  3OIN A;  1UAM A;  4YQ2 A;  1NS5 A;  4YQP A;  1V6Z A;  5GMC A;  1OY5 A;  2I6D A;  3AI9 X;  4MCB A;  4YQN A;  3BBH A;  3NK7 A;  4YQQ A;  2QWV A;  3IEF A;  1TO0 A;  4JAL A;  2EGV A;  3KY7 A;  4X3L A;  1VH0 A;  4X3M A;  4YPZ A;  3ONP A;  4YPY A;  3QUV A;  5FAI A;  4CNF A;  3L8U A;  4YQB A;  3IC6 A;  4YQO A;  5GMB A;  1VHK A;  4YQ9 A;  2QMM A;  4YPW A;  1UAK A;  4KGN A;  2Z0Y A;  4YQI A;  2V3K A;  4YQ5 A;  4YQR A;  4YVH A;  4YVK A;  4H3Z A;  1IPA A;  3N4K A;  3GYQ A;  3O7B A;  1VHY A;  4YQD A;  3NK6 A;  4YQK A;  4CNE A;  5CO4 A;  4RG1 A;  4YPX A;  4YQ3 A;  4YQC A;  4YQS A;  1Z85 A;  2HA8 A;  4YQJ A;  1K3R A;  1GZ0 A;  1J85 A;  2YY8 A;  4YVJ A;  5D9F A;  3KW2 A;  3BBE A;  2O3A A;  4YQL A;  3KNU A;  4L69 A;  3E5Y A;  2V3J A;  1V2X A;  4FAK A;  3OII A;  4E8B A;  4YQG A;  1NXZ A;  4J3C A;  4CNG A;  1X7O A;  4PZK A;  2EGW A;  4JAK A;  3ILK A;  3AIA A;  4MCC A;  4YQ0 A;  4IG6 A;  4YVI A;  3BBD A;  3N4J A;  4YQ6 A;  1O6D A;  4YQA A;  4MCD A;  4H3Y A;  2CX8 A;  4YQ4 A;  4YQ1 A;  1MXI A;  3KTY A;  1UAL A;  1P9P A;  4CND A;  4YQ7 A;  1ZJR A;  4XBO A;  3DCM X;  3AXZ A;  1UAJ A;  4YQ8 A;  3OIJ A;  1X7P A;  4YVG A;  4KDZ A;  4YQT A; 
#chains in the Genus database with same CATH topology
 3KOR A;  5GM8 A;  3OIN A;  1JHG A;  1UAM A;  4YQ2 A;  1NS5 A;  2XDI A;  4YQP A;  1V6Z A;  5GMC A;  1OY5 A;  2I6D A;  3AI9 X;  4MCB A;  4YQN A;  3BBH A;  3NK7 A;  4YQQ A;  2QWV A;  3IEF A;  3G1C A;  1TO0 A;  4JAL A;  2EGV A;  3KY7 A;  4X3L A;  1VH0 A;  4X3M A;  4YPZ A;  3ONP A;  4YPY A;  3QUV A;  5FAI A;  4CNF A;  3L8U A;  4YQB A;  3IC6 A;  1ZT9 A;  4YQO A;  5GMB A;  1CO0 A;  3FRW A;  1VHK A;  4YQ9 A;  2QMM A;  1RCS A;  4YPW A;  1UAK A;  4KGN A;  2Z0Y A;  4YQI A;  2V3K A;  2OZ9 R;  4YQR A;  1TRO A;  4YVH A;  4YVK A;  4H3Z A;  1IPA A;  3N4K A;  3GYQ A;  3O7B A;  4FMW A;  1VHY A;  4YQD A;  3NK6 A;  4YQK A;  4CNE A;  5CO4 A;  4RG1 A;  4JWJ A;  4JWF A;  4YPX A;  4YQ3 A;  3WRP A;  4YQC A;  4YQS A;  1Z85 A;  2HA8 A;  4YQJ A;  1MI7 R;  1K3R A;  1GZ0 A;  1J85 A;  2YY8 A;  4YVJ A;  5D9F A;  3KW2 A;  3BBE A;  2O3A A;  1WRP R;  1WRS R;  4YQL A;  3KNU A;  4L69 A;  3E5Y A;  2V3J A;  1V2X A;  3SSW N;  4FAK A;  3OII A;  4E8B A;  1WRT R;  1X7P A;  4YQG A;  1NXZ A;  4J3C A;  4CNG A;  1X7O A;  4PZK A;  4JWH A;  3SSX N;  2EGW A;  4JAK A;  3ILK A;  3AIA A;  4MCC A;  4YQ0 A;  4IG6 A;  4YVI A;  3BBD A;  3N4J A;  4YQ6 A;  1O6D A;  4YQA A;  4MCD A;  4H3Y A;  2CX8 A;  4YQ4 A;  4YQ1 A;  1MXI A;  3KTY A;  1UAL A;  1P9P A;  1TRR A;  4CND A;  4YQ7 A;  1ZJR A;  4JWG A;  4XBO A;  3DCM X;  3AXZ A;  1UAJ A;  4YQ8 A;  3OIJ A;  4YQ5 A;  4YVG A;  4KDZ A;  4YQT A; 
#chains in the Genus database with same CATH homology
 5GM8 A;  3OIN A;  1UAM A;  4YQ2 A;  1NS5 A;  4YQP A;  1V6Z A;  5GMC A;  1OY5 A;  2I6D A;  3AI9 X;  4MCB A;  4YQN A;  3BBH A;  3NK7 A;  4YQQ A;  2QWV A;  3IEF A;  1TO0 A;  4JAL A;  2EGV A;  3KY7 A;  4X3L A;  1VH0 A;  4X3M A;  4YPZ A;  3ONP A;  4YPY A;  3QUV A;  5FAI A;  4CNF A;  3L8U A;  4YQB A;  3IC6 A;  4YQO A;  5GMB A;  1VHK A;  4YQ9 A;  2QMM A;  4YPW A;  1UAK A;  4KGN A;  2Z0Y A;  4YQI A;  2V3K A;  4YQ5 A;  4YQR A;  4YVH A;  4YVK A;  4H3Z A;  1IPA A;  3N4K A;  3GYQ A;  3O7B A;  4FMW A;  1VHY A;  4YQD A;  3NK6 A;  4YQK A;  4CNE A;  5CO4 A;  4RG1 A;  4JWJ A;  4JWF A;  4YPX A;  4YQ3 A;  4YQC A;  4YQS A;  1Z85 A;  2HA8 A;  4YQJ A;  1K3R A;  1GZ0 A;  1J85 A;  2YY8 A;  4YVJ A;  5D9F A;  3KW2 A;  3BBE A;  2O3A A;  4YQL A;  3KNU A;  4L69 A;  3E5Y A;  2V3J A;  1V2X A;  4FAK A;  3OII A;  4E8B A;  4YQG A;  1NXZ A;  4J3C A;  4CNG A;  1X7O A;  4PZK A;  4JWH A;  2EGW A;  4JAK A;  3ILK A;  3AIA A;  4MCC A;  4YQ0 A;  4IG6 A;  4YVI A;  3BBD A;  3N4J A;  4YQ6 A;  1O6D A;  4YQA A;  4MCD A;  4H3Y A;  2CX8 A;  4YQ4 A;  4YQ1 A;  1MXI A;  3KTY A;  1UAL A;  1P9P A;  4CND A;  4YQ7 A;  1ZJR A;  4JWG A;  4XBO A;  3DCM X;  3AXZ A;  1UAJ A;  4YQ8 A;  3OIJ A;  1X7P A;  4YVG A;  4KDZ A;  4YQT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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