4YQ0A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 73
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq0A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq0A01
4YPWA 4YQ8A 1VHYA 3ILKA 3AXZA 4L69A 4YVHA 4YQ7A 4YQJA 1MXIA 2O3AA 3O7BA 3NK7A 4FAKA 2EGVA 3OIJA 1OY5A 3DCMX 4YVGA 4YQKA 4YQ5A 4YQTA 3IC6A 1IPAA 4YQPA 4YQCA 4YQ4A 2HA8A 4YQ3A 3BBDA 3N4KA 4YVKA 3N4JA 4YQ2A 3OINA 4YQ6A 1J85A 4J3CA 4X3LA 4YQAA 1NXZA 3BBHA 5GMCA 3L8UA 1UAJA 4MCCA 4CNDA 4YQLA 4YQGA 3BBEA 1UALA 1K3RA 1TO0A 1VH0A 1UAMA 4IG6A 1GZ0A 4MCDA 4YQNA 3GYQA 4YPXA 2I6DA 4YQIA 1O6DA 1UAKA 1V6ZA 4CNFA 4YQRA 1X7PA 5FAIA 3AI9X 2Z0YA 5CO4A 4JALA 3ONPA 3NK6A 1NS5A 4YPZA 4YVIA 4JAKA 4YQDA 4YVJA 4KGNA 4XBOA 2CX8A 3QUVA 3IEFA 5GM8A 4YQ1A 1X7OA 1V2XA 4H3ZA 5GMBA 4X3MA 4E8BA 4YQOA 3OIIA 1VHKA 2V3KA 3KNUA 4RG1A 4YQ9A 4CNGA 3KW2A 2QMMA 3E5YA 2EGWA 3KY7A 4KDZA 4YQSA 2YY8A 4YQQA 2V3JA 1Z85A 3KTYA 4YQ0A 4H3YA 1ZJRA 3AIAA 4PZKA 2QWVA 4MCBA 4YQBA 5D9FA 4CNEA 1P9PA 4YPYA
chains in the Genus database with same CATH superfamily
3WRPA 4YPWA 4YQ8A 1VHYA 3ILKA 3AXZA 4L69A 1ZT9A 4YVHA 4YQ7A 1TRRA 4YQJA 1MXIA 2O3AA 3O7BA 2XDIA 3NK7A 4FAKA 2EGVA 3OIJA 1OY5A 3DCMX 4YVGA 4YQKA 3SSWN 4JWGA 4YQ5A 4YQTA 3IC6A 1IPAA 4YQPA 4YQCA 4YQ4A 2HA8A 4YQ3A 3BBDA 4FMWA 3N4KA 4JWJA 4YVKA 3N4JA 1MI7R 4YQ2A 3OINA 4YQ6A 1J85A 4J3CA 4X3LA 4YQAA 1NXZA 3BBHA 5GMCA 1JHGA 1UAJA 4MCCA 3L8UA 4CNDA 1RCSA 1WRTR 4YQLA 4YQGA 1CO0A 3BBEA 1UALA 1K3RA 3G1CA 1TO0A 1VH0A 1UAMA 4IG6A 1GZ0A 4JWHA 4MCDA 4YQNA 3GYQA 4YPXA 2I6DA 4YQIA 1O6DA 1UAKA 1V6ZA 4CNFA 1WRSR 4YQRA 1X7PA 5FAIA 3AI9X 2Z0YA 5CO4A 4JALA 3ONPA 3NK6A 1NS5A 4YPZA 4YVIA 4JAKA 4YQDA 4YVJA 4KGNA 4XBOA 2CX8A 3IEFA 3QUVA 3SSXN 5GM8A 4YQ1A 1X7OA 1V2XA 4H3ZA 3KORA 5GMBA 1TROA 4X3MA 2OZ9R 4E8BA 4YQOA 3OIIA 1VHKA 2V3KA 3KNUA 4RG1A 4YQ9A 4CNGA 3KW2A 2QMMA 1WRPR 3E5YA 2EGWA 3KY7A 4KDZA 4YQSA 2YY8A 4YQQA 2V3JA 1Z85A 3KTYA 4YQ0A 4H3YA 1ZJRA 3FRWA 3AIAA 4PZKA 4JWFA 2QWVA 4MCBA 4YQBA 5D9FA 4CNEA 1P9PA 4YPYA
chains in the Genus database with same CATH topology
4YPWA 4YQ8A 1VHYA 3ILKA 3AXZA 4L69A 4YVHA 4YQ7A 4YQJA 1MXIA 2O3AA 3O7BA 3NK7A 4FAKA 2EGVA 3OIJA 1OY5A 3DCMX 4YVGA 4YQKA 4JWGA 4YQ5A 4YQTA 3IC6A 1IPAA 4YQPA 4YQCA 4YQ4A 2HA8A 4YQ3A 3BBDA 4FMWA 3N4KA 4JWJA 4YVKA 3N4JA 4YQ2A 3OINA 4YQ6A 1J85A 4J3CA 4X3LA 4YQAA 1NXZA 3BBHA 5GMCA 3L8UA 1UAJA 4MCCA 4CNDA 4YQLA 4YQGA 3BBEA 1UALA 1K3RA 1TO0A 1VH0A 1UAMA 4IG6A 1GZ0A 4JWHA 4MCDA 4YQNA 3GYQA 4YPXA 2I6DA 4YQIA 1O6DA 1UAKA 1V6ZA 4CNFA 4YQRA 1X7PA 5FAIA 3AI9X 2Z0YA 5CO4A 4JALA 3ONPA 3NK6A 1NS5A 4YPZA 4YVIA 4JAKA 4YQDA 4YVJA 4KGNA 4XBOA 2CX8A 3QUVA 3IEFA 5GM8A 4YQ1A 1X7OA 1V2XA 4H3ZA 5GMBA 4X3MA 4E8BA 4YQOA 3OIIA 1VHKA 2V3KA 3KNUA 4RG1A 4YQ9A 4CNGA 3KW2A 2QMMA 3E5YA 2EGWA 3KY7A 4KDZA 4YQSA 2YY8A 4YQQA 2V3JA 1Z85A 3KTYA 4YQ0A 4H3YA 1ZJRA 3AIAA 4PZKA 4JWFA 2QWVA 4MCBA 4YQBA 5D9FA 4CNEA 1P9PA 4YPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPW A;  4YQ8 A;  1VHY A;  3ILK A;  3AXZ A;  4L69 A;  4YVH A;  4YQ7 A;  4YQJ A;  1MXI A;  2O3A A;  3O7B A;  3NK7 A;  4FAK A;  2EGV A;  3OIJ A;  1OY5 A;  3DCM X;  4YVG A;  4YQK A;  4YQ5 A;  4YQT A;  3IC6 A;  1IPA A;  4YQP A;  4YQC A;  4YQ4 A;  2HA8 A;  4YQ3 A;  3BBD A;  3N4K A;  4YVK A;  3N4J A;  4YQ2 A;  3OIN A;  4YQ6 A;  1J85 A;  4J3C A;  4X3L A;  4YQA A;  1NXZ A;  3BBH A;  5GMC A;  3L8U A;  1UAJ A;  4MCC A;  4CND A;  4YQL A;  4YQG A;  3BBE A;  1UAL A;  1K3R A;  1TO0 A;  1VH0 A;  1UAM A;  4IG6 A;  1GZ0 A;  4MCD A;  4YQN A;  3GYQ A;  4YPX A;  2I6D A;  4YQI A;  1O6D A;  1UAK A;  1V6Z A;  4CNF A;  4YQR A;  1X7P A;  5FAI A;  3AI9 X;  2Z0Y A;  5CO4 A;  4JAL A;  3ONP A;  3NK6 A;  1NS5 A;  4YPZ A;  4YVI A;  4JAK A;  4YQD A;  4YVJ A;  4KGN A;  4XBO A;  2CX8 A;  3QUV A;  3IEF A;  5GM8 A;  4YQ1 A;  1X7O A;  1V2X A;  4H3Z A;  5GMB A;  4X3M A;  4E8B A;  4YQO A;  3OII A;  1VHK A;  2V3K A;  3KNU A;  4RG1 A;  4YQ9 A;  4CNG A;  3KW2 A;  2QMM A;  3E5Y A;  2EGW A;  3KY7 A;  4KDZ A;  4YQS A;  2YY8 A;  4YQQ A;  2V3J A;  1Z85 A;  3KTY A;  4YQ0 A;  4H3Y A;  1ZJR A;  3AIA A;  4PZK A;  2QWV A;  4MCB A;  4YQB A;  5D9F A;  4CNE A;  1P9P A;  4YPY A; 
#chains in the Genus database with same CATH topology
 3WRP A;  4YPW A;  4YQ8 A;  1VHY A;  3ILK A;  3AXZ A;  4L69 A;  1ZT9 A;  4YVH A;  4YQ7 A;  1TRR A;  4YQJ A;  1MXI A;  2O3A A;  3O7B A;  2XDI A;  3NK7 A;  4FAK A;  2EGV A;  3OIJ A;  1OY5 A;  3DCM X;  4YVG A;  4YQK A;  3SSW N;  4JWG A;  4YQ5 A;  4YQT A;  3IC6 A;  1IPA A;  4YQP A;  4YQC A;  4YQ4 A;  2HA8 A;  4YQ3 A;  3BBD A;  4FMW A;  3N4K A;  4JWJ A;  4YVK A;  3N4J A;  1MI7 R;  4YQ2 A;  3OIN A;  4YQ6 A;  1J85 A;  4J3C A;  4X3L A;  4YQA A;  1NXZ A;  3BBH A;  5GMC A;  1JHG A;  1UAJ A;  4MCC A;  3L8U A;  4CND A;  1RCS A;  1WRT R;  4YQL A;  4YQG A;  1CO0 A;  3BBE A;  1UAL A;  1K3R A;  3G1C A;  1TO0 A;  1VH0 A;  1UAM A;  4IG6 A;  1GZ0 A;  4JWH A;  4MCD A;  4YQN A;  3GYQ A;  4YPX A;  2I6D A;  4YQI A;  1O6D A;  1UAK A;  1V6Z A;  4CNF A;  1WRS R;  4YQR A;  1X7P A;  5FAI A;  3AI9 X;  2Z0Y A;  5CO4 A;  4JAL A;  3ONP A;  3NK6 A;  1NS5 A;  4YPZ A;  4YVI A;  4JAK A;  4YQD A;  4YVJ A;  4KGN A;  4XBO A;  2CX8 A;  3IEF A;  3QUV A;  3SSX N;  5GM8 A;  4YQ1 A;  1X7O A;  1V2X A;  4H3Z A;  3KOR A;  5GMB A;  1TRO A;  4X3M A;  2OZ9 R;  4E8B A;  4YQO A;  3OII A;  1VHK A;  2V3K A;  3KNU A;  4RG1 A;  4YQ9 A;  4CNG A;  3KW2 A;  2QMM A;  1WRP R;  3E5Y A;  2EGW A;  3KY7 A;  4KDZ A;  4YQS A;  2YY8 A;  4YQQ A;  2V3J A;  1Z85 A;  3KTY A;  4YQ0 A;  4H3Y A;  1ZJR A;  3FRW A;  3AIA A;  4PZK A;  4JWF A;  2QWV A;  4MCB A;  4YQB A;  5D9F A;  4CNE A;  1P9P A;  4YPY A; 
#chains in the Genus database with same CATH homology
 4YPW A;  4YQ8 A;  1VHY A;  3ILK A;  3AXZ A;  4L69 A;  4YVH A;  4YQ7 A;  4YQJ A;  1MXI A;  2O3A A;  3O7B A;  3NK7 A;  4FAK A;  2EGV A;  3OIJ A;  1OY5 A;  3DCM X;  4YVG A;  4YQK A;  4JWG A;  4YQ5 A;  4YQT A;  3IC6 A;  1IPA A;  4YQP A;  4YQC A;  4YQ4 A;  2HA8 A;  4YQ3 A;  3BBD A;  4FMW A;  3N4K A;  4JWJ A;  4YVK A;  3N4J A;  4YQ2 A;  3OIN A;  4YQ6 A;  1J85 A;  4J3C A;  4X3L A;  4YQA A;  1NXZ A;  3BBH A;  5GMC A;  3L8U A;  1UAJ A;  4MCC A;  4CND A;  4YQL A;  4YQG A;  3BBE A;  1UAL A;  1K3R A;  1TO0 A;  1VH0 A;  1UAM A;  4IG6 A;  1GZ0 A;  4JWH A;  4MCD A;  4YQN A;  3GYQ A;  4YPX A;  2I6D A;  4YQI A;  1O6D A;  1UAK A;  1V6Z A;  4CNF A;  4YQR A;  1X7P A;  5FAI A;  3AI9 X;  2Z0Y A;  5CO4 A;  4JAL A;  3ONP A;  3NK6 A;  1NS5 A;  4YPZ A;  4YVI A;  4JAK A;  4YQD A;  4YVJ A;  4KGN A;  4XBO A;  2CX8 A;  3QUV A;  3IEF A;  5GM8 A;  4YQ1 A;  1X7O A;  1V2X A;  4H3Z A;  5GMB A;  4X3M A;  4E8B A;  4YQO A;  3OII A;  1VHK A;  2V3K A;  3KNU A;  4RG1 A;  4YQ9 A;  4CNG A;  3KW2 A;  2QMM A;  3E5Y A;  2EGW A;  3KY7 A;  4KDZ A;  4YQS A;  2YY8 A;  4YQQ A;  2V3J A;  1Z85 A;  3KTY A;  4YQ0 A;  4H3Y A;  1ZJR A;  3AIA A;  4PZK A;  4JWF A;  2QWV A;  4MCB A;  4YQB A;  5D9F A;  4CNE A;  1P9P A;  4YPY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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