4YQ2A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
248
structure length
236
Chain Sequence
RGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 67
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq2A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq2A01
4CNGA 2QMMA 1IPAA 5GMCA 1NXZA 4YQ5A 1NS5A 4YQ6A 2EGVA 4YQBA 1X7PA 4YQ2A 4YQTA 4RG1A 3KTYA 3ONPA 5D9FA 3BBHA 4KGNA 4YQ1A 2Z0YA 1O6DA 3KNUA 4YQQA 1UALA 3AXZA 2EGWA 4MCBA 2O3AA 4YQJA 3BBEA 4IG6A 4X3LA 3BBDA 3N4KA 4MCCA 2YY8A 3OIJA 2CX8A 3NK6A 1UAMA 1X7OA 1K3RA 4J3CA 4YVJA 1TO0A 1VHKA 4YVGA 3IEFA 5GMBA 3NK7A 1OY5A 4YPXA 4YPYA 4YQSA 3QUVA 3AI9X 4KDZA 3L8UA 1UAJA 3O7BA 4YQ8A 4YQPA 4YVKA 3OIIA 4YQLA 3KY7A 4YQ4A 4E8BA 2QWVA 4YQ3A 3KW2A 2HA8A 4YQGA 3DCMX 4JALA 3IC6A 4H3ZA 1GZ0A 1UAKA 1V2XA 4MCDA 4YQAA 4YQCA 4YQDA 4YQ0A 4X3MA 2I6DA 4H3YA 1MXIA 5CO4A 4YQIA 3OINA 3E5YA 1P9PA 4YQRA 1J85A 4YQNA 4XBOA 4YQ7A 2V3KA 1VH0A 1VHYA 4YQKA 4CNDA 4YQOA 5GM8A 4YPWA 1V6ZA 4YVHA 4FAKA 4CNFA 3ILKA 3GYQA 2V3JA 4YQ9A 5FAIA 4L69A 4JAKA 1Z85A 4YVIA 3AIAA 3N4JA 4YPZA 4PZKA 1ZJRA 4CNEA
chains in the Genus database with same CATH superfamily
4CNGA 2QMMA 1IPAA 5GMCA 1MI7R 1NXZA 4YQ5A 4JWFA 1NS5A 4YQ6A 2EGVA 4YQBA 1X7PA 4YQ2A 4YQTA 4RG1A 2XDIA 1TRRA 3KTYA 3ONPA 5D9FA 3BBHA 4KGNA 4YQ1A 2Z0YA 1O6DA 3KNUA 4YQQA 1UALA 3AXZA 2EGWA 4MCBA 2O3AA 3WRPA 1WRSR 4YQJA 3BBEA 4IG6A 4X3LA 3BBDA 3G1CA 3N4KA 4MCCA 2YY8A 3OIJA 2CX8A 3NK6A 1UAMA 1X7OA 1K3RA 4J3CA 4JWJA 4YVJA 1TO0A 1VHKA 3IEFA 4YVGA 5GMBA 3NK7A 1OY5A 1TROA 1JHGA 4YPXA 4YPYA 4YQSA 3QUVA 3AI9X 4KDZA 3L8UA 1UAJA 3O7BA 4YQ8A 4YQPA 4YVKA 3OIIA 4YQLA 3KY7A 4YQ4A 4E8BA 2QWVA 4YQ3A 3KW2A 2HA8A 4YQGA 3DCMX 4JALA 3IC6A 4H3ZA 1GZ0A 1UAKA 3KORA 1V2XA 4JWGA 3FRWA 4MCDA 4YQAA 1RCSA 4YQCA 3SSXN 4YQDA 4YQ0A 4X3MA 2I6DA 4H3YA 1MXIA 5CO4A 4YQIA 4JWHA 3OINA 3E5YA 1P9PA 4YQRA 1J85A 1WRTR 3SSWN 4YQNA 4XBOA 1WRPR 4YQ7A 2V3KA 1VH0A 1VHYA 4FMWA 4YQKA 1CO0A 4CNDA 4YQOA 5GM8A 4YPWA 1V6ZA 4YVHA 4FAKA 4CNFA 3ILKA 2OZ9R 3GYQA 2V3JA 4YQ9A 5FAIA 4L69A 4JAKA 1Z85A 4YVIA 3AIAA 3N4JA 1ZT9A 4YPZA 4PZKA 1ZJRA 4CNEA
chains in the Genus database with same CATH topology
4CNGA 2QMMA 1IPAA 5GMCA 1NXZA 4YQ5A 4JWFA 1NS5A 4YQ6A 2EGVA 4YQBA 1X7PA 4YQ2A 4YQTA 4RG1A 3KTYA 3ONPA 5D9FA 3BBHA 4KGNA 4YQ1A 2Z0YA 1O6DA 3KNUA 4YQQA 1UALA 3AXZA 2EGWA 4MCBA 2O3AA 4YQJA 3BBEA 4IG6A 4X3LA 3BBDA 3N4KA 4MCCA 2YY8A 3OIJA 2CX8A 3NK6A 1UAMA 1X7OA 1K3RA 4J3CA 4JWJA 4YVJA 1TO0A 1VHKA 4YVGA 3IEFA 5GMBA 3NK7A 1OY5A 4YPXA 4YPYA 4YQSA 3QUVA 3AI9X 4KDZA 3L8UA 1UAJA 3O7BA 4YQ8A 4YQPA 4YVKA 3OIIA 4YQLA 3KY7A 4YQ4A 4E8BA 2QWVA 4YQ3A 3KW2A 2HA8A 4YQGA 3DCMX 4JALA 3IC6A 4H3ZA 1GZ0A 1UAKA 1V2XA 4JWGA 4MCDA 4YQAA 4YQCA 4YQDA 4YQ0A 4X3MA 2I6DA 4H3YA 1MXIA 5CO4A 4YQIA 4JWHA 3OINA 3E5YA 1P9PA 4YQRA 1J85A 4YQNA 4XBOA 4YQ7A 2V3KA 1VH0A 1VHYA 4FMWA 4YQKA 4CNDA 4YQOA 5GM8A 4YPWA 1V6ZA 4YVHA 4FAKA 4CNFA 3ILKA 3GYQA 2V3JA 4YQ9A 5FAIA 4L69A 4JAKA 1Z85A 4YVIA 3AIAA 3N4JA 4YPZA 4PZKA 1ZJRA 4CNEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CNG A;  2QMM A;  1IPA A;  5GMC A;  1NXZ A;  4YQ5 A;  1NS5 A;  4YQ6 A;  2EGV A;  4YQB A;  1X7P A;  4YQ2 A;  4YQT A;  4RG1 A;  3KTY A;  3ONP A;  5D9F A;  3BBH A;  4KGN A;  4YQ1 A;  2Z0Y A;  1O6D A;  3KNU A;  4YQQ A;  1UAL A;  3AXZ A;  2EGW A;  4MCB A;  2O3A A;  4YQJ A;  3BBE A;  4IG6 A;  4X3L A;  3BBD A;  3N4K A;  4MCC A;  2YY8 A;  3OIJ A;  2CX8 A;  3NK6 A;  1UAM A;  1X7O A;  1K3R A;  4J3C A;  4YVJ A;  1TO0 A;  1VHK A;  4YVG A;  3IEF A;  5GMB A;  3NK7 A;  1OY5 A;  4YPX A;  4YPY A;  4YQS A;  3QUV A;  3AI9 X;  4KDZ A;  3L8U A;  1UAJ A;  3O7B A;  4YQ8 A;  4YQP A;  4YVK A;  3OII A;  4YQL A;  3KY7 A;  4YQ4 A;  4E8B A;  2QWV A;  4YQ3 A;  3KW2 A;  2HA8 A;  4YQG A;  3DCM X;  4JAL A;  3IC6 A;  4H3Z A;  1GZ0 A;  1UAK A;  1V2X A;  4MCD A;  4YQA A;  4YQC A;  4YQD A;  4YQ0 A;  4X3M A;  2I6D A;  4H3Y A;  1MXI A;  5CO4 A;  4YQI A;  3OIN A;  3E5Y A;  1P9P A;  4YQR A;  1J85 A;  4YQN A;  4XBO A;  4YQ7 A;  2V3K A;  1VH0 A;  1VHY A;  4YQK A;  4CND A;  4YQO A;  5GM8 A;  4YPW A;  1V6Z A;  4YVH A;  4FAK A;  4CNF A;  3ILK A;  3GYQ A;  2V3J A;  4YQ9 A;  5FAI A;  4L69 A;  4JAK A;  1Z85 A;  4YVI A;  3AIA A;  3N4J A;  4YPZ A;  4PZK A;  1ZJR A;  4CNE A; 
#chains in the Genus database with same CATH topology
 4CNG A;  2QMM A;  1IPA A;  5GMC A;  1MI7 R;  1NXZ A;  4YQ5 A;  4JWF A;  1NS5 A;  4YQ6 A;  2EGV A;  4YQB A;  1X7P A;  4YQ2 A;  4YQT A;  4RG1 A;  2XDI A;  1TRR A;  3KTY A;  3ONP A;  5D9F A;  3BBH A;  4KGN A;  4YQ1 A;  2Z0Y A;  1O6D A;  3KNU A;  4YQQ A;  1UAL A;  3AXZ A;  2EGW A;  4MCB A;  2O3A A;  3WRP A;  1WRS R;  4YQJ A;  3BBE A;  4IG6 A;  4X3L A;  3BBD A;  3G1C A;  3N4K A;  4MCC A;  2YY8 A;  3OIJ A;  2CX8 A;  3NK6 A;  1UAM A;  1X7O A;  1K3R A;  4J3C A;  4JWJ A;  4YVJ A;  1TO0 A;  1VHK A;  3IEF A;  4YVG A;  5GMB A;  3NK7 A;  1OY5 A;  1TRO A;  1JHG A;  4YPX A;  4YPY A;  4YQS A;  3QUV A;  3AI9 X;  4KDZ A;  3L8U A;  1UAJ A;  3O7B A;  4YQ8 A;  4YQP A;  4YVK A;  3OII A;  4YQL A;  3KY7 A;  4YQ4 A;  4E8B A;  2QWV A;  4YQ3 A;  3KW2 A;  2HA8 A;  4YQG A;  3DCM X;  4JAL A;  3IC6 A;  4H3Z A;  1GZ0 A;  1UAK A;  3KOR A;  1V2X A;  4JWG A;  3FRW A;  4MCD A;  4YQA A;  1RCS A;  4YQC A;  3SSX N;  4YQD A;  4YQ0 A;  4X3M A;  2I6D A;  4H3Y A;  1MXI A;  5CO4 A;  4YQI A;  4JWH A;  3OIN A;  3E5Y A;  1P9P A;  4YQR A;  1J85 A;  1WRT R;  3SSW N;  4YQN A;  4XBO A;  1WRP R;  4YQ7 A;  2V3K A;  1VH0 A;  1VHY A;  4FMW A;  4YQK A;  1CO0 A;  4CND A;  4YQO A;  5GM8 A;  4YPW A;  1V6Z A;  4YVH A;  4FAK A;  4CNF A;  3ILK A;  2OZ9 R;  3GYQ A;  2V3J A;  4YQ9 A;  5FAI A;  4L69 A;  4JAK A;  1Z85 A;  4YVI A;  3AIA A;  3N4J A;  1ZT9 A;  4YPZ A;  4PZK A;  1ZJR A;  4CNE A; 
#chains in the Genus database with same CATH homology
 4CNG A;  2QMM A;  1IPA A;  5GMC A;  1NXZ A;  4YQ5 A;  4JWF A;  1NS5 A;  4YQ6 A;  2EGV A;  4YQB A;  1X7P A;  4YQ2 A;  4YQT A;  4RG1 A;  3KTY A;  3ONP A;  5D9F A;  3BBH A;  4KGN A;  4YQ1 A;  2Z0Y A;  1O6D A;  3KNU A;  4YQQ A;  1UAL A;  3AXZ A;  2EGW A;  4MCB A;  2O3A A;  4YQJ A;  3BBE A;  4IG6 A;  4X3L A;  3BBD A;  3N4K A;  4MCC A;  2YY8 A;  3OIJ A;  2CX8 A;  3NK6 A;  1UAM A;  1X7O A;  1K3R A;  4J3C A;  4JWJ A;  4YVJ A;  1TO0 A;  1VHK A;  4YVG A;  3IEF A;  5GMB A;  3NK7 A;  1OY5 A;  4YPX A;  4YPY A;  4YQS A;  3QUV A;  3AI9 X;  4KDZ A;  3L8U A;  1UAJ A;  3O7B A;  4YQ8 A;  4YQP A;  4YVK A;  3OII A;  4YQL A;  3KY7 A;  4YQ4 A;  4E8B A;  2QWV A;  4YQ3 A;  3KW2 A;  2HA8 A;  4YQG A;  3DCM X;  4JAL A;  3IC6 A;  4H3Z A;  1GZ0 A;  1UAK A;  1V2X A;  4JWG A;  4MCD A;  4YQA A;  4YQC A;  4YQD A;  4YQ0 A;  4X3M A;  2I6D A;  4H3Y A;  1MXI A;  5CO4 A;  4YQI A;  4JWH A;  3OIN A;  3E5Y A;  1P9P A;  4YQR A;  1J85 A;  4YQN A;  4XBO A;  4YQ7 A;  2V3K A;  1VH0 A;  1VHY A;  4FMW A;  4YQK A;  4CND A;  4YQO A;  5GM8 A;  4YPW A;  1V6Z A;  4YVH A;  4FAK A;  4CNF A;  3ILK A;  3GYQ A;  2V3J A;  4YQ9 A;  5FAI A;  4L69 A;  4JAK A;  1Z85 A;  4YVI A;  3AIA A;  3N4J A;  4YPZ A;  4PZK A;  1ZJR A;  4CNE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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