4YQ2A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
248
structure length
236
Chain Sequence
RGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 67
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq2A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq2A01
1UAJA 4YQ7A 4YQNA 4YVJA 4H3ZA 4CNGA 4YPWA 4YQ4A 1IPAA 1X7OA 4YQ6A 4YQ2A 1VHKA 3NK7A 1Z85A 4YVGA 5D9FA 1P9PA 4J3CA 3OIJA 3QUVA 4YQCA 3AXZA 3DCMX 1UALA 1V2XA 4YQJA 3KNUA 4YQPA 2EGWA 2I6DA 5CO4A 1ZJRA 3AIAA 3AI9X 3ILKA 1UAKA 4IG6A 1K3RA 3ONPA 4MCBA 4KGNA 4H3YA 4JAKA 4YPYA 1VHYA 4YVHA 4YQDA 3L8UA 4CNDA 4YQBA 4YQ3A 4YQIA 2HA8A 1GZ0A 3KY7A 4FAKA 3GYQA 4YQAA 4PZKA 5GM8A 3E5YA 1OY5A 1TO0A 4RG1A 1J85A 1NXZA 4YVKA 3KTYA 4YQLA 2Z0YA 1V6ZA 4XBOA 3BBDA 3OINA 4E8BA 4X3MA 2V3KA 4YQ5A 3O7BA 4YQKA 5GMCA 4MCDA 4YQ0A 4X3LA 4MCCA 4KDZA 2QMMA 1NS5A 2CX8A 3KW2A 3N4JA 2V3JA 4L69A 3NK6A 3BBEA 4YQOA 4JALA 5GMBA 5FAIA 4YQTA 4YQ8A 4CNFA 3IC6A 4YQGA 4YVIA 4YQ1A 1VH0A 4YQ9A 1O6DA 3N4KA 4YQSA 4YQQA 2O3AA 4YQRA 3BBHA 4YPZA 3IEFA 4CNEA 4YPXA 1X7PA 2QWVA 2YY8A 2EGVA 1UAMA 1MXIA 3OIIA
chains in the Genus database with same CATH superfamily
1UAJA 4YQ7A 4YQNA 1CO0A 4YVJA 4H3ZA 4CNGA 4YPWA 4YQ4A 1IPAA 1X7OA 4YQ6A 4YQ2A 3SSWN 1VHKA 3NK7A 1Z85A 4FMWA 2XDIA 4YVGA 5D9FA 1JHGA 1P9PA 4JWFA 4J3CA 3OIJA 3QUVA 4YQCA 3AXZA 3DCMX 1UALA 1V2XA 4YQJA 3KNUA 4YQPA 2EGWA 4JWJA 1TRRA 2I6DA 5CO4A 1ZJRA 3AIAA 3AI9X 3ILKA 1WRTR 1UAKA 4IG6A 1WRSR 1K3RA 3G1CA 3ONPA 4MCBA 4KGNA 4H3YA 4JWGA 4JAKA 4YPYA 1VHYA 4YVHA 4YQDA 3L8UA 4CNDA 4YQBA 4YQ3A 4YQIA 1WRPR 2HA8A 1GZ0A 3KY7A 3KORA 4FAKA 3GYQA 4YQAA 4PZKA 5GM8A 3E5YA 1OY5A 1TO0A 4RG1A 1ZT9A 1J85A 1NXZA 4YVKA 3KTYA 4YQLA 2Z0YA 1V6ZA 4XBOA 3BBDA 3OINA 4E8BA 4JWHA 4X3MA 2V3KA 3FRWA 4YQ5A 3O7BA 4YQKA 5GMCA 4MCDA 4YQ0A 4X3LA 4MCCA 4KDZA 2QMMA 1NS5A 2CX8A 1TROA 3KW2A 3N4JA 2V3JA 4L69A 3NK6A 1RCSA 3BBEA 4YQOA 4JALA 5GMBA 5FAIA 4YQTA 4YQ8A 4CNFA 3IC6A 2OZ9R 4YQGA 1MI7R 4YVIA 4YQ1A 1VH0A 4YQ9A 1O6DA 3N4KA 4YQSA 4YQQA 2O3AA 4YQRA 3BBHA 4YPZA 3IEFA 4CNEA 4YPXA 1X7PA 2QWVA 3SSXN 3WRPA 2YY8A 2EGVA 1UAMA 1MXIA 3OIIA
chains in the Genus database with same CATH topology
1UAJA 4YQ7A 4YQNA 4YVJA 4H3ZA 4CNGA 4YPWA 4YQ4A 1IPAA 1X7OA 4YQ6A 4YQ2A 1VHKA 3NK7A 1Z85A 4FMWA 4YVGA 5D9FA 1P9PA 4JWFA 4J3CA 3OIJA 3QUVA 4YQCA 3AXZA 3DCMX 1UALA 1V2XA 4YQJA 3KNUA 4YQPA 2EGWA 4JWJA 2I6DA 5CO4A 1ZJRA 3AIAA 3AI9X 3ILKA 1UAKA 4IG6A 1K3RA 3ONPA 4MCBA 4KGNA 4H3YA 4JWGA 4JAKA 4YPYA 1VHYA 4YVHA 4YQDA 3L8UA 4CNDA 4YQBA 4YQ3A 4YQIA 2HA8A 1GZ0A 3KY7A 4FAKA 3GYQA 4YQAA 4PZKA 5GM8A 3E5YA 1OY5A 1TO0A 4RG1A 1J85A 1NXZA 4YVKA 3KTYA 4YQLA 2Z0YA 1V6ZA 4XBOA 3BBDA 3OINA 4E8BA 4JWHA 4X3MA 2V3KA 4YQ5A 3O7BA 4YQKA 5GMCA 4MCDA 4YQ0A 4X3LA 4MCCA 4KDZA 2QMMA 1NS5A 2CX8A 3KW2A 3N4JA 2V3JA 4L69A 3NK6A 3BBEA 4YQOA 4JALA 5GMBA 5FAIA 4YQTA 4YQ8A 4CNFA 3IC6A 4YQGA 4YVIA 4YQ1A 1VH0A 4YQ9A 1O6DA 3N4KA 4YQSA 4YQQA 2O3AA 4YQRA 3BBHA 4YPZA 3IEFA 4CNEA 4YPXA 1X7PA 2QWVA 2YY8A 2EGVA 1UAMA 1MXIA 3OIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UAJ A;  4YQ7 A;  4YQN A;  4YVJ A;  4H3Z A;  4CNG A;  4YPW A;  4YQ4 A;  1IPA A;  1X7O A;  4YQ6 A;  4YQ2 A;  1VHK A;  3NK7 A;  1Z85 A;  4YVG A;  5D9F A;  1P9P A;  4J3C A;  3OIJ A;  3QUV A;  4YQC A;  3AXZ A;  3DCM X;  1UAL A;  1V2X A;  4YQJ A;  3KNU A;  4YQP A;  2EGW A;  2I6D A;  5CO4 A;  1ZJR A;  3AIA A;  3AI9 X;  3ILK A;  1UAK A;  4IG6 A;  1K3R A;  3ONP A;  4MCB A;  4KGN A;  4H3Y A;  4JAK A;  4YPY A;  1VHY A;  4YVH A;  4YQD A;  3L8U A;  4CND A;  4YQB A;  4YQ3 A;  4YQI A;  2HA8 A;  1GZ0 A;  3KY7 A;  4FAK A;  3GYQ A;  4YQA A;  4PZK A;  5GM8 A;  3E5Y A;  1OY5 A;  1TO0 A;  4RG1 A;  1J85 A;  1NXZ A;  4YVK A;  3KTY A;  4YQL A;  2Z0Y A;  1V6Z A;  4XBO A;  3BBD A;  3OIN A;  4E8B A;  4X3M A;  2V3K A;  4YQ5 A;  3O7B A;  4YQK A;  5GMC A;  4MCD A;  4YQ0 A;  4X3L A;  4MCC A;  4KDZ A;  2QMM A;  1NS5 A;  2CX8 A;  3KW2 A;  3N4J A;  2V3J A;  4L69 A;  3NK6 A;  3BBE A;  4YQO A;  4JAL A;  5GMB A;  5FAI A;  4YQT A;  4YQ8 A;  4CNF A;  3IC6 A;  4YQG A;  4YVI A;  4YQ1 A;  1VH0 A;  4YQ9 A;  1O6D A;  3N4K A;  4YQS A;  4YQQ A;  2O3A A;  4YQR A;  3BBH A;  4YPZ A;  3IEF A;  4CNE A;  4YPX A;  1X7P A;  2QWV A;  2YY8 A;  2EGV A;  1UAM A;  1MXI A;  3OII A; 
#chains in the Genus database with same CATH topology
 1UAJ A;  4YQ7 A;  4YQN A;  1CO0 A;  4YVJ A;  4H3Z A;  4CNG A;  4YPW A;  4YQ4 A;  1IPA A;  1X7O A;  4YQ6 A;  4YQ2 A;  3SSW N;  1VHK A;  3NK7 A;  1Z85 A;  4FMW A;  2XDI A;  4YVG A;  5D9F A;  1JHG A;  1P9P A;  4JWF A;  4J3C A;  3OIJ A;  3QUV A;  4YQC A;  3AXZ A;  3DCM X;  1UAL A;  1V2X A;  4YQJ A;  3KNU A;  4YQP A;  2EGW A;  4JWJ A;  1TRR A;  2I6D A;  5CO4 A;  1ZJR A;  3AIA A;  3AI9 X;  3ILK A;  1WRT R;  1UAK A;  4IG6 A;  1WRS R;  1K3R A;  3G1C A;  3ONP A;  4MCB A;  4KGN A;  4H3Y A;  4JWG A;  4JAK A;  4YPY A;  1VHY A;  4YVH A;  4YQD A;  3L8U A;  4CND A;  4YQB A;  4YQ3 A;  4YQI A;  1WRP R;  2HA8 A;  1GZ0 A;  3KY7 A;  3KOR A;  4FAK A;  3GYQ A;  4YQA A;  4PZK A;  5GM8 A;  3E5Y A;  1OY5 A;  1TO0 A;  4RG1 A;  1ZT9 A;  1J85 A;  1NXZ A;  4YVK A;  3KTY A;  4YQL A;  2Z0Y A;  1V6Z A;  4XBO A;  3BBD A;  3OIN A;  4E8B A;  4JWH A;  4X3M A;  2V3K A;  3FRW A;  4YQ5 A;  3O7B A;  4YQK A;  5GMC A;  4MCD A;  4YQ0 A;  4X3L A;  4MCC A;  4KDZ A;  2QMM A;  1NS5 A;  2CX8 A;  1TRO A;  3KW2 A;  3N4J A;  2V3J A;  4L69 A;  3NK6 A;  1RCS A;  3BBE A;  4YQO A;  4JAL A;  5GMB A;  5FAI A;  4YQT A;  4YQ8 A;  4CNF A;  3IC6 A;  2OZ9 R;  4YQG A;  1MI7 R;  4YVI A;  4YQ1 A;  1VH0 A;  4YQ9 A;  1O6D A;  3N4K A;  4YQS A;  4YQQ A;  2O3A A;  4YQR A;  3BBH A;  4YPZ A;  3IEF A;  4CNE A;  4YPX A;  1X7P A;  2QWV A;  3SSX N;  3WRP A;  2YY8 A;  2EGV A;  1UAM A;  1MXI A;  3OII A; 
#chains in the Genus database with same CATH homology
 1UAJ A;  4YQ7 A;  4YQN A;  4YVJ A;  4H3Z A;  4CNG A;  4YPW A;  4YQ4 A;  1IPA A;  1X7O A;  4YQ6 A;  4YQ2 A;  1VHK A;  3NK7 A;  1Z85 A;  4FMW A;  4YVG A;  5D9F A;  1P9P A;  4JWF A;  4J3C A;  3OIJ A;  3QUV A;  4YQC A;  3AXZ A;  3DCM X;  1UAL A;  1V2X A;  4YQJ A;  3KNU A;  4YQP A;  2EGW A;  4JWJ A;  2I6D A;  5CO4 A;  1ZJR A;  3AIA A;  3AI9 X;  3ILK A;  1UAK A;  4IG6 A;  1K3R A;  3ONP A;  4MCB A;  4KGN A;  4H3Y A;  4JWG A;  4JAK A;  4YPY A;  1VHY A;  4YVH A;  4YQD A;  3L8U A;  4CND A;  4YQB A;  4YQ3 A;  4YQI A;  2HA8 A;  1GZ0 A;  3KY7 A;  4FAK A;  3GYQ A;  4YQA A;  4PZK A;  5GM8 A;  3E5Y A;  1OY5 A;  1TO0 A;  4RG1 A;  1J85 A;  1NXZ A;  4YVK A;  3KTY A;  4YQL A;  2Z0Y A;  1V6Z A;  4XBO A;  3BBD A;  3OIN A;  4E8B A;  4JWH A;  4X3M A;  2V3K A;  4YQ5 A;  3O7B A;  4YQK A;  5GMC A;  4MCD A;  4YQ0 A;  4X3L A;  4MCC A;  4KDZ A;  2QMM A;  1NS5 A;  2CX8 A;  3KW2 A;  3N4J A;  2V3J A;  4L69 A;  3NK6 A;  3BBE A;  4YQO A;  4JAL A;  5GMB A;  5FAI A;  4YQT A;  4YQ8 A;  4CNF A;  3IC6 A;  4YQG A;  4YVI A;  4YQ1 A;  1VH0 A;  4YQ9 A;  1O6D A;  3N4K A;  4YQS A;  4YQQ A;  2O3A A;  4YQR A;  3BBH A;  4YPZ A;  3IEF A;  4CNE A;  4YPX A;  1X7P A;  2QWV A;  2YY8 A;  2EGV A;  1UAM A;  1MXI A;  3OII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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