4YQ3A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
253
structure length
242
Chain Sequence
GLVPRGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 242
sequence length 253
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq3A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq3A01
4YVHA 2CX8A 3OIJA 4YQTA 1IPAA 4YQ6A 4X3MA 3N4JA 4J3CA 3AXZA 4YQGA 5CO4A 4H3ZA 4IG6A 3OIIA 3BBDA 4PZKA 3DCMX 3ILKA 3NK7A 4YPXA 1X7PA 2Z0YA 1OY5A 4YVGA 2I6DA 5GMCA 4CNDA 1V6ZA 1MXIA 3O7BA 3KW2A 4YQ3A 4YQAA 1K3RA 2YY8A 2EGWA 3BBHA 4RG1A 4YQ2A 3NK6A 2HA8A 4CNEA 1NS5A 3GYQA 1ZJRA 3KTYA 1VH0A 1VHKA 4MCDA 1Z85A 4YQSA 1TO0A 4YVJA 4FAKA 4YQBA 3AIAA 1UALA 4MCBA 4YQPA 4YQOA 3BBEA 4YQ4A 4YQ1A 4YQLA 2V3KA 4JAKA 2O3AA 4YQ0A 1X7OA 1O6DA 4YQ7A 3AI9X 1V2XA 2QWVA 4YQCA 5GM8A 4E8BA 4YQIA 3E5YA 4H3YA 5FAIA 3L8UA 4YQKA 4YVIA 1VHYA 1P9PA 4KGNA 1NXZA 4CNGA 1UAKA 2V3JA 3KY7A 1UAMA 1J85A 3ONPA 4YVKA 2EGVA 4CNFA 4YPWA 4YPZA 4L69A 4YQ5A 2QMMA 4KDZA 4YQQA 4JALA 3OINA 5GMBA 3IEFA 5D9FA 3KNUA 1GZ0A 4YQ9A 4YQRA 1UAJA 3IC6A 3N4KA 4X3LA 4YPYA 4MCCA 4YQDA 3QUVA 4YQ8A 4YQJA 4XBOA 4YQNA
chains in the Genus database with same CATH superfamily
4YVHA 2CX8A 3OIJA 4JWGA 4YQTA 1IPAA 4YQ6A 4X3MA 3N4JA 1CO0A 4J3CA 2OZ9R 3AXZA 4YQGA 5CO4A 1TRRA 4H3ZA 4IG6A 1WRSR 3OIIA 3BBDA 1RCSA 4PZKA 3DCMX 3ILKA 3NK7A 4YPXA 1X7PA 2Z0YA 1OY5A 4YVGA 4JWHA 1WRPR 2I6DA 5GMCA 4CNDA 1MXIA 3G1CA 1V6ZA 3O7BA 3FRWA 3KW2A 4YQ3A 4YQAA 1K3RA 2YY8A 2EGWA 3BBHA 4RG1A 4YQ2A 3NK6A 2HA8A 4CNEA 1NS5A 3GYQA 1ZJRA 3KTYA 1VH0A 1VHKA 4MCDA 1Z85A 4YQSA 1TO0A 4YVJA 4FAKA 4YQBA 3AIAA 1UALA 4MCBA 4YQPA 4YQOA 3BBEA 4YQ4A 4YQ1A 1MI7R 4YQLA 2V3KA 4JAKA 2O3AA 4YQ0A 1X7OA 1O6DA 4YQ7A 3AI9X 1V2XA 2QWVA 4YQCA 5GM8A 4E8BA 4YQIA 3E5YA 4JWFA 3KORA 1WRTR 4H3YA 5FAIA 3L8UA 3SSWN 4YQKA 4YVIA 1VHYA 1P9PA 4KGNA 1NXZA 4CNGA 1UAKA 2V3JA 3KY7A 1UAMA 3SSXN 1J85A 3ONPA 4YVKA 2EGVA 4CNFA 4YPWA 3WRPA 4YPZA 4L69A 2XDIA 4YQ5A 2QMMA 4KDZA 4YQQA 4JALA 3OINA 5GMBA 3IEFA 1ZT9A 5D9FA 3KNUA 1GZ0A 4YQ9A 4YQRA 4JWJA 1UAJA 3IC6A 3N4KA 4X3LA 4YPYA 1TROA 4MCCA 4YQDA 4FMWA 1JHGA 3QUVA 4YQ8A 4YQJA 4XBOA 4YQNA
chains in the Genus database with same CATH topology
4YVHA 2CX8A 3OIJA 4JWGA 4YQTA 1IPAA 4YQ6A 4X3MA 3N4JA 4J3CA 3AXZA 4YQGA 5CO4A 4H3ZA 4IG6A 3OIIA 3BBDA 4PZKA 3DCMX 3ILKA 3NK7A 4YPXA 1X7PA 2Z0YA 1OY5A 4YVGA 4JWHA 2I6DA 5GMCA 4CNDA 1V6ZA 1MXIA 3O7BA 3KW2A 4YQ3A 4YQAA 1K3RA 2YY8A 2EGWA 3BBHA 4RG1A 4YQ2A 3NK6A 2HA8A 4CNEA 1NS5A 3GYQA 1ZJRA 3KTYA 1VH0A 1VHKA 4MCDA 1Z85A 4YQSA 1TO0A 4YVJA 4FAKA 4YQBA 3AIAA 1UALA 4MCBA 4YQPA 4YQOA 3BBEA 4YQ4A 4YQ1A 4YQLA 2V3KA 4JAKA 2O3AA 4YQ0A 1X7OA 1O6DA 4YQ7A 3AI9X 1V2XA 2QWVA 4YQCA 5GM8A 4E8BA 4YQIA 3E5YA 4JWFA 4H3YA 5FAIA 3L8UA 4YQKA 4YVIA 1VHYA 1P9PA 4KGNA 1NXZA 4CNGA 1UAKA 2V3JA 3KY7A 1UAMA 1J85A 3ONPA 4YVKA 2EGVA 4CNFA 4YPWA 4YPZA 4L69A 4YQ5A 2QMMA 4KDZA 4YQQA 4JALA 3OINA 5GMBA 3IEFA 5D9FA 3KNUA 1GZ0A 4YQ9A 4YQRA 4JWJA 1UAJA 3IC6A 3N4KA 4X3LA 4YPYA 4MCCA 4YQDA 4FMWA 3QUVA 4YQ8A 4YQJA 4XBOA 4YQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVH A;  2CX8 A;  3OIJ A;  4YQT A;  1IPA A;  4YQ6 A;  4X3M A;  3N4J A;  4J3C A;  3AXZ A;  4YQG A;  5CO4 A;  4H3Z A;  4IG6 A;  3OII A;  3BBD A;  4PZK A;  3DCM X;  3ILK A;  3NK7 A;  4YPX A;  1X7P A;  2Z0Y A;  1OY5 A;  4YVG A;  2I6D A;  5GMC A;  4CND A;  1V6Z A;  1MXI A;  3O7B A;  3KW2 A;  4YQ3 A;  4YQA A;  1K3R A;  2YY8 A;  2EGW A;  3BBH A;  4RG1 A;  4YQ2 A;  3NK6 A;  2HA8 A;  4CNE A;  1NS5 A;  3GYQ A;  1ZJR A;  3KTY A;  1VH0 A;  1VHK A;  4MCD A;  1Z85 A;  4YQS A;  1TO0 A;  4YVJ A;  4FAK A;  4YQB A;  3AIA A;  1UAL A;  4MCB A;  4YQP A;  4YQO A;  3BBE A;  4YQ4 A;  4YQ1 A;  4YQL A;  2V3K A;  4JAK A;  2O3A A;  4YQ0 A;  1X7O A;  1O6D A;  4YQ7 A;  3AI9 X;  1V2X A;  2QWV A;  4YQC A;  5GM8 A;  4E8B A;  4YQI A;  3E5Y A;  4H3Y A;  5FAI A;  3L8U A;  4YQK A;  4YVI A;  1VHY A;  1P9P A;  4KGN A;  1NXZ A;  4CNG A;  1UAK A;  2V3J A;  3KY7 A;  1UAM A;  1J85 A;  3ONP A;  4YVK A;  2EGV A;  4CNF A;  4YPW A;  4YPZ A;  4L69 A;  4YQ5 A;  2QMM A;  4KDZ A;  4YQQ A;  4JAL A;  3OIN A;  5GMB A;  3IEF A;  5D9F A;  3KNU A;  1GZ0 A;  4YQ9 A;  4YQR A;  1UAJ A;  3IC6 A;  3N4K A;  4X3L A;  4YPY A;  4MCC A;  4YQD A;  3QUV A;  4YQ8 A;  4YQJ A;  4XBO A;  4YQN A; 
#chains in the Genus database with same CATH topology
 4YVH A;  2CX8 A;  3OIJ A;  4JWG A;  4YQT A;  1IPA A;  4YQ6 A;  4X3M A;  3N4J A;  1CO0 A;  4J3C A;  2OZ9 R;  3AXZ A;  4YQG A;  5CO4 A;  1TRR A;  4H3Z A;  4IG6 A;  1WRS R;  3OII A;  3BBD A;  1RCS A;  4PZK A;  3DCM X;  3ILK A;  3NK7 A;  4YPX A;  1X7P A;  2Z0Y A;  1OY5 A;  4YVG A;  4JWH A;  1WRP R;  2I6D A;  5GMC A;  4CND A;  1MXI A;  3G1C A;  1V6Z A;  3O7B A;  3FRW A;  3KW2 A;  4YQ3 A;  4YQA A;  1K3R A;  2YY8 A;  2EGW A;  3BBH A;  4RG1 A;  4YQ2 A;  3NK6 A;  2HA8 A;  4CNE A;  1NS5 A;  3GYQ A;  1ZJR A;  3KTY A;  1VH0 A;  1VHK A;  4MCD A;  1Z85 A;  4YQS A;  1TO0 A;  4YVJ A;  4FAK A;  4YQB A;  3AIA A;  1UAL A;  4MCB A;  4YQP A;  4YQO A;  3BBE A;  4YQ4 A;  4YQ1 A;  1MI7 R;  4YQL A;  2V3K A;  4JAK A;  2O3A A;  4YQ0 A;  1X7O A;  1O6D A;  4YQ7 A;  3AI9 X;  1V2X A;  2QWV A;  4YQC A;  5GM8 A;  4E8B A;  4YQI A;  3E5Y A;  4JWF A;  3KOR A;  1WRT R;  4H3Y A;  5FAI A;  3L8U A;  3SSW N;  4YQK A;  4YVI A;  1VHY A;  1P9P A;  4KGN A;  1NXZ A;  4CNG A;  1UAK A;  2V3J A;  3KY7 A;  1UAM A;  3SSX N;  1J85 A;  3ONP A;  4YVK A;  2EGV A;  4CNF A;  4YPW A;  3WRP A;  4YPZ A;  4L69 A;  2XDI A;  4YQ5 A;  2QMM A;  4KDZ A;  4YQQ A;  4JAL A;  3OIN A;  5GMB A;  3IEF A;  1ZT9 A;  5D9F A;  3KNU A;  1GZ0 A;  4YQ9 A;  4YQR A;  4JWJ A;  1UAJ A;  3IC6 A;  3N4K A;  4X3L A;  4YPY A;  1TRO A;  4MCC A;  4YQD A;  4FMW A;  1JHG A;  3QUV A;  4YQ8 A;  4YQJ A;  4XBO A;  4YQN A; 
#chains in the Genus database with same CATH homology
 4YVH A;  2CX8 A;  3OIJ A;  4JWG A;  4YQT A;  1IPA A;  4YQ6 A;  4X3M A;  3N4J A;  4J3C A;  3AXZ A;  4YQG A;  5CO4 A;  4H3Z A;  4IG6 A;  3OII A;  3BBD A;  4PZK A;  3DCM X;  3ILK A;  3NK7 A;  4YPX A;  1X7P A;  2Z0Y A;  1OY5 A;  4YVG A;  4JWH A;  2I6D A;  5GMC A;  4CND A;  1V6Z A;  1MXI A;  3O7B A;  3KW2 A;  4YQ3 A;  4YQA A;  1K3R A;  2YY8 A;  2EGW A;  3BBH A;  4RG1 A;  4YQ2 A;  3NK6 A;  2HA8 A;  4CNE A;  1NS5 A;  3GYQ A;  1ZJR A;  3KTY A;  1VH0 A;  1VHK A;  4MCD A;  1Z85 A;  4YQS A;  1TO0 A;  4YVJ A;  4FAK A;  4YQB A;  3AIA A;  1UAL A;  4MCB A;  4YQP A;  4YQO A;  3BBE A;  4YQ4 A;  4YQ1 A;  4YQL A;  2V3K A;  4JAK A;  2O3A A;  4YQ0 A;  1X7O A;  1O6D A;  4YQ7 A;  3AI9 X;  1V2X A;  2QWV A;  4YQC A;  5GM8 A;  4E8B A;  4YQI A;  3E5Y A;  4JWF A;  4H3Y A;  5FAI A;  3L8U A;  4YQK A;  4YVI A;  1VHY A;  1P9P A;  4KGN A;  1NXZ A;  4CNG A;  1UAK A;  2V3J A;  3KY7 A;  1UAM A;  1J85 A;  3ONP A;  4YVK A;  2EGV A;  4CNF A;  4YPW A;  4YPZ A;  4L69 A;  4YQ5 A;  2QMM A;  4KDZ A;  4YQQ A;  4JAL A;  3OIN A;  5GMB A;  3IEF A;  5D9F A;  3KNU A;  1GZ0 A;  4YQ9 A;  4YQR A;  4JWJ A;  1UAJ A;  3IC6 A;  3N4K A;  4X3L A;  4YPY A;  4MCC A;  4YQD A;  4FMW A;  3QUV A;  4YQ8 A;  4YQJ A;  4XBO A;  4YQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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