4YQ3A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
253
structure length
242
Chain Sequence
GLVPRGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 242
sequence length 253
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq3A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq3A01
4CNGA 4YQKA 4YQCA 4CNEA 3BBHA 3ILKA 1NS5A 1P9PA 4MCCA 2V3KA 4FAKA 1IPAA 3IEFA 4JALA 4YQAA 4JAKA 4YQ8A 5FAIA 1OY5A 4YVGA 2QMMA 2EGVA 4X3MA 3NK7A 4MCDA 1MXIA 1O6DA 3BBDA 4YQ4A 4YQ9A 3OIJA 3OIIA 4YQPA 4YPZA 1ZJRA 1UALA 1VHYA 4H3YA 4YQIA 2O3AA 3BBEA 2HA8A 4YQ7A 3KY7A 3E5YA 4YQ1A 1V2XA 1X7OA 4CNFA 3L8UA 3GYQA 4YQ3A 4YQ0A 4X3LA 5CO4A 1GZ0A 3QUVA 3IC6A 4CNDA 1UAMA 4YQBA 3ONPA 3N4KA 3N4JA 4YQQA 3OINA 3NK6A 4YPWA 4YQSA 3DCMX 4YQDA 4H3ZA 4YQTA 4YVJA 4YVKA 4YVHA 1Z85A 3O7BA 4YPXA 4E8BA 3AIAA 1VH0A 3KNUA 4RG1A 2Z0YA 1K3RA 1VHKA 1J85A 4PZKA 3AI9X 3KW2A 4KDZA 1X7PA 5GMBA 2YY8A 4YQGA 2I6DA 4YQJA 4L69A 4YQ6A 4J3CA 4YQLA 4MCBA 4XBOA 1V6ZA 4YQRA 1NXZA 2EGWA 5GMCA 4IG6A 5GM8A 4YQOA 1TO0A 5D9FA 4YPYA 2CX8A 1UAJA 2V3JA 4YQNA 4KGNA 3AXZA 4YVIA 4YQ2A 3KTYA 1UAKA 2QWVA 4YQ5A
chains in the Genus database with same CATH superfamily
3SSWN 1ZT9A 4CNGA 4YQKA 4YQCA 4CNEA 3BBHA 3ILKA 1NS5A 1WRPR 1P9PA 4MCCA 1WRSR 2V3KA 4FAKA 1IPAA 3IEFA 4JALA 4YQAA 4JAKA 4YQ8A 5FAIA 1OY5A 4JWGA 4YVGA 2QMMA 2EGVA 4X3MA 3NK7A 4JWJA 4MCDA 1TRRA 1MXIA 1O6DA 3BBDA 3WRPA 4YQ4A 4YQ9A 3OIJA 3OIIA 4YQPA 1WRTR 4YPZA 1ZJRA 1UALA 1VHYA 4H3YA 4YQIA 2O3AA 3BBEA 2HA8A 4YQ7A 3KY7A 3E5YA 4YQ1A 1V2XA 1X7OA 4CNFA 3L8UA 3GYQA 4YQ3A 4YQ0A 4X3LA 5CO4A 1GZ0A 3QUVA 3IC6A 4CNDA 3KORA 1UAMA 4YQBA 3ONPA 3N4KA 3N4JA 4YQQA 3OINA 3NK6A 4YPWA 4YQSA 3DCMX 4YQDA 4H3ZA 1TROA 4YQTA 4YVJA 4YVKA 4YVHA 1Z85A 3O7BA 4YPXA 4E8BA 3AIAA 1VH0A 3SSXN 3KNUA 4RG1A 2Z0YA 1K3RA 1VHKA 1J85A 2XDIA 1CO0A 3AI9X 3KW2A 4KDZA 1X7PA 4PZKA 2YY8A 5GMBA 4YQGA 2I6DA 4YQJA 4L69A 4YQ6A 4J3CA 4YQLA 4MCBA 4XBOA 1V6ZA 3FRWA 4YQRA 1MI7R 1RCSA 1NXZA 2EGWA 5GMCA 4IG6A 4JWHA 2OZ9R 5GM8A 4YQOA 4FMWA 1TO0A 3G1CA 4JWFA 5D9FA 4YPYA 2CX8A 1UAJA 2V3JA 4YQNA 1JHGA 4KGNA 3AXZA 4YVIA 4YQ2A 3KTYA 1UAKA 2QWVA 4YQ5A
chains in the Genus database with same CATH topology
4CNGA 4YQKA 4YQCA 4CNEA 3BBHA 3ILKA 1NS5A 1P9PA 4MCCA 2V3KA 4FAKA 1IPAA 3IEFA 4JALA 4YQAA 4JAKA 4YQ8A 5FAIA 1OY5A 4JWGA 4YVGA 2QMMA 2EGVA 4X3MA 3NK7A 4JWJA 4MCDA 1MXIA 1O6DA 3BBDA 4YQ4A 4YQ9A 3OIJA 3OIIA 4YQPA 4YPZA 1ZJRA 1UALA 1VHYA 4H3YA 4YQIA 2O3AA 3BBEA 2HA8A 4YQ7A 3KY7A 3E5YA 4YQ1A 1V2XA 1X7OA 4CNFA 3L8UA 3GYQA 4YQ3A 4YQ0A 4X3LA 5CO4A 1GZ0A 3QUVA 3IC6A 4CNDA 1UAMA 4YQBA 3ONPA 3N4KA 3N4JA 4YQQA 3OINA 3NK6A 4YPWA 4YQSA 3DCMX 4YQDA 4H3ZA 4YQTA 4YVJA 4YVKA 4YVHA 1Z85A 3O7BA 4YPXA 4E8BA 3AIAA 1VH0A 3KNUA 4RG1A 2Z0YA 1K3RA 1VHKA 1J85A 4PZKA 3AI9X 3KW2A 4KDZA 1X7PA 5GMBA 2YY8A 4YQGA 2I6DA 4YQJA 4L69A 4YQ6A 4J3CA 4YQLA 4MCBA 4XBOA 1V6ZA 4YQRA 1NXZA 2EGWA 5GMCA 4IG6A 4JWHA 5GM8A 4YQOA 4FMWA 1TO0A 4JWFA 5D9FA 4YPYA 2CX8A 1UAJA 2V3JA 4YQNA 4KGNA 3AXZA 4YVIA 4YQ2A 3KTYA 1UAKA 2QWVA 4YQ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CNG A;  4YQK A;  4YQC A;  4CNE A;  3BBH A;  3ILK A;  1NS5 A;  1P9P A;  4MCC A;  2V3K A;  4FAK A;  1IPA A;  3IEF A;  4JAL A;  4YQA A;  4JAK A;  4YQ8 A;  5FAI A;  1OY5 A;  4YVG A;  2QMM A;  2EGV A;  4X3M A;  3NK7 A;  4MCD A;  1MXI A;  1O6D A;  3BBD A;  4YQ4 A;  4YQ9 A;  3OIJ A;  3OII A;  4YQP A;  4YPZ A;  1ZJR A;  1UAL A;  1VHY A;  4H3Y A;  4YQI A;  2O3A A;  3BBE A;  2HA8 A;  4YQ7 A;  3KY7 A;  3E5Y A;  4YQ1 A;  1V2X A;  1X7O A;  4CNF A;  3L8U A;  3GYQ A;  4YQ3 A;  4YQ0 A;  4X3L A;  5CO4 A;  1GZ0 A;  3QUV A;  3IC6 A;  4CND A;  1UAM A;  4YQB A;  3ONP A;  3N4K A;  3N4J A;  4YQQ A;  3OIN A;  3NK6 A;  4YPW A;  4YQS A;  3DCM X;  4YQD A;  4H3Z A;  4YQT A;  4YVJ A;  4YVK A;  4YVH A;  1Z85 A;  3O7B A;  4YPX A;  4E8B A;  3AIA A;  1VH0 A;  3KNU A;  4RG1 A;  2Z0Y A;  1K3R A;  1VHK A;  1J85 A;  4PZK A;  3AI9 X;  3KW2 A;  4KDZ A;  1X7P A;  5GMB A;  2YY8 A;  4YQG A;  2I6D A;  4YQJ A;  4L69 A;  4YQ6 A;  4J3C A;  4YQL A;  4MCB A;  4XBO A;  1V6Z A;  4YQR A;  1NXZ A;  2EGW A;  5GMC A;  4IG6 A;  5GM8 A;  4YQO A;  1TO0 A;  5D9F A;  4YPY A;  2CX8 A;  1UAJ A;  2V3J A;  4YQN A;  4KGN A;  3AXZ A;  4YVI A;  4YQ2 A;  3KTY A;  1UAK A;  2QWV A;  4YQ5 A; 
#chains in the Genus database with same CATH topology
 3SSW N;  1ZT9 A;  4CNG A;  4YQK A;  4YQC A;  4CNE A;  3BBH A;  3ILK A;  1NS5 A;  1WRP R;  1P9P A;  4MCC A;  1WRS R;  2V3K A;  4FAK A;  1IPA A;  3IEF A;  4JAL A;  4YQA A;  4JAK A;  4YQ8 A;  5FAI A;  1OY5 A;  4JWG A;  4YVG A;  2QMM A;  2EGV A;  4X3M A;  3NK7 A;  4JWJ A;  4MCD A;  1TRR A;  1MXI A;  1O6D A;  3BBD A;  3WRP A;  4YQ4 A;  4YQ9 A;  3OIJ A;  3OII A;  4YQP A;  1WRT R;  4YPZ A;  1ZJR A;  1UAL A;  1VHY A;  4H3Y A;  4YQI A;  2O3A A;  3BBE A;  2HA8 A;  4YQ7 A;  3KY7 A;  3E5Y A;  4YQ1 A;  1V2X A;  1X7O A;  4CNF A;  3L8U A;  3GYQ A;  4YQ3 A;  4YQ0 A;  4X3L A;  5CO4 A;  1GZ0 A;  3QUV A;  3IC6 A;  4CND A;  3KOR A;  1UAM A;  4YQB A;  3ONP A;  3N4K A;  3N4J A;  4YQQ A;  3OIN A;  3NK6 A;  4YPW A;  4YQS A;  3DCM X;  4YQD A;  4H3Z A;  1TRO A;  4YQT A;  4YVJ A;  4YVK A;  4YVH A;  1Z85 A;  3O7B A;  4YPX A;  4E8B A;  3AIA A;  1VH0 A;  3SSX N;  3KNU A;  4RG1 A;  2Z0Y A;  1K3R A;  1VHK A;  1J85 A;  2XDI A;  1CO0 A;  3AI9 X;  3KW2 A;  4KDZ A;  1X7P A;  4PZK A;  2YY8 A;  5GMB A;  4YQG A;  2I6D A;  4YQJ A;  4L69 A;  4YQ6 A;  4J3C A;  4YQL A;  4MCB A;  4XBO A;  1V6Z A;  3FRW A;  4YQR A;  1MI7 R;  1RCS A;  1NXZ A;  2EGW A;  5GMC A;  4IG6 A;  4JWH A;  2OZ9 R;  5GM8 A;  4YQO A;  4FMW A;  1TO0 A;  3G1C A;  4JWF A;  5D9F A;  4YPY A;  2CX8 A;  1UAJ A;  2V3J A;  4YQN A;  1JHG A;  4KGN A;  3AXZ A;  4YVI A;  4YQ2 A;  3KTY A;  1UAK A;  2QWV A;  4YQ5 A; 
#chains in the Genus database with same CATH homology
 4CNG A;  4YQK A;  4YQC A;  4CNE A;  3BBH A;  3ILK A;  1NS5 A;  1P9P A;  4MCC A;  2V3K A;  4FAK A;  1IPA A;  3IEF A;  4JAL A;  4YQA A;  4JAK A;  4YQ8 A;  5FAI A;  1OY5 A;  4JWG A;  4YVG A;  2QMM A;  2EGV A;  4X3M A;  3NK7 A;  4JWJ A;  4MCD A;  1MXI A;  1O6D A;  3BBD A;  4YQ4 A;  4YQ9 A;  3OIJ A;  3OII A;  4YQP A;  4YPZ A;  1ZJR A;  1UAL A;  1VHY A;  4H3Y A;  4YQI A;  2O3A A;  3BBE A;  2HA8 A;  4YQ7 A;  3KY7 A;  3E5Y A;  4YQ1 A;  1V2X A;  1X7O A;  4CNF A;  3L8U A;  3GYQ A;  4YQ3 A;  4YQ0 A;  4X3L A;  5CO4 A;  1GZ0 A;  3QUV A;  3IC6 A;  4CND A;  1UAM A;  4YQB A;  3ONP A;  3N4K A;  3N4J A;  4YQQ A;  3OIN A;  3NK6 A;  4YPW A;  4YQS A;  3DCM X;  4YQD A;  4H3Z A;  4YQT A;  4YVJ A;  4YVK A;  4YVH A;  1Z85 A;  3O7B A;  4YPX A;  4E8B A;  3AIA A;  1VH0 A;  3KNU A;  4RG1 A;  2Z0Y A;  1K3R A;  1VHK A;  1J85 A;  4PZK A;  3AI9 X;  3KW2 A;  4KDZ A;  1X7P A;  5GMB A;  2YY8 A;  4YQG A;  2I6D A;  4YQJ A;  4L69 A;  4YQ6 A;  4J3C A;  4YQL A;  4MCB A;  4XBO A;  1V6Z A;  4YQR A;  1NXZ A;  2EGW A;  5GMC A;  4IG6 A;  4JWH A;  5GM8 A;  4YQO A;  4FMW A;  1TO0 A;  4JWF A;  5D9F A;  4YPY A;  2CX8 A;  1UAJ A;  2V3J A;  4YQN A;  4KGN A;  3AXZ A;  4YVI A;  4YQ2 A;  3KTY A;  1UAK A;  2QWV A;  4YQ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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