4YQ4A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
249
structure length
242
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 74
structure length 242
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq4A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq4A01
2V3KA 4YVIA 4H3ZA 3N4JA 2V3JA 5D9FA 3OINA 2CX8A 4YQJA 4YPXA 4YQAA 1K3RA 4J3CA 1OY5A 4YQ9A 3IEFA 4YPZA 4CNFA 2I6DA 4YQBA 3KY7A 4YQ5A 5CO4A 1IPAA 3N4KA 4IG6A 3O7BA 1NS5A 2QWVA 3L8UA 1UALA 4YQIA 4YQGA 4YQQA 3ILKA 2O3AA 3E5YA 4YQ2A 1J85A 5GMBA 1UAJA 4XBOA 1ZJRA 5FAIA 4YPYA 1UAMA 1GZ0A 3BBEA 4PZKA 4YQDA 2Z0YA 3AXZA 3IC6A 4X3MA 1VH0A 4YQRA 3NK7A 3ONPA 4YQNA 5GMCA 4YPWA 4YQCA 1TO0A 3BBDA 3QUVA 4YQ0A 1O6DA 4JALA 2YY8A 4KGNA 4JAKA 4CNEA 3BBHA 3AI9X 4YQOA 4E8BA 4YQKA 4YQ3A 1X7OA 4MCCA 1MXIA 2QMMA 2HA8A 1Z85A 3OIIA 4CNDA 4YVGA 4YVHA 4YQTA 4CNGA 3KW2A 3DCMX 4YQSA 5GM8A 3AIAA 4H3YA 3OIJA 4YQ7A 4YQLA 4YQ4A 3KTYA 3NK6A 4YQ6A 1VHYA 4MCBA 1X7PA 1NXZA 4YQPA 2EGVA 3KNUA 3GYQA 1VHKA 4FAKA 4KDZA 1UAKA 4YQ8A 4MCDA 1P9PA 4YVKA 1V6ZA 4L69A 4YVJA 4RG1A 2EGWA 1V2XA 4YQ1A 4X3LA
chains in the Genus database with same CATH superfamily
4JWGA 2V3KA 4YVIA 4H3ZA 1WRPR 3N4JA 2V3JA 5D9FA 3OINA 2CX8A 4YQJA 4YPXA 4YQAA 1WRTR 1K3RA 4J3CA 1OY5A 3WRPA 3IEFA 4YQ9A 4YPZA 4CNFA 2I6DA 1JHGA 3KY7A 4YQBA 4YQ5A 5CO4A 1IPAA 3N4KA 1WRSR 4IG6A 3O7BA 1NS5A 2QWVA 3L8UA 1UALA 4YQIA 4YQGA 4YQQA 3ILKA 2O3AA 3E5YA 4YQ2A 1J85A 5GMBA 1UAJA 4XBOA 1ZJRA 2XDIA 5FAIA 4YPYA 4FMWA 4JWFA 1UAMA 1GZ0A 3BBEA 3FRWA 4PZKA 4YQDA 2Z0YA 3AXZA 3IC6A 4X3MA 1CO0A 1VH0A 4YQRA 3NK7A 3ONPA 4YQNA 4JWHA 5GMCA 4YPWA 4YQCA 1TO0A 1MI7R 3BBDA 3QUVA 4YQ0A 1O6DA 4JALA 2YY8A 3SSWN 4KGNA 4JAKA 4CNEA 2OZ9R 3BBHA 3AI9X 4YQOA 4E8BA 4YQKA 4YQ3A 1X7OA 4MCCA 1MXIA 2QMMA 2HA8A 1Z85A 3G1CA 3OIIA 4CNDA 1RCSA 4YVGA 4YVHA 4YQTA 4CNGA 3KW2A 3DCMX 3SSXN 4JWJA 4YQSA 5GM8A 3AIAA 4H3YA 3OIJA 4YQ7A 4YQLA 4YQ4A 3KTYA 3NK6A 4YQ6A 1VHYA 4MCBA 1X7PA 1NXZA 1TROA 4YQPA 2EGVA 3KNUA 3GYQA 1VHKA 3KORA 4FAKA 4KDZA 1UAKA 4YQ8A 4MCDA 1P9PA 4YVKA 1V6ZA 4L69A 4YVJA 1TRRA 4RG1A 2EGWA 1ZT9A 1V2XA 4YQ1A 4X3LA
chains in the Genus database with same CATH topology
4JWGA 2V3KA 4YVIA 4H3ZA 3N4JA 2V3JA 5D9FA 3OINA 2CX8A 4YQJA 4YPXA 4YQAA 1K3RA 4J3CA 1OY5A 4YQ9A 3IEFA 4YPZA 4CNFA 2I6DA 4YQBA 3KY7A 4YQ5A 5CO4A 1IPAA 3N4KA 4IG6A 3O7BA 1NS5A 2QWVA 3L8UA 1UALA 4YQIA 4YQGA 4YQQA 3ILKA 2O3AA 3E5YA 4YQ2A 1J85A 5GMBA 1UAJA 4XBOA 1ZJRA 5FAIA 4YPYA 4FMWA 4JWFA 1UAMA 1GZ0A 3BBEA 4PZKA 4YQDA 2Z0YA 3AXZA 3IC6A 4X3MA 1VH0A 4YQRA 3NK7A 3ONPA 4YQNA 4JWHA 5GMCA 4YPWA 4YQCA 1TO0A 3BBDA 3QUVA 4YQ0A 1O6DA 4JALA 2YY8A 4KGNA 4JAKA 4CNEA 3BBHA 3AI9X 4YQOA 4E8BA 4YQKA 4YQ3A 1X7OA 4MCCA 1MXIA 2QMMA 2HA8A 1Z85A 3OIIA 4CNDA 4YVGA 4YVHA 4YQTA 4CNGA 3KW2A 3DCMX 4JWJA 4YQSA 5GM8A 3AIAA 4H3YA 3OIJA 4YQ7A 4YQLA 4YQ4A 3KTYA 3NK6A 4YQ6A 1VHYA 4MCBA 1X7PA 1NXZA 4YQPA 2EGVA 3KNUA 3GYQA 1VHKA 4FAKA 4KDZA 1UAKA 4YQ8A 4MCDA 1P9PA 4YVKA 1V6ZA 4L69A 4YVJA 4RG1A 2EGWA 1V2XA 4YQ1A 4X3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V3K A;  4YVI A;  4H3Z A;  3N4J A;  2V3J A;  5D9F A;  3OIN A;  2CX8 A;  4YQJ A;  4YPX A;  4YQA A;  1K3R A;  4J3C A;  1OY5 A;  4YQ9 A;  3IEF A;  4YPZ A;  4CNF A;  2I6D A;  4YQB A;  3KY7 A;  4YQ5 A;  5CO4 A;  1IPA A;  3N4K A;  4IG6 A;  3O7B A;  1NS5 A;  2QWV A;  3L8U A;  1UAL A;  4YQI A;  4YQG A;  4YQQ A;  3ILK A;  2O3A A;  3E5Y A;  4YQ2 A;  1J85 A;  5GMB A;  1UAJ A;  4XBO A;  1ZJR A;  5FAI A;  4YPY A;  1UAM A;  1GZ0 A;  3BBE A;  4PZK A;  4YQD A;  2Z0Y A;  3AXZ A;  3IC6 A;  4X3M A;  1VH0 A;  4YQR A;  3NK7 A;  3ONP A;  4YQN A;  5GMC A;  4YPW A;  4YQC A;  1TO0 A;  3BBD A;  3QUV A;  4YQ0 A;  1O6D A;  4JAL A;  2YY8 A;  4KGN A;  4JAK A;  4CNE A;  3BBH A;  3AI9 X;  4YQO A;  4E8B A;  4YQK A;  4YQ3 A;  1X7O A;  4MCC A;  1MXI A;  2QMM A;  2HA8 A;  1Z85 A;  3OII A;  4CND A;  4YVG A;  4YVH A;  4YQT A;  4CNG A;  3KW2 A;  3DCM X;  4YQS A;  5GM8 A;  3AIA A;  4H3Y A;  3OIJ A;  4YQ7 A;  4YQL A;  4YQ4 A;  3KTY A;  3NK6 A;  4YQ6 A;  1VHY A;  4MCB A;  1X7P A;  1NXZ A;  4YQP A;  2EGV A;  3KNU A;  3GYQ A;  1VHK A;  4FAK A;  4KDZ A;  1UAK A;  4YQ8 A;  4MCD A;  1P9P A;  4YVK A;  1V6Z A;  4L69 A;  4YVJ A;  4RG1 A;  2EGW A;  1V2X A;  4YQ1 A;  4X3L A; 
#chains in the Genus database with same CATH topology
 4JWG A;  2V3K A;  4YVI A;  4H3Z A;  1WRP R;  3N4J A;  2V3J A;  5D9F A;  3OIN A;  2CX8 A;  4YQJ A;  4YPX A;  4YQA A;  1WRT R;  1K3R A;  4J3C A;  1OY5 A;  3WRP A;  3IEF A;  4YQ9 A;  4YPZ A;  4CNF A;  2I6D A;  1JHG A;  3KY7 A;  4YQB A;  4YQ5 A;  5CO4 A;  1IPA A;  3N4K A;  1WRS R;  4IG6 A;  3O7B A;  1NS5 A;  2QWV A;  3L8U A;  1UAL A;  4YQI A;  4YQG A;  4YQQ A;  3ILK A;  2O3A A;  3E5Y A;  4YQ2 A;  1J85 A;  5GMB A;  1UAJ A;  4XBO A;  1ZJR A;  2XDI A;  5FAI A;  4YPY A;  4FMW A;  4JWF A;  1UAM A;  1GZ0 A;  3BBE A;  3FRW A;  4PZK A;  4YQD A;  2Z0Y A;  3AXZ A;  3IC6 A;  4X3M A;  1CO0 A;  1VH0 A;  4YQR A;  3NK7 A;  3ONP A;  4YQN A;  4JWH A;  5GMC A;  4YPW A;  4YQC A;  1TO0 A;  1MI7 R;  3BBD A;  3QUV A;  4YQ0 A;  1O6D A;  4JAL A;  2YY8 A;  3SSW N;  4KGN A;  4JAK A;  4CNE A;  2OZ9 R;  3BBH A;  3AI9 X;  4YQO A;  4E8B A;  4YQK A;  4YQ3 A;  1X7O A;  4MCC A;  1MXI A;  2QMM A;  2HA8 A;  1Z85 A;  3G1C A;  3OII A;  4CND A;  1RCS A;  4YVG A;  4YVH A;  4YQT A;  4CNG A;  3KW2 A;  3DCM X;  3SSX N;  4JWJ A;  4YQS A;  5GM8 A;  3AIA A;  4H3Y A;  3OIJ A;  4YQ7 A;  4YQL A;  4YQ4 A;  3KTY A;  3NK6 A;  4YQ6 A;  1VHY A;  4MCB A;  1X7P A;  1NXZ A;  1TRO A;  4YQP A;  2EGV A;  3KNU A;  3GYQ A;  1VHK A;  3KOR A;  4FAK A;  4KDZ A;  1UAK A;  4YQ8 A;  4MCD A;  1P9P A;  4YVK A;  1V6Z A;  4L69 A;  4YVJ A;  1TRR A;  4RG1 A;  2EGW A;  1ZT9 A;  1V2X A;  4YQ1 A;  4X3L A; 
#chains in the Genus database with same CATH homology
 4JWG A;  2V3K A;  4YVI A;  4H3Z A;  3N4J A;  2V3J A;  5D9F A;  3OIN A;  2CX8 A;  4YQJ A;  4YPX A;  4YQA A;  1K3R A;  4J3C A;  1OY5 A;  4YQ9 A;  3IEF A;  4YPZ A;  4CNF A;  2I6D A;  4YQB A;  3KY7 A;  4YQ5 A;  5CO4 A;  1IPA A;  3N4K A;  4IG6 A;  3O7B A;  1NS5 A;  2QWV A;  3L8U A;  1UAL A;  4YQI A;  4YQG A;  4YQQ A;  3ILK A;  2O3A A;  3E5Y A;  4YQ2 A;  1J85 A;  5GMB A;  1UAJ A;  4XBO A;  1ZJR A;  5FAI A;  4YPY A;  4FMW A;  4JWF A;  1UAM A;  1GZ0 A;  3BBE A;  4PZK A;  4YQD A;  2Z0Y A;  3AXZ A;  3IC6 A;  4X3M A;  1VH0 A;  4YQR A;  3NK7 A;  3ONP A;  4YQN A;  4JWH A;  5GMC A;  4YPW A;  4YQC A;  1TO0 A;  3BBD A;  3QUV A;  4YQ0 A;  1O6D A;  4JAL A;  2YY8 A;  4KGN A;  4JAK A;  4CNE A;  3BBH A;  3AI9 X;  4YQO A;  4E8B A;  4YQK A;  4YQ3 A;  1X7O A;  4MCC A;  1MXI A;  2QMM A;  2HA8 A;  1Z85 A;  3OII A;  4CND A;  4YVG A;  4YVH A;  4YQT A;  4CNG A;  3KW2 A;  3DCM X;  4JWJ A;  4YQS A;  5GM8 A;  3AIA A;  4H3Y A;  3OIJ A;  4YQ7 A;  4YQL A;  4YQ4 A;  3KTY A;  3NK6 A;  4YQ6 A;  1VHY A;  4MCB A;  1X7P A;  1NXZ A;  4YQP A;  2EGV A;  3KNU A;  3GYQ A;  1VHK A;  4FAK A;  4KDZ A;  1UAK A;  4YQ8 A;  4MCD A;  1P9P A;  4YVK A;  1V6Z A;  4L69 A;  4YVJ A;  4RG1 A;  2EGW A;  1V2X A;  4YQ1 A;  4X3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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