4YQ7A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 73
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq7A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq7A01
2QMMA 3BBEA 2QWVA 4YPZA 1IPAA 4FAKA 3ONPA 3N4JA 4H3ZA 4YPXA 3QUVA 2CX8A 3NK6A 4YQRA 3OIIA 4YQ0A 3OINA 4YQTA 4YPWA 5GMCA 4CNFA 1MXIA 4X3LA 4KDZA 4CNDA 1UAJA 3KTYA 5GM8A 3O7BA 1UAMA 4X3MA 4YVKA 3NK7A 4YPYA 4YQ9A 2V3JA 4H3YA 2EGVA 3OIJA 4L69A 3N4KA 4XBOA 4JAKA 1X7OA 4IG6A 4YQOA 4YVJA 4MCBA 3AIAA 3KY7A 4MCCA 1X7PA 3AI9X 1ZJRA 5CO4A 4YQ4A 4YVIA 4YQ2A 3BBDA 2Z0YA 4E8BA 5D9FA 2O3AA 1VHKA 4YQKA 5FAIA 1NXZA 2V3KA 4YQLA 4YQ5A 1TO0A 4YQQA 4JALA 4YQJA 3IEFA 4YQ8A 1J85A 4YQBA 4YQPA 1Z85A 4MCDA 1GZ0A 4YVHA 4RG1A 2HA8A 4J3CA 1V2XA 3BBHA 4YQ7A 3DCMX 1VHYA 4YQGA 1P9PA 4YQIA 4YQ1A 4YQDA 4CNEA 1UAKA 4YVGA 1K3RA 4YQNA 3E5YA 3KW2A 4YQAA 4YQ6A 1NS5A 3ILKA 5GMBA 4CNGA 3L8UA 1O6DA 1OY5A 4KGNA 2EGWA 2I6DA 4PZKA 3KNUA 3AXZA 1VH0A 1V6ZA 4YQCA 4YQSA 4YQ3A 3IC6A 3GYQA 2YY8A 1UALA
chains in the Genus database with same CATH superfamily
2OZ9R 2QMMA 1WRPR 3BBEA 2QWVA 4YPZA 1TROA 1UALA 2XDIA 1ZT9A 1IPAA 4FAKA 3ONPA 3N4JA 4H3ZA 4YPXA 4JWGA 3QUVA 2CX8A 3NK6A 4YQRA 3SSXN 3OIIA 4YQ0A 3OINA 1MI7R 4YQTA 4YPWA 5GMCA 4CNFA 1RCSA 1MXIA 3KORA 4X3LA 4KDZA 1CO0A 4CNDA 1UAJA 3KTYA 5GM8A 3O7BA 1UAMA 4X3MA 4YVKA 3NK7A 4YPYA 4YQ9A 2V3JA 4H3YA 2EGVA 3OIJA 1JHGA 4L69A 3N4KA 4XBOA 3WRPA 4JAKA 1X7OA 4IG6A 4YQOA 4YVJA 4MCBA 3AIAA 3KY7A 4MCCA 1X7PA 1TRRA 3AI9X 1ZJRA 5CO4A 4YQ4A 4YVIA 4YQ2A 1WRTR 3BBDA 2Z0YA 4E8BA 5D9FA 2O3AA 1VHKA 4JWHA 4YQKA 5FAIA 1NXZA 2V3KA 4YQLA 4YQ5A 1TO0A 4YQQA 4JALA 4YQJA 3IEFA 4YQ8A 1J85A 4YQBA 4YQPA 1Z85A 4MCDA 1GZ0A 4YVHA 4RG1A 2HA8A 4J3CA 1V2XA 3BBHA 4YQ7A 3DCMX 1VHYA 4YQGA 1P9PA 4YQIA 4YQ1A 3G1CA 4YQDA 4CNEA 1UAKA 1K3RA 4YQNA 3SSWN 3E5YA 4JWJA 3KW2A 4YQAA 4YQ6A 1NS5A 3ILKA 5GMBA 4CNGA 3L8UA 3FRWA 1O6DA 1WRSR 1OY5A 4KGNA 2EGWA 2I6DA 4PZKA 3KNUA 3AXZA 1VH0A 1V6ZA 4YQCA 4JWFA 4YQSA 4FMWA 4YQ3A 3IC6A 3GYQA 2YY8A 4YVGA
chains in the Genus database with same CATH topology
2QMMA 3BBEA 2QWVA 4YPZA 1IPAA 4FAKA 3ONPA 3N4JA 4H3ZA 4YPXA 4JWGA 3QUVA 2CX8A 3NK6A 4YQRA 3OIIA 4YQ0A 3OINA 4YQTA 4YPWA 5GMCA 4CNFA 1MXIA 4X3LA 4KDZA 4CNDA 1UAJA 3KTYA 5GM8A 3O7BA 1UAMA 4X3MA 4YVKA 3NK7A 4YPYA 4YQ9A 2V3JA 4H3YA 2EGVA 3OIJA 4L69A 3N4KA 4XBOA 4JAKA 1X7OA 4IG6A 4YQOA 4YVJA 4MCBA 3AIAA 3KY7A 4MCCA 1X7PA 3AI9X 1ZJRA 5CO4A 4YQ4A 4YVIA 4YQ2A 3BBDA 2Z0YA 4E8BA 5D9FA 2O3AA 1VHKA 4JWHA 4YQKA 5FAIA 1NXZA 2V3KA 4YQLA 4YQ5A 1TO0A 4YQQA 4JALA 4YQJA 3IEFA 4YQ8A 1J85A 4YQBA 4YQPA 1Z85A 4MCDA 1GZ0A 4YVHA 4RG1A 2HA8A 4J3CA 1V2XA 3BBHA 4YQ7A 3DCMX 1VHYA 4YQGA 1P9PA 4YQIA 4YQ1A 4YQDA 4CNEA 1UAKA 4YVGA 1K3RA 4YQNA 3E5YA 4JWJA 3KW2A 4YQAA 4YQ6A 1NS5A 3ILKA 5GMBA 4CNGA 3L8UA 1O6DA 1OY5A 4KGNA 2EGWA 2I6DA 4PZKA 3KNUA 3AXZA 1VH0A 1V6ZA 4YQCA 4JWFA 4YQSA 4FMWA 4YQ3A 3IC6A 3GYQA 2YY8A 1UALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QMM A;  3BBE A;  2QWV A;  4YPZ A;  1IPA A;  4FAK A;  3ONP A;  3N4J A;  4H3Z A;  4YPX A;  3QUV A;  2CX8 A;  3NK6 A;  4YQR A;  3OII A;  4YQ0 A;  3OIN A;  4YQT A;  4YPW A;  5GMC A;  4CNF A;  1MXI A;  4X3L A;  4KDZ A;  4CND A;  1UAJ A;  3KTY A;  5GM8 A;  3O7B A;  1UAM A;  4X3M A;  4YVK A;  3NK7 A;  4YPY A;  4YQ9 A;  2V3J A;  4H3Y A;  2EGV A;  3OIJ A;  4L69 A;  3N4K A;  4XBO A;  4JAK A;  1X7O A;  4IG6 A;  4YQO A;  4YVJ A;  4MCB A;  3AIA A;  3KY7 A;  4MCC A;  1X7P A;  3AI9 X;  1ZJR A;  5CO4 A;  4YQ4 A;  4YVI A;  4YQ2 A;  3BBD A;  2Z0Y A;  4E8B A;  5D9F A;  2O3A A;  1VHK A;  4YQK A;  5FAI A;  1NXZ A;  2V3K A;  4YQL A;  4YQ5 A;  1TO0 A;  4YQQ A;  4JAL A;  4YQJ A;  3IEF A;  4YQ8 A;  1J85 A;  4YQB A;  4YQP A;  1Z85 A;  4MCD A;  1GZ0 A;  4YVH A;  4RG1 A;  2HA8 A;  4J3C A;  1V2X A;  3BBH A;  4YQ7 A;  3DCM X;  1VHY A;  4YQG A;  1P9P A;  4YQI A;  4YQ1 A;  4YQD A;  4CNE A;  1UAK A;  4YVG A;  1K3R A;  4YQN A;  3E5Y A;  3KW2 A;  4YQA A;  4YQ6 A;  1NS5 A;  3ILK A;  5GMB A;  4CNG A;  3L8U A;  1O6D A;  1OY5 A;  4KGN A;  2EGW A;  2I6D A;  4PZK A;  3KNU A;  3AXZ A;  1VH0 A;  1V6Z A;  4YQC A;  4YQS A;  4YQ3 A;  3IC6 A;  3GYQ A;  2YY8 A;  1UAL A; 
#chains in the Genus database with same CATH topology
 2OZ9 R;  2QMM A;  1WRP R;  3BBE A;  2QWV A;  4YPZ A;  1TRO A;  1UAL A;  2XDI A;  1ZT9 A;  1IPA A;  4FAK A;  3ONP A;  3N4J A;  4H3Z A;  4YPX A;  4JWG A;  3QUV A;  2CX8 A;  3NK6 A;  4YQR A;  3SSX N;  3OII A;  4YQ0 A;  3OIN A;  1MI7 R;  4YQT A;  4YPW A;  5GMC A;  4CNF A;  1RCS A;  1MXI A;  3KOR A;  4X3L A;  4KDZ A;  1CO0 A;  4CND A;  1UAJ A;  3KTY A;  5GM8 A;  3O7B A;  1UAM A;  4X3M A;  4YVK A;  3NK7 A;  4YPY A;  4YQ9 A;  2V3J A;  4H3Y A;  2EGV A;  3OIJ A;  1JHG A;  4L69 A;  3N4K A;  4XBO A;  3WRP A;  4JAK A;  1X7O A;  4IG6 A;  4YQO A;  4YVJ A;  4MCB A;  3AIA A;  3KY7 A;  4MCC A;  1X7P A;  1TRR A;  3AI9 X;  1ZJR A;  5CO4 A;  4YQ4 A;  4YVI A;  4YQ2 A;  1WRT R;  3BBD A;  2Z0Y A;  4E8B A;  5D9F A;  2O3A A;  1VHK A;  4JWH A;  4YQK A;  5FAI A;  1NXZ A;  2V3K A;  4YQL A;  4YQ5 A;  1TO0 A;  4YQQ A;  4JAL A;  4YQJ A;  3IEF A;  4YQ8 A;  1J85 A;  4YQB A;  4YQP A;  1Z85 A;  4MCD A;  1GZ0 A;  4YVH A;  4RG1 A;  2HA8 A;  4J3C A;  1V2X A;  3BBH A;  4YQ7 A;  3DCM X;  1VHY A;  4YQG A;  1P9P A;  4YQI A;  4YQ1 A;  3G1C A;  4YQD A;  4CNE A;  1UAK A;  1K3R A;  4YQN A;  3SSW N;  3E5Y A;  4JWJ A;  3KW2 A;  4YQA A;  4YQ6 A;  1NS5 A;  3ILK A;  5GMB A;  4CNG A;  3L8U A;  3FRW A;  1O6D A;  1WRS R;  1OY5 A;  4KGN A;  2EGW A;  2I6D A;  4PZK A;  3KNU A;  3AXZ A;  1VH0 A;  1V6Z A;  4YQC A;  4JWF A;  4YQS A;  4FMW A;  4YQ3 A;  3IC6 A;  3GYQ A;  2YY8 A;  4YVG A; 
#chains in the Genus database with same CATH homology
 2QMM A;  3BBE A;  2QWV A;  4YPZ A;  1IPA A;  4FAK A;  3ONP A;  3N4J A;  4H3Z A;  4YPX A;  4JWG A;  3QUV A;  2CX8 A;  3NK6 A;  4YQR A;  3OII A;  4YQ0 A;  3OIN A;  4YQT A;  4YPW A;  5GMC A;  4CNF A;  1MXI A;  4X3L A;  4KDZ A;  4CND A;  1UAJ A;  3KTY A;  5GM8 A;  3O7B A;  1UAM A;  4X3M A;  4YVK A;  3NK7 A;  4YPY A;  4YQ9 A;  2V3J A;  4H3Y A;  2EGV A;  3OIJ A;  4L69 A;  3N4K A;  4XBO A;  4JAK A;  1X7O A;  4IG6 A;  4YQO A;  4YVJ A;  4MCB A;  3AIA A;  3KY7 A;  4MCC A;  1X7P A;  3AI9 X;  1ZJR A;  5CO4 A;  4YQ4 A;  4YVI A;  4YQ2 A;  3BBD A;  2Z0Y A;  4E8B A;  5D9F A;  2O3A A;  1VHK A;  4JWH A;  4YQK A;  5FAI A;  1NXZ A;  2V3K A;  4YQL A;  4YQ5 A;  1TO0 A;  4YQQ A;  4JAL A;  4YQJ A;  3IEF A;  4YQ8 A;  1J85 A;  4YQB A;  4YQP A;  1Z85 A;  4MCD A;  1GZ0 A;  4YVH A;  4RG1 A;  2HA8 A;  4J3C A;  1V2X A;  3BBH A;  4YQ7 A;  3DCM X;  1VHY A;  4YQG A;  1P9P A;  4YQI A;  4YQ1 A;  4YQD A;  4CNE A;  1UAK A;  4YVG A;  1K3R A;  4YQN A;  3E5Y A;  4JWJ A;  3KW2 A;  4YQA A;  4YQ6 A;  1NS5 A;  3ILK A;  5GMB A;  4CNG A;  3L8U A;  1O6D A;  1OY5 A;  4KGN A;  2EGW A;  2I6D A;  4PZK A;  3KNU A;  3AXZ A;  1VH0 A;  1V6Z A;  4YQC A;  4JWF A;  4YQS A;  4FMW A;  4YQ3 A;  3IC6 A;  3GYQ A;  2YY8 A;  1UAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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