4YQ8A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
248
structure length
240
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 70
structure length 240
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq8A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq8A01
4YVHA 4YPZA 3N4KA 5GMBA 4YQLA 2EGVA 1J85A 1UAMA 4X3MA 4KDZA 4H3YA 3AXZA 1X7OA 1UAKA 2I6DA 2EGWA 4YQ5A 4YQ9A 4YPYA 1UALA 5FAIA 2QMMA 2O3AA 4YQ8A 4YQ4A 4YQAA 3GYQA 3NK7A 3OIJA 2V3JA 3BBDA 5GM8A 3L8UA 3OIIA 5D9FA 1IPAA 3KNUA 4FAKA 1VHYA 4KGNA 4YVIA 4YQ1A 4L69A 4YQCA 4YQQA 3AI9X 1Z85A 3DCMX 3BBEA 1V2XA 4YQ2A 1K3RA 1VHKA 2HA8A 4YQ6A 1TO0A 3NK6A 4MCCA 3BBHA 4JAKA 4YQRA 1VH0A 4YQ3A 4YQIA 3E5YA 3KW2A 5CO4A 2CX8A 3OINA 1MXIA 4CNGA 3ONPA 4RG1A 4E8BA 4H3ZA 4YQNA 3KY7A 3KTYA 5GMCA 4YQKA 3IEFA 2V3KA 3IC6A 1NXZA 3QUVA 4JALA 4YPWA 4YQTA 4YQPA 3N4JA 4IG6A 1O6DA 4YQSA 4YQDA 1OY5A 1V6ZA 4MCDA 4CNDA 1GZ0A 4MCBA 3ILKA 4YVGA 4YQGA 4YVJA 4YQ7A 1NS5A 1UAJA 3AIAA 4CNFA 4YQBA 4YQOA 2QWVA 1ZJRA 4CNEA 2Z0YA 4YPXA 4YQJA 4YVKA 4X3LA 1P9PA 3O7BA 4XBOA 4YQ0A 1X7PA 2YY8A 4J3CA 4PZKA
chains in the Genus database with same CATH superfamily
4YVHA 1ZT9A 4YPZA 3N4KA 5GMBA 4YQLA 2EGVA 1J85A 1UAMA 4X3MA 4KDZA 4H3YA 3AXZA 1X7OA 1UAKA 2I6DA 2EGWA 4YQ5A 4YQ9A 4YPYA 1UALA 5FAIA 2QMMA 2O3AA 4YQ8A 4YQ4A 4YQAA 3GYQA 3NK7A 3OIJA 2V3JA 3BBDA 5GM8A 3L8UA 3OIIA 1CO0A 3KORA 5D9FA 1IPAA 3KNUA 4JWFA 4FAKA 1VHYA 4FMWA 4KGNA 4JWJA 4YVIA 4YQ1A 4L69A 1TRRA 4YQCA 4YQQA 2XDIA 3AI9X 1Z85A 3DCMX 3BBEA 3WRPA 1V2XA 4YQ2A 1K3RA 1VHKA 2HA8A 4YQ6A 1TO0A 3NK6A 4MCCA 3BBHA 4JAKA 4YQRA 1VH0A 4YQ3A 4YQIA 3E5YA 3KW2A 5CO4A 2CX8A 3OINA 1MXIA 4CNGA 3ONPA 4RG1A 4E8BA 4H3ZA 4YQNA 3KY7A 3KTYA 5GMCA 4YQKA 3IEFA 2V3KA 1WRSR 3IC6A 1NXZA 3QUVA 4JALA 3G1CA 4YPWA 4YQTA 4YQPA 3N4JA 4IG6A 1O6DA 1RCSA 4YQSA 4YQDA 1OY5A 1V6ZA 1JHGA 4MCDA 1GZ0A 4CNDA 1WRTR 2OZ9R 1WRPR 4MCBA 3ILKA 4YVGA 4YQGA 4YVJA 4YQ7A 4JWGA 3SSWN 1NS5A 1UAJA 3AIAA 4CNFA 4YQBA 4YQOA 2QWVA 1ZJRA 4CNEA 2Z0YA 4YPXA 4YQJA 1MI7R 1TROA 4YVKA 4X3LA 3SSXN 3FRWA 1P9PA 3O7BA 4JWHA 4XBOA 4YQ0A 1X7PA 2YY8A 4J3CA 4PZKA
chains in the Genus database with same CATH topology
4YVHA 4YPZA 3N4KA 5GMBA 4YQLA 2EGVA 1J85A 1UAMA 4X3MA 4KDZA 4H3YA 3AXZA 1X7OA 1UAKA 2I6DA 2EGWA 4YQ5A 4YQ9A 4YPYA 1UALA 5FAIA 2QMMA 2O3AA 4YQ8A 4YQ4A 4YQAA 3GYQA 3NK7A 3OIJA 2V3JA 3BBDA 5GM8A 3L8UA 3OIIA 5D9FA 1IPAA 3KNUA 4JWFA 4FAKA 1VHYA 4FMWA 4KGNA 4JWJA 4YVIA 4YQ1A 4L69A 4YQCA 4YQQA 3AI9X 1Z85A 3DCMX 3BBEA 1V2XA 4YQ2A 1K3RA 1VHKA 2HA8A 4YQ6A 1TO0A 3NK6A 4MCCA 3BBHA 4JAKA 4YQRA 1VH0A 4YQ3A 4YQIA 3E5YA 3KW2A 5CO4A 2CX8A 3OINA 1MXIA 4CNGA 3ONPA 4RG1A 4E8BA 4H3ZA 4YQNA 3KY7A 3KTYA 5GMCA 4YQKA 3IEFA 2V3KA 3IC6A 1NXZA 3QUVA 4JALA 4YPWA 4YQTA 4YQPA 3N4JA 4IG6A 1O6DA 4YQSA 4YQDA 1OY5A 1V6ZA 4MCDA 4CNDA 1GZ0A 4MCBA 3ILKA 4YVGA 4YQGA 4YVJA 4YQ7A 4JWGA 1NS5A 1UAJA 3AIAA 4CNFA 4YQBA 4YQOA 2QWVA 1ZJRA 4CNEA 2Z0YA 4YPXA 4YQJA 4YVKA 4X3LA 1P9PA 3O7BA 4JWHA 4XBOA 4YQ0A 1X7PA 2YY8A 4J3CA 4PZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVH A;  4YPZ A;  3N4K A;  5GMB A;  4YQL A;  2EGV A;  1J85 A;  1UAM A;  4X3M A;  4KDZ A;  4H3Y A;  3AXZ A;  1X7O A;  1UAK A;  2I6D A;  2EGW A;  4YQ5 A;  4YQ9 A;  4YPY A;  1UAL A;  5FAI A;  2QMM A;  2O3A A;  4YQ8 A;  4YQ4 A;  4YQA A;  3GYQ A;  3NK7 A;  3OIJ A;  2V3J A;  3BBD A;  5GM8 A;  3L8U A;  3OII A;  5D9F A;  1IPA A;  3KNU A;  4FAK A;  1VHY A;  4KGN A;  4YVI A;  4YQ1 A;  4L69 A;  4YQC A;  4YQQ A;  3AI9 X;  1Z85 A;  3DCM X;  3BBE A;  1V2X A;  4YQ2 A;  1K3R A;  1VHK A;  2HA8 A;  4YQ6 A;  1TO0 A;  3NK6 A;  4MCC A;  3BBH A;  4JAK A;  4YQR A;  1VH0 A;  4YQ3 A;  4YQI A;  3E5Y A;  3KW2 A;  5CO4 A;  2CX8 A;  3OIN A;  1MXI A;  4CNG A;  3ONP A;  4RG1 A;  4E8B A;  4H3Z A;  4YQN A;  3KY7 A;  3KTY A;  5GMC A;  4YQK A;  3IEF A;  2V3K A;  3IC6 A;  1NXZ A;  3QUV A;  4JAL A;  4YPW A;  4YQT A;  4YQP A;  3N4J A;  4IG6 A;  1O6D A;  4YQS A;  4YQD A;  1OY5 A;  1V6Z A;  4MCD A;  4CND A;  1GZ0 A;  4MCB A;  3ILK A;  4YVG A;  4YQG A;  4YVJ A;  4YQ7 A;  1NS5 A;  1UAJ A;  3AIA A;  4CNF A;  4YQB A;  4YQO A;  2QWV A;  1ZJR A;  4CNE A;  2Z0Y A;  4YPX A;  4YQJ A;  4YVK A;  4X3L A;  1P9P A;  3O7B A;  4XBO A;  4YQ0 A;  1X7P A;  2YY8 A;  4J3C A;  4PZK A; 
#chains in the Genus database with same CATH topology
 4YVH A;  1ZT9 A;  4YPZ A;  3N4K A;  5GMB A;  4YQL A;  2EGV A;  1J85 A;  1UAM A;  4X3M A;  4KDZ A;  4H3Y A;  3AXZ A;  1X7O A;  1UAK A;  2I6D A;  2EGW A;  4YQ5 A;  4YQ9 A;  4YPY A;  1UAL A;  5FAI A;  2QMM A;  2O3A A;  4YQ8 A;  4YQ4 A;  4YQA A;  3GYQ A;  3NK7 A;  3OIJ A;  2V3J A;  3BBD A;  5GM8 A;  3L8U A;  3OII A;  1CO0 A;  3KOR A;  5D9F A;  1IPA A;  3KNU A;  4JWF A;  4FAK A;  1VHY A;  4FMW A;  4KGN A;  4JWJ A;  4YVI A;  4YQ1 A;  4L69 A;  1TRR A;  4YQC A;  4YQQ A;  2XDI A;  3AI9 X;  1Z85 A;  3DCM X;  3BBE A;  3WRP A;  1V2X A;  4YQ2 A;  1K3R A;  1VHK A;  2HA8 A;  4YQ6 A;  1TO0 A;  3NK6 A;  4MCC A;  3BBH A;  4JAK A;  4YQR A;  1VH0 A;  4YQ3 A;  4YQI A;  3E5Y A;  3KW2 A;  5CO4 A;  2CX8 A;  3OIN A;  1MXI A;  4CNG A;  3ONP A;  4RG1 A;  4E8B A;  4H3Z A;  4YQN A;  3KY7 A;  3KTY A;  5GMC A;  4YQK A;  3IEF A;  2V3K A;  1WRS R;  3IC6 A;  1NXZ A;  3QUV A;  4JAL A;  3G1C A;  4YPW A;  4YQT A;  4YQP A;  3N4J A;  4IG6 A;  1O6D A;  1RCS A;  4YQS A;  4YQD A;  1OY5 A;  1V6Z A;  1JHG A;  4MCD A;  1GZ0 A;  4CND A;  1WRT R;  2OZ9 R;  1WRP R;  4MCB A;  3ILK A;  4YVG A;  4YQG A;  4YVJ A;  4YQ7 A;  4JWG A;  3SSW N;  1NS5 A;  1UAJ A;  3AIA A;  4CNF A;  4YQB A;  4YQO A;  2QWV A;  1ZJR A;  4CNE A;  2Z0Y A;  4YPX A;  4YQJ A;  1MI7 R;  1TRO A;  4YVK A;  4X3L A;  3SSX N;  3FRW A;  1P9P A;  3O7B A;  4JWH A;  4XBO A;  4YQ0 A;  1X7P A;  2YY8 A;  4J3C A;  4PZK A; 
#chains in the Genus database with same CATH homology
 4YVH A;  4YPZ A;  3N4K A;  5GMB A;  4YQL A;  2EGV A;  1J85 A;  1UAM A;  4X3M A;  4KDZ A;  4H3Y A;  3AXZ A;  1X7O A;  1UAK A;  2I6D A;  2EGW A;  4YQ5 A;  4YQ9 A;  4YPY A;  1UAL A;  5FAI A;  2QMM A;  2O3A A;  4YQ8 A;  4YQ4 A;  4YQA A;  3GYQ A;  3NK7 A;  3OIJ A;  2V3J A;  3BBD A;  5GM8 A;  3L8U A;  3OII A;  5D9F A;  1IPA A;  3KNU A;  4JWF A;  4FAK A;  1VHY A;  4FMW A;  4KGN A;  4JWJ A;  4YVI A;  4YQ1 A;  4L69 A;  4YQC A;  4YQQ A;  3AI9 X;  1Z85 A;  3DCM X;  3BBE A;  1V2X A;  4YQ2 A;  1K3R A;  1VHK A;  2HA8 A;  4YQ6 A;  1TO0 A;  3NK6 A;  4MCC A;  3BBH A;  4JAK A;  4YQR A;  1VH0 A;  4YQ3 A;  4YQI A;  3E5Y A;  3KW2 A;  5CO4 A;  2CX8 A;  3OIN A;  1MXI A;  4CNG A;  3ONP A;  4RG1 A;  4E8B A;  4H3Z A;  4YQN A;  3KY7 A;  3KTY A;  5GMC A;  4YQK A;  3IEF A;  2V3K A;  3IC6 A;  1NXZ A;  3QUV A;  4JAL A;  4YPW A;  4YQT A;  4YQP A;  3N4J A;  4IG6 A;  1O6D A;  4YQS A;  4YQD A;  1OY5 A;  1V6Z A;  4MCD A;  4CND A;  1GZ0 A;  4MCB A;  3ILK A;  4YVG A;  4YQG A;  4YVJ A;  4YQ7 A;  4JWG A;  1NS5 A;  1UAJ A;  3AIA A;  4CNF A;  4YQB A;  4YQO A;  2QWV A;  1ZJR A;  4CNE A;  2Z0Y A;  4YPX A;  4YQJ A;  4YVK A;  4X3L A;  1P9P A;  3O7B A;  4JWH A;  4XBO A;  4YQ0 A;  1X7P A;  2YY8 A;  4J3C A;  4PZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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