4YQ9A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
253
structure length
245
Chain Sequence
LVPRGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 77
structure length 245
sequence length 253
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq9A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq9A01
4YQ7A 2YY8A 4JAKA 4YQ5A 3OINA 3AI9X 1OY5A 4YQKA 4YPZA 3ILKA 5FAIA 2QWVA 4YQNA 5GMCA 4KDZA 4YQ8A 2QMMA 4IG6A 1UAJA 5CO4A 4YVJA 3O7BA 3QUVA 3N4JA 4MCBA 3NK6A 4YVGA 2CX8A 3KTYA 1MXIA 2V3KA 4KGNA 1K3RA 4JALA 4YQBA 3KY7A 4H3ZA 2Z0YA 4YQ0A 3BBDA 1ZJRA 4XBOA 3KW2A 4MCCA 4CNDA 2EGWA 1VHYA 4PZKA 4H3YA 3OIIA 1Z85A 4YQ3A 2I6DA 4YVIA 4E8BA 4YQ4A 1P9PA 4YQ9A 1J85A 1X7PA 1UAMA 4X3LA 3DCMX 4CNGA 4YPXA 4YQCA 4YQLA 1V6ZA 4YQ2A 1NXZA 4X3MA 5GMBA 1TO0A 4YQQA 5GM8A 4YQPA 4YQIA 1UALA 3BBEA 4YQRA 2HA8A 3BBHA 4YQAA 1IPAA 4YVKA 1V2XA 3ONPA 4YQJA 1VHKA 1UAKA 3IEFA 2O3AA 3E5YA 4J3CA 4YQSA 4YVHA 4YPWA 4YQOA 3AIAA 2V3JA 3L8UA 4CNFA 1NS5A 3NK7A 1X7OA 4YQGA 1VH0A 3IC6A 4YQ6A 1GZ0A 4RG1A 5D9FA 3OIJA 4YQ1A 3GYQA 4YQTA 4CNEA 4FAKA 3N4KA 4YQDA 3KNUA 2EGVA 1O6DA 4MCDA 3AXZA 4L69A 4YPYA
chains in the Genus database with same CATH superfamily
4YQ7A 2YY8A 4JAKA 4YQ5A 3OINA 3AI9X 1OY5A 4YQKA 4YPZA 3ILKA 5FAIA 2QWVA 4JWJA 4YQNA 5GMCA 4KDZA 4YQ8A 2QMMA 4IG6A 3SSXN 1UAJA 5CO4A 4YVJA 3O7BA 3QUVA 3N4JA 4MCBA 3NK6A 4YVGA 2CX8A 1TROA 3KTYA 4JWFA 1MXIA 2OZ9R 1ZT9A 1TRRA 2V3KA 4KGNA 1K3RA 4JALA 2XDIA 4YQBA 3KY7A 4H3ZA 2Z0YA 4YQ0A 3BBDA 1ZJRA 4XBOA 3KW2A 4MCCA 4CNDA 3FRWA 4JWGA 2EGWA 1VHYA 4PZKA 4H3YA 3OIIA 1Z85A 4YQ3A 2I6DA 4YVIA 4E8BA 3WRPA 4YQ4A 1P9PA 4YQ9A 1J85A 1X7PA 1UAMA 4X3LA 3DCMX 4FMWA 1CO0A 4CNGA 4YPXA 4YQCA 4YQLA 1V6ZA 4YQ2A 1NXZA 4X3MA 5GMBA 1TO0A 3KORA 4YQQA 5GM8A 4YQPA 4YQIA 1UALA 1JHGA 3BBEA 4YQRA 2HA8A 3BBHA 4YQAA 1IPAA 3SSWN 4YVKA 1V2XA 1MI7R 3ONPA 4YQJA 1UAKA 1VHKA 3IEFA 2O3AA 3E5YA 4J3CA 3G1CA 4YQSA 4YVHA 4YPWA 4YQOA 3AIAA 4JWHA 2V3JA 1WRTR 3L8UA 4CNFA 1RCSA 1NS5A 3NK7A 1X7OA 4YQGA 1VH0A 3IC6A 1WRSR 4YQ6A 1GZ0A 4RG1A 5D9FA 3OIJA 4YQ1A 3GYQA 4YQTA 4CNEA 4FAKA 3N4KA 4YQDA 3KNUA 2EGVA 1WRPR 1O6DA 4MCDA 3AXZA 4L69A 4YPYA
chains in the Genus database with same CATH topology
4YQ7A 2YY8A 4JAKA 4YQ5A 3OINA 3AI9X 1OY5A 4YQKA 4YPZA 3ILKA 5FAIA 2QWVA 4JWJA 4YQNA 5GMCA 4KDZA 4YQ8A 2QMMA 4IG6A 1UAJA 5CO4A 4YVJA 3O7BA 3QUVA 3N4JA 4MCBA 3NK6A 4YVGA 2CX8A 3KTYA 4JWFA 1MXIA 2V3KA 4KGNA 1K3RA 4JALA 4YQBA 3KY7A 4H3ZA 2Z0YA 4YQ0A 3BBDA 1ZJRA 4XBOA 3KW2A 4MCCA 4CNDA 4JWGA 2EGWA 1VHYA 4PZKA 4H3YA 3OIIA 1Z85A 4YQ3A 2I6DA 4YVIA 4E8BA 4YQ4A 1P9PA 4YQ9A 1J85A 1X7PA 1UAMA 4X3LA 3DCMX 4FMWA 4CNGA 4YPXA 4YQCA 4YQLA 1V6ZA 4YQ2A 1NXZA 4X3MA 5GMBA 1TO0A 4YQQA 5GM8A 4YQPA 4YQIA 1UALA 3BBEA 4YQRA 2HA8A 3BBHA 4YQAA 1IPAA 4YVKA 1V2XA 3ONPA 4YQJA 1VHKA 1UAKA 3IEFA 2O3AA 3E5YA 4J3CA 4YQSA 4YVHA 4YPWA 4YQOA 3AIAA 4JWHA 2V3JA 3L8UA 4CNFA 1NS5A 3NK7A 1X7OA 4YQGA 1VH0A 3IC6A 4YQ6A 1GZ0A 4RG1A 5D9FA 3OIJA 4YQ1A 3GYQA 4YQTA 4CNEA 4FAKA 3N4KA 4YQDA 3KNUA 2EGVA 1O6DA 4MCDA 3AXZA 4L69A 4YPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ7 A;  2YY8 A;  4JAK A;  4YQ5 A;  3OIN A;  3AI9 X;  1OY5 A;  4YQK A;  4YPZ A;  3ILK A;  5FAI A;  2QWV A;  4YQN A;  5GMC A;  4KDZ A;  4YQ8 A;  2QMM A;  4IG6 A;  1UAJ A;  5CO4 A;  4YVJ A;  3O7B A;  3QUV A;  3N4J A;  4MCB A;  3NK6 A;  4YVG A;  2CX8 A;  3KTY A;  1MXI A;  2V3K A;  4KGN A;  1K3R A;  4JAL A;  4YQB A;  3KY7 A;  4H3Z A;  2Z0Y A;  4YQ0 A;  3BBD A;  1ZJR A;  4XBO A;  3KW2 A;  4MCC A;  4CND A;  2EGW A;  1VHY A;  4PZK A;  4H3Y A;  3OII A;  1Z85 A;  4YQ3 A;  2I6D A;  4YVI A;  4E8B A;  4YQ4 A;  1P9P A;  4YQ9 A;  1J85 A;  1X7P A;  1UAM A;  4X3L A;  3DCM X;  4CNG A;  4YPX A;  4YQC A;  4YQL A;  1V6Z A;  4YQ2 A;  1NXZ A;  4X3M A;  5GMB A;  1TO0 A;  4YQQ A;  5GM8 A;  4YQP A;  4YQI A;  1UAL A;  3BBE A;  4YQR A;  2HA8 A;  3BBH A;  4YQA A;  1IPA A;  4YVK A;  1V2X A;  3ONP A;  4YQJ A;  1VHK A;  1UAK A;  3IEF A;  2O3A A;  3E5Y A;  4J3C A;  4YQS A;  4YVH A;  4YPW A;  4YQO A;  3AIA A;  2V3J A;  3L8U A;  4CNF A;  1NS5 A;  3NK7 A;  1X7O A;  4YQG A;  1VH0 A;  3IC6 A;  4YQ6 A;  1GZ0 A;  4RG1 A;  5D9F A;  3OIJ A;  4YQ1 A;  3GYQ A;  4YQT A;  4CNE A;  4FAK A;  3N4K A;  4YQD A;  3KNU A;  2EGV A;  1O6D A;  4MCD A;  3AXZ A;  4L69 A;  4YPY A; 
#chains in the Genus database with same CATH topology
 4YQ7 A;  2YY8 A;  4JAK A;  4YQ5 A;  3OIN A;  3AI9 X;  1OY5 A;  4YQK A;  4YPZ A;  3ILK A;  5FAI A;  2QWV A;  4JWJ A;  4YQN A;  5GMC A;  4KDZ A;  4YQ8 A;  2QMM A;  4IG6 A;  3SSX N;  1UAJ A;  5CO4 A;  4YVJ A;  3O7B A;  3QUV A;  3N4J A;  4MCB A;  3NK6 A;  4YVG A;  2CX8 A;  1TRO A;  3KTY A;  4JWF A;  1MXI A;  2OZ9 R;  1ZT9 A;  1TRR A;  2V3K A;  4KGN A;  1K3R A;  4JAL A;  2XDI A;  4YQB A;  3KY7 A;  4H3Z A;  2Z0Y A;  4YQ0 A;  3BBD A;  1ZJR A;  4XBO A;  3KW2 A;  4MCC A;  4CND A;  3FRW A;  4JWG A;  2EGW A;  1VHY A;  4PZK A;  4H3Y A;  3OII A;  1Z85 A;  4YQ3 A;  2I6D A;  4YVI A;  4E8B A;  3WRP A;  4YQ4 A;  1P9P A;  4YQ9 A;  1J85 A;  1X7P A;  1UAM A;  4X3L A;  3DCM X;  4FMW A;  1CO0 A;  4CNG A;  4YPX A;  4YQC A;  4YQL A;  1V6Z A;  4YQ2 A;  1NXZ A;  4X3M A;  5GMB A;  1TO0 A;  3KOR A;  4YQQ A;  5GM8 A;  4YQP A;  4YQI A;  1UAL A;  1JHG A;  3BBE A;  4YQR A;  2HA8 A;  3BBH A;  4YQA A;  1IPA A;  3SSW N;  4YVK A;  1V2X A;  1MI7 R;  3ONP A;  4YQJ A;  1UAK A;  1VHK A;  3IEF A;  2O3A A;  3E5Y A;  4J3C A;  3G1C A;  4YQS A;  4YVH A;  4YPW A;  4YQO A;  3AIA A;  4JWH A;  2V3J A;  1WRT R;  3L8U A;  4CNF A;  1RCS A;  1NS5 A;  3NK7 A;  1X7O A;  4YQG A;  1VH0 A;  3IC6 A;  1WRS R;  4YQ6 A;  1GZ0 A;  4RG1 A;  5D9F A;  3OIJ A;  4YQ1 A;  3GYQ A;  4YQT A;  4CNE A;  4FAK A;  3N4K A;  4YQD A;  3KNU A;  2EGV A;  1WRP R;  1O6D A;  4MCD A;  3AXZ A;  4L69 A;  4YPY A; 
#chains in the Genus database with same CATH homology
 4YQ7 A;  2YY8 A;  4JAK A;  4YQ5 A;  3OIN A;  3AI9 X;  1OY5 A;  4YQK A;  4YPZ A;  3ILK A;  5FAI A;  2QWV A;  4JWJ A;  4YQN A;  5GMC A;  4KDZ A;  4YQ8 A;  2QMM A;  4IG6 A;  1UAJ A;  5CO4 A;  4YVJ A;  3O7B A;  3QUV A;  3N4J A;  4MCB A;  3NK6 A;  4YVG A;  2CX8 A;  3KTY A;  4JWF A;  1MXI A;  2V3K A;  4KGN A;  1K3R A;  4JAL A;  4YQB A;  3KY7 A;  4H3Z A;  2Z0Y A;  4YQ0 A;  3BBD A;  1ZJR A;  4XBO A;  3KW2 A;  4MCC A;  4CND A;  4JWG A;  2EGW A;  1VHY A;  4PZK A;  4H3Y A;  3OII A;  1Z85 A;  4YQ3 A;  2I6D A;  4YVI A;  4E8B A;  4YQ4 A;  1P9P A;  4YQ9 A;  1J85 A;  1X7P A;  1UAM A;  4X3L A;  3DCM X;  4FMW A;  4CNG A;  4YPX A;  4YQC A;  4YQL A;  1V6Z A;  4YQ2 A;  1NXZ A;  4X3M A;  5GMB A;  1TO0 A;  4YQQ A;  5GM8 A;  4YQP A;  4YQI A;  1UAL A;  3BBE A;  4YQR A;  2HA8 A;  3BBH A;  4YQA A;  1IPA A;  4YVK A;  1V2X A;  3ONP A;  4YQJ A;  1VHK A;  1UAK A;  3IEF A;  2O3A A;  3E5Y A;  4J3C A;  4YQS A;  4YVH A;  4YPW A;  4YQO A;  3AIA A;  4JWH A;  2V3J A;  3L8U A;  4CNF A;  1NS5 A;  3NK7 A;  1X7O A;  4YQG A;  1VH0 A;  3IC6 A;  4YQ6 A;  1GZ0 A;  4RG1 A;  5D9F A;  3OIJ A;  4YQ1 A;  3GYQ A;  4YQT A;  4CNE A;  4FAK A;  3N4K A;  4YQD A;  3KNU A;  2EGV A;  1O6D A;  4MCD A;  3AXZ A;  4L69 A;  4YPY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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