4YQAA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
248
structure length
237
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 72
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqaA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqaA01
4YQDA 3O7BA 4JAKA 1GZ0A 4FAKA 1UALA 1NS5A 1K3RA 1OY5A 4MCDA 5FAIA 3OINA 1J85A 4IG6A 1NXZA 3NK7A 4YQ6A 4YQTA 1MXIA 3E5YA 4CNDA 3KTYA 1V6ZA 3OIIA 5D9FA 4XBOA 4YQGA 3KY7A 4YVHA 4YQKA 4MCBA 5GMBA 4YQIA 4YQQA 1UAJA 4H3YA 3AIAA 2CX8A 4YPWA 5GM8A 4YPXA 2QWVA 3AI9X 4H3ZA 1VHYA 4YQ1A 2V3JA 3DCMX 4YVGA 3ONPA 1TO0A 4YQLA 4YQ8A 4YPZA 4E8BA 3L8UA 4YQCA 4YQ2A 3KW2A 4KDZA 1O6DA 2EGWA 4X3MA 3KNUA 4YVKA 4YQRA 4YQJA 4J3CA 4YQBA 1UAMA 2Z0YA 3AXZA 1ZJRA 4CNFA 3IC6A 4RG1A 4YQNA 3NK6A 3ILKA 5CO4A 4CNGA 3GYQA 4YQ7A 4PZKA 5GMCA 4JALA 4YQPA 4YQ3A 3OIJA 1Z85A 4MCCA 4X3LA 2EGVA 3QUVA 4YQ4A 4YQ9A 1VHKA 3BBHA 4YQSA 4YQAA 4YQ0A 1VH0A 1P9PA 3N4JA 2I6DA 4YPYA 3BBEA 2O3AA 4YVIA 1X7PA 4CNEA 1IPAA 3BBDA 3N4KA 1V2XA 1X7OA 4YVJA 1UAKA 4KGNA 2YY8A 4L69A 2HA8A 2QMMA 4YQ5A 2V3KA 3IEFA 4YQOA
chains in the Genus database with same CATH superfamily
4YQDA 3O7BA 4JAKA 4JWGA 1GZ0A 4FAKA 1UALA 3SSWN 1NS5A 1K3RA 1OY5A 4MCDA 5FAIA 3OINA 1J85A 4IG6A 1NXZA 3NK7A 4YQ6A 4YQTA 1MXIA 3E5YA 4CNDA 4JWFA 4YQOA 3KTYA 1V6ZA 3OIIA 5D9FA 4JWHA 4XBOA 4YQGA 3G1CA 3KY7A 3KORA 4YVHA 4YQKA 4MCBA 5GMBA 1WRSR 4YQIA 4YQQA 1UAJA 4H3YA 3AIAA 1CO0A 2CX8A 4YPWA 5GM8A 4YPXA 2QWVA 3AI9X 4H3ZA 1VHYA 4YQ1A 2V3JA 3DCMX 4YVGA 3ONPA 1TO0A 1WRPR 4YQLA 4YQ8A 4YPZA 4E8BA 3L8UA 1TRRA 4YQCA 4YQ2A 3KW2A 3FRWA 4KDZA 1O6DA 2EGWA 1WRTR 4X3MA 3KNUA 4YVKA 4YQRA 4J3CA 4YQBA 1UAMA 2Z0YA 3AXZA 1ZJRA 1MI7R 4CNFA 2XDIA 3IC6A 4RG1A 4YQNA 3NK6A 3ILKA 5CO4A 4FMWA 4CNGA 3GYQA 4YQ7A 4PZKA 5GMCA 4JALA 4YQPA 4JWJA 4YQ3A 3OIJA 4MCCA 1Z85A 4X3LA 2EGVA 1TROA 3QUVA 2OZ9R 4YQ4A 4YQ9A 1VHKA 3BBHA 4YQSA 4YQAA 4YQ0A 1VH0A 1P9PA 3SSXN 3N4JA 2I6DA 4YPYA 3BBEA 2O3AA 3WRPA 4YVIA 1X7PA 4CNEA 1IPAA 3BBDA 3N4KA 1V2XA 1X7OA 4YVJA 1UAKA 1RCSA 4KGNA 2YY8A 4L69A 2HA8A 1ZT9A 2QMMA 1JHGA 4YQ5A 2V3KA 3IEFA 4YQJA
chains in the Genus database with same CATH topology
4YQDA 3O7BA 4JAKA 4JWGA 1GZ0A 4FAKA 1UALA 1NS5A 1K3RA 1OY5A 4MCDA 5FAIA 3OINA 1J85A 4IG6A 1NXZA 3NK7A 4YQ6A 4YQTA 1MXIA 3E5YA 4CNDA 4JWFA 3KTYA 1V6ZA 3OIIA 5D9FA 4JWHA 4XBOA 4YQGA 3KY7A 4YVHA 4YQKA 4MCBA 5GMBA 4YQIA 4YQQA 1UAJA 4H3YA 3AIAA 2CX8A 4YPWA 5GM8A 4YPXA 2QWVA 3AI9X 4H3ZA 1VHYA 4YQ1A 2V3JA 3DCMX 4YVGA 3ONPA 1TO0A 4YQLA 4YQ8A 4YPZA 4E8BA 3L8UA 4YQCA 4YQ2A 3KW2A 4KDZA 1O6DA 2EGWA 4X3MA 3KNUA 4YVKA 4YQRA 4YQJA 4J3CA 4YQBA 1UAMA 2Z0YA 3AXZA 1ZJRA 4CNFA 3IC6A 4RG1A 4YQNA 3NK6A 3ILKA 5CO4A 4FMWA 4CNGA 3GYQA 4YQ7A 4PZKA 5GMCA 4JALA 4YQPA 4JWJA 4YQ3A 3OIJA 1Z85A 4MCCA 4X3LA 2EGVA 3QUVA 4YQ4A 4YQ9A 1VHKA 3BBHA 4YQSA 4YQAA 4YQ0A 1VH0A 1P9PA 3N4JA 2I6DA 4YPYA 3BBEA 2O3AA 4YVIA 1X7PA 4CNEA 1IPAA 3BBDA 3N4KA 1V2XA 1X7OA 4YVJA 1UAKA 4KGNA 2YY8A 4L69A 2HA8A 2QMMA 4YQ5A 2V3KA 3IEFA 4YQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQD A;  3O7B A;  4JAK A;  1GZ0 A;  4FAK A;  1UAL A;  1NS5 A;  1K3R A;  1OY5 A;  4MCD A;  5FAI A;  3OIN A;  1J85 A;  4IG6 A;  1NXZ A;  3NK7 A;  4YQ6 A;  4YQT A;  1MXI A;  3E5Y A;  4CND A;  3KTY A;  1V6Z A;  3OII A;  5D9F A;  4XBO A;  4YQG A;  3KY7 A;  4YVH A;  4YQK A;  4MCB A;  5GMB A;  4YQI A;  4YQQ A;  1UAJ A;  4H3Y A;  3AIA A;  2CX8 A;  4YPW A;  5GM8 A;  4YPX A;  2QWV A;  3AI9 X;  4H3Z A;  1VHY A;  4YQ1 A;  2V3J A;  3DCM X;  4YVG A;  3ONP A;  1TO0 A;  4YQL A;  4YQ8 A;  4YPZ A;  4E8B A;  3L8U A;  4YQC A;  4YQ2 A;  3KW2 A;  4KDZ A;  1O6D A;  2EGW A;  4X3M A;  3KNU A;  4YVK A;  4YQR A;  4YQJ A;  4J3C A;  4YQB A;  1UAM A;  2Z0Y A;  3AXZ A;  1ZJR A;  4CNF A;  3IC6 A;  4RG1 A;  4YQN A;  3NK6 A;  3ILK A;  5CO4 A;  4CNG A;  3GYQ A;  4YQ7 A;  4PZK A;  5GMC A;  4JAL A;  4YQP A;  4YQ3 A;  3OIJ A;  1Z85 A;  4MCC A;  4X3L A;  2EGV A;  3QUV A;  4YQ4 A;  4YQ9 A;  1VHK A;  3BBH A;  4YQS A;  4YQA A;  4YQ0 A;  1VH0 A;  1P9P A;  3N4J A;  2I6D A;  4YPY A;  3BBE A;  2O3A A;  4YVI A;  1X7P A;  4CNE A;  1IPA A;  3BBD A;  3N4K A;  1V2X A;  1X7O A;  4YVJ A;  1UAK A;  4KGN A;  2YY8 A;  4L69 A;  2HA8 A;  2QMM A;  4YQ5 A;  2V3K A;  3IEF A;  4YQO A; 
#chains in the Genus database with same CATH topology
 4YQD A;  3O7B A;  4JAK A;  4JWG A;  1GZ0 A;  4FAK A;  1UAL A;  3SSW N;  1NS5 A;  1K3R A;  1OY5 A;  4MCD A;  5FAI A;  3OIN A;  1J85 A;  4IG6 A;  1NXZ A;  3NK7 A;  4YQ6 A;  4YQT A;  1MXI A;  3E5Y A;  4CND A;  4JWF A;  4YQO A;  3KTY A;  1V6Z A;  3OII A;  5D9F A;  4JWH A;  4XBO A;  4YQG A;  3G1C A;  3KY7 A;  3KOR A;  4YVH A;  4YQK A;  4MCB A;  5GMB A;  1WRS R;  4YQI A;  4YQQ A;  1UAJ A;  4H3Y A;  3AIA A;  1CO0 A;  2CX8 A;  4YPW A;  5GM8 A;  4YPX A;  2QWV A;  3AI9 X;  4H3Z A;  1VHY A;  4YQ1 A;  2V3J A;  3DCM X;  4YVG A;  3ONP A;  1TO0 A;  1WRP R;  4YQL A;  4YQ8 A;  4YPZ A;  4E8B A;  3L8U A;  1TRR A;  4YQC A;  4YQ2 A;  3KW2 A;  3FRW A;  4KDZ A;  1O6D A;  2EGW A;  1WRT R;  4X3M A;  3KNU A;  4YVK A;  4YQR A;  4J3C A;  4YQB A;  1UAM A;  2Z0Y A;  3AXZ A;  1ZJR A;  1MI7 R;  4CNF A;  2XDI A;  3IC6 A;  4RG1 A;  4YQN A;  3NK6 A;  3ILK A;  5CO4 A;  4FMW A;  4CNG A;  3GYQ A;  4YQ7 A;  4PZK A;  5GMC A;  4JAL A;  4YQP A;  4JWJ A;  4YQ3 A;  3OIJ A;  4MCC A;  1Z85 A;  4X3L A;  2EGV A;  1TRO A;  3QUV A;  2OZ9 R;  4YQ4 A;  4YQ9 A;  1VHK A;  3BBH A;  4YQS A;  4YQA A;  4YQ0 A;  1VH0 A;  1P9P A;  3SSX N;  3N4J A;  2I6D A;  4YPY A;  3BBE A;  2O3A A;  3WRP A;  4YVI A;  1X7P A;  4CNE A;  1IPA A;  3BBD A;  3N4K A;  1V2X A;  1X7O A;  4YVJ A;  1UAK A;  1RCS A;  4KGN A;  2YY8 A;  4L69 A;  2HA8 A;  1ZT9 A;  2QMM A;  1JHG A;  4YQ5 A;  2V3K A;  3IEF A;  4YQJ A; 
#chains in the Genus database with same CATH homology
 4YQD A;  3O7B A;  4JAK A;  4JWG A;  1GZ0 A;  4FAK A;  1UAL A;  1NS5 A;  1K3R A;  1OY5 A;  4MCD A;  5FAI A;  3OIN A;  1J85 A;  4IG6 A;  1NXZ A;  3NK7 A;  4YQ6 A;  4YQT A;  1MXI A;  3E5Y A;  4CND A;  4JWF A;  3KTY A;  1V6Z A;  3OII A;  5D9F A;  4JWH A;  4XBO A;  4YQG A;  3KY7 A;  4YVH A;  4YQK A;  4MCB A;  5GMB A;  4YQI A;  4YQQ A;  1UAJ A;  4H3Y A;  3AIA A;  2CX8 A;  4YPW A;  5GM8 A;  4YPX A;  2QWV A;  3AI9 X;  4H3Z A;  1VHY A;  4YQ1 A;  2V3J A;  3DCM X;  4YVG A;  3ONP A;  1TO0 A;  4YQL A;  4YQ8 A;  4YPZ A;  4E8B A;  3L8U A;  4YQC A;  4YQ2 A;  3KW2 A;  4KDZ A;  1O6D A;  2EGW A;  4X3M A;  3KNU A;  4YVK A;  4YQR A;  4YQJ A;  4J3C A;  4YQB A;  1UAM A;  2Z0Y A;  3AXZ A;  1ZJR A;  4CNF A;  3IC6 A;  4RG1 A;  4YQN A;  3NK6 A;  3ILK A;  5CO4 A;  4FMW A;  4CNG A;  3GYQ A;  4YQ7 A;  4PZK A;  5GMC A;  4JAL A;  4YQP A;  4JWJ A;  4YQ3 A;  3OIJ A;  1Z85 A;  4MCC A;  4X3L A;  2EGV A;  3QUV A;  4YQ4 A;  4YQ9 A;  1VHK A;  3BBH A;  4YQS A;  4YQA A;  4YQ0 A;  1VH0 A;  1P9P A;  3N4J A;  2I6D A;  4YPY A;  3BBE A;  2O3A A;  4YVI A;  1X7P A;  4CNE A;  1IPA A;  3BBD A;  3N4K A;  1V2X A;  1X7O A;  4YVJ A;  1UAK A;  4KGN A;  2YY8 A;  4L69 A;  2HA8 A;  2QMM A;  4YQ5 A;  2V3K A;  3IEF A;  4YQO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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