4YQBA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
248
structure length
240
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 72
structure length 240
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqbA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqbA01
1O6DA 4YQ8A 4YVKA 4YPXA 3AI9X 3OIJA 4YPZA 3KY7A 4MCBA 4YQJA 4JALA 4RG1A 4YQ4A 1P9PA 2EGWA 4YQGA 4YQSA 4JAKA 2O3AA 2QWVA 1X7OA 3IC6A 4YQTA 4YQNA 3ONPA 5CO4A 4CNGA 5D9FA 4YPWA 1VHKA 4XBOA 4YQLA 4J3CA 4L69A 2I6DA 4YVIA 4YQ5A 3E5YA 3NK7A 1OY5A 4KDZA 2YY8A 2QMMA 4YQDA 3BBDA 4YQRA 3KTYA 2V3KA 4YQ2A 4YQ1A 4MCCA 3OIIA 3KW2A 1UAKA 3O7BA 1Z85A 1J85A 4CNDA 1K3RA 3IEFA 5GMCA 4IG6A 1MXIA 4YQIA 4KGNA 1ZJRA 4YVHA 4YQKA 2Z0YA 1X7PA 3QUVA 2V3JA 4YQ9A 4X3LA 1V2XA 4H3YA 3ILKA 4YQOA 4YQBA 3AIAA 4CNEA 1UAMA 3NK6A 4YQCA 2EGVA 5GM8A 2CX8A 4MCDA 4X3MA 4YQQA 1NS5A 3AXZA 2HA8A 4YQ3A 1NXZA 4FAKA 4YVGA 3N4JA 1IPAA 3BBHA 1UAJA 1V6ZA 4YQPA 3L8UA 1TO0A 4YQ0A 3BBEA 3DCMX 4YQ6A 1GZ0A 4H3ZA 3KNUA 4YPYA 4E8BA 1VHYA 1VH0A 4YVJA 4CNFA 5FAIA 4YQ7A 4PZKA 5GMBA 1UALA 3N4KA 3OINA 3GYQA 4YQAA
chains in the Genus database with same CATH superfamily
1O6DA 4YQ8A 4YVKA 4YPXA 3AI9X 3OIJA 4YPZA 3KY7A 4MCBA 4JWJA 4YQJA 4JALA 1WRSR 4RG1A 4YQ4A 1P9PA 2EGWA 4YQGA 4YQSA 4JAKA 2O3AA 2QWVA 1X7OA 3IC6A 1WRTR 4YQTA 4YQNA 3ONPA 5CO4A 4CNGA 5D9FA 4YPWA 1VHKA 4XBOA 4YQLA 2OZ9R 4J3CA 4L69A 2I6DA 4YVIA 4YQ5A 3E5YA 3NK7A 1WRPR 1OY5A 4KDZA 2YY8A 2QMMA 4YQDA 3BBDA 4YQRA 3KTYA 2V3KA 4YQ2A 4YQ1A 4MCCA 3OIIA 3KW2A 2XDIA 1RCSA 1UAKA 3O7BA 1Z85A 1J85A 4CNDA 1K3RA 1CO0A 3IEFA 5GMCA 4IG6A 1MXIA 3G1CA 4YQIA 4KGNA 1ZJRA 4YVHA 4YQKA 2Z0YA 1X7PA 3QUVA 3SSWN 2V3JA 3KORA 1ZT9A 4YQ9A 4X3LA 1V2XA 4H3YA 3SSXN 3ILKA 4YQOA 4YQBA 1MI7R 1TRRA 3AIAA 4CNEA 1UAMA 3NK6A 4YQCA 3FRWA 2EGVA 5GM8A 2CX8A 4MCDA 4X3MA 4YQQA 1TROA 1NS5A 3AXZA 4JWFA 2HA8A 1JHGA 4JWGA 4YQ3A 1NXZA 4FAKA 4FMWA 4YVGA 3N4JA 1IPAA 3BBHA 1UAJA 3WRPA 1V6ZA 4YQPA 3L8UA 1TO0A 4YQ0A 3BBEA 3DCMX 4YQ6A 1GZ0A 4H3ZA 3KNUA 4YPYA 4E8BA 1VHYA 1VH0A 4YVJA 4JWHA 4CNFA 5FAIA 4YQ7A 4PZKA 5GMBA 1UALA 3N4KA 3OINA 3GYQA 4YQAA
chains in the Genus database with same CATH topology
1O6DA 4YQ8A 4YVKA 4YPXA 3AI9X 3OIJA 4YPZA 3KY7A 4MCBA 4JWJA 4YQJA 4JALA 4RG1A 4YQ4A 1P9PA 2EGWA 4YQGA 4YQSA 4JAKA 2O3AA 2QWVA 1X7OA 3IC6A 4YQTA 4YQNA 3ONPA 5CO4A 4CNGA 5D9FA 4YPWA 1VHKA 4XBOA 4YQLA 4J3CA 4L69A 2I6DA 4YVIA 4YQ5A 3E5YA 3NK7A 1OY5A 4KDZA 2YY8A 2QMMA 4YQDA 3BBDA 4YQRA 3KTYA 2V3KA 4YQ2A 4YQ1A 4MCCA 3OIIA 3KW2A 1UAKA 3O7BA 1Z85A 1J85A 4CNDA 1K3RA 3IEFA 5GMCA 4IG6A 1MXIA 4YQIA 4KGNA 1ZJRA 4YVHA 4YQKA 2Z0YA 1X7PA 3QUVA 2V3JA 4YQ9A 4X3LA 1V2XA 4H3YA 3ILKA 4YQOA 4YQBA 3AIAA 4CNEA 1UAMA 3NK6A 4YQCA 2EGVA 5GM8A 2CX8A 4MCDA 4X3MA 4YQQA 1NS5A 4JWFA 3AXZA 2HA8A 4JWGA 4YQ3A 1NXZA 4FAKA 4FMWA 4YVGA 3N4JA 1IPAA 3BBHA 1UAJA 1V6ZA 4YQPA 3L8UA 1TO0A 4YQ0A 3BBEA 3DCMX 4YQ6A 1GZ0A 4H3ZA 3KNUA 4YPYA 4E8BA 1VHYA 1VH0A 4YVJA 4JWHA 4CNFA 5FAIA 4YQ7A 4PZKA 5GMBA 1UALA 3N4KA 3OINA 3GYQA 4YQAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O6D A;  4YQ8 A;  4YVK A;  4YPX A;  3AI9 X;  3OIJ A;  4YPZ A;  3KY7 A;  4MCB A;  4YQJ A;  4JAL A;  4RG1 A;  4YQ4 A;  1P9P A;  2EGW A;  4YQG A;  4YQS A;  4JAK A;  2O3A A;  2QWV A;  1X7O A;  3IC6 A;  4YQT A;  4YQN A;  3ONP A;  5CO4 A;  4CNG A;  5D9F A;  4YPW A;  1VHK A;  4XBO A;  4YQL A;  4J3C A;  4L69 A;  2I6D A;  4YVI A;  4YQ5 A;  3E5Y A;  3NK7 A;  1OY5 A;  4KDZ A;  2YY8 A;  2QMM A;  4YQD A;  3BBD A;  4YQR A;  3KTY A;  2V3K A;  4YQ2 A;  4YQ1 A;  4MCC A;  3OII A;  3KW2 A;  1UAK A;  3O7B A;  1Z85 A;  1J85 A;  4CND A;  1K3R A;  3IEF A;  5GMC A;  4IG6 A;  1MXI A;  4YQI A;  4KGN A;  1ZJR A;  4YVH A;  4YQK A;  2Z0Y A;  1X7P A;  3QUV A;  2V3J A;  4YQ9 A;  4X3L A;  1V2X A;  4H3Y A;  3ILK A;  4YQO A;  4YQB A;  3AIA A;  4CNE A;  1UAM A;  3NK6 A;  4YQC A;  2EGV A;  5GM8 A;  2CX8 A;  4MCD A;  4X3M A;  4YQQ A;  1NS5 A;  3AXZ A;  2HA8 A;  4YQ3 A;  1NXZ A;  4FAK A;  4YVG A;  3N4J A;  1IPA A;  3BBH A;  1UAJ A;  1V6Z A;  4YQP A;  3L8U A;  1TO0 A;  4YQ0 A;  3BBE A;  3DCM X;  4YQ6 A;  1GZ0 A;  4H3Z A;  3KNU A;  4YPY A;  4E8B A;  1VHY A;  1VH0 A;  4YVJ A;  4CNF A;  5FAI A;  4YQ7 A;  4PZK A;  5GMB A;  1UAL A;  3N4K A;  3OIN A;  3GYQ A;  4YQA A; 
#chains in the Genus database with same CATH topology
 1O6D A;  4YQ8 A;  4YVK A;  4YPX A;  3AI9 X;  3OIJ A;  4YPZ A;  3KY7 A;  4MCB A;  4JWJ A;  4YQJ A;  4JAL A;  1WRS R;  4RG1 A;  4YQ4 A;  1P9P A;  2EGW A;  4YQG A;  4YQS A;  4JAK A;  2O3A A;  2QWV A;  1X7O A;  3IC6 A;  1WRT R;  4YQT A;  4YQN A;  3ONP A;  5CO4 A;  4CNG A;  5D9F A;  4YPW A;  1VHK A;  4XBO A;  4YQL A;  2OZ9 R;  4J3C A;  4L69 A;  2I6D A;  4YVI A;  4YQ5 A;  3E5Y A;  3NK7 A;  1WRP R;  1OY5 A;  4KDZ A;  2YY8 A;  2QMM A;  4YQD A;  3BBD A;  4YQR A;  3KTY A;  2V3K A;  4YQ2 A;  4YQ1 A;  4MCC A;  3OII A;  3KW2 A;  2XDI A;  1RCS A;  1UAK A;  3O7B A;  1Z85 A;  1J85 A;  4CND A;  1K3R A;  1CO0 A;  3IEF A;  5GMC A;  4IG6 A;  1MXI A;  3G1C A;  4YQI A;  4KGN A;  1ZJR A;  4YVH A;  4YQK A;  2Z0Y A;  1X7P A;  3QUV A;  3SSW N;  2V3J A;  3KOR A;  1ZT9 A;  4YQ9 A;  4X3L A;  1V2X A;  4H3Y A;  3SSX N;  3ILK A;  4YQO A;  4YQB A;  1MI7 R;  1TRR A;  3AIA A;  4CNE A;  1UAM A;  3NK6 A;  4YQC A;  3FRW A;  2EGV A;  5GM8 A;  2CX8 A;  4MCD A;  4X3M A;  4YQQ A;  1TRO A;  1NS5 A;  3AXZ A;  4JWF A;  2HA8 A;  1JHG A;  4JWG A;  4YQ3 A;  1NXZ A;  4FAK A;  4FMW A;  4YVG A;  3N4J A;  1IPA A;  3BBH A;  1UAJ A;  3WRP A;  1V6Z A;  4YQP A;  3L8U A;  1TO0 A;  4YQ0 A;  3BBE A;  3DCM X;  4YQ6 A;  1GZ0 A;  4H3Z A;  3KNU A;  4YPY A;  4E8B A;  1VHY A;  1VH0 A;  4YVJ A;  4JWH A;  4CNF A;  5FAI A;  4YQ7 A;  4PZK A;  5GMB A;  1UAL A;  3N4K A;  3OIN A;  3GYQ A;  4YQA A; 
#chains in the Genus database with same CATH homology
 1O6D A;  4YQ8 A;  4YVK A;  4YPX A;  3AI9 X;  3OIJ A;  4YPZ A;  3KY7 A;  4MCB A;  4JWJ A;  4YQJ A;  4JAL A;  4RG1 A;  4YQ4 A;  1P9P A;  2EGW A;  4YQG A;  4YQS A;  4JAK A;  2O3A A;  2QWV A;  1X7O A;  3IC6 A;  4YQT A;  4YQN A;  3ONP A;  5CO4 A;  4CNG A;  5D9F A;  4YPW A;  1VHK A;  4XBO A;  4YQL A;  4J3C A;  4L69 A;  2I6D A;  4YVI A;  4YQ5 A;  3E5Y A;  3NK7 A;  1OY5 A;  4KDZ A;  2YY8 A;  2QMM A;  4YQD A;  3BBD A;  4YQR A;  3KTY A;  2V3K A;  4YQ2 A;  4YQ1 A;  4MCC A;  3OII A;  3KW2 A;  1UAK A;  3O7B A;  1Z85 A;  1J85 A;  4CND A;  1K3R A;  3IEF A;  5GMC A;  4IG6 A;  1MXI A;  4YQI A;  4KGN A;  1ZJR A;  4YVH A;  4YQK A;  2Z0Y A;  1X7P A;  3QUV A;  2V3J A;  4YQ9 A;  4X3L A;  1V2X A;  4H3Y A;  3ILK A;  4YQO A;  4YQB A;  3AIA A;  4CNE A;  1UAM A;  3NK6 A;  4YQC A;  2EGV A;  5GM8 A;  2CX8 A;  4MCD A;  4X3M A;  4YQQ A;  1NS5 A;  4JWF A;  3AXZ A;  2HA8 A;  4JWG A;  4YQ3 A;  1NXZ A;  4FAK A;  4FMW A;  4YVG A;  3N4J A;  1IPA A;  3BBH A;  1UAJ A;  1V6Z A;  4YQP A;  3L8U A;  1TO0 A;  4YQ0 A;  3BBE A;  3DCM X;  4YQ6 A;  1GZ0 A;  4H3Z A;  3KNU A;  4YPY A;  4E8B A;  1VHY A;  1VH0 A;  4YVJ A;  4JWH A;  4CNF A;  5FAI A;  4YQ7 A;  4PZK A;  5GMB A;  1UAL A;  3N4K A;  3OIN A;  3GYQ A;  4YQA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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