4YQCA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
248
structure length
237
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 72
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqcA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqcA01
4YQNA 4XBOA 1O6DA 4YQGA 4YVKA 1IPAA 1UAJA 4YQTA 4CNEA 4YQ3A 4E8BA 4IG6A 1MXIA 3ILKA 3O7BA 3NK6A 2QMMA 4YQAA 4CNDA 4MCDA 4J3CA 4YQJA 3KW2A 4YQ1A 3L8UA 4CNFA 3KTYA 1VHYA 1OY5A 5GMCA 4YQLA 1NXZA 1V2XA 4YPXA 4H3YA 4JAKA 4MCCA 3NK7A 4YPYA 4JALA 1UAKA 1UALA 4L69A 5CO4A 4KDZA 4YQDA 4YVIA 4YQRA 4YQSA 1Z85A 4X3LA 1V6ZA 4YQ5A 2Z0YA 4CNGA 3N4JA 4YPZA 2I6DA 3N4KA 4YVGA 4YQKA 2EGVA 4YQ0A 3IC6A 5GMBA 4H3ZA 4YQ4A 3BBEA 2QWVA 2CX8A 1J85A 4YQCA 4PZKA 4RG1A 3BBHA 4YQ6A 4YVJA 2YY8A 5FAIA 4YQBA 4YQQA 2EGWA 4FAKA 2O3AA 1VHKA 2V3KA 4X3MA 2V3JA 1TO0A 1ZJRA 2HA8A 4YQIA 3OIJA 4KGNA 3ONPA 5GM8A 3BBDA 3AIAA 3OIIA 4YVHA 1UAMA 5D9FA 4YQ2A 1X7PA 4YQ9A 3AXZA 3KNUA 4YQOA 1X7OA 4YQ8A 3DCMX 3E5YA 3IEFA 4YPWA 3GYQA 3OINA 3AI9X 4YQPA 4MCBA 3QUVA 1VH0A 1P9PA 4YQ7A 3KY7A 1GZ0A 1NS5A 1K3RA
chains in the Genus database with same CATH superfamily
4YQNA 4XBOA 1O6DA 4YQGA 4YVKA 1IPAA 1UAJA 4YQTA 4CNEA 4YQ3A 4E8BA 4IG6A 2XDIA 1MXIA 3ILKA 3O7BA 3NK6A 2QMMA 4YQAA 4CNDA 4MCDA 4J3CA 4YQJA 3KW2A 4YQ1A 2OZ9R 3L8UA 4CNFA 1TROA 3KTYA 1VHYA 1OY5A 5GMCA 4YQLA 1NXZA 1V2XA 4YPXA 4JWHA 4H3YA 4JAKA 4MCCA 3NK7A 4YPYA 4JALA 1UAKA 3SSWN 1UALA 4L69A 5CO4A 1WRSR 4FMWA 4KDZA 4YQDA 1WRTR 4YVIA 1JHGA 4YQRA 4YQSA 1Z85A 4X3LA 1V6ZA 4YQ5A 2Z0YA 4CNGA 3N4JA 1TRRA 4YPZA 2I6DA 3N4KA 3SSXN 4YVGA 4YQKA 2EGVA 4YQ0A 3KORA 3IC6A 5GMBA 4H3ZA 4YQ4A 3G1CA 2QWVA 2CX8A 3BBEA 1J85A 4YQCA 4PZKA 4RG1A 1ZT9A 3BBHA 4YQ6A 4YVJA 1WRPR 2YY8A 5FAIA 4JWGA 4YQBA 4YQQA 2EGWA 4FAKA 2O3AA 1VHKA 2V3KA 4X3MA 2V3JA 1TO0A 1ZJRA 2HA8A 4YQIA 3OIJA 4KGNA 3ONPA 5GM8A 3BBDA 3AIAA 3OIIA 4YVHA 1UAMA 3FRWA 5D9FA 4YQ2A 1X7PA 4YQ9A 3AXZA 3KNUA 4YQOA 1X7OA 4YQ8A 3DCMX 3E5YA 1CO0A 3IEFA 4YPWA 3GYQA 3OINA 3AI9X 4YQPA 4MCBA 3WRPA 3QUVA 1RCSA 4JWFA 1VH0A 1P9PA 4YQ7A 3KY7A 1GZ0A 1NS5A 1MI7R 4JWJA 1K3RA
chains in the Genus database with same CATH topology
4YQNA 4XBOA 1O6DA 4YQGA 4YVKA 1IPAA 1UAJA 4YQTA 4CNEA 4YQ3A 4E8BA 4IG6A 1MXIA 3ILKA 3O7BA 3NK6A 2QMMA 4YQAA 4CNDA 4MCDA 4J3CA 4YQJA 3KW2A 4YQ1A 3L8UA 4CNFA 3KTYA 1VHYA 1OY5A 5GMCA 4YQLA 1NXZA 1V2XA 4YPXA 4JWHA 4H3YA 4JAKA 4MCCA 3NK7A 4YPYA 4JALA 1UAKA 1UALA 4L69A 5CO4A 4FMWA 4KDZA 4YQDA 4YVIA 4YQRA 4YQSA 1Z85A 4X3LA 1V6ZA 4YQ5A 2Z0YA 4CNGA 3N4JA 4YPZA 2I6DA 3N4KA 4YVGA 4YQKA 2EGVA 4YQ0A 3IC6A 5GMBA 4H3ZA 4YQ4A 3BBEA 2QWVA 2CX8A 1J85A 4YQCA 4PZKA 4RG1A 3BBHA 4YQ6A 4YVJA 2YY8A 5FAIA 4JWGA 4YQBA 4YQQA 2EGWA 4FAKA 2O3AA 1VHKA 2V3KA 4X3MA 2V3JA 1TO0A 1ZJRA 2HA8A 4YQIA 3OIJA 4KGNA 3ONPA 5GM8A 3BBDA 3AIAA 3OIIA 4YVHA 1UAMA 5D9FA 4YQ2A 1X7PA 4YQ9A 3AXZA 3KNUA 4YQOA 1X7OA 4YQ8A 3DCMX 3E5YA 3IEFA 4YPWA 3GYQA 3OINA 3AI9X 4YQPA 4MCBA 3QUVA 4JWFA 1VH0A 1P9PA 4YQ7A 3KY7A 1GZ0A 1NS5A 4JWJA 1K3RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQN A;  4XBO A;  1O6D A;  4YQG A;  4YVK A;  1IPA A;  1UAJ A;  4YQT A;  4CNE A;  4YQ3 A;  4E8B A;  4IG6 A;  1MXI A;  3ILK A;  3O7B A;  3NK6 A;  2QMM A;  4YQA A;  4CND A;  4MCD A;  4J3C A;  4YQJ A;  3KW2 A;  4YQ1 A;  3L8U A;  4CNF A;  3KTY A;  1VHY A;  1OY5 A;  5GMC A;  4YQL A;  1NXZ A;  1V2X A;  4YPX A;  4H3Y A;  4JAK A;  4MCC A;  3NK7 A;  4YPY A;  4JAL A;  1UAK A;  1UAL A;  4L69 A;  5CO4 A;  4KDZ A;  4YQD A;  4YVI A;  4YQR A;  4YQS A;  1Z85 A;  4X3L A;  1V6Z A;  4YQ5 A;  2Z0Y A;  4CNG A;  3N4J A;  4YPZ A;  2I6D A;  3N4K A;  4YVG A;  4YQK A;  2EGV A;  4YQ0 A;  3IC6 A;  5GMB A;  4H3Z A;  4YQ4 A;  3BBE A;  2QWV A;  2CX8 A;  1J85 A;  4YQC A;  4PZK A;  4RG1 A;  3BBH A;  4YQ6 A;  4YVJ A;  2YY8 A;  5FAI A;  4YQB A;  4YQQ A;  2EGW A;  4FAK A;  2O3A A;  1VHK A;  2V3K A;  4X3M A;  2V3J A;  1TO0 A;  1ZJR A;  2HA8 A;  4YQI A;  3OIJ A;  4KGN A;  3ONP A;  5GM8 A;  3BBD A;  3AIA A;  3OII A;  4YVH A;  1UAM A;  5D9F A;  4YQ2 A;  1X7P A;  4YQ9 A;  3AXZ A;  3KNU A;  4YQO A;  1X7O A;  4YQ8 A;  3DCM X;  3E5Y A;  3IEF A;  4YPW A;  3GYQ A;  3OIN A;  3AI9 X;  4YQP A;  4MCB A;  3QUV A;  1VH0 A;  1P9P A;  4YQ7 A;  3KY7 A;  1GZ0 A;  1NS5 A;  1K3R A; 
#chains in the Genus database with same CATH topology
 4YQN A;  4XBO A;  1O6D A;  4YQG A;  4YVK A;  1IPA A;  1UAJ A;  4YQT A;  4CNE A;  4YQ3 A;  4E8B A;  4IG6 A;  2XDI A;  1MXI A;  3ILK A;  3O7B A;  3NK6 A;  2QMM A;  4YQA A;  4CND A;  4MCD A;  4J3C A;  4YQJ A;  3KW2 A;  4YQ1 A;  2OZ9 R;  3L8U A;  4CNF A;  1TRO A;  3KTY A;  1VHY A;  1OY5 A;  5GMC A;  4YQL A;  1NXZ A;  1V2X A;  4YPX A;  4JWH A;  4H3Y A;  4JAK A;  4MCC A;  3NK7 A;  4YPY A;  4JAL A;  1UAK A;  3SSW N;  1UAL A;  4L69 A;  5CO4 A;  1WRS R;  4FMW A;  4KDZ A;  4YQD A;  1WRT R;  4YVI A;  1JHG A;  4YQR A;  4YQS A;  1Z85 A;  4X3L A;  1V6Z A;  4YQ5 A;  2Z0Y A;  4CNG A;  3N4J A;  1TRR A;  4YPZ A;  2I6D A;  3N4K A;  3SSX N;  4YVG A;  4YQK A;  2EGV A;  4YQ0 A;  3KOR A;  3IC6 A;  5GMB A;  4H3Z A;  4YQ4 A;  3G1C A;  2QWV A;  2CX8 A;  3BBE A;  1J85 A;  4YQC A;  4PZK A;  4RG1 A;  1ZT9 A;  3BBH A;  4YQ6 A;  4YVJ A;  1WRP R;  2YY8 A;  5FAI A;  4JWG A;  4YQB A;  4YQQ A;  2EGW A;  4FAK A;  2O3A A;  1VHK A;  2V3K A;  4X3M A;  2V3J A;  1TO0 A;  1ZJR A;  2HA8 A;  4YQI A;  3OIJ A;  4KGN A;  3ONP A;  5GM8 A;  3BBD A;  3AIA A;  3OII A;  4YVH A;  1UAM A;  3FRW A;  5D9F A;  4YQ2 A;  1X7P A;  4YQ9 A;  3AXZ A;  3KNU A;  4YQO A;  1X7O A;  4YQ8 A;  3DCM X;  3E5Y A;  1CO0 A;  3IEF A;  4YPW A;  3GYQ A;  3OIN A;  3AI9 X;  4YQP A;  4MCB A;  3WRP A;  3QUV A;  1RCS A;  4JWF A;  1VH0 A;  1P9P A;  4YQ7 A;  3KY7 A;  1GZ0 A;  1NS5 A;  1MI7 R;  4JWJ A;  1K3R A; 
#chains in the Genus database with same CATH homology
 4YQN A;  4XBO A;  1O6D A;  4YQG A;  4YVK A;  1IPA A;  1UAJ A;  4YQT A;  4CNE A;  4YQ3 A;  4E8B A;  4IG6 A;  1MXI A;  3ILK A;  3O7B A;  3NK6 A;  2QMM A;  4YQA A;  4CND A;  4MCD A;  4J3C A;  4YQJ A;  3KW2 A;  4YQ1 A;  3L8U A;  4CNF A;  3KTY A;  1VHY A;  1OY5 A;  5GMC A;  4YQL A;  1NXZ A;  1V2X A;  4YPX A;  4JWH A;  4H3Y A;  4JAK A;  4MCC A;  3NK7 A;  4YPY A;  4JAL A;  1UAK A;  1UAL A;  4L69 A;  5CO4 A;  4FMW A;  4KDZ A;  4YQD A;  4YVI A;  4YQR A;  4YQS A;  1Z85 A;  4X3L A;  1V6Z A;  4YQ5 A;  2Z0Y A;  4CNG A;  3N4J A;  4YPZ A;  2I6D A;  3N4K A;  4YVG A;  4YQK A;  2EGV A;  4YQ0 A;  3IC6 A;  5GMB A;  4H3Z A;  4YQ4 A;  3BBE A;  2QWV A;  2CX8 A;  1J85 A;  4YQC A;  4PZK A;  4RG1 A;  3BBH A;  4YQ6 A;  4YVJ A;  2YY8 A;  5FAI A;  4JWG A;  4YQB A;  4YQQ A;  2EGW A;  4FAK A;  2O3A A;  1VHK A;  2V3K A;  4X3M A;  2V3J A;  1TO0 A;  1ZJR A;  2HA8 A;  4YQI A;  3OIJ A;  4KGN A;  3ONP A;  5GM8 A;  3BBD A;  3AIA A;  3OII A;  4YVH A;  1UAM A;  5D9F A;  4YQ2 A;  1X7P A;  4YQ9 A;  3AXZ A;  3KNU A;  4YQO A;  1X7O A;  4YQ8 A;  3DCM X;  3E5Y A;  3IEF A;  4YPW A;  3GYQ A;  3OIN A;  3AI9 X;  4YQP A;  4MCB A;  3QUV A;  4JWF A;  1VH0 A;  1P9P A;  4YQ7 A;  3KY7 A;  1GZ0 A;  1NS5 A;  4JWJ A;  1K3R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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