4YQCA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
248
structure length
237
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 72
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqcA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqcA01
4YQ1A 5D9FA 3BBHA 4JALA 4YQ5A 4YQ4A 3KTYA 3IC6A 4YQ7A 1VH0A 1V2XA 3OIJA 1GZ0A 4YQSA 4YPWA 3KNUA 3O7BA 3KW2A 4YQGA 3NK6A 5GM8A 5GMBA 4MCDA 4KGNA 3AI9X 4PZKA 2Z0YA 4YQDA 1OY5A 1ZJRA 3OINA 4X3MA 3IEFA 4YQTA 1MXIA 4MCCA 3E5YA 3GYQA 1P9PA 4L69A 4JAKA 4H3ZA 3QUVA 3BBEA 4J3CA 4YQBA 4KDZA 2YY8A 4YQJA 1X7OA 4YQAA 3N4KA 4YQKA 3ILKA 1UAKA 1IPAA 4YQ2A 1UALA 4YQLA 5CO4A 4RG1A 2O3AA 4CNEA 4MCBA 4CNDA 1VHYA 4YQRA 2CX8A 1J85A 4YQQA 4YQNA 4E8BA 1VHKA 1NXZA 1O6DA 4CNFA 4YPZA 4H3YA 3BBDA 4XBOA 4IG6A 2QWVA 4FAKA 4YQ6A 3N4JA 4YPYA 1X7PA 3OIIA 4YQPA 2I6DA 2EGVA 4X3LA 4YVGA 4YQCA 4YVHA 3KY7A 4YQ0A 3AIAA 2EGWA 1K3RA 2QMMA 2HA8A 3NK7A 5FAIA 3L8UA 3AXZA 1NS5A 4YQOA 4YQIA 4YVIA 4YPXA 4YQ8A 1V6ZA 4YVKA 4YVJA 1TO0A 2V3KA 1Z85A 5GMCA 1UAMA 1UAJA 4YQ3A 2V3JA 4CNGA 3ONPA 4YQ9A 3DCMX
chains in the Genus database with same CATH superfamily
4YQ1A 5D9FA 3BBHA 4JALA 4YQ5A 4YQ4A 3KTYA 3IC6A 4YQ7A 1VH0A 1V2XA 3OIJA 1GZ0A 4YQSA 4YPWA 3KNUA 3O7BA 3KW2A 1WRTR 4YQGA 3NK6A 5GM8A 2XDIA 5GMBA 4MCDA 4KGNA 3AI9X 1JHGA 4PZKA 2Z0YA 4YQDA 1OY5A 3SSXN 1ZJRA 3OINA 4X3MA 3IEFA 4YQTA 1MXIA 4MCCA 4JWJA 1TRRA 3E5YA 3KORA 3GYQA 3WRPA 1P9PA 4L69A 4JAKA 4H3ZA 3QUVA 3BBEA 4J3CA 4YQBA 4KDZA 2YY8A 4YQJA 1X7OA 4YQAA 3N4KA 4JWGA 4YQKA 3ILKA 4JWHA 1UAKA 1IPAA 4YQ2A 1UALA 4YQLA 5CO4A 1WRPR 3FRWA 4FMWA 4RG1A 2O3AA 4CNEA 1CO0A 4MCBA 4CNDA 1VHYA 1MI7R 4YQRA 2CX8A 1J85A 4YQQA 4YQNA 4E8BA 1VHKA 1NXZA 1O6DA 4CNFA 4YPZA 4H3YA 4JWFA 3BBDA 4XBOA 4IG6A 2QWVA 3SSWN 4FAKA 4YQ6A 1ZT9A 1WRSR 3N4JA 4YPYA 1X7PA 3OIIA 4YQPA 2I6DA 2EGVA 3G1CA 4X3LA 4YVGA 4YQCA 4YVHA 3KY7A 4YQ0A 3AIAA 2EGWA 1K3RA 2QMMA 2HA8A 3NK7A 5FAIA 3L8UA 3AXZA 1TROA 1NS5A 4YQOA 4YQIA 4YVIA 4YPXA 4YQ8A 1V6ZA 4YVKA 4YVJA 1TO0A 2V3KA 1Z85A 5GMCA 1UAMA 1UAJA 4YQ3A 2V3JA 4CNGA 3ONPA 2OZ9R 1RCSA 4YQ9A 3DCMX
chains in the Genus database with same CATH topology
4YQ1A 5D9FA 3BBHA 4JALA 4YQ5A 4YQ4A 3KTYA 3IC6A 4YQ7A 1VH0A 1V2XA 3OIJA 1GZ0A 4YQSA 4YPWA 3KNUA 3O7BA 3KW2A 4YQGA 3NK6A 5GM8A 5GMBA 4MCDA 4KGNA 3AI9X 4PZKA 2Z0YA 4YQDA 1OY5A 1ZJRA 3OINA 4X3MA 3IEFA 4YQTA 1MXIA 4MCCA 4JWJA 3E5YA 3GYQA 1P9PA 4L69A 4JAKA 4H3ZA 3QUVA 3BBEA 4J3CA 4YQBA 4KDZA 2YY8A 4YQJA 1X7OA 4YQAA 3N4KA 4JWGA 4YQKA 3ILKA 4JWHA 1UAKA 1IPAA 4YQ2A 1UALA 4YQLA 5CO4A 4FMWA 4RG1A 2O3AA 4CNEA 4MCBA 4CNDA 1VHYA 4YQRA 2CX8A 1J85A 4YQQA 4YQNA 4E8BA 1VHKA 1NXZA 1O6DA 4CNFA 4YPZA 4H3YA 4JWFA 3BBDA 4XBOA 4IG6A 2QWVA 4FAKA 4YQ6A 3N4JA 4YPYA 1X7PA 3OIIA 4YQPA 2I6DA 2EGVA 4X3LA 4YVGA 4YQCA 4YVHA 3KY7A 4YQ0A 3AIAA 2EGWA 1K3RA 2QMMA 2HA8A 3NK7A 5FAIA 3L8UA 3AXZA 1NS5A 4YQOA 4YQIA 4YVIA 4YPXA 4YQ8A 1V6ZA 4YVKA 4YVJA 1TO0A 2V3KA 1Z85A 5GMCA 1UAMA 1UAJA 4YQ3A 2V3JA 4CNGA 3ONPA 4YQ9A 3DCMX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ1 A;  5D9F A;  3BBH A;  4JAL A;  4YQ5 A;  4YQ4 A;  3KTY A;  3IC6 A;  4YQ7 A;  1VH0 A;  1V2X A;  3OIJ A;  1GZ0 A;  4YQS A;  4YPW A;  3KNU A;  3O7B A;  3KW2 A;  4YQG A;  3NK6 A;  5GM8 A;  5GMB A;  4MCD A;  4KGN A;  3AI9 X;  4PZK A;  2Z0Y A;  4YQD A;  1OY5 A;  1ZJR A;  3OIN A;  4X3M A;  3IEF A;  4YQT A;  1MXI A;  4MCC A;  3E5Y A;  3GYQ A;  1P9P A;  4L69 A;  4JAK A;  4H3Z A;  3QUV A;  3BBE A;  4J3C A;  4YQB A;  4KDZ A;  2YY8 A;  4YQJ A;  1X7O A;  4YQA A;  3N4K A;  4YQK A;  3ILK A;  1UAK A;  1IPA A;  4YQ2 A;  1UAL A;  4YQL A;  5CO4 A;  4RG1 A;  2O3A A;  4CNE A;  4MCB A;  4CND A;  1VHY A;  4YQR A;  2CX8 A;  1J85 A;  4YQQ A;  4YQN A;  4E8B A;  1VHK A;  1NXZ A;  1O6D A;  4CNF A;  4YPZ A;  4H3Y A;  3BBD A;  4XBO A;  4IG6 A;  2QWV A;  4FAK A;  4YQ6 A;  3N4J A;  4YPY A;  1X7P A;  3OII A;  4YQP A;  2I6D A;  2EGV A;  4X3L A;  4YVG A;  4YQC A;  4YVH A;  3KY7 A;  4YQ0 A;  3AIA A;  2EGW A;  1K3R A;  2QMM A;  2HA8 A;  3NK7 A;  5FAI A;  3L8U A;  3AXZ A;  1NS5 A;  4YQO A;  4YQI A;  4YVI A;  4YPX A;  4YQ8 A;  1V6Z A;  4YVK A;  4YVJ A;  1TO0 A;  2V3K A;  1Z85 A;  5GMC A;  1UAM A;  1UAJ A;  4YQ3 A;  2V3J A;  4CNG A;  3ONP A;  4YQ9 A;  3DCM X; 
#chains in the Genus database with same CATH topology
 4YQ1 A;  5D9F A;  3BBH A;  4JAL A;  4YQ5 A;  4YQ4 A;  3KTY A;  3IC6 A;  4YQ7 A;  1VH0 A;  1V2X A;  3OIJ A;  1GZ0 A;  4YQS A;  4YPW A;  3KNU A;  3O7B A;  3KW2 A;  1WRT R;  4YQG A;  3NK6 A;  5GM8 A;  2XDI A;  5GMB A;  4MCD A;  4KGN A;  3AI9 X;  1JHG A;  4PZK A;  2Z0Y A;  4YQD A;  1OY5 A;  3SSX N;  1ZJR A;  3OIN A;  4X3M A;  3IEF A;  4YQT A;  1MXI A;  4MCC A;  4JWJ A;  1TRR A;  3E5Y A;  3KOR A;  3GYQ A;  3WRP A;  1P9P A;  4L69 A;  4JAK A;  4H3Z A;  3QUV A;  3BBE A;  4J3C A;  4YQB A;  4KDZ A;  2YY8 A;  4YQJ A;  1X7O A;  4YQA A;  3N4K A;  4JWG A;  4YQK A;  3ILK A;  4JWH A;  1UAK A;  1IPA A;  4YQ2 A;  1UAL A;  4YQL A;  5CO4 A;  1WRP R;  3FRW A;  4FMW A;  4RG1 A;  2O3A A;  4CNE A;  1CO0 A;  4MCB A;  4CND A;  1VHY A;  1MI7 R;  4YQR A;  2CX8 A;  1J85 A;  4YQQ A;  4YQN A;  4E8B A;  1VHK A;  1NXZ A;  1O6D A;  4CNF A;  4YPZ A;  4H3Y A;  4JWF A;  3BBD A;  4XBO A;  4IG6 A;  2QWV A;  3SSW N;  4FAK A;  4YQ6 A;  1ZT9 A;  1WRS R;  3N4J A;  4YPY A;  1X7P A;  3OII A;  4YQP A;  2I6D A;  2EGV A;  3G1C A;  4X3L A;  4YVG A;  4YQC A;  4YVH A;  3KY7 A;  4YQ0 A;  3AIA A;  2EGW A;  1K3R A;  2QMM A;  2HA8 A;  3NK7 A;  5FAI A;  3L8U A;  3AXZ A;  1TRO A;  1NS5 A;  4YQO A;  4YQI A;  4YVI A;  4YPX A;  4YQ8 A;  1V6Z A;  4YVK A;  4YVJ A;  1TO0 A;  2V3K A;  1Z85 A;  5GMC A;  1UAM A;  1UAJ A;  4YQ3 A;  2V3J A;  4CNG A;  3ONP A;  2OZ9 R;  1RCS A;  4YQ9 A;  3DCM X; 
#chains in the Genus database with same CATH homology
 4YQ1 A;  5D9F A;  3BBH A;  4JAL A;  4YQ5 A;  4YQ4 A;  3KTY A;  3IC6 A;  4YQ7 A;  1VH0 A;  1V2X A;  3OIJ A;  1GZ0 A;  4YQS A;  4YPW A;  3KNU A;  3O7B A;  3KW2 A;  4YQG A;  3NK6 A;  5GM8 A;  5GMB A;  4MCD A;  4KGN A;  3AI9 X;  4PZK A;  2Z0Y A;  4YQD A;  1OY5 A;  1ZJR A;  3OIN A;  4X3M A;  3IEF A;  4YQT A;  1MXI A;  4MCC A;  4JWJ A;  3E5Y A;  3GYQ A;  1P9P A;  4L69 A;  4JAK A;  4H3Z A;  3QUV A;  3BBE A;  4J3C A;  4YQB A;  4KDZ A;  2YY8 A;  4YQJ A;  1X7O A;  4YQA A;  3N4K A;  4JWG A;  4YQK A;  3ILK A;  4JWH A;  1UAK A;  1IPA A;  4YQ2 A;  1UAL A;  4YQL A;  5CO4 A;  4FMW A;  4RG1 A;  2O3A A;  4CNE A;  4MCB A;  4CND A;  1VHY A;  4YQR A;  2CX8 A;  1J85 A;  4YQQ A;  4YQN A;  4E8B A;  1VHK A;  1NXZ A;  1O6D A;  4CNF A;  4YPZ A;  4H3Y A;  4JWF A;  3BBD A;  4XBO A;  4IG6 A;  2QWV A;  4FAK A;  4YQ6 A;  3N4J A;  4YPY A;  1X7P A;  3OII A;  4YQP A;  2I6D A;  2EGV A;  4X3L A;  4YVG A;  4YQC A;  4YVH A;  3KY7 A;  4YQ0 A;  3AIA A;  2EGW A;  1K3R A;  2QMM A;  2HA8 A;  3NK7 A;  5FAI A;  3L8U A;  3AXZ A;  1NS5 A;  4YQO A;  4YQI A;  4YVI A;  4YPX A;  4YQ8 A;  1V6Z A;  4YVK A;  4YVJ A;  1TO0 A;  2V3K A;  1Z85 A;  5GMC A;  1UAM A;  1UAJ A;  4YQ3 A;  2V3J A;  4CNG A;  3ONP A;  4YQ9 A;  3DCM X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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