4YQGA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
248
structure length
237
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqgA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqgA01
4YQ3A 2YY8A 4YPZA 4YQ7A 1OY5A 4YQ9A 1ZJRA 1VH0A 2QWVA 3QUVA 4YQIA 1TO0A 4CNFA 2EGVA 4YQNA 4XBOA 3AXZA 4YQJA 3IC6A 3L8UA 4H3YA 4YQ0A 3O7BA 4MCBA 4YQ4A 4YQCA 4YQ5A 3OINA 4JALA 4YQPA 4YQ6A 4YQOA 3BBHA 4YQAA 5FAIA 3KW2A 4YQ2A 3OIIA 4YQDA 1UAJA 5GMCA 1IPAA 1NS5A 1J85A 4YQ8A 4YVKA 2I6DA 5GMBA 4IG6A 2O3AA 1UAMA 4YQ1A 5D9FA 1VHYA 3AI9X 3N4JA 1NXZA 4L69A 2CX8A 4X3LA 4YVGA 1UAKA 4YQTA 3KY7A 3OIJA 4YPXA 3BBEA 1X7PA 4YPYA 3ONPA 2V3JA 5GM8A 1VHKA 4CNEA 4YQGA 3NK6A 3BBDA 2Z0YA 4KDZA 4YQKA 4YQSA 4YQLA 1K3RA 5CO4A 3DCMX 4X3MA 1V2XA 1MXIA 3IEFA 2V3KA 4CNDA 4MCDA 3AIAA 4YVJA 4H3ZA 1O6DA 2QMMA 3NK7A 4JAKA 1P9PA 4CNGA 4YQQA 4MCCA 4YPWA 2EGWA 4FAKA 3GYQA 2HA8A 4KGNA 1UALA 4YVIA 1X7OA 4PZKA 1Z85A 3N4KA 4J3CA 3KTYA 3E5YA 3KNUA 3ILKA 4YVHA 1GZ0A 4RG1A 4YQBA 1V6ZA 4E8BA 4YQRA
chains in the Genus database with same CATH superfamily
4YQ3A 2YY8A 3SSWN 4YPZA 4YQ7A 1OY5A 4YQ9A 1ZJRA 1VH0A 2QWVA 3QUVA 4YQIA 1TO0A 4CNFA 2EGVA 4YQNA 1CO0A 4XBOA 1JHGA 3AXZA 4YQJA 3IC6A 3L8UA 4H3YA 4YQ0A 3O7BA 4FMWA 4MCBA 4YQ4A 4YQCA 3SSXN 4YQ5A 3OINA 4JALA 1MI7R 4YQPA 4YQ6A 1WRPR 4YQOA 3BBHA 4YQAA 5FAIA 3KW2A 3KORA 4YQ2A 3OIIA 4JWFA 4YQDA 1UAJA 3G1CA 5GMCA 1IPAA 2OZ9R 1NS5A 1J85A 4JWJA 4YQ8A 4YVKA 1TROA 2I6DA 5GMBA 4IG6A 2O3AA 1UAMA 4YQ1A 5D9FA 3FRWA 4JWGA 1VHYA 3AI9X 3N4JA 1NXZA 4L69A 2CX8A 4X3LA 4YVGA 1UAKA 4YQTA 3KY7A 4JWHA 4YPXA 3BBEA 3OIJA 1X7PA 4YPYA 1RCSA 3ONPA 2V3JA 5GM8A 1VHKA 4CNEA 4YQGA 3NK6A 3BBDA 2Z0YA 4KDZA 4YQKA 4YQSA 4YQLA 1K3RA 5CO4A 1ZT9A 3DCMX 4X3MA 1V2XA 1MXIA 3IEFA 2V3KA 4CNDA 4MCDA 3AIAA 1WRSR 4YVJA 4H3ZA 1WRTR 1O6DA 2QMMA 3NK7A 4JAKA 1P9PA 4CNGA 4YQQA 4MCCA 4YPWA 2EGWA 3WRPA 4FAKA 3GYQA 2HA8A 4KGNA 1UALA 4YVIA 1X7OA 1TRRA 4PZKA 1Z85A 3N4KA 4J3CA 3KTYA 3E5YA 3KNUA 3ILKA 4YVHA 1GZ0A 4RG1A 2XDIA 4YQBA 1V6ZA 4E8BA 4YQRA
chains in the Genus database with same CATH topology
4YQ3A 2YY8A 4YPZA 4YQ7A 1OY5A 4YQ9A 1ZJRA 1VH0A 2QWVA 3QUVA 4YQIA 1TO0A 4CNFA 2EGVA 4YQNA 4XBOA 3AXZA 4YQJA 3IC6A 3L8UA 4H3YA 4YQ0A 3O7BA 4FMWA 4MCBA 4YQ4A 4YQCA 4YQ5A 3OINA 4JALA 4YQPA 4YQ6A 4YQOA 3BBHA 4YQAA 5FAIA 3KW2A 4YQ2A 3OIIA 4JWFA 4YQDA 1UAJA 5GMCA 1IPAA 1NS5A 1J85A 4JWJA 4YQ8A 4YVKA 2I6DA 5GMBA 4IG6A 2O3AA 1UAMA 4YQ1A 5D9FA 4JWGA 1VHYA 3AI9X 3N4JA 1NXZA 4L69A 2CX8A 4X3LA 4YVGA 1UAKA 4YQTA 3KY7A 4JWHA 4YPXA 3BBEA 3OIJA 1X7PA 4YPYA 3ONPA 2V3JA 5GM8A 1VHKA 4CNEA 4YQGA 3NK6A 3BBDA 2Z0YA 4KDZA 4YQKA 4YQSA 4YQLA 1K3RA 5CO4A 3DCMX 4X3MA 1V2XA 1MXIA 3IEFA 2V3KA 4CNDA 4MCDA 3AIAA 4YVJA 4H3ZA 1O6DA 2QMMA 3NK7A 4JAKA 1P9PA 4CNGA 4YQQA 4MCCA 4YPWA 2EGWA 4FAKA 3GYQA 2HA8A 4KGNA 1UALA 4YVIA 1X7OA 4PZKA 1Z85A 3N4KA 4J3CA 3KTYA 3E5YA 3KNUA 3ILKA 4YVHA 1GZ0A 4RG1A 4YQBA 1V6ZA 4E8BA 4YQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ3 A;  2YY8 A;  4YPZ A;  4YQ7 A;  1OY5 A;  4YQ9 A;  1ZJR A;  1VH0 A;  2QWV A;  3QUV A;  4YQI A;  1TO0 A;  4CNF A;  2EGV A;  4YQN A;  4XBO A;  3AXZ A;  4YQJ A;  3IC6 A;  3L8U A;  4H3Y A;  4YQ0 A;  3O7B A;  4MCB A;  4YQ4 A;  4YQC A;  4YQ5 A;  3OIN A;  4JAL A;  4YQP A;  4YQ6 A;  4YQO A;  3BBH A;  4YQA A;  5FAI A;  3KW2 A;  4YQ2 A;  3OII A;  4YQD A;  1UAJ A;  5GMC A;  1IPA A;  1NS5 A;  1J85 A;  4YQ8 A;  4YVK A;  2I6D A;  5GMB A;  4IG6 A;  2O3A A;  1UAM A;  4YQ1 A;  5D9F A;  1VHY A;  3AI9 X;  3N4J A;  1NXZ A;  4L69 A;  2CX8 A;  4X3L A;  4YVG A;  1UAK A;  4YQT A;  3KY7 A;  3OIJ A;  4YPX A;  3BBE A;  1X7P A;  4YPY A;  3ONP A;  2V3J A;  5GM8 A;  1VHK A;  4CNE A;  4YQG A;  3NK6 A;  3BBD A;  2Z0Y A;  4KDZ A;  4YQK A;  4YQS A;  4YQL A;  1K3R A;  5CO4 A;  3DCM X;  4X3M A;  1V2X A;  1MXI A;  3IEF A;  2V3K A;  4CND A;  4MCD A;  3AIA A;  4YVJ A;  4H3Z A;  1O6D A;  2QMM A;  3NK7 A;  4JAK A;  1P9P A;  4CNG A;  4YQQ A;  4MCC A;  4YPW A;  2EGW A;  4FAK A;  3GYQ A;  2HA8 A;  4KGN A;  1UAL A;  4YVI A;  1X7O A;  4PZK A;  1Z85 A;  3N4K A;  4J3C A;  3KTY A;  3E5Y A;  3KNU A;  3ILK A;  4YVH A;  1GZ0 A;  4RG1 A;  4YQB A;  1V6Z A;  4E8B A;  4YQR A; 
#chains in the Genus database with same CATH topology
 4YQ3 A;  2YY8 A;  3SSW N;  4YPZ A;  4YQ7 A;  1OY5 A;  4YQ9 A;  1ZJR A;  1VH0 A;  2QWV A;  3QUV A;  4YQI A;  1TO0 A;  4CNF A;  2EGV A;  4YQN A;  1CO0 A;  4XBO A;  1JHG A;  3AXZ A;  4YQJ A;  3IC6 A;  3L8U A;  4H3Y A;  4YQ0 A;  3O7B A;  4FMW A;  4MCB A;  4YQ4 A;  4YQC A;  3SSX N;  4YQ5 A;  3OIN A;  4JAL A;  1MI7 R;  4YQP A;  4YQ6 A;  1WRP R;  4YQO A;  3BBH A;  4YQA A;  5FAI A;  3KW2 A;  3KOR A;  4YQ2 A;  3OII A;  4JWF A;  4YQD A;  1UAJ A;  3G1C A;  5GMC A;  1IPA A;  2OZ9 R;  1NS5 A;  1J85 A;  4JWJ A;  4YQ8 A;  4YVK A;  1TRO A;  2I6D A;  5GMB A;  4IG6 A;  2O3A A;  1UAM A;  4YQ1 A;  5D9F A;  3FRW A;  4JWG A;  1VHY A;  3AI9 X;  3N4J A;  1NXZ A;  4L69 A;  2CX8 A;  4X3L A;  4YVG A;  1UAK A;  4YQT A;  3KY7 A;  4JWH A;  4YPX A;  3BBE A;  3OIJ A;  1X7P A;  4YPY A;  1RCS A;  3ONP A;  2V3J A;  5GM8 A;  1VHK A;  4CNE A;  4YQG A;  3NK6 A;  3BBD A;  2Z0Y A;  4KDZ A;  4YQK A;  4YQS A;  4YQL A;  1K3R A;  5CO4 A;  1ZT9 A;  3DCM X;  4X3M A;  1V2X A;  1MXI A;  3IEF A;  2V3K A;  4CND A;  4MCD A;  3AIA A;  1WRS R;  4YVJ A;  4H3Z A;  1WRT R;  1O6D A;  2QMM A;  3NK7 A;  4JAK A;  1P9P A;  4CNG A;  4YQQ A;  4MCC A;  4YPW A;  2EGW A;  3WRP A;  4FAK A;  3GYQ A;  2HA8 A;  4KGN A;  1UAL A;  4YVI A;  1X7O A;  1TRR A;  4PZK A;  1Z85 A;  3N4K A;  4J3C A;  3KTY A;  3E5Y A;  3KNU A;  3ILK A;  4YVH A;  1GZ0 A;  4RG1 A;  2XDI A;  4YQB A;  1V6Z A;  4E8B A;  4YQR A; 
#chains in the Genus database with same CATH homology
 4YQ3 A;  2YY8 A;  4YPZ A;  4YQ7 A;  1OY5 A;  4YQ9 A;  1ZJR A;  1VH0 A;  2QWV A;  3QUV A;  4YQI A;  1TO0 A;  4CNF A;  2EGV A;  4YQN A;  4XBO A;  3AXZ A;  4YQJ A;  3IC6 A;  3L8U A;  4H3Y A;  4YQ0 A;  3O7B A;  4FMW A;  4MCB A;  4YQ4 A;  4YQC A;  4YQ5 A;  3OIN A;  4JAL A;  4YQP A;  4YQ6 A;  4YQO A;  3BBH A;  4YQA A;  5FAI A;  3KW2 A;  4YQ2 A;  3OII A;  4JWF A;  4YQD A;  1UAJ A;  5GMC A;  1IPA A;  1NS5 A;  1J85 A;  4JWJ A;  4YQ8 A;  4YVK A;  2I6D A;  5GMB A;  4IG6 A;  2O3A A;  1UAM A;  4YQ1 A;  5D9F A;  4JWG A;  1VHY A;  3AI9 X;  3N4J A;  1NXZ A;  4L69 A;  2CX8 A;  4X3L A;  4YVG A;  1UAK A;  4YQT A;  3KY7 A;  4JWH A;  4YPX A;  3BBE A;  3OIJ A;  1X7P A;  4YPY A;  3ONP A;  2V3J A;  5GM8 A;  1VHK A;  4CNE A;  4YQG A;  3NK6 A;  3BBD A;  2Z0Y A;  4KDZ A;  4YQK A;  4YQS A;  4YQL A;  1K3R A;  5CO4 A;  3DCM X;  4X3M A;  1V2X A;  1MXI A;  3IEF A;  2V3K A;  4CND A;  4MCD A;  3AIA A;  4YVJ A;  4H3Z A;  1O6D A;  2QMM A;  3NK7 A;  4JAK A;  1P9P A;  4CNG A;  4YQQ A;  4MCC A;  4YPW A;  2EGW A;  4FAK A;  3GYQ A;  2HA8 A;  4KGN A;  1UAL A;  4YVI A;  1X7O A;  4PZK A;  1Z85 A;  3N4K A;  4J3C A;  3KTY A;  3E5Y A;  3KNU A;  3ILK A;  4YVH A;  1GZ0 A;  4RG1 A;  4YQB A;  1V6Z A;  4E8B A;  4YQR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...