4YQIA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqiA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqiA01
3AIAA 2I6DA 4H3ZA 3IC6A 4YQ8A 3QUVA 2EGWA 3N4JA 4YPZA 5CO4A 4YQ6A 1MXIA 3BBHA 1Z85A 2QMMA 1ZJRA 4YQNA 4YQDA 3GYQA 1V6ZA 2V3KA 5FAIA 4YQPA 4MCCA 3BBEA 4YQ5A 4YVKA 4IG6A 4YQIA 1GZ0A 4JAKA 4CNEA 3NK7A 4PZKA 4RG1A 4YQBA 4YQLA 2HA8A 4YQKA 3IEFA 4YQ7A 4YPWA 3KNUA 4YVGA 4YQ2A 4YPXA 4YQQA 1OY5A 1UAKA 2EGVA 4YQ4A 4YPYA 4FAKA 4X3MA 3AXZA 1UALA 3ILKA 5GM8A 1TO0A 1K3RA 5GMBA 4YVHA 3BBDA 3KTYA 2O3AA 1NS5A 1UAMA 3DCMX 1VHKA 3L8UA 1O6DA 3OIIA 4YQSA 3E5YA 3OINA 4YVJA 1UAJA 2YY8A 4L69A 4YQAA 1VH0A 1NXZA 4X3LA 4YQTA 1X7OA 3KY7A 4J3CA 1P9PA 3OIJA 4CNDA 4YQCA 4MCDA 4YQ0A 4YQJA 3O7BA 2Z0YA 1J85A 4YQ9A 4YVIA 3N4KA 4YQOA 4YQ1A 4YQRA 4JALA 4E8BA 4YQ3A 2V3JA 2CX8A 1V2XA 4XBOA 4KGNA 4H3YA 4KDZA 5D9FA 3ONPA 4CNGA 4YQGA 1X7PA 2QWVA 4MCBA 4CNFA 3NK6A 3AI9X 1VHYA 5GMCA 3KW2A 1IPAA
chains in the Genus database with same CATH superfamily
3FRWA 3AIAA 2I6DA 4H3ZA 3IC6A 3KW2A 4YQ8A 3QUVA 3KORA 2EGWA 3N4JA 4YPZA 5CO4A 4YQ6A 1MXIA 3BBHA 1Z85A 4JWGA 2QMMA 2OZ9R 3SSXN 1ZJRA 4YQNA 4YQDA 3GYQA 1CO0A 1V6ZA 2V3KA 5FAIA 4YQPA 4MCCA 3BBEA 4YQ5A 4YVKA 4IG6A 4YQIA 1GZ0A 4JAKA 4CNEA 3NK7A 4PZKA 4RG1A 4YQBA 4YQLA 2HA8A 4YQKA 3IEFA 4YQ7A 4YPWA 3KNUA 1WRSR 4YVGA 4FMWA 4YQ2A 4YPXA 4YQQA 1OY5A 1UAKA 2EGVA 4YQ4A 4YPYA 4FAKA 4X3MA 3AXZA 1UALA 3ILKA 5GM8A 1TO0A 1K3RA 5GMBA 4JWHA 4YVHA 3BBDA 3KTYA 2XDIA 2O3AA 1NS5A 1UAMA 3DCMX 1VHKA 3L8UA 3WRPA 1O6DA 3OIIA 4YQSA 3E5YA 3OINA 4YVJA 1UAJA 2YY8A 4L69A 4YQAA 1VH0A 1WRTR 1RCSA 1NXZA 4X3LA 4YQTA 1X7OA 3KY7A 4J3CA 1P9PA 3OIJA 4CNDA 4YQCA 4MCDA 4JWFA 4YQ0A 4YQJA 3O7BA 2Z0YA 1J85A 1TROA 4YQ9A 4YVIA 3N4KA 4YQOA 1TRRA 4YQ1A 4YQRA 4JALA 4E8BA 4YQ3A 2V3JA 2CX8A 1V2XA 4XBOA 4KGNA 4H3YA 4KDZA 5D9FA 3ONPA 4CNGA 4YQGA 1X7PA 2QWVA 4MCBA 4JWJA 4CNFA 3NK6A 1JHGA 3AI9X 1VHYA 5GMCA 3G1CA 3SSWN 1ZT9A 1WRPR 1IPAA 1MI7R
chains in the Genus database with same CATH topology
3AIAA 2I6DA 4H3ZA 3IC6A 4YQ8A 3QUVA 2EGWA 3N4JA 4YPZA 5CO4A 4YQ6A 1MXIA 3BBHA 1Z85A 4JWGA 2QMMA 1ZJRA 4YQNA 4YQDA 3GYQA 1V6ZA 2V3KA 5FAIA 4YQPA 4MCCA 3BBEA 4YQ5A 4YVKA 4IG6A 4YQIA 1GZ0A 4JAKA 4CNEA 3NK7A 4PZKA 4RG1A 4YQBA 4YQLA 2HA8A 4YQKA 3IEFA 4YQ7A 4YPWA 3KNUA 4YVGA 4FMWA 4YQ2A 4YPXA 4YQQA 1OY5A 1UAKA 2EGVA 4YQ4A 4YPYA 4FAKA 4X3MA 3AXZA 1UALA 3ILKA 5GM8A 1TO0A 1K3RA 5GMBA 4JWHA 4YVHA 3BBDA 3KTYA 2O3AA 1NS5A 1UAMA 3DCMX 1VHKA 3L8UA 1O6DA 3OIIA 4YQSA 3E5YA 3OINA 4YVJA 1UAJA 2YY8A 4L69A 4YQAA 1VH0A 1NXZA 4X3LA 4YQTA 1X7OA 3KY7A 4J3CA 1P9PA 3OIJA 4CNDA 4YQCA 4MCDA 4JWFA 4YQ0A 4YQJA 3O7BA 2Z0YA 1J85A 4YQ9A 4YVIA 3N4KA 4YQOA 4YQ1A 4YQRA 4JALA 4E8BA 4YQ3A 2V3JA 2CX8A 1V2XA 4XBOA 4KGNA 4H3YA 4KDZA 5D9FA 3ONPA 4CNGA 4YQGA 1X7PA 2QWVA 4MCBA 4JWJA 4CNFA 3NK6A 3AI9X 1VHYA 5GMCA 3KW2A 1IPAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AIA A;  2I6D A;  4H3Z A;  3IC6 A;  4YQ8 A;  3QUV A;  2EGW A;  3N4J A;  4YPZ A;  5CO4 A;  4YQ6 A;  1MXI A;  3BBH A;  1Z85 A;  2QMM A;  1ZJR A;  4YQN A;  4YQD A;  3GYQ A;  1V6Z A;  2V3K A;  5FAI A;  4YQP A;  4MCC A;  3BBE A;  4YQ5 A;  4YVK A;  4IG6 A;  4YQI A;  1GZ0 A;  4JAK A;  4CNE A;  3NK7 A;  4PZK A;  4RG1 A;  4YQB A;  4YQL A;  2HA8 A;  4YQK A;  3IEF A;  4YQ7 A;  4YPW A;  3KNU A;  4YVG A;  4YQ2 A;  4YPX A;  4YQQ A;  1OY5 A;  1UAK A;  2EGV A;  4YQ4 A;  4YPY A;  4FAK A;  4X3M A;  3AXZ A;  1UAL A;  3ILK A;  5GM8 A;  1TO0 A;  1K3R A;  5GMB A;  4YVH A;  3BBD A;  3KTY A;  2O3A A;  1NS5 A;  1UAM A;  3DCM X;  1VHK A;  3L8U A;  1O6D A;  3OII A;  4YQS A;  3E5Y A;  3OIN A;  4YVJ A;  1UAJ A;  2YY8 A;  4L69 A;  4YQA A;  1VH0 A;  1NXZ A;  4X3L A;  4YQT A;  1X7O A;  3KY7 A;  4J3C A;  1P9P A;  3OIJ A;  4CND A;  4YQC A;  4MCD A;  4YQ0 A;  4YQJ A;  3O7B A;  2Z0Y A;  1J85 A;  4YQ9 A;  4YVI A;  3N4K A;  4YQO A;  4YQ1 A;  4YQR A;  4JAL A;  4E8B A;  4YQ3 A;  2V3J A;  2CX8 A;  1V2X A;  4XBO A;  4KGN A;  4H3Y A;  4KDZ A;  5D9F A;  3ONP A;  4CNG A;  4YQG A;  1X7P A;  2QWV A;  4MCB A;  4CNF A;  3NK6 A;  3AI9 X;  1VHY A;  5GMC A;  3KW2 A;  1IPA A; 
#chains in the Genus database with same CATH topology
 3FRW A;  3AIA A;  2I6D A;  4H3Z A;  3IC6 A;  3KW2 A;  4YQ8 A;  3QUV A;  3KOR A;  2EGW A;  3N4J A;  4YPZ A;  5CO4 A;  4YQ6 A;  1MXI A;  3BBH A;  1Z85 A;  4JWG A;  2QMM A;  2OZ9 R;  3SSX N;  1ZJR A;  4YQN A;  4YQD A;  3GYQ A;  1CO0 A;  1V6Z A;  2V3K A;  5FAI A;  4YQP A;  4MCC A;  3BBE A;  4YQ5 A;  4YVK A;  4IG6 A;  4YQI A;  1GZ0 A;  4JAK A;  4CNE A;  3NK7 A;  4PZK A;  4RG1 A;  4YQB A;  4YQL A;  2HA8 A;  4YQK A;  3IEF A;  4YQ7 A;  4YPW A;  3KNU A;  1WRS R;  4YVG A;  4FMW A;  4YQ2 A;  4YPX A;  4YQQ A;  1OY5 A;  1UAK A;  2EGV A;  4YQ4 A;  4YPY A;  4FAK A;  4X3M A;  3AXZ A;  1UAL A;  3ILK A;  5GM8 A;  1TO0 A;  1K3R A;  5GMB A;  4JWH A;  4YVH A;  3BBD A;  3KTY A;  2XDI A;  2O3A A;  1NS5 A;  1UAM A;  3DCM X;  1VHK A;  3L8U A;  3WRP A;  1O6D A;  3OII A;  4YQS A;  3E5Y A;  3OIN A;  4YVJ A;  1UAJ A;  2YY8 A;  4L69 A;  4YQA A;  1VH0 A;  1WRT R;  1RCS A;  1NXZ A;  4X3L A;  4YQT A;  1X7O A;  3KY7 A;  4J3C A;  1P9P A;  3OIJ A;  4CND A;  4YQC A;  4MCD A;  4JWF A;  4YQ0 A;  4YQJ A;  3O7B A;  2Z0Y A;  1J85 A;  1TRO A;  4YQ9 A;  4YVI A;  3N4K A;  4YQO A;  1TRR A;  4YQ1 A;  4YQR A;  4JAL A;  4E8B A;  4YQ3 A;  2V3J A;  2CX8 A;  1V2X A;  4XBO A;  4KGN A;  4H3Y A;  4KDZ A;  5D9F A;  3ONP A;  4CNG A;  4YQG A;  1X7P A;  2QWV A;  4MCB A;  4JWJ A;  4CNF A;  3NK6 A;  1JHG A;  3AI9 X;  1VHY A;  5GMC A;  3G1C A;  3SSW N;  1ZT9 A;  1WRP R;  1IPA A;  1MI7 R; 
#chains in the Genus database with same CATH homology
 3AIA A;  2I6D A;  4H3Z A;  3IC6 A;  4YQ8 A;  3QUV A;  2EGW A;  3N4J A;  4YPZ A;  5CO4 A;  4YQ6 A;  1MXI A;  3BBH A;  1Z85 A;  4JWG A;  2QMM A;  1ZJR A;  4YQN A;  4YQD A;  3GYQ A;  1V6Z A;  2V3K A;  5FAI A;  4YQP A;  4MCC A;  3BBE A;  4YQ5 A;  4YVK A;  4IG6 A;  4YQI A;  1GZ0 A;  4JAK A;  4CNE A;  3NK7 A;  4PZK A;  4RG1 A;  4YQB A;  4YQL A;  2HA8 A;  4YQK A;  3IEF A;  4YQ7 A;  4YPW A;  3KNU A;  4YVG A;  4FMW A;  4YQ2 A;  4YPX A;  4YQQ A;  1OY5 A;  1UAK A;  2EGV A;  4YQ4 A;  4YPY A;  4FAK A;  4X3M A;  3AXZ A;  1UAL A;  3ILK A;  5GM8 A;  1TO0 A;  1K3R A;  5GMB A;  4JWH A;  4YVH A;  3BBD A;  3KTY A;  2O3A A;  1NS5 A;  1UAM A;  3DCM X;  1VHK A;  3L8U A;  1O6D A;  3OII A;  4YQS A;  3E5Y A;  3OIN A;  4YVJ A;  1UAJ A;  2YY8 A;  4L69 A;  4YQA A;  1VH0 A;  1NXZ A;  4X3L A;  4YQT A;  1X7O A;  3KY7 A;  4J3C A;  1P9P A;  3OIJ A;  4CND A;  4YQC A;  4MCD A;  4JWF A;  4YQ0 A;  4YQJ A;  3O7B A;  2Z0Y A;  1J85 A;  4YQ9 A;  4YVI A;  3N4K A;  4YQO A;  4YQ1 A;  4YQR A;  4JAL A;  4E8B A;  4YQ3 A;  2V3J A;  2CX8 A;  1V2X A;  4XBO A;  4KGN A;  4H3Y A;  4KDZ A;  5D9F A;  3ONP A;  4CNG A;  4YQG A;  1X7P A;  2QWV A;  4MCB A;  4JWJ A;  4CNF A;  3NK6 A;  3AI9 X;  1VHY A;  5GMC A;  3KW2 A;  1IPA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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