4YQKA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
248
structure length
237
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 73
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqkA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqkA01
1K3RA 4YQQA 4YQOA 4YQPA 4YQTA 2CX8A 3N4JA 3OIJA 4YQ1A 2O3AA 5GM8A 3BBEA 2QMMA 1ZJRA 3AI9X 4H3YA 1VHYA 2EGVA 4XBOA 4YQRA 4YPYA 2V3KA 3IEFA 3KTYA 1GZ0A 4J3CA 2I6DA 3N4KA 4YVIA 3L8UA 4YQSA 4YQKA 4YQGA 3IC6A 5GMBA 1NXZA 2Z0YA 3KNUA 3ILKA 4H3ZA 4YQAA 1UALA 1P9PA 4L69A 1UAKA 3OINA 4CNGA 1TO0A 1Z85A 1V2XA 2YY8A 4YQ9A 1X7PA 1UAJA 4CNDA 4YPZA 1J85A 3KW2A 4YQCA 3ONPA 4RG1A 4IG6A 4YQ5A 4YVJA 4YPXA 4YQBA 1IPAA 4YQ4A 4KDZA 4YQLA 4YPWA 4YQ7A 5FAIA 2EGWA 3E5YA 3KY7A 2HA8A 3NK6A 4CNEA 3NK7A 1UAMA 3GYQA 4YQ2A 4JALA 4YQDA 1O6DA 5D9FA 4YVGA 4MCDA 4YQ0A 4X3LA 1NS5A 4YQ6A 4X3MA 1V6ZA 4KGNA 5CO4A 3OIIA 2V3JA 2QWVA 4MCBA 4JAKA 3O7BA 3DCMX 4PZKA 4YVHA 4MCCA 4YVKA 1VH0A 1MXIA 1X7OA 3AIAA 4YQJA 4YQ3A 4CNFA 4YQ8A 3AXZA 1VHKA 5GMCA 1OY5A 4YQNA 3BBDA 3BBHA 4FAKA 4YQIA 4E8BA 3QUVA
chains in the Genus database with same CATH superfamily
1K3RA 4YQQA 4YQOA 4YQPA 1TROA 4YQTA 2CX8A 3N4JA 3OIJA 4YQ1A 2O3AA 5GM8A 3BBEA 2QMMA 1ZJRA 3AI9X 4H3YA 1VHYA 2EGVA 4XBOA 4YQRA 4YPYA 2V3KA 4JWGA 3IEFA 3KTYA 1GZ0A 4J3CA 2I6DA 3N4KA 4YVIA 3L8UA 4YQSA 4YQKA 1WRSR 4YQGA 1WRPR 1CO0A 3IC6A 5GMBA 1NXZA 2Z0YA 3KNUA 3ILKA 4H3ZA 1MI7R 4YQAA 1UALA 1P9PA 4L69A 1UAKA 2OZ9R 3OINA 4CNGA 1TO0A 1TRRA 1Z85A 1V2XA 2YY8A 4YQ9A 1X7PA 1UAJA 4CNDA 4YPZA 1J85A 1RCSA 3KW2A 4YQCA 4FMWA 3ONPA 4JWJA 4RG1A 4IG6A 3WRPA 4YQ5A 4YVJA 4YPXA 1ZT9A 3SSXN 4YQBA 1IPAA 4YQ4A 4KDZA 4YQLA 4YPWA 4YQ7A 5FAIA 2EGWA 3E5YA 3KORA 3KY7A 2HA8A 3SSWN 3NK6A 3NK7A 1UAMA 3GYQA 4CNEA 4JWHA 4YQ2A 4JALA 4YQDA 1O6DA 5D9FA 4YVGA 4MCDA 4YQ0A 4X3LA 1NS5A 4YQ6A 4JWFA 4X3MA 1V6ZA 4KGNA 5CO4A 1WRTR 2V3JA 3OIIA 2QWVA 4MCBA 3FRWA 4JAKA 3O7BA 3DCMX 4PZKA 4YVHA 4MCCA 1JHGA 4YVKA 1VH0A 1MXIA 1X7OA 3AIAA 4YQJA 4YQ3A 4CNFA 4YQ8A 3AXZA 2XDIA 1VHKA 5GMCA 1OY5A 4YQNA 3BBDA 3BBHA 4FAKA 4YQIA 4E8BA 3QUVA 3G1CA
chains in the Genus database with same CATH topology
1K3RA 4YQQA 4YQOA 4YQPA 4YQTA 2CX8A 3N4JA 3OIJA 4YQ1A 2O3AA 5GM8A 3BBEA 2QMMA 1ZJRA 3AI9X 4H3YA 1VHYA 2EGVA 4XBOA 4YQRA 4YPYA 2V3KA 4JWGA 3IEFA 3KTYA 1GZ0A 4J3CA 2I6DA 3N4KA 4YVIA 3L8UA 4YQSA 4YQKA 4YQGA 3IC6A 5GMBA 1NXZA 2Z0YA 3KNUA 3ILKA 4H3ZA 4YQAA 1UALA 1P9PA 4L69A 1UAKA 3OINA 4CNGA 1TO0A 1Z85A 1V2XA 2YY8A 4YQ9A 1X7PA 1UAJA 4CNDA 4YPZA 1J85A 3KW2A 4YQCA 4FMWA 3ONPA 4JWJA 4RG1A 4IG6A 4YQ5A 4YVJA 4YPXA 4YQBA 1IPAA 4YQ4A 4KDZA 4YQLA 4YPWA 4YQ7A 5FAIA 2EGWA 3E5YA 3KY7A 2HA8A 3NK6A 4CNEA 3NK7A 1UAMA 3GYQA 4JWHA 4YQ2A 4JALA 4YQDA 1O6DA 5D9FA 4YVGA 4MCDA 4YQ0A 4X3LA 1NS5A 4YQ6A 4JWFA 4X3MA 1V6ZA 4KGNA 5CO4A 3OIIA 2V3JA 2QWVA 4MCBA 4JAKA 3O7BA 3DCMX 4PZKA 4YVHA 4MCCA 4YVKA 1VH0A 1MXIA 1X7OA 3AIAA 4YQJA 4YQ3A 4CNFA 4YQ8A 3AXZA 1VHKA 5GMCA 1OY5A 4YQNA 3BBDA 3BBHA 4FAKA 4YQIA 4E8BA 3QUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K3R A;  4YQQ A;  4YQO A;  4YQP A;  4YQT A;  2CX8 A;  3N4J A;  3OIJ A;  4YQ1 A;  2O3A A;  5GM8 A;  3BBE A;  2QMM A;  1ZJR A;  3AI9 X;  4H3Y A;  1VHY A;  2EGV A;  4XBO A;  4YQR A;  4YPY A;  2V3K A;  3IEF A;  3KTY A;  1GZ0 A;  4J3C A;  2I6D A;  3N4K A;  4YVI A;  3L8U A;  4YQS A;  4YQK A;  4YQG A;  3IC6 A;  5GMB A;  1NXZ A;  2Z0Y A;  3KNU A;  3ILK A;  4H3Z A;  4YQA A;  1UAL A;  1P9P A;  4L69 A;  1UAK A;  3OIN A;  4CNG A;  1TO0 A;  1Z85 A;  1V2X A;  2YY8 A;  4YQ9 A;  1X7P A;  1UAJ A;  4CND A;  4YPZ A;  1J85 A;  3KW2 A;  4YQC A;  3ONP A;  4RG1 A;  4IG6 A;  4YQ5 A;  4YVJ A;  4YPX A;  4YQB A;  1IPA A;  4YQ4 A;  4KDZ A;  4YQL A;  4YPW A;  4YQ7 A;  5FAI A;  2EGW A;  3E5Y A;  3KY7 A;  2HA8 A;  3NK6 A;  4CNE A;  3NK7 A;  1UAM A;  3GYQ A;  4YQ2 A;  4JAL A;  4YQD A;  1O6D A;  5D9F A;  4YVG A;  4MCD A;  4YQ0 A;  4X3L A;  1NS5 A;  4YQ6 A;  4X3M A;  1V6Z A;  4KGN A;  5CO4 A;  3OII A;  2V3J A;  2QWV A;  4MCB A;  4JAK A;  3O7B A;  3DCM X;  4PZK A;  4YVH A;  4MCC A;  4YVK A;  1VH0 A;  1MXI A;  1X7O A;  3AIA A;  4YQJ A;  4YQ3 A;  4CNF A;  4YQ8 A;  3AXZ A;  1VHK A;  5GMC A;  1OY5 A;  4YQN A;  3BBD A;  3BBH A;  4FAK A;  4YQI A;  4E8B A;  3QUV A; 
#chains in the Genus database with same CATH topology
 1K3R A;  4YQQ A;  4YQO A;  4YQP A;  1TRO A;  4YQT A;  2CX8 A;  3N4J A;  3OIJ A;  4YQ1 A;  2O3A A;  5GM8 A;  3BBE A;  2QMM A;  1ZJR A;  3AI9 X;  4H3Y A;  1VHY A;  2EGV A;  4XBO A;  4YQR A;  4YPY A;  2V3K A;  4JWG A;  3IEF A;  3KTY A;  1GZ0 A;  4J3C A;  2I6D A;  3N4K A;  4YVI A;  3L8U A;  4YQS A;  4YQK A;  1WRS R;  4YQG A;  1WRP R;  1CO0 A;  3IC6 A;  5GMB A;  1NXZ A;  2Z0Y A;  3KNU A;  3ILK A;  4H3Z A;  1MI7 R;  4YQA A;  1UAL A;  1P9P A;  4L69 A;  1UAK A;  2OZ9 R;  3OIN A;  4CNG A;  1TO0 A;  1TRR A;  1Z85 A;  1V2X A;  2YY8 A;  4YQ9 A;  1X7P A;  1UAJ A;  4CND A;  4YPZ A;  1J85 A;  1RCS A;  3KW2 A;  4YQC A;  4FMW A;  3ONP A;  4JWJ A;  4RG1 A;  4IG6 A;  3WRP A;  4YQ5 A;  4YVJ A;  4YPX A;  1ZT9 A;  3SSX N;  4YQB A;  1IPA A;  4YQ4 A;  4KDZ A;  4YQL A;  4YPW A;  4YQ7 A;  5FAI A;  2EGW A;  3E5Y A;  3KOR A;  3KY7 A;  2HA8 A;  3SSW N;  3NK6 A;  3NK7 A;  1UAM A;  3GYQ A;  4CNE A;  4JWH A;  4YQ2 A;  4JAL A;  4YQD A;  1O6D A;  5D9F A;  4YVG A;  4MCD A;  4YQ0 A;  4X3L A;  1NS5 A;  4YQ6 A;  4JWF A;  4X3M A;  1V6Z A;  4KGN A;  5CO4 A;  1WRT R;  2V3J A;  3OII A;  2QWV A;  4MCB A;  3FRW A;  4JAK A;  3O7B A;  3DCM X;  4PZK A;  4YVH A;  4MCC A;  1JHG A;  4YVK A;  1VH0 A;  1MXI A;  1X7O A;  3AIA A;  4YQJ A;  4YQ3 A;  4CNF A;  4YQ8 A;  3AXZ A;  2XDI A;  1VHK A;  5GMC A;  1OY5 A;  4YQN A;  3BBD A;  3BBH A;  4FAK A;  4YQI A;  4E8B A;  3QUV A;  3G1C A; 
#chains in the Genus database with same CATH homology
 1K3R A;  4YQQ A;  4YQO A;  4YQP A;  4YQT A;  2CX8 A;  3N4J A;  3OIJ A;  4YQ1 A;  2O3A A;  5GM8 A;  3BBE A;  2QMM A;  1ZJR A;  3AI9 X;  4H3Y A;  1VHY A;  2EGV A;  4XBO A;  4YQR A;  4YPY A;  2V3K A;  4JWG A;  3IEF A;  3KTY A;  1GZ0 A;  4J3C A;  2I6D A;  3N4K A;  4YVI A;  3L8U A;  4YQS A;  4YQK A;  4YQG A;  3IC6 A;  5GMB A;  1NXZ A;  2Z0Y A;  3KNU A;  3ILK A;  4H3Z A;  4YQA A;  1UAL A;  1P9P A;  4L69 A;  1UAK A;  3OIN A;  4CNG A;  1TO0 A;  1Z85 A;  1V2X A;  2YY8 A;  4YQ9 A;  1X7P A;  1UAJ A;  4CND A;  4YPZ A;  1J85 A;  3KW2 A;  4YQC A;  4FMW A;  3ONP A;  4JWJ A;  4RG1 A;  4IG6 A;  4YQ5 A;  4YVJ A;  4YPX A;  4YQB A;  1IPA A;  4YQ4 A;  4KDZ A;  4YQL A;  4YPW A;  4YQ7 A;  5FAI A;  2EGW A;  3E5Y A;  3KY7 A;  2HA8 A;  3NK6 A;  4CNE A;  3NK7 A;  1UAM A;  3GYQ A;  4JWH A;  4YQ2 A;  4JAL A;  4YQD A;  1O6D A;  5D9F A;  4YVG A;  4MCD A;  4YQ0 A;  4X3L A;  1NS5 A;  4YQ6 A;  4JWF A;  4X3M A;  1V6Z A;  4KGN A;  5CO4 A;  3OII A;  2V3J A;  2QWV A;  4MCB A;  4JAK A;  3O7B A;  3DCM X;  4PZK A;  4YVH A;  4MCC A;  4YVK A;  1VH0 A;  1MXI A;  1X7O A;  3AIA A;  4YQJ A;  4YQ3 A;  4CNF A;  4YQ8 A;  3AXZ A;  1VHK A;  5GMC A;  1OY5 A;  4YQN A;  3BBD A;  3BBH A;  4FAK A;  4YQI A;  4E8B A;  3QUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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