4YQLA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
248
structure length
240
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 240
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqlA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqlA01
4YPZA 4YQBA 4KDZA 1VHYA 3ILKA 4YQ8A 3OIIA 3KTYA 4XBOA 4CNEA 4L69A 4YQJA 4YVIA 4YQTA 3ONPA 4MCBA 4YQCA 3GYQA 2QWVA 1ZJRA 5GMCA 1GZ0A 1MXIA 3N4KA 1UAJA 4YQGA 5FAIA 5GM8A 4MCCA 1VH0A 3OIJA 2EGVA 4JALA 4MCDA 4YQ0A 1UAMA 4YVKA 1IPAA 1X7OA 4CNFA 4YQOA 3NK6A 2Z0YA 1X7PA 4YPWA 1TO0A 4YQ4A 5CO4A 3E5YA 3IC6A 4YPYA 1UAKA 4YQKA 4YQ3A 1V2XA 4YQSA 3DCMX 4FAKA 4YQPA 3AI9X 4X3LA 3AIAA 4CNGA 2CX8A 4H3ZA 2V3JA 4E8BA 3BBEA 2I6DA 3KNUA 4J3CA 2EGWA 3NK7A 4YQDA 4YQIA 1OY5A 4YVHA 5D9FA 3AXZA 3BBHA 1UALA 3QUVA 2YY8A 3L8UA 3BBDA 3O7BA 4YQ5A 4H3YA 1NS5A 1K3RA 1Z85A 3IEFA 3N4JA 4X3MA 1NXZA 3KW2A 4KGNA 4PZKA 2HA8A 1P9PA 3OINA 4YQ9A 1J85A 4YQ1A 1O6DA 4IG6A 5GMBA 4YQRA 4YQLA 4YPXA 1V6ZA 3KY7A 4YQ7A 4YQNA 4YQAA 2V3KA 4JAKA 4RG1A 4YVJA 4YVGA 4YQ6A 4YQQA 1VHKA 2O3AA 2QMMA 4YQ2A 4CNDA
chains in the Genus database with same CATH superfamily
4YPZA 4YQBA 4KDZA 2OZ9R 1VHYA 3ILKA 4FMWA 3FRWA 4YQ8A 3OIIA 3KTYA 4XBOA 4CNEA 4L69A 4YQJA 1ZT9A 4YVIA 4YQTA 3SSXN 3ONPA 4JWJA 4MCBA 4YQCA 3KORA 1JHGA 3GYQA 2QWVA 1ZJRA 5GMCA 1GZ0A 1MXIA 3N4KA 1UAJA 4YQGA 5FAIA 3SSWN 5GM8A 1WRSR 4MCCA 1VH0A 3OIJA 2EGVA 1TRRA 4JALA 1MI7R 4MCDA 4YQ0A 1UAMA 4YVKA 1IPAA 1X7OA 4CNFA 4YQOA 3NK6A 2Z0YA 1X7PA 4YPWA 1TO0A 4YQ4A 5CO4A 3E5YA 3IC6A 4YPYA 1UAKA 1CO0A 4YQKA 4YQ3A 1V2XA 4YQSA 3DCMX 4FAKA 4YQPA 3AI9X 4X3LA 3AIAA 4CNGA 1RCSA 1WRPR 2CX8A 4H3ZA 2V3JA 4E8BA 3BBEA 4JWFA 2I6DA 4JWHA 3KNUA 4J3CA 2EGWA 3NK7A 4YQDA 4YQIA 1OY5A 4YVHA 5D9FA 3AXZA 3BBHA 1UALA 3QUVA 2YY8A 3L8UA 3BBDA 4JWGA 3O7BA 4YQ5A 4H3YA 1WRTR 1NS5A 1K3RA 1Z85A 3IEFA 3N4JA 3WRPA 4X3MA 1NXZA 3G1CA 3KW2A 4KGNA 4PZKA 2HA8A 1P9PA 3OINA 4YQ9A 1J85A 4YQ1A 1O6DA 4IG6A 5GMBA 4YQRA 4YQLA 4YPXA 1V6ZA 3KY7A 4YQ7A 4YQNA 4YQAA 2V3KA 4JAKA 4RG1A 1TROA 4YVJA 4YVGA 4YQ6A 4YQQA 1VHKA 2O3AA 2QMMA 4YQ2A 4CNDA 2XDIA
chains in the Genus database with same CATH topology
4YPZA 4YQBA 4KDZA 1VHYA 3ILKA 4FMWA 4YQ8A 3OIIA 3KTYA 4XBOA 4CNEA 4L69A 4YQJA 4YVIA 4YQTA 3ONPA 4JWJA 4MCBA 4YQCA 3GYQA 2QWVA 1ZJRA 5GMCA 1GZ0A 1MXIA 3N4KA 1UAJA 4YQGA 5FAIA 5GM8A 4MCCA 1VH0A 3OIJA 2EGVA 4JALA 4MCDA 4YQ0A 1UAMA 4YVKA 1IPAA 1X7OA 4CNFA 4YQOA 3NK6A 2Z0YA 1X7PA 4YPWA 1TO0A 4YQ4A 5CO4A 3E5YA 3IC6A 4YPYA 1UAKA 4YQKA 4YQ3A 1V2XA 4YQSA 3DCMX 4FAKA 4YQPA 3AI9X 4X3LA 3AIAA 4CNGA 2CX8A 4H3ZA 2V3JA 4E8BA 3BBEA 4JWFA 2I6DA 4JWHA 3KNUA 4J3CA 2EGWA 3NK7A 4YQDA 4YQIA 1OY5A 4YVHA 5D9FA 3AXZA 3BBHA 1UALA 3QUVA 2YY8A 3L8UA 3BBDA 4JWGA 3O7BA 4YQ5A 4H3YA 1NS5A 1K3RA 1Z85A 3IEFA 3N4JA 4X3MA 1NXZA 3KW2A 4KGNA 4PZKA 2HA8A 1P9PA 3OINA 4YQ9A 1J85A 4YQ1A 1O6DA 4IG6A 5GMBA 4YQRA 4YQLA 4YPXA 1V6ZA 3KY7A 4YQ7A 4YQNA 4YQAA 2V3KA 4JAKA 4RG1A 4YVJA 4YVGA 4YQ6A 4YQQA 1VHKA 2O3AA 2QMMA 4YQ2A 4CNDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPZ A;  4YQB A;  4KDZ A;  1VHY A;  3ILK A;  4YQ8 A;  3OII A;  3KTY A;  4XBO A;  4CNE A;  4L69 A;  4YQJ A;  4YVI A;  4YQT A;  3ONP A;  4MCB A;  4YQC A;  3GYQ A;  2QWV A;  1ZJR A;  5GMC A;  1GZ0 A;  1MXI A;  3N4K A;  1UAJ A;  4YQG A;  5FAI A;  5GM8 A;  4MCC A;  1VH0 A;  3OIJ A;  2EGV A;  4JAL A;  4MCD A;  4YQ0 A;  1UAM A;  4YVK A;  1IPA A;  1X7O A;  4CNF A;  4YQO A;  3NK6 A;  2Z0Y A;  1X7P A;  4YPW A;  1TO0 A;  4YQ4 A;  5CO4 A;  3E5Y A;  3IC6 A;  4YPY A;  1UAK A;  4YQK A;  4YQ3 A;  1V2X A;  4YQS A;  3DCM X;  4FAK A;  4YQP A;  3AI9 X;  4X3L A;  3AIA A;  4CNG A;  2CX8 A;  4H3Z A;  2V3J A;  4E8B A;  3BBE A;  2I6D A;  3KNU A;  4J3C A;  2EGW A;  3NK7 A;  4YQD A;  4YQI A;  1OY5 A;  4YVH A;  5D9F A;  3AXZ A;  3BBH A;  1UAL A;  3QUV A;  2YY8 A;  3L8U A;  3BBD A;  3O7B A;  4YQ5 A;  4H3Y A;  1NS5 A;  1K3R A;  1Z85 A;  3IEF A;  3N4J A;  4X3M A;  1NXZ A;  3KW2 A;  4KGN A;  4PZK A;  2HA8 A;  1P9P A;  3OIN A;  4YQ9 A;  1J85 A;  4YQ1 A;  1O6D A;  4IG6 A;  5GMB A;  4YQR A;  4YQL A;  4YPX A;  1V6Z A;  3KY7 A;  4YQ7 A;  4YQN A;  4YQA A;  2V3K A;  4JAK A;  4RG1 A;  4YVJ A;  4YVG A;  4YQ6 A;  4YQQ A;  1VHK A;  2O3A A;  2QMM A;  4YQ2 A;  4CND A; 
#chains in the Genus database with same CATH topology
 4YPZ A;  4YQB A;  4KDZ A;  2OZ9 R;  1VHY A;  3ILK A;  4FMW A;  3FRW A;  4YQ8 A;  3OII A;  3KTY A;  4XBO A;  4CNE A;  4L69 A;  4YQJ A;  1ZT9 A;  4YVI A;  4YQT A;  3SSX N;  3ONP A;  4JWJ A;  4MCB A;  4YQC A;  3KOR A;  1JHG A;  3GYQ A;  2QWV A;  1ZJR A;  5GMC A;  1GZ0 A;  1MXI A;  3N4K A;  1UAJ A;  4YQG A;  5FAI A;  3SSW N;  5GM8 A;  1WRS R;  4MCC A;  1VH0 A;  3OIJ A;  2EGV A;  1TRR A;  4JAL A;  1MI7 R;  4MCD A;  4YQ0 A;  1UAM A;  4YVK A;  1IPA A;  1X7O A;  4CNF A;  4YQO A;  3NK6 A;  2Z0Y A;  1X7P A;  4YPW A;  1TO0 A;  4YQ4 A;  5CO4 A;  3E5Y A;  3IC6 A;  4YPY A;  1UAK A;  1CO0 A;  4YQK A;  4YQ3 A;  1V2X A;  4YQS A;  3DCM X;  4FAK A;  4YQP A;  3AI9 X;  4X3L A;  3AIA A;  4CNG A;  1RCS A;  1WRP R;  2CX8 A;  4H3Z A;  2V3J A;  4E8B A;  3BBE A;  4JWF A;  2I6D A;  4JWH A;  3KNU A;  4J3C A;  2EGW A;  3NK7 A;  4YQD A;  4YQI A;  1OY5 A;  4YVH A;  5D9F A;  3AXZ A;  3BBH A;  1UAL A;  3QUV A;  2YY8 A;  3L8U A;  3BBD A;  4JWG A;  3O7B A;  4YQ5 A;  4H3Y A;  1WRT R;  1NS5 A;  1K3R A;  1Z85 A;  3IEF A;  3N4J A;  3WRP A;  4X3M A;  1NXZ A;  3G1C A;  3KW2 A;  4KGN A;  4PZK A;  2HA8 A;  1P9P A;  3OIN A;  4YQ9 A;  1J85 A;  4YQ1 A;  1O6D A;  4IG6 A;  5GMB A;  4YQR A;  4YQL A;  4YPX A;  1V6Z A;  3KY7 A;  4YQ7 A;  4YQN A;  4YQA A;  2V3K A;  4JAK A;  4RG1 A;  1TRO A;  4YVJ A;  4YVG A;  4YQ6 A;  4YQQ A;  1VHK A;  2O3A A;  2QMM A;  4YQ2 A;  4CND A;  2XDI A; 
#chains in the Genus database with same CATH homology
 4YPZ A;  4YQB A;  4KDZ A;  1VHY A;  3ILK A;  4FMW A;  4YQ8 A;  3OII A;  3KTY A;  4XBO A;  4CNE A;  4L69 A;  4YQJ A;  4YVI A;  4YQT A;  3ONP A;  4JWJ A;  4MCB A;  4YQC A;  3GYQ A;  2QWV A;  1ZJR A;  5GMC A;  1GZ0 A;  1MXI A;  3N4K A;  1UAJ A;  4YQG A;  5FAI A;  5GM8 A;  4MCC A;  1VH0 A;  3OIJ A;  2EGV A;  4JAL A;  4MCD A;  4YQ0 A;  1UAM A;  4YVK A;  1IPA A;  1X7O A;  4CNF A;  4YQO A;  3NK6 A;  2Z0Y A;  1X7P A;  4YPW A;  1TO0 A;  4YQ4 A;  5CO4 A;  3E5Y A;  3IC6 A;  4YPY A;  1UAK A;  4YQK A;  4YQ3 A;  1V2X A;  4YQS A;  3DCM X;  4FAK A;  4YQP A;  3AI9 X;  4X3L A;  3AIA A;  4CNG A;  2CX8 A;  4H3Z A;  2V3J A;  4E8B A;  3BBE A;  4JWF A;  2I6D A;  4JWH A;  3KNU A;  4J3C A;  2EGW A;  3NK7 A;  4YQD A;  4YQI A;  1OY5 A;  4YVH A;  5D9F A;  3AXZ A;  3BBH A;  1UAL A;  3QUV A;  2YY8 A;  3L8U A;  3BBD A;  4JWG A;  3O7B A;  4YQ5 A;  4H3Y A;  1NS5 A;  1K3R A;  1Z85 A;  3IEF A;  3N4J A;  4X3M A;  1NXZ A;  3KW2 A;  4KGN A;  4PZK A;  2HA8 A;  1P9P A;  3OIN A;  4YQ9 A;  1J85 A;  4YQ1 A;  1O6D A;  4IG6 A;  5GMB A;  4YQR A;  4YQL A;  4YPX A;  1V6Z A;  3KY7 A;  4YQ7 A;  4YQN A;  4YQA A;  2V3K A;  4JAK A;  4RG1 A;  4YVJ A;  4YVG A;  4YQ6 A;  4YQQ A;  1VHK A;  2O3A A;  2QMM A;  4YQ2 A;  4CND A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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