4YQLA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
248
structure length
240
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 240
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqlA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqlA01
1UAMA 4YPYA 4E8BA 4FAKA 4YQBA 2Z0YA 3N4KA 4YVKA 4YQAA 1VHKA 3OIIA 3IC6A 1P9PA 4YQQA 1ZJRA 3AXZA 1GZ0A 4H3ZA 4YQNA 3QUVA 4YVIA 3BBEA 4YQ6A 3O7BA 2QMMA 4YQOA 3BBHA 1O6DA 1NXZA 1UAJA 4YVGA 4YQ4A 1Z85A 2HA8A 1UALA 1VHYA 5CO4A 1X7PA 3OINA 3KTYA 4IG6A 3GYQA 3N4JA 3E5YA 3ONPA 1X7OA 2O3AA 4MCCA 5GMCA 1IPAA 2V3KA 4YQ9A 3KNUA 3L8UA 2I6DA 2CX8A 4CNDA 4PZKA 2EGVA 3NK7A 4YQTA 1V6ZA 4YPZA 2EGWA 1K3RA 1OY5A 1J85A 5D9FA 4RG1A 5GM8A 4YVJA 3KY7A 1V2XA 4H3YA 4YQ3A 4X3LA 4JALA 4X3MA 4XBOA 4YQ8A 4YQIA 4YQSA 4YQ5A 4MCDA 4JAKA 1TO0A 3NK6A 4CNGA 1VH0A 3AIAA 4YQKA 4YQ1A 3BBDA 2QWVA 3ILKA 3KW2A 4J3CA 4CNEA 4YQ2A 4KDZA 3AI9X 1UAKA 3DCMX 1MXIA 4YQRA 4YQJA 3IEFA 4YQDA 4YQ0A 1NS5A 4KGNA 4YQ7A 4YQPA 4YPWA 5FAIA 5GMBA 2V3JA 4L69A 2YY8A 4YQLA 4MCBA 4CNFA 4YQCA 4YQGA 4YVHA 4YPXA 3OIJA
chains in the Genus database with same CATH superfamily
1UAMA 4YPYA 4E8BA 2XDIA 4FAKA 4YQBA 2Z0YA 3N4KA 1TROA 4YVKA 4YQAA 1VHKA 3OIIA 3IC6A 3SSWN 1P9PA 4YQQA 1ZJRA 3AXZA 4FMWA 1GZ0A 4H3ZA 4YQNA 3QUVA 4YVIA 1CO0A 3BBEA 4YQ6A 3O7BA 2QMMA 4YQOA 3BBHA 1NXZA 1O6DA 1UAJA 4YVGA 4YQ4A 1RCSA 1Z85A 2HA8A 1UALA 3SSXN 1VHYA 5CO4A 1X7PA 3OINA 3KTYA 4IG6A 3GYQA 3N4JA 3E5YA 3ONPA 1X7OA 2O3AA 4MCCA 3FRWA 5GMCA 4JWGA 1IPAA 2V3KA 4YQ9A 3KNUA 3L8UA 1TRRA 3G1CA 2I6DA 2CX8A 4CNDA 4PZKA 2EGVA 3NK7A 4YQTA 1V6ZA 1WRTR 4YPZA 2EGWA 1K3RA 1OY5A 2OZ9R 1J85A 5D9FA 1ZT9A 4RG1A 5GM8A 4YVJA 3WRPA 3KY7A 3KORA 1V2XA 4H3YA 4YQ3A 4X3LA 4JALA 4X3MA 4JWFA 4YQ8A 4YQIA 4XBOA 4YQSA 4YQ5A 4MCDA 4JAKA 1TO0A 3NK6A 4CNGA 1VH0A 3AIAA 4YQKA 4YQ1A 3BBDA 2QWVA 3ILKA 3KW2A 4J3CA 4CNEA 4YQ2A 4KDZA 4JWHA 3AI9X 1UAKA 3DCMX 1MXIA 4YQRA 4YQJA 1MI7R 4JWJA 1JHGA 3IEFA 4YQDA 4YQ0A 1NS5A 4KGNA 4YQ7A 4YQPA 4YPWA 5FAIA 5GMBA 2V3JA 4L69A 2YY8A 1WRPR 1WRSR 4MCBA 4YQCA 4YQLA 4CNFA 4YQGA 4YVHA 4YPXA 3OIJA
chains in the Genus database with same CATH topology
1UAMA 4YPYA 4E8BA 4FAKA 4YQBA 2Z0YA 3N4KA 4YVKA 4YQAA 1VHKA 3OIIA 3IC6A 1P9PA 4YQQA 1ZJRA 3AXZA 4FMWA 1GZ0A 4H3ZA 4YQNA 3QUVA 4YVIA 3BBEA 4YQ6A 3O7BA 2QMMA 4YQOA 3BBHA 1O6DA 1NXZA 1UAJA 4YVGA 4YQ4A 1Z85A 2HA8A 1UALA 1VHYA 5CO4A 1X7PA 3OINA 3KTYA 4IG6A 3GYQA 3N4JA 3E5YA 3ONPA 1X7OA 2O3AA 4MCCA 5GMCA 4JWGA 1IPAA 2V3KA 4YQ9A 3KNUA 3L8UA 2I6DA 2CX8A 4CNDA 4PZKA 2EGVA 3NK7A 4YQTA 1V6ZA 4YPZA 2EGWA 1K3RA 1OY5A 1J85A 5D9FA 4RG1A 5GM8A 4YVJA 3KY7A 1V2XA 4H3YA 4YQ3A 4X3LA 4JALA 4X3MA 4JWFA 4YQ8A 4YQIA 4XBOA 4YQSA 4YQ5A 4MCDA 4JAKA 1TO0A 3NK6A 4CNGA 1VH0A 3AIAA 4YQKA 4YQ1A 3BBDA 2QWVA 3ILKA 3KW2A 4J3CA 4CNEA 4YQ2A 4KDZA 4JWHA 3AI9X 1UAKA 3DCMX 1MXIA 4YQRA 4YQJA 4JWJA 3IEFA 4YQDA 4YQ0A 1NS5A 4KGNA 4YQ7A 4YQPA 4YPWA 5FAIA 5GMBA 2V3JA 4L69A 2YY8A 4YQLA 4MCBA 4CNFA 4YQCA 4YQGA 4YVHA 4YPXA 3OIJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UAM A;  4YPY A;  4E8B A;  4FAK A;  4YQB A;  2Z0Y A;  3N4K A;  4YVK A;  4YQA A;  1VHK A;  3OII A;  3IC6 A;  1P9P A;  4YQQ A;  1ZJR A;  3AXZ A;  1GZ0 A;  4H3Z A;  4YQN A;  3QUV A;  4YVI A;  3BBE A;  4YQ6 A;  3O7B A;  2QMM A;  4YQO A;  3BBH A;  1O6D A;  1NXZ A;  1UAJ A;  4YVG A;  4YQ4 A;  1Z85 A;  2HA8 A;  1UAL A;  1VHY A;  5CO4 A;  1X7P A;  3OIN A;  3KTY A;  4IG6 A;  3GYQ A;  3N4J A;  3E5Y A;  3ONP A;  1X7O A;  2O3A A;  4MCC A;  5GMC A;  1IPA A;  2V3K A;  4YQ9 A;  3KNU A;  3L8U A;  2I6D A;  2CX8 A;  4CND A;  4PZK A;  2EGV A;  3NK7 A;  4YQT A;  1V6Z A;  4YPZ A;  2EGW A;  1K3R A;  1OY5 A;  1J85 A;  5D9F A;  4RG1 A;  5GM8 A;  4YVJ A;  3KY7 A;  1V2X A;  4H3Y A;  4YQ3 A;  4X3L A;  4JAL A;  4X3M A;  4XBO A;  4YQ8 A;  4YQI A;  4YQS A;  4YQ5 A;  4MCD A;  4JAK A;  1TO0 A;  3NK6 A;  4CNG A;  1VH0 A;  3AIA A;  4YQK A;  4YQ1 A;  3BBD A;  2QWV A;  3ILK A;  3KW2 A;  4J3C A;  4CNE A;  4YQ2 A;  4KDZ A;  3AI9 X;  1UAK A;  3DCM X;  1MXI A;  4YQR A;  4YQJ A;  3IEF A;  4YQD A;  4YQ0 A;  1NS5 A;  4KGN A;  4YQ7 A;  4YQP A;  4YPW A;  5FAI A;  5GMB A;  2V3J A;  4L69 A;  2YY8 A;  4YQL A;  4MCB A;  4CNF A;  4YQC A;  4YQG A;  4YVH A;  4YPX A;  3OIJ A; 
#chains in the Genus database with same CATH topology
 1UAM A;  4YPY A;  4E8B A;  2XDI A;  4FAK A;  4YQB A;  2Z0Y A;  3N4K A;  1TRO A;  4YVK A;  4YQA A;  1VHK A;  3OII A;  3IC6 A;  3SSW N;  1P9P A;  4YQQ A;  1ZJR A;  3AXZ A;  4FMW A;  1GZ0 A;  4H3Z A;  4YQN A;  3QUV A;  4YVI A;  1CO0 A;  3BBE A;  4YQ6 A;  3O7B A;  2QMM A;  4YQO A;  3BBH A;  1NXZ A;  1O6D A;  1UAJ A;  4YVG A;  4YQ4 A;  1RCS A;  1Z85 A;  2HA8 A;  1UAL A;  3SSX N;  1VHY A;  5CO4 A;  1X7P A;  3OIN A;  3KTY A;  4IG6 A;  3GYQ A;  3N4J A;  3E5Y A;  3ONP A;  1X7O A;  2O3A A;  4MCC A;  3FRW A;  5GMC A;  4JWG A;  1IPA A;  2V3K A;  4YQ9 A;  3KNU A;  3L8U A;  1TRR A;  3G1C A;  2I6D A;  2CX8 A;  4CND A;  4PZK A;  2EGV A;  3NK7 A;  4YQT A;  1V6Z A;  1WRT R;  4YPZ A;  2EGW A;  1K3R A;  1OY5 A;  2OZ9 R;  1J85 A;  5D9F A;  1ZT9 A;  4RG1 A;  5GM8 A;  4YVJ A;  3WRP A;  3KY7 A;  3KOR A;  1V2X A;  4H3Y A;  4YQ3 A;  4X3L A;  4JAL A;  4X3M A;  4JWF A;  4YQ8 A;  4YQI A;  4XBO A;  4YQS A;  4YQ5 A;  4MCD A;  4JAK A;  1TO0 A;  3NK6 A;  4CNG A;  1VH0 A;  3AIA A;  4YQK A;  4YQ1 A;  3BBD A;  2QWV A;  3ILK A;  3KW2 A;  4J3C A;  4CNE A;  4YQ2 A;  4KDZ A;  4JWH A;  3AI9 X;  1UAK A;  3DCM X;  1MXI A;  4YQR A;  4YQJ A;  1MI7 R;  4JWJ A;  1JHG A;  3IEF A;  4YQD A;  4YQ0 A;  1NS5 A;  4KGN A;  4YQ7 A;  4YQP A;  4YPW A;  5FAI A;  5GMB A;  2V3J A;  4L69 A;  2YY8 A;  1WRP R;  1WRS R;  4MCB A;  4YQC A;  4YQL A;  4CNF A;  4YQG A;  4YVH A;  4YPX A;  3OIJ A; 
#chains in the Genus database with same CATH homology
 1UAM A;  4YPY A;  4E8B A;  4FAK A;  4YQB A;  2Z0Y A;  3N4K A;  4YVK A;  4YQA A;  1VHK A;  3OII A;  3IC6 A;  1P9P A;  4YQQ A;  1ZJR A;  3AXZ A;  4FMW A;  1GZ0 A;  4H3Z A;  4YQN A;  3QUV A;  4YVI A;  3BBE A;  4YQ6 A;  3O7B A;  2QMM A;  4YQO A;  3BBH A;  1O6D A;  1NXZ A;  1UAJ A;  4YVG A;  4YQ4 A;  1Z85 A;  2HA8 A;  1UAL A;  1VHY A;  5CO4 A;  1X7P A;  3OIN A;  3KTY A;  4IG6 A;  3GYQ A;  3N4J A;  3E5Y A;  3ONP A;  1X7O A;  2O3A A;  4MCC A;  5GMC A;  4JWG A;  1IPA A;  2V3K A;  4YQ9 A;  3KNU A;  3L8U A;  2I6D A;  2CX8 A;  4CND A;  4PZK A;  2EGV A;  3NK7 A;  4YQT A;  1V6Z A;  4YPZ A;  2EGW A;  1K3R A;  1OY5 A;  1J85 A;  5D9F A;  4RG1 A;  5GM8 A;  4YVJ A;  3KY7 A;  1V2X A;  4H3Y A;  4YQ3 A;  4X3L A;  4JAL A;  4X3M A;  4JWF A;  4YQ8 A;  4YQI A;  4XBO A;  4YQS A;  4YQ5 A;  4MCD A;  4JAK A;  1TO0 A;  3NK6 A;  4CNG A;  1VH0 A;  3AIA A;  4YQK A;  4YQ1 A;  3BBD A;  2QWV A;  3ILK A;  3KW2 A;  4J3C A;  4CNE A;  4YQ2 A;  4KDZ A;  4JWH A;  3AI9 X;  1UAK A;  3DCM X;  1MXI A;  4YQR A;  4YQJ A;  4JWJ A;  3IEF A;  4YQD A;  4YQ0 A;  1NS5 A;  4KGN A;  4YQ7 A;  4YQP A;  4YPW A;  5FAI A;  5GMB A;  2V3J A;  4L69 A;  2YY8 A;  4YQL A;  4MCB A;  4CNF A;  4YQC A;  4YQG A;  4YVH A;  4YPX A;  3OIJ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...