4YQNA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
248
structure length
237
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqnA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqnA01
1X7PA 1UAJA 4YQJA 4JALA 2EGWA 1GZ0A 4YQ5A 2EGVA 4YQ9A 4YPZA 4YQLA 1V6ZA 3ONPA 3OIJA 4IG6A 4J3CA 4YQ1A 2V3KA 2QWVA 3ILKA 1P9PA 2QMMA 4YPXA 4YVIA 1Z85A 1OY5A 5GM8A 1X7OA 1ZJRA 1K3RA 3L8UA 2CX8A 3BBEA 4YVKA 3KY7A 4CNDA 2HA8A 5CO4A 5GMCA 4CNGA 4JAKA 1NS5A 1TO0A 4YQAA 4MCDA 3E5YA 4YQ0A 3KNUA 4YPWA 4YQ6A 3BBHA 1UALA 2Z0YA 3BBDA 3NK6A 4YPYA 4PZKA 3AI9X 4MCCA 1IPAA 1J85A 4YQSA 4E8BA 4YVGA 4YQRA 4RG1A 2V3JA 4FAKA 3KTYA 1VHYA 1V2XA 1UAMA 4YQOA 4YQ2A 4YQCA 4YQ8A 4YQDA 4YQTA 4YQIA 1VH0A 3KW2A 4MCBA 3N4KA 4H3ZA 4YQ7A 5D9FA 4YQ3A 4YVJA 5GMBA 3QUVA 1O6DA 3OINA 4X3LA 4YVHA 4YQQA 5FAIA 1VHKA 3AIAA 4XBOA 1MXIA 4CNEA 3AXZA 3O7BA 4YQKA 3DCMX 4YQBA 4KDZA 3IEFA 3IC6A 3NK7A 2I6DA 4YQ4A 4L69A 4YQNA 3GYQA 4CNFA 4KGNA 1NXZA 4H3YA 2YY8A 2O3AA 4YQPA 4X3MA 1UAKA 4YQGA 3N4JA 3OIIA
chains in the Genus database with same CATH superfamily
3KORA 1UAJA 4YQJA 1X7PA 4JALA 2EGWA 1GZ0A 4YQ5A 2EGVA 4YQ9A 4YPZA 4JWFA 4YQLA 1V6ZA 3ONPA 3OIJA 1MI7R 4IG6A 4J3CA 4YQ1A 1RCSA 2QWVA 2V3KA 3ILKA 1P9PA 2QMMA 4YPXA 4YVIA 1Z85A 1OY5A 5GM8A 1X7OA 1WRPR 1K3RA 1ZJRA 3L8UA 2CX8A 3BBEA 4YVKA 3KY7A 4CNDA 2HA8A 5CO4A 5GMCA 4CNGA 1JHGA 4JAKA 1NS5A 1TO0A 4YQAA 3FRWA 4MCDA 3E5YA 4YQ0A 1CO0A 3KNUA 4YPWA 4YQ6A 3BBHA 1UALA 2Z0YA 3BBDA 1TRRA 3NK6A 4YPYA 1ZT9A 4PZKA 3AI9X 4MCCA 1IPAA 1J85A 4YQSA 4E8BA 4YVGA 4YQRA 4RG1A 2V3JA 4FAKA 3KTYA 1VHYA 1UAMA 1V2XA 4YQOA 4YQ2A 4YQCA 4YQ8A 4YQDA 4YQTA 4YQIA 1VH0A 3KW2A 4MCBA 3N4KA 2OZ9R 4H3ZA 4YQ7A 5D9FA 4YQ3A 4YVJA 5GMBA 4JWJA 3QUVA 1O6DA 3WRPA 3OINA 4X3LA 4YVHA 4YQQA 5FAIA 1VHKA 3G1CA 3AIAA 4XBOA 1MXIA 4CNEA 3AXZA 3O7BA 4YQKA 3DCMX 4YQBA 4KDZA 4JWGA 3SSWN 1WRSR 3IEFA 3IC6A 3NK7A 3SSXN 2I6DA 4YQ4A 4L69A 1TROA 4YQNA 4JWHA 3GYQA 1WRTR 4CNFA 4KGNA 1NXZA 4H3YA 2YY8A 2XDIA 4YQPA 2O3AA 4FMWA 4X3MA 1UAKA 4YQGA 3N4JA 3OIIA
chains in the Genus database with same CATH topology
1X7PA 1UAJA 4YQJA 4JALA 2EGWA 1GZ0A 4YQ5A 2EGVA 4YQ9A 4YPZA 4JWFA 4YQLA 1V6ZA 3ONPA 3OIJA 4IG6A 4J3CA 4YQ1A 2V3KA 2QWVA 3ILKA 1P9PA 2QMMA 4YPXA 4YVIA 1Z85A 1OY5A 5GM8A 1X7OA 1ZJRA 1K3RA 3L8UA 2CX8A 3BBEA 4YVKA 3KY7A 4CNDA 2HA8A 5CO4A 5GMCA 4CNGA 4JAKA 1NS5A 1TO0A 4YQAA 4MCDA 3E5YA 4YQ0A 3KNUA 4YPWA 4YQ6A 3BBHA 1UALA 2Z0YA 3BBDA 3NK6A 4YPYA 4PZKA 3AI9X 4MCCA 1IPAA 1J85A 4YQSA 4E8BA 4YVGA 4YQRA 4RG1A 2V3JA 4FAKA 3KTYA 1VHYA 1V2XA 1UAMA 4YQOA 4YQ2A 4YQCA 4YQ8A 4YQDA 4YQTA 4YQIA 1VH0A 3KW2A 4MCBA 3N4KA 4H3ZA 4YQ7A 5D9FA 4YQ3A 4YVJA 5GMBA 4JWJA 3QUVA 1O6DA 3OINA 4X3LA 4YVHA 4YQQA 5FAIA 1VHKA 3AIAA 4XBOA 1MXIA 4CNEA 3AXZA 3O7BA 4YQKA 3DCMX 4YQBA 4KDZA 4JWGA 3IEFA 3IC6A 3NK7A 2I6DA 4YQ4A 4L69A 4YQNA 4JWHA 3GYQA 4CNFA 4KGNA 1NXZA 4H3YA 2YY8A 2O3AA 4YQPA 4FMWA 4X3MA 1UAKA 4YQGA 3N4JA 3OIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X7P A;  1UAJ A;  4YQJ A;  4JAL A;  2EGW A;  1GZ0 A;  4YQ5 A;  2EGV A;  4YQ9 A;  4YPZ A;  4YQL A;  1V6Z A;  3ONP A;  3OIJ A;  4IG6 A;  4J3C A;  4YQ1 A;  2V3K A;  2QWV A;  3ILK A;  1P9P A;  2QMM A;  4YPX A;  4YVI A;  1Z85 A;  1OY5 A;  5GM8 A;  1X7O A;  1ZJR A;  1K3R A;  3L8U A;  2CX8 A;  3BBE A;  4YVK A;  3KY7 A;  4CND A;  2HA8 A;  5CO4 A;  5GMC A;  4CNG A;  4JAK A;  1NS5 A;  1TO0 A;  4YQA A;  4MCD A;  3E5Y A;  4YQ0 A;  3KNU A;  4YPW A;  4YQ6 A;  3BBH A;  1UAL A;  2Z0Y A;  3BBD A;  3NK6 A;  4YPY A;  4PZK A;  3AI9 X;  4MCC A;  1IPA A;  1J85 A;  4YQS A;  4E8B A;  4YVG A;  4YQR A;  4RG1 A;  2V3J A;  4FAK A;  3KTY A;  1VHY A;  1V2X A;  1UAM A;  4YQO A;  4YQ2 A;  4YQC A;  4YQ8 A;  4YQD A;  4YQT A;  4YQI A;  1VH0 A;  3KW2 A;  4MCB A;  3N4K A;  4H3Z A;  4YQ7 A;  5D9F A;  4YQ3 A;  4YVJ A;  5GMB A;  3QUV A;  1O6D A;  3OIN A;  4X3L A;  4YVH A;  4YQQ A;  5FAI A;  1VHK A;  3AIA A;  4XBO A;  1MXI A;  4CNE A;  3AXZ A;  3O7B A;  4YQK A;  3DCM X;  4YQB A;  4KDZ A;  3IEF A;  3IC6 A;  3NK7 A;  2I6D A;  4YQ4 A;  4L69 A;  4YQN A;  3GYQ A;  4CNF A;  4KGN A;  1NXZ A;  4H3Y A;  2YY8 A;  2O3A A;  4YQP A;  4X3M A;  1UAK A;  4YQG A;  3N4J A;  3OII A; 
#chains in the Genus database with same CATH topology
 3KOR A;  1UAJ A;  4YQJ A;  1X7P A;  4JAL A;  2EGW A;  1GZ0 A;  4YQ5 A;  2EGV A;  4YQ9 A;  4YPZ A;  4JWF A;  4YQL A;  1V6Z A;  3ONP A;  3OIJ A;  1MI7 R;  4IG6 A;  4J3C A;  4YQ1 A;  1RCS A;  2QWV A;  2V3K A;  3ILK A;  1P9P A;  2QMM A;  4YPX A;  4YVI A;  1Z85 A;  1OY5 A;  5GM8 A;  1X7O A;  1WRP R;  1K3R A;  1ZJR A;  3L8U A;  2CX8 A;  3BBE A;  4YVK A;  3KY7 A;  4CND A;  2HA8 A;  5CO4 A;  5GMC A;  4CNG A;  1JHG A;  4JAK A;  1NS5 A;  1TO0 A;  4YQA A;  3FRW A;  4MCD A;  3E5Y A;  4YQ0 A;  1CO0 A;  3KNU A;  4YPW A;  4YQ6 A;  3BBH A;  1UAL A;  2Z0Y A;  3BBD A;  1TRR A;  3NK6 A;  4YPY A;  1ZT9 A;  4PZK A;  3AI9 X;  4MCC A;  1IPA A;  1J85 A;  4YQS A;  4E8B A;  4YVG A;  4YQR A;  4RG1 A;  2V3J A;  4FAK A;  3KTY A;  1VHY A;  1UAM A;  1V2X A;  4YQO A;  4YQ2 A;  4YQC A;  4YQ8 A;  4YQD A;  4YQT A;  4YQI A;  1VH0 A;  3KW2 A;  4MCB A;  3N4K A;  2OZ9 R;  4H3Z A;  4YQ7 A;  5D9F A;  4YQ3 A;  4YVJ A;  5GMB A;  4JWJ A;  3QUV A;  1O6D A;  3WRP A;  3OIN A;  4X3L A;  4YVH A;  4YQQ A;  5FAI A;  1VHK A;  3G1C A;  3AIA A;  4XBO A;  1MXI A;  4CNE A;  3AXZ A;  3O7B A;  4YQK A;  3DCM X;  4YQB A;  4KDZ A;  4JWG A;  3SSW N;  1WRS R;  3IEF A;  3IC6 A;  3NK7 A;  3SSX N;  2I6D A;  4YQ4 A;  4L69 A;  1TRO A;  4YQN A;  4JWH A;  3GYQ A;  1WRT R;  4CNF A;  4KGN A;  1NXZ A;  4H3Y A;  2YY8 A;  2XDI A;  4YQP A;  2O3A A;  4FMW A;  4X3M A;  1UAK A;  4YQG A;  3N4J A;  3OII A; 
#chains in the Genus database with same CATH homology
 1X7P A;  1UAJ A;  4YQJ A;  4JAL A;  2EGW A;  1GZ0 A;  4YQ5 A;  2EGV A;  4YQ9 A;  4YPZ A;  4JWF A;  4YQL A;  1V6Z A;  3ONP A;  3OIJ A;  4IG6 A;  4J3C A;  4YQ1 A;  2V3K A;  2QWV A;  3ILK A;  1P9P A;  2QMM A;  4YPX A;  4YVI A;  1Z85 A;  1OY5 A;  5GM8 A;  1X7O A;  1ZJR A;  1K3R A;  3L8U A;  2CX8 A;  3BBE A;  4YVK A;  3KY7 A;  4CND A;  2HA8 A;  5CO4 A;  5GMC A;  4CNG A;  4JAK A;  1NS5 A;  1TO0 A;  4YQA A;  4MCD A;  3E5Y A;  4YQ0 A;  3KNU A;  4YPW A;  4YQ6 A;  3BBH A;  1UAL A;  2Z0Y A;  3BBD A;  3NK6 A;  4YPY A;  4PZK A;  3AI9 X;  4MCC A;  1IPA A;  1J85 A;  4YQS A;  4E8B A;  4YVG A;  4YQR A;  4RG1 A;  2V3J A;  4FAK A;  3KTY A;  1VHY A;  1V2X A;  1UAM A;  4YQO A;  4YQ2 A;  4YQC A;  4YQ8 A;  4YQD A;  4YQT A;  4YQI A;  1VH0 A;  3KW2 A;  4MCB A;  3N4K A;  4H3Z A;  4YQ7 A;  5D9F A;  4YQ3 A;  4YVJ A;  5GMB A;  4JWJ A;  3QUV A;  1O6D A;  3OIN A;  4X3L A;  4YVH A;  4YQQ A;  5FAI A;  1VHK A;  3AIA A;  4XBO A;  1MXI A;  4CNE A;  3AXZ A;  3O7B A;  4YQK A;  3DCM X;  4YQB A;  4KDZ A;  4JWG A;  3IEF A;  3IC6 A;  3NK7 A;  2I6D A;  4YQ4 A;  4L69 A;  4YQN A;  4JWH A;  3GYQ A;  4CNF A;  4KGN A;  1NXZ A;  4H3Y A;  2YY8 A;  2O3A A;  4YQP A;  4FMW A;  4X3M A;  1UAK A;  4YQG A;  3N4J A;  3OII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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